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The map label for this gene is yycG [H]

Identifier: 108762821

GI number: 108762821

Start: 805921

End: 807516

Strand: Reverse

Name: yycG [H]

Synonym: MXAN_0706

Alternate gene names: 108762821

Gene position: 807516-805921 (Counterclockwise)

Preceding gene: 108762799

Following gene: 108760900

Centisome position: 8.84

GC content: 69.17

Gene sequence:

>1596_bases
TTGAAGAAGGTCCGAGACACGGGAGAGCCCCCGCTCCAGGGGAGGGAGCGCGCCATGGCGGAGAGGGAGCCGGGCCTCGA
CGCAGCGGGGGACGTCAGCCCGCCTGCCCGGGGTGGACATGACGCGCTGGTCGACAATGTCGACGGCATCGTCTGGGAGG
CAGACCCCTCCGTCCGCTTCATCTTCGTGAGCAAGCAGGCGGAGCGGCTGCTCGGCTATCCGGTGGAGCAGTGGCTCACC
GAGCCTCACTTCTGGTTGGAGCACCTGCATCCAGACGACCGGGCCTGGGCCTCCACCTATTGCCACACCGCGGTGGAGCA
GTGCCTTCCCCACGAATTCGAATACCGGATGCTGGCCGCGGACGGCCGCGTCGTCTGGCTGCGTGACATCGTCACCGTGC
TGTCCAAGGACGGCCGCGCCCACCGGCTTCAAGGCGTCATGGTGGACGTCACCGAGCAGCATCAGGCCCAGGAGCGGCTG
GAGCAGACGGTGTCCCTGCTGGAGGCCACGCTCGACTCGACGGCGGACGGACTGCTGGTGGTCGACCGGGACGGACACAT
CACCGCCTGCAACCGCCAATTCGAGCAGCTCTGGGGACTGACGGGACTGGCTGCCTGCACGCACGACGCGACGCTGCTCG
CGGCCGTGCGCGAGAAGTTGAAGGCCCCGGACGCCTTCTTGTCGCGGGTCCAGTCCCTGTACGAGGAGCCAAGCCAGGAG
AGCTTCGACATCATCGAACTGCGCAACGGCCGCATCCTGGAGCGCTACTCCCTGCCTCAGCGGCGGCGCGGGCTCATCAC
CGGCCGCGTCTGGAGCTTCCGCGACGTCACCGAGCGCGTGCACGCACAGCGCACGCAGGAGCGGCTGCTGGCCGAGGCGC
ACGAGGCCATTCGCGTGCGCGACGACTTCCTCTCCATCGCCGCCCACGAGCTCAAGACGCCCCTGACGCCGCTGCGCCTC
CACCTGGAGCTGCTGAAGCGGGCGCTGGCGGCCAGGGAGCCCATCGCGCCCGAGCGCGTGGACAAGGCCATGGCGCAGGT
GGACCGCCTGTCCGCGCTGGTCAATGATCTGGTGGACGCCACCAGCGTGGAGGCGGGCCGGCTGAAGCTGCAACGCAAAC
CCGTGTCGCTCCTGGAGGTGGCGAACGAAGCGTGCTCGGAGTTCCGTGGCCTCAGCGCGGAGCATGCCTTCATGTGCGAG
CTCCCCCAGGAGGACCTCCTCGTCATGGGCGACCGGGGCCGGCTGTCACAGGTGCTGGCCAACCTCCTGGAGAACGCCGT
CAAATACAGCCCGCTGGGCGGCACCGTGCGCGTCTCCCTGTCTCACGTGGACGGCAACGCCGTGCTCAGCGTGGCGGACG
GTGGCATCGGCATCTCCCGGGAGGAGCAGGCGCACCTCTTCGGCCGCTTCTTCCGCGCGAGCAACGCGCCCGTATCCGGC
TTCGGGGGCCTGGGCCTGGGGCTCTACATCTGCCGGGACATCATCGAACGGCACGGCGGTCACATCTGGGTGGACAGCGA
GCTGGGCCGAGGCTCCACGTTCCATGTCTCGCTGCCCGTGCTGACCGCGACGGCGCAATGGGAGGCCCGGCCCTGA

Upstream 100 bases:

>100_bases
TGCCCCAGGGCGCCCCGGCCTGCCCGGTTCCGGAGATTCGGCGGACGATGCACCCCTGGCCGTAAGGGGCCGGTGGCGCC
CGGCTCCCCGGGTGTATTGA

Downstream 100 bases:

>100_bases
CGCGGCTCACCGCAGGACCGAGCCACTGCTGAGCCGCGACACGGCGCCGTGCAACATGCCCAACTGGCGGGGCACCCGTT
CGAGCAACGCGCCGAAGACG

Product: sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MKKVRDTGEPPLQGRERAMAEREPGLDAAGDVSPPARGGHDALVDNVDGIVWEADPSVRFIFVSKQAERLLGYPVEQWLT
EPHFWLEHLHPDDRAWASTYCHTAVEQCLPHEFEYRMLAADGRVVWLRDIVTVLSKDGRAHRLQGVMVDVTEQHQAQERL
EQTVSLLEATLDSTADGLLVVDRDGHITACNRQFEQLWGLTGLAACTHDATLLAAVREKLKAPDAFLSRVQSLYEEPSQE
SFDIIELRNGRILERYSLPQRRRGLITGRVWSFRDVTERVHAQRTQERLLAEAHEAIRVRDDFLSIAAHELKTPLTPLRL
HLELLKRALAAREPIAPERVDKAMAQVDRLSALVNDLVDATSVEAGRLKLQRKPVSLLEVANEACSEFRGLSAEHAFMCE
LPQEDLLVMGDRGRLSQVLANLLENAVKYSPLGGTVRVSLSHVDGNAVLSVADGGIGISREEQAHLFGRFFRASNAPVSG
FGGLGLGLYICRDIIERHGGHIWVDSELGRGSTFHVSLPVLTATAQWEARP

Sequences:

>Translated_531_residues
MKKVRDTGEPPLQGRERAMAEREPGLDAAGDVSPPARGGHDALVDNVDGIVWEADPSVRFIFVSKQAERLLGYPVEQWLT
EPHFWLEHLHPDDRAWASTYCHTAVEQCLPHEFEYRMLAADGRVVWLRDIVTVLSKDGRAHRLQGVMVDVTEQHQAQERL
EQTVSLLEATLDSTADGLLVVDRDGHITACNRQFEQLWGLTGLAACTHDATLLAAVREKLKAPDAFLSRVQSLYEEPSQE
SFDIIELRNGRILERYSLPQRRRGLITGRVWSFRDVTERVHAQRTQERLLAEAHEAIRVRDDFLSIAAHELKTPLTPLRL
HLELLKRALAAREPIAPERVDKAMAQVDRLSALVNDLVDATSVEAGRLKLQRKPVSLLEVANEACSEFRGLSAEHAFMCE
LPQEDLLVMGDRGRLSQVLANLLENAVKYSPLGGTVRVSLSHVDGNAVLSVADGGIGISREEQAHLFGRFFRASNAPVSG
FGGLGLGLYICRDIIERHGGHIWVDSELGRGSTFHVSLPVLTATAQWEARP
>Mature_531_residues
MKKVRDTGEPPLQGRERAMAEREPGLDAAGDVSPPARGGHDALVDNVDGIVWEADPSVRFIFVSKQAERLLGYPVEQWLT
EPHFWLEHLHPDDRAWASTYCHTAVEQCLPHEFEYRMLAADGRVVWLRDIVTVLSKDGRAHRLQGVMVDVTEQHQAQERL
EQTVSLLEATLDSTADGLLVVDRDGHITACNRQFEQLWGLTGLAACTHDATLLAAVREKLKAPDAFLSRVQSLYEEPSQE
SFDIIELRNGRILERYSLPQRRRGLITGRVWSFRDVTERVHAQRTQERLLAEAHEAIRVRDDFLSIAAHELKTPLTPLRL
HLELLKRALAAREPIAPERVDKAMAQVDRLSALVNDLVDATSVEAGRLKLQRKPVSLLEVANEACSEFRGLSAEHAFMCE
LPQEDLLVMGDRGRLSQVLANLLENAVKYSPLGGTVRVSLSHVDGNAVLSVADGGIGISREEQAHLFGRFFRASNAPVSG
FGGLGLGLYICRDIIERHGGHIWVDSELGRGSTFHVSLPVLTATAQWEARP

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=224, Percent_Identity=34.8214285714286, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788713, Length=381, Percent_Identity=27.2965879265092, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI145693157, Length=259, Percent_Identity=32.8185328185328, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI48994928, Length=395, Percent_Identity=28.3544303797468, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789149, Length=266, Percent_Identity=31.203007518797, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786912, Length=298, Percent_Identity=30.5369127516779, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1788549, Length=401, Percent_Identity=25.6857855361596, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1786600, Length=378, Percent_Identity=26.1904761904762, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786783, Length=251, Percent_Identity=26.2948207171315, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790551, Length=246, Percent_Identity=32.1138211382114, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1790436, Length=242, Percent_Identity=30.5785123966942, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87081816, Length=247, Percent_Identity=30.3643724696356, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082128, Length=223, Percent_Identity=28.2511210762332, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=227, Percent_Identity=29.9559471365639, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=30.0448430493274, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790861, Length=236, Percent_Identity=27.9661016949153, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788279, Length=216, Percent_Identity=26.8518518518519, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59136; Mature: 59136

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVRDTGEPPLQGRERAMAEREPGLDAAGDVSPPARGGHDALVDNVDGIVWEADPSVRF
CCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEECCCCEEE
IFVSKQAERLLGYPVEQWLTEPHFWLEHLHPDDRAWASTYCHTAVEQCLPHEFEYRMLAA
EEECCHHHHHHCCCHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEC
DGRVVWLRDIVTVLSKDGRAHRLQGVMVDVTEQHQAQERLEQTVSLLEATLDSTADGLLV
CCCEEHHHHHHHHHCCCCCCEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VDRDGHITACNRQFEQLWGLTGLAACTHDATLLAAVREKLKAPDAFLSRVQSLYEEPSQE
EECCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
SFDIIELRNGRILERYSLPQRRRGLITGRVWSFRDVTERVHAQRTQERLLAEAHEAIRVR
CCCEEEECCCCEEEHHCCCHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DDFLSIAAHELKTPLTPLRLHLELLKRALAAREPIAPERVDKAMAQVDRLSALVNDLVDA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TSVEAGRLKLQRKPVSLLEVANEACSEFRGLSAEHAFMCELPQEDLLVMGDRGRLSQVLA
CCCCHHHEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEECCCCHHHHHHH
NLLENAVKYSPLGGTVRVSLSHVDGNAVLSVADGGIGISREEQAHLFGRFFRASNAPVSG
HHHHHHHEECCCCCEEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCC
FGGLGLGLYICRDIIERHGGHIWVDSELGRGSTFHVSLPVLTATAQWEARP
CCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECEEEEECCCCCCC
>Mature Secondary Structure
MKKVRDTGEPPLQGRERAMAEREPGLDAAGDVSPPARGGHDALVDNVDGIVWEADPSVRF
CCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEECCCCEEE
IFVSKQAERLLGYPVEQWLTEPHFWLEHLHPDDRAWASTYCHTAVEQCLPHEFEYRMLAA
EEECCHHHHHHCCCHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEC
DGRVVWLRDIVTVLSKDGRAHRLQGVMVDVTEQHQAQERLEQTVSLLEATLDSTADGLLV
CCCEEHHHHHHHHHCCCCCCEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VDRDGHITACNRQFEQLWGLTGLAACTHDATLLAAVREKLKAPDAFLSRVQSLYEEPSQE
EECCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
SFDIIELRNGRILERYSLPQRRRGLITGRVWSFRDVTERVHAQRTQERLLAEAHEAIRVR
CCCEEEECCCCEEEHHCCCHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DDFLSIAAHELKTPLTPLRLHLELLKRALAAREPIAPERVDKAMAQVDRLSALVNDLVDA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TSVEAGRLKLQRKPVSLLEVANEACSEFRGLSAEHAFMCELPQEDLLVMGDRGRLSQVLA
CCCCHHHEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEECCCCHHHHHHH
NLLENAVKYSPLGGTVRVSLSHVDGNAVLSVADGGIGISREEQAHLFGRFFRASNAPVSG
HHHHHHHEECCCCCEEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCC
FGGLGLGLYICRDIIERHGGHIWVDSELGRGSTFHVSLPVLTATAQWEARP
CCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]