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The map label for this gene is wecB [H]

Identifier: 108762812

GI number: 108762812

Start: 1282076

End: 1283206

Strand: Direct

Name: wecB [H]

Synonym: MXAN_1101

Alternate gene names: 108762812

Gene position: 1282076-1283206 (Clockwise)

Preceding gene: 108759404

Following gene: 108758129

Centisome position: 14.03

GC content: 67.82

Gene sequence:

>1131_bases
ATGAAGAAGGTCATTCATATCGTTGGGGCGCGTCCGAACTTCATGAAGGTCGCGCCCATCTATCGCGCCATCGCCGAGCG
TACTCCCCTTGAGCAAATCCTTGTCCACACGGGGCAACACTATGACGCCAAGATGAGCGACGTGTTCTTCGCCGACCTCG
GCCTGCCTGCCCCGGACGTCCATCTGGGCATCGGGTCGGGCAGCCATGCGCAGCAGACGGCACGCATGATGGTGGAGCTG
GAAAAGGTTTTCCTGGCCCACCCTCCGGCGCTCGTCTCCGTGGTGGGCGACGTGAACAGCACCATCGCGGCGGCGTTGGT
GACGTCGAAGCTGGGCATCCCCCTGGCACACGTCGAAGCGGGGCTGCGCAGCTACTCGCCACACCAACCGGAGGAGATCA
ACCGGCTCGTCACCGACCGCCTGTCGGACCTGCTGCTGACGCCTTCACGTGACGCGGACGCCAACCTGCTCAAGGAAGGC
ACCGACCCGGCCCGCATCCACTTCGTGGGCAACGTGATGATCGACTCGCTCTTCGCCTCGCGCGAGAAGGCCGACAAGCT
GCCGGTGCTCAAGGACCTGGGGCTCATCCCCCACGGCTACGCGGTGTGCACGCTGCACCGGCCCTCCAACGTGGACGACC
CCAAGACTCTGGGCGGCCTCCTGTCCGCGGTGGCCCACGTCGCCACGCGCCTGCCGGTCATCTTCCCGGTGCACCCGCGC
ACGCGGAAGGTGATTTCGGAGCATGGCCTGAACACGTGGTTCGAGCGCACGCCGAGCCTGCGGCCCGTGGAGCCCATGGG
CTACCTCGACTTCCTGGCGCTCACGTCGAAGGCGCGCCTGGTGCTCACCGACTCCGGCGGCCTCCAGGAGGAGACGACGG
CCATGGGCGTCCCGTGCCTCACCCTGCGCGAGCAGACCGAGCGCCCCATCACCGTGGAGGAAGGCTCCAACGAGGTGGTG
GGCACCGACCCGGTCCGCATCCGTCTGGCCGCCGACCGCGTGCTGGATGGTGAAGGCAAGCAGGGCCGCGTGCCCGAGTT
CTGGGATGGCCGCGCCGCCGAGCGCATCGCGGACCTGTTCGCGAGCTTCCTGGGCGTCGAGGACCGGCCGATTCAGGCGG
CCTCGGCCTGA

Upstream 100 bases:

>100_bases
CCGTCTATCAGGTTCGCGACGATTGCCGGCCCCCGGGATTGGACATTTGCATCATCGGACACTGGCCAGCGCGGCTCCAG
TGCCTAGCTTTGGTCGCAAC

Downstream 100 bases:

>100_bases
GGGCAAATGACGGGTGGGGGCCCCGGCGTTCCGTGGGCCCGCTCGCTCGTCCGTCCCCGCCTGTGCAGGAGGGCCCGCCG
TGGTAGAGCGCCGGCAGGCC

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MKKVIHIVGARPNFMKVAPIYRAIAERTPLEQILVHTGQHYDAKMSDVFFADLGLPAPDVHLGIGSGSHAQQTARMMVEL
EKVFLAHPPALVSVVGDVNSTIAAALVTSKLGIPLAHVEAGLRSYSPHQPEEINRLVTDRLSDLLLTPSRDADANLLKEG
TDPARIHFVGNVMIDSLFASREKADKLPVLKDLGLIPHGYAVCTLHRPSNVDDPKTLGGLLSAVAHVATRLPVIFPVHPR
TRKVISEHGLNTWFERTPSLRPVEPMGYLDFLALTSKARLVLTDSGGLQEETTAMGVPCLTLREQTERPITVEEGSNEVV
GTDPVRIRLAADRVLDGEGKQGRVPEFWDGRAAERIADLFASFLGVEDRPIQAASA

Sequences:

>Translated_376_residues
MKKVIHIVGARPNFMKVAPIYRAIAERTPLEQILVHTGQHYDAKMSDVFFADLGLPAPDVHLGIGSGSHAQQTARMMVEL
EKVFLAHPPALVSVVGDVNSTIAAALVTSKLGIPLAHVEAGLRSYSPHQPEEINRLVTDRLSDLLLTPSRDADANLLKEG
TDPARIHFVGNVMIDSLFASREKADKLPVLKDLGLIPHGYAVCTLHRPSNVDDPKTLGGLLSAVAHVATRLPVIFPVHPR
TRKVISEHGLNTWFERTPSLRPVEPMGYLDFLALTSKARLVLTDSGGLQEETTAMGVPCLTLREQTERPITVEEGSNEVV
GTDPVRIRLAADRVLDGEGKQGRVPEFWDGRAAERIADLFASFLGVEDRPIQAASA
>Mature_376_residues
MKKVIHIVGARPNFMKVAPIYRAIAERTPLEQILVHTGQHYDAKMSDVFFADLGLPAPDVHLGIGSGSHAQQTARMMVEL
EKVFLAHPPALVSVVGDVNSTIAAALVTSKLGIPLAHVEAGLRSYSPHQPEEINRLVTDRLSDLLLTPSRDADANLLKEG
TDPARIHFVGNVMIDSLFASREKADKLPVLKDLGLIPHGYAVCTLHRPSNVDDPKTLGGLLSAVAHVATRLPVIFPVHPR
TRKVISEHGLNTWFERTPSLRPVEPMGYLDFLALTSKARLVLTDSGGLQEETTAMGVPCLTLREQTERPITVEEGSNEVV
GTDPVRIRLAADRVLDGEGKQGRVPEFWDGRAAERIADLFASFLGVEDRPIQAASA

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=383, Percent_Identity=32.3759791122715, Blast_Score=141, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 40905; Mature: 40905

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVIHIVGARPNFMKVAPIYRAIAERTPLEQILVHTGQHYDAKMSDVFFADLGLPAPDV
CCCEEEEECCCCCCEEHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHEEEECCCCCCCCE
HLGIGSGSHAQQTARMMVELEKVFLAHPPALVSVVGDVNSTIAAALVTSKLGIPLAHVEA
EEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
GLRSYSPHQPEEINRLVTDRLSDLLLTPSRDADANLLKEGTDPARIHFVGNVMIDSLFAS
HHHCCCCCCHHHHHHHHHHHHHHHEECCCCCCCHHHHHCCCCCEEEEEEHHHHHHHHHHH
REKADKLPVLKDLGLIPHGYAVCTLHRPSNVDDPKTLGGLLSAVAHVATRLPVIFPVHPR
HHHHHCCCHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCH
TRKVISEHGLNTWFERTPSLRPVEPMGYLDFLALTSKARLVLTDSGGLQEETTAMGVPCL
HHHHHHHCCCHHHHHCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCHHHHCCCCEE
TLREQTERPITVEEGSNEVVGTDPVRIRLAADRVLDGEGKQGRVPEFWDGRAAERIADLF
HHHHHCCCCEEEECCCCCEECCCCEEEEEEECCEECCCCCCCCCCCCCCCHHHHHHHHHH
ASFLGVEDRPIQAASA
HHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKKVIHIVGARPNFMKVAPIYRAIAERTPLEQILVHTGQHYDAKMSDVFFADLGLPAPDV
CCCEEEEECCCCCCEEHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHEEEECCCCCCCCE
HLGIGSGSHAQQTARMMVELEKVFLAHPPALVSVVGDVNSTIAAALVTSKLGIPLAHVEA
EEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
GLRSYSPHQPEEINRLVTDRLSDLLLTPSRDADANLLKEGTDPARIHFVGNVMIDSLFAS
HHHCCCCCCHHHHHHHHHHHHHHHEECCCCCCCHHHHHCCCCCEEEEEEHHHHHHHHHHH
REKADKLPVLKDLGLIPHGYAVCTLHRPSNVDDPKTLGGLLSAVAHVATRLPVIFPVHPR
HHHHHCCCHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCH
TRKVISEHGLNTWFERTPSLRPVEPMGYLDFLALTSKARLVLTDSGGLQEETTAMGVPCL
HHHHHHHCCCHHHHHCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCHHHHCCCCEE
TLREQTERPITVEEGSNEVVGTDPVRIRLAADRVLDGEGKQGRVPEFWDGRAAERIADLF
HHHHHCCCCEEEECCCCCEECCCCEEEEEEECCEECCCCCCCCCCCCCCCHHHHHHHHHH
ASFLGVEDRPIQAASA
HHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA