Click here to switch to the map view.

The map label for this gene is yeaE [H]

Identifier: 108759404

GI number: 108759404

Start: 1279428

End: 1280276

Strand: Direct

Name: yeaE [H]

Synonym: MXAN_1098

Alternate gene names: 108759404

Gene position: 1279428-1280276 (Clockwise)

Preceding gene: 108762286

Following gene: 108762812

Centisome position: 14.0

GC content: 71.14

Gene sequence:

>849_bases
ATGGAGCAGCGTCCATTCGGAAGCACACGGGTGTCCGTGCCCGTCCTGGGCCAGGGGACCTGGCAGATGGAGGAGGATGA
CCGGGCAGGCGCCATCCGCGCCCTTCGCGCCGGGTTGGACCTGGGAATGACGCACGTGGACACCGCTGAACTGTACGGCT
ACGGCAAGGTGGAGGAGTCCATCGTCTCCGAGGCCATCGCGGGCCGGCGCGGCGACGTCTTCCTGGTGTCGAAGGTGATG
CCGTCCAACGCTTCCTACGCGGGCACGCTCGCCGCCTGTGAGCGGAGCCTGAAGCGGCTGCGCACGGACCACCTCGACTG
CTACCTGCTGCACTGGCCGGGTTCGCACCCGCTGGAGGAGACGGTGCGCGCCTTCGAGAAGCTGGTGGTGGATGGAAAGA
TTCGCGCCTGGGGCGTGAGCAACTTCGGGGTGGAGGACCTGGAGGAGGCGCTCGCGCTCGCGGGGCCCGGGCGCATCGCC
TGCAACCAGGTGCTCTACCACCTGGAGGAGCGCGCCATTGAGCACGCCGTCCTGCCCTGGTGCGAAGCCCACGGGGTGGC
GGTGGTGGGCTACAGCCCCTTCGGCAACGGCCGTTTTCCCCGGCCCGACAGCCGGGGTGGGAAGGTGCTGGGCGGCATCG
CCCGCGCGCACGGCGTCACGCCGTACCAGGTGGCGCTCCGGTTCCTGGTGCGCGGGCCGTCGCTGTTCGCCATCCCCAAG
GCGAGCCGGGAAGCCCACGCACGCGACAACGCCGCCGCCGCGTCGCTGACGCTGACCGCCGACGAGCTGGCCCACCTCGA
CGCGGCCTTCCCGCTGGGGCCCGAGCCGGCGTCGCTGCCCGTCATCTGA

Upstream 100 bases:

>100_bases
CTAACGCGAGCTTCCAACCTGCGCACCGGACGCCTGCGTGTGCGTTGAAGCGGTATTAATCCTCTCGAAGCAAGTCATAC
GCCGAATCAGGGGGAGTGCC

Downstream 100 bases:

>100_bases
TGCCGGCGGCGAAGGCCTTGCGGAAGGCGGACACGGTGGGCTCACCCGGGCCCACCGTCACCGTGCCCGTCTCGCCCTCC
ACGGCGGCGCGGGTGTCGCG

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MEQRPFGSTRVSVPVLGQGTWQMEEDDRAGAIRALRAGLDLGMTHVDTAELYGYGKVEESIVSEAIAGRRGDVFLVSKVM
PSNASYAGTLAACERSLKRLRTDHLDCYLLHWPGSHPLEETVRAFEKLVVDGKIRAWGVSNFGVEDLEEALALAGPGRIA
CNQVLYHLEERAIEHAVLPWCEAHGVAVVGYSPFGNGRFPRPDSRGGKVLGGIARAHGVTPYQVALRFLVRGPSLFAIPK
ASREAHARDNAAAASLTLTADELAHLDAAFPLGPEPASLPVI

Sequences:

>Translated_282_residues
MEQRPFGSTRVSVPVLGQGTWQMEEDDRAGAIRALRAGLDLGMTHVDTAELYGYGKVEESIVSEAIAGRRGDVFLVSKVM
PSNASYAGTLAACERSLKRLRTDHLDCYLLHWPGSHPLEETVRAFEKLVVDGKIRAWGVSNFGVEDLEEALALAGPGRIA
CNQVLYHLEERAIEHAVLPWCEAHGVAVVGYSPFGNGRFPRPDSRGGKVLGGIARAHGVTPYQVALRFLVRGPSLFAIPK
ASREAHARDNAAAASLTLTADELAHLDAAFPLGPEPASLPVI
>Mature_282_residues
MEQRPFGSTRVSVPVLGQGTWQMEEDDRAGAIRALRAGLDLGMTHVDTAELYGYGKVEESIVSEAIAGRRGDVFLVSKVM
PSNASYAGTLAACERSLKRLRTDHLDCYLLHWPGSHPLEETVRAFEKLVVDGKIRAWGVSNFGVEDLEEALALAGPGRIA
CNQVLYHLEERAIEHAVLPWCEAHGVAVVGYSPFGNGRFPRPDSRGGKVLGGIARAHGVTPYQVALRFLVRGPSLFAIPK
ASREAHARDNAAAASLTLTADELAHLDAAFPLGPEPASLPVI

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI310109922, Length=270, Percent_Identity=32.2222222222222, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI223468663, Length=291, Percent_Identity=27.8350515463918, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI5453543, Length=290, Percent_Identity=30.6896551724138, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI310109920, Length=290, Percent_Identity=30.6896551724138, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI45446745, Length=290, Percent_Identity=30.3448275862069, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI4503285, Length=290, Percent_Identity=30.3448275862069, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI24497585, Length=288, Percent_Identity=29.8611111111111, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI24497577, Length=287, Percent_Identity=27.8745644599303, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI5174391, Length=287, Percent_Identity=27.8745644599303, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI24497583, Length=288, Percent_Identity=30.5555555555556, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI291291012, Length=264, Percent_Identity=28.030303030303, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI5174695, Length=291, Percent_Identity=26.8041237113402, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI4502049, Length=299, Percent_Identity=26.4214046822742, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI300116273, Length=277, Percent_Identity=27.0758122743682, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI27436964, Length=220, Percent_Identity=28.1818181818182, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI27436962, Length=220, Percent_Identity=28.1818181818182, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI27436966, Length=220, Percent_Identity=28.1818181818182, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI27436969, Length=216, Percent_Identity=27.3148148148148, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI4504825, Length=213, Percent_Identity=27.2300469483568, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1788081, Length=274, Percent_Identity=47.4452554744526, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI1786400, Length=268, Percent_Identity=29.1044776119403, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI87081735, Length=322, Percent_Identity=30.4347826086957, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87082198, Length=278, Percent_Identity=29.4964028776978, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1787674, Length=291, Percent_Identity=30.5841924398625, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1788070, Length=315, Percent_Identity=27.3015873015873, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1789375, Length=321, Percent_Identity=26.4797507788162, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537077, Length=287, Percent_Identity=30.3135888501742, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17564128, Length=295, Percent_Identity=30.1694915254237, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17552492, Length=285, Percent_Identity=27.0175438596491, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17537075, Length=286, Percent_Identity=29.3706293706294, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17550248, Length=290, Percent_Identity=27.9310344827586, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71998625, Length=274, Percent_Identity=25.9124087591241, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17566692, Length=291, Percent_Identity=27.4914089347079, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538386, Length=273, Percent_Identity=26.3736263736264, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17561300, Length=206, Percent_Identity=27.1844660194175, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17561298, Length=290, Percent_Identity=25.5172413793103, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324694, Length=283, Percent_Identity=28.6219081272085, Blast_Score=90, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320079, Length=276, Percent_Identity=25.7246376811594, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322556, Length=270, Percent_Identity=24.8148148148148, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24663317, Length=287, Percent_Identity=28.5714285714286, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI45553081, Length=286, Percent_Identity=30.4195804195804, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24644950, Length=295, Percent_Identity=29.4915254237288, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI281366140, Length=258, Percent_Identity=30.2325581395349, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI20129731, Length=283, Percent_Identity=29.6819787985866, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24657054, Length=282, Percent_Identity=27.3049645390071, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24662789, Length=279, Percent_Identity=26.8817204301075, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24662781, Length=278, Percent_Identity=25.8992805755396, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24662785, Length=278, Percent_Identity=25.5395683453237, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 30366; Mature: 30366

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQRPFGSTRVSVPVLGQGTWQMEEDDRAGAIRALRAGLDLGMTHVDTAELYGYGKVEES
CCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHH
IVSEAIAGRRGDVFLVSKVMPSNASYAGTLAACERSLKRLRTDHLDCYLLHWPGSHPLEE
HHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
TVRAFEKLVVDGKIRAWGVSNFGVEDLEEALALAGPGRIACNQVLYHLEERAIEHAVLPW
HHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCH
CEAHGVAVVGYSPFGNGRFPRPDSRGGKVLGGIARAHGVTPYQVALRFLVRGPSLFAIPK
HHHCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECC
ASREAHARDNAAAASLTLTADELAHLDAAFPLGPEPASLPVI
CCCHHHCCCCCCCEEEEEEHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEQRPFGSTRVSVPVLGQGTWQMEEDDRAGAIRALRAGLDLGMTHVDTAELYGYGKVEES
CCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHH
IVSEAIAGRRGDVFLVSKVMPSNASYAGTLAACERSLKRLRTDHLDCYLLHWPGSHPLEE
HHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
TVRAFEKLVVDGKIRAWGVSNFGVEDLEEALALAGPGRIACNQVLYHLEERAIEHAVLPW
HHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCH
CEAHGVAVVGYSPFGNGRFPRPDSRGGKVLGGIARAHGVTPYQVALRFLVRGPSLFAIPK
HHHCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECC
ASREAHARDNAAAASLTLTADELAHLDAAFPLGPEPASLPVI
CCCHHHCCCCCCCEEEEEEHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]