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The map label for this gene is eryA [H]

Identifier: 108762792

GI number: 108762792

Start: 5267740

End: 5273229

Strand: Reverse

Name: eryA [H]

Synonym: MXAN_4297

Alternate gene names: 108762792

Gene position: 5273229-5267740 (Counterclockwise)

Preceding gene: 108760636

Following gene: 108761108

Centisome position: 57.7

GC content: 70.04

Gene sequence:

>5490_bases
ATGGCGAAACTATCTACACGCATTTCCGAATTGCCTGTCGTCAAGCTCGCGTACCTCGCGAGCCAGCTGCGCTCGAAGAA
GGAGCTGCTGGCGGCCGAGCCCATCGCCGTGGTGGGCATGTCCTGTCGCTTCCCCGGCGGAGGTGACCTGCCAGAGACGT
TCTGGGAGCTGCTCGCCGAGGGCCGCGACGCGACACGGGAGGTGCCCGCCTCACGCTGGGACGTCGACGCGTTCTACGAC
CCCACGCCCGGTGTCCCGGGAAAGATGTACACGCGCCGAGGCGCCTTCATCGACGGCGTCGACCTGTTCGACCCTGGCTT
CTTCGGCATCACGCCGCGTGATGCCAAGGGCATGGACCCACAGCAGCGCTTGTTGCTGGAGGAGTGCTGGCGAGCCTTGG
AGCGCGCCGGCATCCCACCCGCCGGCCTCACCGGGAGCCGCACCGGCATCTTCCTGGGGCTGATGCACAACGACTACAAC
CTGCTGGGCATCGCCGAGAACATGGAGTTCCACTCGGCGTCGCTCAATTACCCGTCCGTCGCCGCGGGACGCATCTCCCA
CACGCTGGGCCTTCAGGGGCCCGCGGTCTCCGTGGACACGGCGTGCTCGTCGTCCGCGGTGGCCATCCACCTGGCCTGTC
AGAGCCTCCGCAACGACGAGAGCGACCTCGCGCTCGCCGCGGGCGCGAACCTGAACCTCTCTCCCGTCACGGTGATGGTG
GAGTGCCAGAACCGCATGCTGGCGGCGGATGGCCGCTGCAAGACGTTCGACGCCTCCGCGGACGGCTTCGGGCGCGGCGA
GGGTTGCGGCGTCGTCGTGCTCAAGCGCTTGTCGGATGCGCTGGCCCATGGCGATGCCATCCTCGGCGTCATCCGGGGCT
CGGCGGTCACACATGACGGCCGCAGCAGCGGGATGATGGTGCCGAACGGACGCTCGCAGGAGCGCGTCATCCGGGCGGCC
CTGGATAGCTGTGGCGTGGAGCCGGACCAGGTGGGCTACATCGAGGCCCATGGGACGGGGACACTGCTCGGCGACCCCAT
CGAGATGGAGGCGCTGCGGTCCGTCTTCGGGCGCAAGGGCGCTCGCGGTGAGCCGCTGTACGTCGGCTCGGTGAAGACGA
ACATCGGGCACCTGGAGGCAGCCGCCGGTATCGCGGGGCTCATCAAGGTCCTGCTCGCCTTGCAGAACGAGGCCATCCCC
GCCCACCTGAACTTCGAGCGGCCCAATCCGAACATCCGCTGGGACGACCTGCCCGTCACCATCCCCACGGCCACGCGGCC
CTGGCTGCGCGGTGACAAGCGCCGTATCGCGGGCGTCAGCAGCTTCGGCTTCAGCGGCACCAACGTGCACATGGTCGTGG
AGGAAGCCCCCGTGCTGGCGCGGCCCCGCGTGGACGCGGAGCGCCCGGCCCATGTGCTGACGCTGTCGGCGAAGAGCGAA
GCCGCGCTCGAAGCGCTGATGGAAGCGCAGGAACGCGCGTTGCCGGAGGACCCGGCGGCGCTGGGAGACTGGTGCTACAC
GGCGAACACGGGCCGCTCCCAGTTCGAGCACCGCGCCGCTGTTTCGGGCGCCACGGCCGCGGAGCTGCGCGCGAACCTGA
CGCGGCTGCGCGAAGAGAAGCTGCGCCCAGCGCGCGAACCCCTGCGCGGAACGGAGAGCCCCCGGCCTGTCTTCCTCTTC
ACGGGGCAGGGCGCGCTTCGCCCTGGAGTGGGGCGGGAACTCTTCGAGACGCAGCCGGTGTTCCGGGCAGCGGTGGAGCG
GTGCTCGAAGGCGCTGGAGGGCCTGCTCGATTGCAGCCTCGAAGCGCTCCTCTTCGGTGAGTCTTCCGCGATGCTTCTGG
AGGACACGCGCCATGCGCAGCCCGCGCTGGTGGCTCTGGAGTATGCGCTGGCGGAGCTGTGGGGCGCCTGGGGCGTCACG
CCAGCGGCCCTCATCGGGCACAGCCTGGGAGAGTATGCCGCGGCCGCTGTCGCGGGGGTGTTCAGCATCGAGGAGGCGCT
GCGTCTGGTCGTGACGCGTGCGCGGCTCATCGGCGAGCTGCTGGGCCCAGGCGCGATGCTGGCGGTCTCTGCTCCGCTCG
ACACGGTGAACCGGGCCATCGCGCCGCACGCCGGCTCGGTCTCCCTGGCGGCGGTCAACGGCCCTGATGACGTGGTCATC
TCCGGGACGCCCGACGCCATCACCGAGGTGGAGCAGGCGCTGTCGAGCCAGGGCATCCAGACGAAGCGTCTGCGGATGTC
CTACGCCTTCCACTCCACGCAGATGGAGCCCGTGCTGAAGCCGTTCGCCGAGGCCTTCCAAGGGCTCACGCTGTCGGCAC
CGCGCATCCCGCTGGTGTCCACACTGGAGGGCCGGCGTGTCGGCGACGAGGTCTCCCGGCCCGAGTACTGGTGCCGTCAG
ATTCTAGAGCCCGTCGCCTTCGCCAAGGCGCTGGAGGCGTCGCGGGAGGACGGGCACCGGACCTATCTGGAGCTGGGGCC
GGCGCCCATCCTGGCTGGCATTGGCCGCAGGACGTTCCAGTCGGAAGAGCTGTGCTGGCTCCCCAGCCTGCGTCCGTCCA
CCGGAGAGACAGCGCAGCTGCTCTCCAGCGTGGCGGAGCTGTACATGCGTGGCTTCGACGTGGATTGGGCTGCGTTCGAT
GCGCCTTTCGAGCGGCGCCCGCGCTGCTTGCCGACGCATCCCTTCCAACGTGAGCGCTACTGGATGGACTTGCAAAGCCC
CGAGAATCGCCGGGGCTATGCGGCGCGTGACGATGCCGCGCGAGGCGATGCGCACTCCCTGCCGGGGACACCGCTGTCGC
TCGCGGGGGCGAAGGAAACGCGCTTCGCGGCCCGGCTGAGCAGGCACGAGCCCGCTTTCATCGAGGAGCATCGTGTGCTG
GGCAACCCAGTGCTGCCGGCCGCCTGCTACGTCGAGATGGCGCTCGGCGCCGCGCACCACGCGACGTCTGGCGGGAAACC
TCTGGAGCTCACGGCCATCGAGCTGGAGCGGGCGTTGGTCTTCGCCGAGGGACAGTCACAGGACGTCCAGACGGTGCTGA
CGCCCGAGGAGCAGGGCTCTCGCTTCGAAATCTTCGGGCAGGCGACAGGGACGGCGGATCGGAATTGGGCCCGGCTGGCG
CAGGGCCGCATCACCGAGGGCCGCATGAACCCGGAGCACGTGGCCCTGGAGTCGGAGCTGTTGCAGGCGTTCCCCCGGCA
GGGCTCCGTCAGCGCGCACTACGACATGATGGCGCGCGGTGGGTTGGAGTACGGCCCTTCGTTCCGAGGCATCGATGCGC
TGCGGTTCGGCGGGGAGGGATGCCTCGCCCACGTGCGGCTGCCCGATGCGCTCGTCATCGGTTTGGGGGACTACTGGCTG
CATCCGTTGCTGCTCGACGCATGCTTCCAGACGGCGGCGGCGGCGTTCACGGACGGCGGCGCGCAGGTGGCGGGAGAAGG
GCAGGGACGCATTCCGGTCGCCATCGAGCGGCTGCGTTGGTTCAAGCGGCCTGGGAGCAGCATCTGGGTGCACGCCCGAA
CCGGGGCGCGCACGTCGCTCTCGGAGGGACTGGCGAGCGCCGACCTCCGCATCCTGGACGAGGACGGCACCGTCGTCGCC
GAGGTGGAAGGCCTGCTGCTGAAGCAGGTCGACCGCCGCGCGTTCCAGGCGGCCTTCTCGGGGGCGATGCAGGAACTCCT
CTTCGAGCTGGCGTGGCGGGAGCAGCCCGCGCCCTCCGCGCGTGACCAGGTGGCTTCGCAGTCCGGGCCTTGGCTGTTGC
TGGTGGACTCGGATCGCGTCGCGGACGAAGTCAGGACGTTGGCGCGGCAACGCGCTTGGATCTGCGTGGTGGCCACGCCC
GGTGCGTCCTACGAACGCGTCGACGCGAACCACTACCGGCTGAACCCCCATGACGCGGCGGGCTTTGACCGGCTGCTCCA
GGACGTCTCCGCTCCAGCGGCAGTGGCCTATCTGTGGGGGCTCGGCGACCGTTCTCCCGAGGCCCTCTCCGGCGCGGTGA
CGTCGAGCACCTTGGGCGCGCTTCACCTCGTGAAAGCGATGGCGCGTGCCGGCTGGGCGCAGCCGCCTGCCCTCTGGATG
GTGACGGAGAGCGCGGTGGCCGCCACGCCCACGGATGCGGTGGAGGGCTTTGCTCAGGCCTCCCTCTGGGGCTTCGGCCG
CGCTGTGGCCATCGAGCACACGGAGTTCATGTGCCGCATGGTGGACCTGGAGCCGGGCTCCGAATCGCTGGAGCGCTTGT
TCCTCCTCATGGCGCAGCCGCCGCAGGAGAACGTCTTGGCCCTGCGCGGCGGCCGGATCCTGGGCGCGCGCCTCGTGCGT
CCTGGCAAGCCACCTGAACGCGCTGCCCCCGTGCGTATCCGCCCCGATGGCGTCTACCTCGTCACGGGAGGCCTCGGGGC
GCTGGGGCTCGAGACTGCGGAGTGGCTGGTGGGGGCCGGGGCGCGGCACCTGCTGCTGGTGGGACGGAGCGAGCCCACGG
ACGCGGCGAACGCTCGGCTCGCGGCGCTGACCGCCCGGGGCGTCGGCGTCACCGTCGCGCGCGCGGATGTCTCACGACAG
GAGGACGTGCAGCGACTGGTGGCGAGCGTGTCAGAGCGGGGCCTGTCCCTGCGAGGCATCATCCACACGGCGGGCGTGCT
GGAGGACGGCGTCATCCTGCACCAGGATGCGGAGCGCTTCTCGCGCGTGTTCGCGCCCAAGGTGCAGGGCGCGTTGAACC
TGCACCGCGCCACGGCCGGGATGCCGCTGGACCTCTTCGTCATGTACTCGTCCGCGGCCTCGCTGGTGGGCGTGGCGGGA
CAGTCGAACTACGTGGCGGCGAACAGCGTCCTGGACGCACTGGCGCACCACCGGAACCGCCTGGGTCTGCCAGCCCTCAG
CATCAACTGGGGACGGTGGGCGGGCGCGGGCATGGCCGCGAAGAGCGCGGACCGGCCGGAAGCGTCGGATGCCGCCAGCC
TCTCACCCGAAGTGGCGCTCCAGGTCTTCGAACAACTGCTGGAGCAGGGGGCCGTGCAGGTGGGCGTCGTGCCCTTCAGC
GTCTCCTCGCTGGAGGCGGGGCCTTCGCCCGGCCATGGCCCCTTGTTCTCCGAGCTGATGCTCCGTGAGCAGGCCCGGTC
CGCGGCGGCTTCGCGGATGCATGAGCTGATGGAAGAGCTGAAGCGGGCGGACGGGGAGCGCCGGCGCGCGCTGCTGACAC
GGTACGTACAGAGCCGGCTGGGGCCCTTGCTGGGCTTCGCCCCGGACCACGAGGTCCTCCAGAAGAGGATTTCCTTGAAC
GAGATGGGGCTCGATTCGCTGCGCGCGGTCGAGCTGAAGAACCGCATTGGCCGCGAGCTGGGAGTGGACCTGCTCATGGC
GCGTTTCATCGACGGCACCACGCTCGACGGGATTGTGGATGCGCTGAGCACCCAGCTCGAGCTCAAGGAGCTGCTCGCGC
GTGCTCCCGCGGCGGAGGCCGCAGCCGACATCGAGGAGTTGACGGTATGA

Upstream 100 bases:

>100_bases
CAGGGCGCGCTCTCCGCGGAGATTCAAGGGCTGTCGGAGCAGGAGCTGACGTCCCTCATCGACCAGGAGCTGGAGAGCGC
GCTCACCAGATGAGACCCTG

Downstream 100 bases:

>100_bases
ATCTGGGGGAACTGCTCGCCGAGCTGAATCGGCGGGGCCTGGAAGTCCGGGTGGAAGGCGACGCGCTGAGGCTTCGCGGA
CCGAAAGGCGCCGCCACCGC

Product: polyketide synthase

Products: NA

Alternate protein names: 6-deoxyerythronolide B synthase II; DEBS 2; ORF 2 [H]

Number of amino acids: Translated: 1829; Mature: 1828

Protein sequence:

>1829_residues
MAKLSTRISELPVVKLAYLASQLRSKKELLAAEPIAVVGMSCRFPGGGDLPETFWELLAEGRDATREVPASRWDVDAFYD
PTPGVPGKMYTRRGAFIDGVDLFDPGFFGITPRDAKGMDPQQRLLLEECWRALERAGIPPAGLTGSRTGIFLGLMHNDYN
LLGIAENMEFHSASLNYPSVAAGRISHTLGLQGPAVSVDTACSSSAVAIHLACQSLRNDESDLALAAGANLNLSPVTVMV
ECQNRMLAADGRCKTFDASADGFGRGEGCGVVVLKRLSDALAHGDAILGVIRGSAVTHDGRSSGMMVPNGRSQERVIRAA
LDSCGVEPDQVGYIEAHGTGTLLGDPIEMEALRSVFGRKGARGEPLYVGSVKTNIGHLEAAAGIAGLIKVLLALQNEAIP
AHLNFERPNPNIRWDDLPVTIPTATRPWLRGDKRRIAGVSSFGFSGTNVHMVVEEAPVLARPRVDAERPAHVLTLSAKSE
AALEALMEAQERALPEDPAALGDWCYTANTGRSQFEHRAAVSGATAAELRANLTRLREEKLRPAREPLRGTESPRPVFLF
TGQGALRPGVGRELFETQPVFRAAVERCSKALEGLLDCSLEALLFGESSAMLLEDTRHAQPALVALEYALAELWGAWGVT
PAALIGHSLGEYAAAAVAGVFSIEEALRLVVTRARLIGELLGPGAMLAVSAPLDTVNRAIAPHAGSVSLAAVNGPDDVVI
SGTPDAITEVEQALSSQGIQTKRLRMSYAFHSTQMEPVLKPFAEAFQGLTLSAPRIPLVSTLEGRRVGDEVSRPEYWCRQ
ILEPVAFAKALEASREDGHRTYLELGPAPILAGIGRRTFQSEELCWLPSLRPSTGETAQLLSSVAELYMRGFDVDWAAFD
APFERRPRCLPTHPFQRERYWMDLQSPENRRGYAARDDAARGDAHSLPGTPLSLAGAKETRFAARLSRHEPAFIEEHRVL
GNPVLPAACYVEMALGAAHHATSGGKPLELTAIELERALVFAEGQSQDVQTVLTPEEQGSRFEIFGQATGTADRNWARLA
QGRITEGRMNPEHVALESELLQAFPRQGSVSAHYDMMARGGLEYGPSFRGIDALRFGGEGCLAHVRLPDALVIGLGDYWL
HPLLLDACFQTAAAAFTDGGAQVAGEGQGRIPVAIERLRWFKRPGSSIWVHARTGARTSLSEGLASADLRILDEDGTVVA
EVEGLLLKQVDRRAFQAAFSGAMQELLFELAWREQPAPSARDQVASQSGPWLLLVDSDRVADEVRTLARQRAWICVVATP
GASYERVDANHYRLNPHDAAGFDRLLQDVSAPAAVAYLWGLGDRSPEALSGAVTSSTLGALHLVKAMARAGWAQPPALWM
VTESAVAATPTDAVEGFAQASLWGFGRAVAIEHTEFMCRMVDLEPGSESLERLFLLMAQPPQENVLALRGGRILGARLVR
PGKPPERAAPVRIRPDGVYLVTGGLGALGLETAEWLVGAGARHLLLVGRSEPTDAANARLAALTARGVGVTVARADVSRQ
EDVQRLVASVSERGLSLRGIIHTAGVLEDGVILHQDAERFSRVFAPKVQGALNLHRATAGMPLDLFVMYSSAASLVGVAG
QSNYVAANSVLDALAHHRNRLGLPALSINWGRWAGAGMAAKSADRPEASDAASLSPEVALQVFEQLLEQGAVQVGVVPFS
VSSLEAGPSPGHGPLFSELMLREQARSAAASRMHELMEELKRADGERRRALLTRYVQSRLGPLLGFAPDHEVLQKRISLN
EMGLDSLRAVELKNRIGRELGVDLLMARFIDGTTLDGIVDALSTQLELKELLARAPAAEAAADIEELTV

Sequences:

>Translated_1829_residues
MAKLSTRISELPVVKLAYLASQLRSKKELLAAEPIAVVGMSCRFPGGGDLPETFWELLAEGRDATREVPASRWDVDAFYD
PTPGVPGKMYTRRGAFIDGVDLFDPGFFGITPRDAKGMDPQQRLLLEECWRALERAGIPPAGLTGSRTGIFLGLMHNDYN
LLGIAENMEFHSASLNYPSVAAGRISHTLGLQGPAVSVDTACSSSAVAIHLACQSLRNDESDLALAAGANLNLSPVTVMV
ECQNRMLAADGRCKTFDASADGFGRGEGCGVVVLKRLSDALAHGDAILGVIRGSAVTHDGRSSGMMVPNGRSQERVIRAA
LDSCGVEPDQVGYIEAHGTGTLLGDPIEMEALRSVFGRKGARGEPLYVGSVKTNIGHLEAAAGIAGLIKVLLALQNEAIP
AHLNFERPNPNIRWDDLPVTIPTATRPWLRGDKRRIAGVSSFGFSGTNVHMVVEEAPVLARPRVDAERPAHVLTLSAKSE
AALEALMEAQERALPEDPAALGDWCYTANTGRSQFEHRAAVSGATAAELRANLTRLREEKLRPAREPLRGTESPRPVFLF
TGQGALRPGVGRELFETQPVFRAAVERCSKALEGLLDCSLEALLFGESSAMLLEDTRHAQPALVALEYALAELWGAWGVT
PAALIGHSLGEYAAAAVAGVFSIEEALRLVVTRARLIGELLGPGAMLAVSAPLDTVNRAIAPHAGSVSLAAVNGPDDVVI
SGTPDAITEVEQALSSQGIQTKRLRMSYAFHSTQMEPVLKPFAEAFQGLTLSAPRIPLVSTLEGRRVGDEVSRPEYWCRQ
ILEPVAFAKALEASREDGHRTYLELGPAPILAGIGRRTFQSEELCWLPSLRPSTGETAQLLSSVAELYMRGFDVDWAAFD
APFERRPRCLPTHPFQRERYWMDLQSPENRRGYAARDDAARGDAHSLPGTPLSLAGAKETRFAARLSRHEPAFIEEHRVL
GNPVLPAACYVEMALGAAHHATSGGKPLELTAIELERALVFAEGQSQDVQTVLTPEEQGSRFEIFGQATGTADRNWARLA
QGRITEGRMNPEHVALESELLQAFPRQGSVSAHYDMMARGGLEYGPSFRGIDALRFGGEGCLAHVRLPDALVIGLGDYWL
HPLLLDACFQTAAAAFTDGGAQVAGEGQGRIPVAIERLRWFKRPGSSIWVHARTGARTSLSEGLASADLRILDEDGTVVA
EVEGLLLKQVDRRAFQAAFSGAMQELLFELAWREQPAPSARDQVASQSGPWLLLVDSDRVADEVRTLARQRAWICVVATP
GASYERVDANHYRLNPHDAAGFDRLLQDVSAPAAVAYLWGLGDRSPEALSGAVTSSTLGALHLVKAMARAGWAQPPALWM
VTESAVAATPTDAVEGFAQASLWGFGRAVAIEHTEFMCRMVDLEPGSESLERLFLLMAQPPQENVLALRGGRILGARLVR
PGKPPERAAPVRIRPDGVYLVTGGLGALGLETAEWLVGAGARHLLLVGRSEPTDAANARLAALTARGVGVTVARADVSRQ
EDVQRLVASVSERGLSLRGIIHTAGVLEDGVILHQDAERFSRVFAPKVQGALNLHRATAGMPLDLFVMYSSAASLVGVAG
QSNYVAANSVLDALAHHRNRLGLPALSINWGRWAGAGMAAKSADRPEASDAASLSPEVALQVFEQLLEQGAVQVGVVPFS
VSSLEAGPSPGHGPLFSELMLREQARSAAASRMHELMEELKRADGERRRALLTRYVQSRLGPLLGFAPDHEVLQKRISLN
EMGLDSLRAVELKNRIGRELGVDLLMARFIDGTTLDGIVDALSTQLELKELLARAPAAEAAADIEELTV
>Mature_1828_residues
AKLSTRISELPVVKLAYLASQLRSKKELLAAEPIAVVGMSCRFPGGGDLPETFWELLAEGRDATREVPASRWDVDAFYDP
TPGVPGKMYTRRGAFIDGVDLFDPGFFGITPRDAKGMDPQQRLLLEECWRALERAGIPPAGLTGSRTGIFLGLMHNDYNL
LGIAENMEFHSASLNYPSVAAGRISHTLGLQGPAVSVDTACSSSAVAIHLACQSLRNDESDLALAAGANLNLSPVTVMVE
CQNRMLAADGRCKTFDASADGFGRGEGCGVVVLKRLSDALAHGDAILGVIRGSAVTHDGRSSGMMVPNGRSQERVIRAAL
DSCGVEPDQVGYIEAHGTGTLLGDPIEMEALRSVFGRKGARGEPLYVGSVKTNIGHLEAAAGIAGLIKVLLALQNEAIPA
HLNFERPNPNIRWDDLPVTIPTATRPWLRGDKRRIAGVSSFGFSGTNVHMVVEEAPVLARPRVDAERPAHVLTLSAKSEA
ALEALMEAQERALPEDPAALGDWCYTANTGRSQFEHRAAVSGATAAELRANLTRLREEKLRPAREPLRGTESPRPVFLFT
GQGALRPGVGRELFETQPVFRAAVERCSKALEGLLDCSLEALLFGESSAMLLEDTRHAQPALVALEYALAELWGAWGVTP
AALIGHSLGEYAAAAVAGVFSIEEALRLVVTRARLIGELLGPGAMLAVSAPLDTVNRAIAPHAGSVSLAAVNGPDDVVIS
GTPDAITEVEQALSSQGIQTKRLRMSYAFHSTQMEPVLKPFAEAFQGLTLSAPRIPLVSTLEGRRVGDEVSRPEYWCRQI
LEPVAFAKALEASREDGHRTYLELGPAPILAGIGRRTFQSEELCWLPSLRPSTGETAQLLSSVAELYMRGFDVDWAAFDA
PFERRPRCLPTHPFQRERYWMDLQSPENRRGYAARDDAARGDAHSLPGTPLSLAGAKETRFAARLSRHEPAFIEEHRVLG
NPVLPAACYVEMALGAAHHATSGGKPLELTAIELERALVFAEGQSQDVQTVLTPEEQGSRFEIFGQATGTADRNWARLAQ
GRITEGRMNPEHVALESELLQAFPRQGSVSAHYDMMARGGLEYGPSFRGIDALRFGGEGCLAHVRLPDALVIGLGDYWLH
PLLLDACFQTAAAAFTDGGAQVAGEGQGRIPVAIERLRWFKRPGSSIWVHARTGARTSLSEGLASADLRILDEDGTVVAE
VEGLLLKQVDRRAFQAAFSGAMQELLFELAWREQPAPSARDQVASQSGPWLLLVDSDRVADEVRTLARQRAWICVVATPG
ASYERVDANHYRLNPHDAAGFDRLLQDVSAPAAVAYLWGLGDRSPEALSGAVTSSTLGALHLVKAMARAGWAQPPALWMV
TESAVAATPTDAVEGFAQASLWGFGRAVAIEHTEFMCRMVDLEPGSESLERLFLLMAQPPQENVLALRGGRILGARLVRP
GKPPERAAPVRIRPDGVYLVTGGLGALGLETAEWLVGAGARHLLLVGRSEPTDAANARLAALTARGVGVTVARADVSRQE
DVQRLVASVSERGLSLRGIIHTAGVLEDGVILHQDAERFSRVFAPKVQGALNLHRATAGMPLDLFVMYSSAASLVGVAGQ
SNYVAANSVLDALAHHRNRLGLPALSINWGRWAGAGMAAKSADRPEASDAASLSPEVALQVFEQLLEQGAVQVGVVPFSV
SSLEAGPSPGHGPLFSELMLREQARSAAASRMHELMEELKRADGERRRALLTRYVQSRLGPLLGFAPDHEVLQKRISLNE
MGLDSLRAVELKNRIGRELGVDLLMARFIDGTTLDGIVDALSTQLELKELLARAPAAEAAADIEELTV

Specific function: Catalyzes The Condensation Reaction Of Fatty Acid Synthesis By The Addition To An Acyl Acceptor Of Two Carbons From Malonyl-Acp. Has A Preference For Short Chain Acid Substrates And May Function To Supply The Octanoic Substrates For Lipoic Acid Biosynthe

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI41872631, Length=877, Percent_Identity=30.1026225769669, Blast_Score=300, Evalue=9e-81,
Organism=Homo sapiens, GI8923559, Length=279, Percent_Identity=30.1075268817204, Blast_Score=120, Evalue=1e-26,
Organism=Homo sapiens, GI239744023, Length=103, Percent_Identity=42.7184466019417, Blast_Score=95, Evalue=6e-19,
Organism=Homo sapiens, GI310129082, Length=103, Percent_Identity=42.7184466019417, Blast_Score=95, Evalue=6e-19,
Organism=Homo sapiens, GI310109937, Length=103, Percent_Identity=42.7184466019417, Blast_Score=95, Evalue=6e-19,
Organism=Homo sapiens, GI223972627, Length=146, Percent_Identity=33.5616438356164, Blast_Score=77, Evalue=1e-13,
Organism=Escherichia coli, GI1787337, Length=287, Percent_Identity=29.2682926829268, Blast_Score=111, Evalue=4e-25,
Organism=Escherichia coli, GI1787334, Length=292, Percent_Identity=29.7945205479452, Blast_Score=97, Evalue=9e-21,
Organism=Escherichia coli, GI1788663, Length=274, Percent_Identity=28.4671532846715, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI212642053, Length=867, Percent_Identity=29.8731257208766, Blast_Score=319, Evalue=9e-87,
Organism=Caenorhabditis elegans, GI17550940, Length=888, Percent_Identity=26.6891891891892, Blast_Score=260, Evalue=4e-69,
Organism=Caenorhabditis elegans, GI71983541, Length=286, Percent_Identity=29.7202797202797, Blast_Score=117, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71983535, Length=277, Percent_Identity=29.9638989169675, Blast_Score=113, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6320904, Length=279, Percent_Identity=29.3906810035842, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI19920632, Length=1102, Percent_Identity=26.7695099818512, Blast_Score=314, Evalue=4e-85,
Organism=Drosophila melanogaster, GI221330659, Length=1102, Percent_Identity=26.7695099818512, Blast_Score=314, Evalue=4e-85,
Organism=Drosophila melanogaster, GI24581345, Length=877, Percent_Identity=27.8221208665906, Blast_Score=296, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24644341, Length=362, Percent_Identity=31.4917127071823, Blast_Score=138, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR002198
- InterPro:   IPR015357
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR020806
- InterPro:   IPR015083
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00106 adh_short; PF00107 ADH_zinc_N; PF08990 Docking; PF09277 Erythro-docking; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF00550 PP-binding [H]

EC number: =2.3.1.94 [H]

Molecular weight: Translated: 196408; Mature: 196277

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50075 ACP_DOMAIN ; PS00626 RCC1_2 ; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLSTRISELPVVKLAYLASQLRSKKELLAAEPIAVVGMSCRFPGGGDLPETFWELLAE
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHC
GRDATREVPASRWDVDAFYDPTPGVPGKMYTRRGAFIDGVDLFDPGFFGITPRDAKGMDP
CCCHHHHCCCCCCCCCCEECCCCCCCCCCEECCCCEECCCCCCCCCCCCCCCCCCCCCCH
QQRLLLEECWRALERAGIPPAGLTGSRTGIFLGLMHNDYNLLGIAENMEFHSASLNYPSV
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCCCCC
AAGRISHTLGLQGPAVSVDTACSSSAVAIHLACQSLRNDESDLALAAGANLNLSPVTVMV
CHHHHHHHHCCCCCCEEECCCCCCCCEEHHEEHHHHCCCCCCEEEEECCCCCCCCEEEEE
ECQNRMLAADGRCKTFDASADGFGRGEGCGVVVLKRLSDALAHGDAILGVIRGSAVTHDG
EECCCEEECCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHEEEHCCCEECCCC
RSSGMMVPNGRSQERVIRAALDSCGVEPDQVGYIEAHGTGTLLGDPIEMEALRSVFGRKG
CCCCEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCC
ARGEPLYVGSVKTNIGHLEAAAGIAGLIKVLLALQNEAIPAHLNFERPNPNIRWDDLPVT
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEECCCCEE
IPTATRPWLRGDKRRIAGVSSFGFSGTNVHMVVEEAPVLARPRVDAERPAHVLTLSAKSE
ECCCCCCCCCCCCHHCCEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCHH
AALEALMEAQERALPEDPAALGDWCYTANTGRSQFEHRAAVSGATAAELRANLTRLREEK
HHHHHHHHHHHHCCCCCCCHHCCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LRPAREPLRGTESPRPVFLFTGQGALRPGVGRELFETQPVFRAAVERCSKALEGLLDCSL
CCHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
EALLFGESSAMLLEDTRHAQPALVALEYALAELWGAWGVTPAALIGHSLGEYAAAAVAGV
CEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
FSIEEALRLVVTRARLIGELLGPGAMLAVSAPLDTVNRAIAPHAGSVSLAAVNGPDDVVI
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCCCEEEEEECCCCCEEE
SGTPDAITEVEQALSSQGIQTKRLRMSYAFHSTQMEPVLKPFAEAFQGLTLSAPRIPLVS
ECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHH
TLEGRRVGDEVSRPEYWCRQILEPVAFAKALEASREDGHRTYLELGPAPILAGIGRRTFQ
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHCCCCCCC
SEELCWLPSLRPSTGETAQLLSSVAELYMRGFDVDWAAFDAPFERRPRCLPTHPFQRERY
CCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHCCCCCCCCCCCCCCE
WMDLQSPENRRGYAARDDAARGDAHSLPGTPLSLAGAKETRFAARLSRHEPAFIEEHRVL
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHCCCCCHHHHHHHC
GNPVLPAACYVEMALGAAHHATSGGKPLELTAIELERALVFAEGQSQDVQTVLTPEEQGS
CCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEHEEEEEEEEEECCCCCCCEEEECCCCCCC
RFEIFGQATGTADRNWARLAQGRITEGRMNPEHVALESELLQAFPRQGSVSAHYDMMARG
EEEEEECCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCC
GLEYGPSFRGIDALRFGGEGCLAHVRLPDALVIGLGDYWLHPLLLDACFQTAAAAFTDGG
CCCCCCCCCCCHHEEECCCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCC
AQVAGEGQGRIPVAIERLRWFKRPGSSIWVHARTGARTSLSEGLASADLRILDEDGTVVA
CEECCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHCCCCCCEEEECCCCCEEE
EVEGLLLKQVDRRAFQAAFSGAMQELLFELAWREQPAPSARDQVASQSGPWLLLVDSDRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEECCHHH
ADEVRTLARQRAWICVVATPGASYERVDANHYRLNPHDAAGFDRLLQDVSAPAAVAYLWG
HHHHHHHHHCCCEEEEEECCCCCCEECCCCCEECCCCCHHHHHHHHHHHCCCHHHHHHHC
LGDRSPEALSGAVTSSTLGALHLVKAMARAGWAQPPALWMVTESAVAATPTDAVEGFAQA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHH
SLWGFGRAVAIEHTEFMCRMVDLEPGSESLERLFLLMAQPPQENVLALRGGRILGARLVR
HHHCCCCEEEEEHHHHHEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCEEEEHEECC
PGKPPERAAPVRIRPDGVYLVTGGLGALGLETAEWLVGAGARHLLLVGRSEPTDAANARL
CCCCCCCCCCEEECCCCEEEEECCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCHHCCEE
AALTARGVGVTVARADVSRQEDVQRLVASVSERGLSLRGIIHTAGVLEDGVILHQDAERF
EEEEECCCEEEEEEHHCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCEEEECCHHHH
SRVFAPKVQGALNLHRATAGMPLDLFVMYSSAASLVGVAGQSNYVAANSVLDALAHHRNR
HHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHEEECCCCCEEHHHHHHHHHHHHHHC
LGLPALSINWGRWAGAGMAAKSADRPEASDAASLSPEVALQVFEQLLEQGAVQVGVVPFS
CCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEE
VSSLEAGPSPGHGPLFSELMLREQARSAAASRMHELMEELKRADGERRRALLTRYVQSRL
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
GPLLGFAPDHEVLQKRISLNEMGLDSLRAVELKNRIGRELGVDLLMARFIDGTTLDGIVD
HHHHCCCCCHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALSTQLELKELLARAPAAEAAADIEELTV
HHHHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
AKLSTRISELPVVKLAYLASQLRSKKELLAAEPIAVVGMSCRFPGGGDLPETFWELLAE
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHC
GRDATREVPASRWDVDAFYDPTPGVPGKMYTRRGAFIDGVDLFDPGFFGITPRDAKGMDP
CCCHHHHCCCCCCCCCCEECCCCCCCCCCEECCCCEECCCCCCCCCCCCCCCCCCCCCCH
QQRLLLEECWRALERAGIPPAGLTGSRTGIFLGLMHNDYNLLGIAENMEFHSASLNYPSV
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCCCCC
AAGRISHTLGLQGPAVSVDTACSSSAVAIHLACQSLRNDESDLALAAGANLNLSPVTVMV
CHHHHHHHHCCCCCCEEECCCCCCCCEEHHEEHHHHCCCCCCEEEEECCCCCCCCEEEEE
ECQNRMLAADGRCKTFDASADGFGRGEGCGVVVLKRLSDALAHGDAILGVIRGSAVTHDG
EECCCEEECCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHEEEHCCCEECCCC
RSSGMMVPNGRSQERVIRAALDSCGVEPDQVGYIEAHGTGTLLGDPIEMEALRSVFGRKG
CCCCEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCC
ARGEPLYVGSVKTNIGHLEAAAGIAGLIKVLLALQNEAIPAHLNFERPNPNIRWDDLPVT
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEECCCCEE
IPTATRPWLRGDKRRIAGVSSFGFSGTNVHMVVEEAPVLARPRVDAERPAHVLTLSAKSE
ECCCCCCCCCCCCHHCCEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCHH
AALEALMEAQERALPEDPAALGDWCYTANTGRSQFEHRAAVSGATAAELRANLTRLREEK
HHHHHHHHHHHHCCCCCCCHHCCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LRPAREPLRGTESPRPVFLFTGQGALRPGVGRELFETQPVFRAAVERCSKALEGLLDCSL
CCHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
EALLFGESSAMLLEDTRHAQPALVALEYALAELWGAWGVTPAALIGHSLGEYAAAAVAGV
CEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
FSIEEALRLVVTRARLIGELLGPGAMLAVSAPLDTVNRAIAPHAGSVSLAAVNGPDDVVI
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCCCEEEEEECCCCCEEE
SGTPDAITEVEQALSSQGIQTKRLRMSYAFHSTQMEPVLKPFAEAFQGLTLSAPRIPLVS
ECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHH
TLEGRRVGDEVSRPEYWCRQILEPVAFAKALEASREDGHRTYLELGPAPILAGIGRRTFQ
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHCCCCCCC
SEELCWLPSLRPSTGETAQLLSSVAELYMRGFDVDWAAFDAPFERRPRCLPTHPFQRERY
CCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHCCCCCCCCCCCCCCE
WMDLQSPENRRGYAARDDAARGDAHSLPGTPLSLAGAKETRFAARLSRHEPAFIEEHRVL
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHCCCCCHHHHHHHC
GNPVLPAACYVEMALGAAHHATSGGKPLELTAIELERALVFAEGQSQDVQTVLTPEEQGS
CCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEHEEEEEEEEEECCCCCCCEEEECCCCCCC
RFEIFGQATGTADRNWARLAQGRITEGRMNPEHVALESELLQAFPRQGSVSAHYDMMARG
EEEEEECCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCC
GLEYGPSFRGIDALRFGGEGCLAHVRLPDALVIGLGDYWLHPLLLDACFQTAAAAFTDGG
CCCCCCCCCCCHHEEECCCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCC
AQVAGEGQGRIPVAIERLRWFKRPGSSIWVHARTGARTSLSEGLASADLRILDEDGTVVA
CEECCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHCCCCCCEEEECCCCCEEE
EVEGLLLKQVDRRAFQAAFSGAMQELLFELAWREQPAPSARDQVASQSGPWLLLVDSDRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEECCHHH
ADEVRTLARQRAWICVVATPGASYERVDANHYRLNPHDAAGFDRLLQDVSAPAAVAYLWG
HHHHHHHHHCCCEEEEEECCCCCCEECCCCCEECCCCCHHHHHHHHHHHCCCHHHHHHHC
LGDRSPEALSGAVTSSTLGALHLVKAMARAGWAQPPALWMVTESAVAATPTDAVEGFAQA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHH
SLWGFGRAVAIEHTEFMCRMVDLEPGSESLERLFLLMAQPPQENVLALRGGRILGARLVR
HHHCCCCEEEEEHHHHHEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCEEEEHEECC
PGKPPERAAPVRIRPDGVYLVTGGLGALGLETAEWLVGAGARHLLLVGRSEPTDAANARL
CCCCCCCCCCEEECCCCEEEEECCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCHHCCEE
AALTARGVGVTVARADVSRQEDVQRLVASVSERGLSLRGIIHTAGVLEDGVILHQDAERF
EEEEECCCEEEEEEHHCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCEEEECCHHHH
SRVFAPKVQGALNLHRATAGMPLDLFVMYSSAASLVGVAGQSNYVAANSVLDALAHHRNR
HHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHEEECCCCCEEHHHHHHHHHHHHHHC
LGLPALSINWGRWAGAGMAAKSADRPEASDAASLSPEVALQVFEQLLEQGAVQVGVVPFS
CCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEE
VSSLEAGPSPGHGPLFSELMLREQARSAAASRMHELMEELKRADGERRRALLTRYVQSRL
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
GPLLGFAPDHEVLQKRISLNEMGLDSLRAVELKNRIGRELGVDLLMARFIDGTTLDGIVD
HHHHCCCCCHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALSTQLELKELLARAPAAEAAADIEELTV
HHHHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2024119; 1740151 [H]