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The map label for this gene is lgrC [H]

Identifier: 108761108

GI number: 108761108

Start: 5263436

End: 5267743

Strand: Reverse

Name: lgrC [H]

Synonym: MXAN_4296

Alternate gene names: 108761108

Gene position: 5267743-5263436 (Counterclockwise)

Preceding gene: 108762792

Following gene: 108759846

Centisome position: 57.64

GC content: 68.22

Gene sequence:

>4308_bases
ATGAATCTGGGGGAACTGCTCGCCGAGCTGAATCGGCGGGGCCTGGAAGTCCGGGTGGAAGGCGACGCGCTGAGGCTTCG
CGGACCGAAAGGCGCCGCCACCGCAGAGCTTCGGCAGGCACTGGCGGAACACAAACCCGAGTTGCTCGAACTCCTGCGTG
CCCATGACCGGGGGCAGGAGGAGGCGCCCATCGTCCCGGTTCAACGCACCGGGCCCGCGCCGCTCTCCTATGGGCAGACG
CGGCTGTGGTTCCTCGACCGCTTGGAGCCTGGGAGCACCGCCTACAACCTGATGCTGGCGTTGCAGGTCGAAGGGCACCT
CGACGTAGCCATCGTGAAGCGCTGCTTCACCGAGGTCATCCGCCGCCACGAGGTGCTGCGCACGCGGTATGCCGAGCACG
CGGGCGTCCCGGTCCAGATTGTCGACCCGGAGCCCCGGTTCGACTTCCGCGTGCTCGACGAGCGCGAGGTGCTGGCCTCC
GAACCCGCGGGCGTGGAGGCCTTCCTCCAGCGAGAGGGCAAGCGGCCCTTCGACCTGTCCACGGGCCCCGTGATGCGTGT
GCTCATCATCGAGCGGGGGCCCCAGGGGCAGTACCTCCAGCTCTGCTTGCACCACATCGCGGCGGACGTGTGGGCGCAGG
CCATCCTCGTCCGCGAAATCGTGACGTTATATGGCGCCTTCGCCAGCGGCCAACCTTCGCCGTTGCCGCCCCTGACGCTC
CAGTACTCCGACTTCGCTGTCTGGCAGCGGGAGTACCTCCAGGGCGAGGTTCGCCAGAAGCTGGTGGACTACTGGCGCAG
GAAGCTGGAGGGGGCGCCTCCGCTGCTCGAGCTCCCCACGGACCATCCTCGCCCCAAGGTGCAGTCGAACCGAGGCGGCG
AGGTCCGCTTCGAAGTGGGCCCCCAGCTCACCGCCGCCCTGAAGGCACAGAGCCACACGGCCCGCACCACGCCCTTCGTG
GGGATGCTGAGCGCGTTCTTCGTGCTCCTGCACCGCCTCACGGGGCGTGAGGACCTGGTCCTGGGCGCGAACTCCATCAA
CCGGACGCGTACGGAGCTGGAGCCGTTGGTGGGCTTCTTCGTGGACAACCTGGTGATGCGGGTGGACCTCGGTGGCGGCC
CGGGGTTCGCCACGGTGCTGGAGCGCGTGCGTGAGACGGTGCTCGATGCCTTCGCTCACCAGGACCTGCCCTTCGACCTG
CTCGTGGAGGAGCTGAGGCCCGCGCGCAGCCTGGGCTTCAACCCGCTGTTCCAGGTCGTGTTCGCCTGGGTCCGCGCTTC
CGGCGAGGCCCAGGACGAGACGGGCCTCCGCATGCGGCCGCTCGAGTTCGAGGCGGAATCATCGCGCTTCGACCTCAACC
TCTTCGTGGATGACCACGGCGACCGGCTGTCGGCGCGGATGGTGTTCAACCGCGACCTCTTCGAGCAGGGCACCATCCAG
CACTACGTGGACTGCTTCCAGGTGCTGCTCGAAGGGCTCGTGGCCGAGCCCCAGCGGCCGGTGGGCGAGCTGCCCGTGCT
CCCCGCGGATGTCCGCGAGCGCGTGCTCCGGCAGTGGAACGACACGGGGACGCCGGAGGCGGAAGGCGCGTGCCTCCATG
CGCTCATCGAGGCCCAGGCGCTGCGCACGCCGGATGCGGTGGCCATCGTCGTGGACGACTGGGAGCTGACCTACGGCGAG
CTCGACCAGCTCAGCGACCGGGTCGCAGCGTCACTCCAGGATTTGGACGTGGGACCGGAGGTGGTGGTCGGCGTCTACCT
GGACCGTTCGGCGGAGCTCATCGTGAGCCTGCTGGCGGTGATGAAGGCAGGGGGCGCGTTCCTCGCGCTCGACGCAGACG
AGCCCGTGGACCGGCTCCGCCACATCGTGGCGGATGCCCGGCCCCGGGTGGTGATTTCTTCCGCGAAGCTGTCCGAGCGC
CTCTGGGGCATGGGGGGCTTCGTCACGCTCCACGTGGACGAAGGCTACCGGGACATGCCCGCCGCGCCGGGCCAGCAGCT
CCGCCGCGACGTCCTCCCCGACCACCTGGCCTACATCCTCTACACGTCAGGCTCGACGGGCCGGCCCAAGGGCACGGAAA
TCACGCACCGGAGCATCGTCAACTACCTGCGCTGGAGCGTGGACGCCTACCGGCTTCGCGAAGGGACGGGGAGCCCGGTG
ATTGGCTCCGTCAGCTTCGACGGAACGCTGACGAGCCTCTTCGCGCCGCTCCTGGCGGGCCGCGCGCTGTTCCTCGTGCC
ACGTGGTCACGAAATCGACCAGTTGACGTCCCGGGACTACCCCGAGCAGGGCTTCAGCTTCATCAAGATGACGCCGTCGC
ACCTGCGGGCCTTCAACGGCCTGGGGCGCACGCGCGAGGTGCTCGGCCGCACCCATGCGGTGGTGCTGGGCGGGGAAGGG
CTGCACGGCGTGGATCTGGCCCCATGGCGGGAGCAGGGCCTCCCCACGCGCGTCATCAACGAGTACGGCCCCACCGAGGC
CGCGGTGGCGTGCTGCTTCGAGACACTGCTGCCGGATGGAACACCTCCCCCGGAGCGGGTGCCCATTGGCCGGCCCATCT
CGCACATGCGGTTGTACATCCTGGACCGGTACCTCCAGCCCGTGCCCGTTGGCGTACCCGGCGAGCTGTACATCGGCGGC
GTCGGACTGGCCCGAGGCTACCTGCGCCGGCCGGACCTGACGGCGGAGCGCTTCGTCCCCAACCCCTTCGACGGGGGCCT
GGAGGGCTCGCGGCTCTACCGCACGGGGGACCACGCCCGGTACCTCTCCGACGGCCGCATCGAATACCTGGGCCGCCAGG
ACGACCAGCTCAAGATTCGCGGTCACCGCGTCGAGACGGGAGAGGTGGAGGCCGCGCTGGGCCGCCATCCCGACGTCGTC
CAGGCCGCGGTGCTCCTGCAGCGCCTCCCGAGCGGGGCGCCGCGCCTGGTGGCCTACGTGCAGCCCCAGTCGATGGAGAA
CGGTGACCTGCGGGCCGAGCTGCGCAAGTCCCTGCGTGAGGTGTTGCCCGAGTACATGATGCCGGAGGTCATCGCGGTCC
TCCCGGAGCTGCCGCTGACGCCCAGCGGGAAGATTGACCGCAAGGCGCTCCCGCCCGTGGCGTCCGAGGCCCCCGTCGCC
AGCGCGCTGGCCCGCACGGAAGCGCGGACCGAGACGGAGCGGCAACTCCAGGCGCTGTTCGGTGAACTCCTGGGACTGAG
CTCCGTGGCGCCCACCGACAGCTTCTTCGAACTGGGAGGCCATTCGCTCCTCGCCGTCACGCTCATCTCGCGCATCTCCG
CGAAGCTGGACATCGAGGTGCCCCTCAACGAGGTGTTCGACCGGCCCTCCGTGGAGTCCCTGGCGCACTGGATTGACGAA
CACTCCAGCAAGGTCACCGCGCTGATTCGCCAGCTTCCCGCCTGTGTGGTGGCGCTGAAGCCCCTGGGACACAAACCGCC
GCTGTTCCTTGCCCCGCCGTCCGCTGGCAGTCCGGCCGTCTACGTCACCCTGGCCCGCCACCTGGACGCGGAGCAGCCCG
TGTTCGGCTTCCAGATGCCTGGCGTCATGGACGACCAACTGCCACCCGAGACCATCGAGGACACCGCCGCGCTGTATGTG
GCGGCCCTGCGGCAGGTCCAGCCGCGCGGGCCGTACCGGATCGCGGGCTGGTCCTACGGAGGACTCGTCGTCTGTGAAAT
GGCGCGGCAGCTCGAAGCGCTCGGGGAACAGGTGGCGCTGCTCGGCTTGATTGACGGCGCGGCGTTGGACCGGTTGTCCG
CGCACGACGGTACCCCGCAGGAGATTCCCGCGGGCTCCCAGCTCATCAAGGTGCTGGGGGAAGCCCAGATGCCGCGGGAC
TATGCCAGCCTGAGATTGATAGGCGAATGGATGGGAATCAGCCTGCCCGAGGCATGGGCAGACCTGCTTCGTCGGGATAC
AGATGGGCAGTATTCATACCTGTGGCGTTTCTTGCGAGACAGCGCGCTGACGGCCCGGAATTTCCTGGCAACACGCCGCT
CGGAGCAACTCTATACGTTCTCTTCGTATGGAGGCTCCGCCACACTTTTCAGGACGGGTCCGGTGACGATTGGAGGCGAT
CCGCTCGTCGACAGTGTGCGCAGATTCGCGCTCGCGGGGACGGAAGTGATACCGGTTCCGGGCAATCACATGACGCTCAT
CATGGATGAACGGAATGTCGCCGTGCTTGCAATTGAAATACAGAAATGTCTGGATAGGGCTTTGACGCTCCCGCCAATCG
CAGAAATGTCTCGGGCGGAAATGCCAGCAAAGGGGCTGGCTGCGCAGCTCCTCATGGAGGTCATGTAA

Upstream 100 bases:

>100_bases
ACGGGATTGTGGATGCGCTGAGCACCCAGCTCGAGCTCAAGGAGCTGCTCGCGCGTGCTCCCGCGGCGGAGGCCGCAGCC
GACATCGAGGAGTTGACGGT

Downstream 100 bases:

>100_bases
TGCCGCACCGAGTCCTTGCAATGGATGGTACGTCTATTTCCGGCGGTGAAGGGTATGTCACCGCGGGCTTGCTCAAGTCG
TTGAAGGAGACGCTGACCAG

Product: non-ribosomal peptide synthetase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1435; Mature: 1435

Protein sequence:

>1435_residues
MNLGELLAELNRRGLEVRVEGDALRLRGPKGAATAELRQALAEHKPELLELLRAHDRGQEEAPIVPVQRTGPAPLSYGQT
RLWFLDRLEPGSTAYNLMLALQVEGHLDVAIVKRCFTEVIRRHEVLRTRYAEHAGVPVQIVDPEPRFDFRVLDEREVLAS
EPAGVEAFLQREGKRPFDLSTGPVMRVLIIERGPQGQYLQLCLHHIAADVWAQAILVREIVTLYGAFASGQPSPLPPLTL
QYSDFAVWQREYLQGEVRQKLVDYWRRKLEGAPPLLELPTDHPRPKVQSNRGGEVRFEVGPQLTAALKAQSHTARTTPFV
GMLSAFFVLLHRLTGREDLVLGANSINRTRTELEPLVGFFVDNLVMRVDLGGGPGFATVLERVRETVLDAFAHQDLPFDL
LVEELRPARSLGFNPLFQVVFAWVRASGEAQDETGLRMRPLEFEAESSRFDLNLFVDDHGDRLSARMVFNRDLFEQGTIQ
HYVDCFQVLLEGLVAEPQRPVGELPVLPADVRERVLRQWNDTGTPEAEGACLHALIEAQALRTPDAVAIVVDDWELTYGE
LDQLSDRVAASLQDLDVGPEVVVGVYLDRSAELIVSLLAVMKAGGAFLALDADEPVDRLRHIVADARPRVVISSAKLSER
LWGMGGFVTLHVDEGYRDMPAAPGQQLRRDVLPDHLAYILYTSGSTGRPKGTEITHRSIVNYLRWSVDAYRLREGTGSPV
IGSVSFDGTLTSLFAPLLAGRALFLVPRGHEIDQLTSRDYPEQGFSFIKMTPSHLRAFNGLGRTREVLGRTHAVVLGGEG
LHGVDLAPWREQGLPTRVINEYGPTEAAVACCFETLLPDGTPPPERVPIGRPISHMRLYILDRYLQPVPVGVPGELYIGG
VGLARGYLRRPDLTAERFVPNPFDGGLEGSRLYRTGDHARYLSDGRIEYLGRQDDQLKIRGHRVETGEVEAALGRHPDVV
QAAVLLQRLPSGAPRLVAYVQPQSMENGDLRAELRKSLREVLPEYMMPEVIAVLPELPLTPSGKIDRKALPPVASEAPVA
SALARTEARTETERQLQALFGELLGLSSVAPTDSFFELGGHSLLAVTLISRISAKLDIEVPLNEVFDRPSVESLAHWIDE
HSSKVTALIRQLPACVVALKPLGHKPPLFLAPPSAGSPAVYVTLARHLDAEQPVFGFQMPGVMDDQLPPETIEDTAALYV
AALRQVQPRGPYRIAGWSYGGLVVCEMARQLEALGEQVALLGLIDGAALDRLSAHDGTPQEIPAGSQLIKVLGEAQMPRD
YASLRLIGEWMGISLPEAWADLLRRDTDGQYSYLWRFLRDSALTARNFLATRRSEQLYTFSSYGGSATLFRTGPVTIGGD
PLVDSVRRFALAGTEVIPVPGNHMTLIMDERNVAVLAIEIQKCLDRALTLPPIAEMSRAEMPAKGLAAQLLMEVM

Sequences:

>Translated_1435_residues
MNLGELLAELNRRGLEVRVEGDALRLRGPKGAATAELRQALAEHKPELLELLRAHDRGQEEAPIVPVQRTGPAPLSYGQT
RLWFLDRLEPGSTAYNLMLALQVEGHLDVAIVKRCFTEVIRRHEVLRTRYAEHAGVPVQIVDPEPRFDFRVLDEREVLAS
EPAGVEAFLQREGKRPFDLSTGPVMRVLIIERGPQGQYLQLCLHHIAADVWAQAILVREIVTLYGAFASGQPSPLPPLTL
QYSDFAVWQREYLQGEVRQKLVDYWRRKLEGAPPLLELPTDHPRPKVQSNRGGEVRFEVGPQLTAALKAQSHTARTTPFV
GMLSAFFVLLHRLTGREDLVLGANSINRTRTELEPLVGFFVDNLVMRVDLGGGPGFATVLERVRETVLDAFAHQDLPFDL
LVEELRPARSLGFNPLFQVVFAWVRASGEAQDETGLRMRPLEFEAESSRFDLNLFVDDHGDRLSARMVFNRDLFEQGTIQ
HYVDCFQVLLEGLVAEPQRPVGELPVLPADVRERVLRQWNDTGTPEAEGACLHALIEAQALRTPDAVAIVVDDWELTYGE
LDQLSDRVAASLQDLDVGPEVVVGVYLDRSAELIVSLLAVMKAGGAFLALDADEPVDRLRHIVADARPRVVISSAKLSER
LWGMGGFVTLHVDEGYRDMPAAPGQQLRRDVLPDHLAYILYTSGSTGRPKGTEITHRSIVNYLRWSVDAYRLREGTGSPV
IGSVSFDGTLTSLFAPLLAGRALFLVPRGHEIDQLTSRDYPEQGFSFIKMTPSHLRAFNGLGRTREVLGRTHAVVLGGEG
LHGVDLAPWREQGLPTRVINEYGPTEAAVACCFETLLPDGTPPPERVPIGRPISHMRLYILDRYLQPVPVGVPGELYIGG
VGLARGYLRRPDLTAERFVPNPFDGGLEGSRLYRTGDHARYLSDGRIEYLGRQDDQLKIRGHRVETGEVEAALGRHPDVV
QAAVLLQRLPSGAPRLVAYVQPQSMENGDLRAELRKSLREVLPEYMMPEVIAVLPELPLTPSGKIDRKALPPVASEAPVA
SALARTEARTETERQLQALFGELLGLSSVAPTDSFFELGGHSLLAVTLISRISAKLDIEVPLNEVFDRPSVESLAHWIDE
HSSKVTALIRQLPACVVALKPLGHKPPLFLAPPSAGSPAVYVTLARHLDAEQPVFGFQMPGVMDDQLPPETIEDTAALYV
AALRQVQPRGPYRIAGWSYGGLVVCEMARQLEALGEQVALLGLIDGAALDRLSAHDGTPQEIPAGSQLIKVLGEAQMPRD
YASLRLIGEWMGISLPEAWADLLRRDTDGQYSYLWRFLRDSALTARNFLATRRSEQLYTFSSYGGSATLFRTGPVTIGGD
PLVDSVRRFALAGTEVIPVPGNHMTLIMDERNVAVLAIEIQKCLDRALTLPPIAEMSRAEMPAKGLAAQLLMEVM
>Mature_1435_residues
MNLGELLAELNRRGLEVRVEGDALRLRGPKGAATAELRQALAEHKPELLELLRAHDRGQEEAPIVPVQRTGPAPLSYGQT
RLWFLDRLEPGSTAYNLMLALQVEGHLDVAIVKRCFTEVIRRHEVLRTRYAEHAGVPVQIVDPEPRFDFRVLDEREVLAS
EPAGVEAFLQREGKRPFDLSTGPVMRVLIIERGPQGQYLQLCLHHIAADVWAQAILVREIVTLYGAFASGQPSPLPPLTL
QYSDFAVWQREYLQGEVRQKLVDYWRRKLEGAPPLLELPTDHPRPKVQSNRGGEVRFEVGPQLTAALKAQSHTARTTPFV
GMLSAFFVLLHRLTGREDLVLGANSINRTRTELEPLVGFFVDNLVMRVDLGGGPGFATVLERVRETVLDAFAHQDLPFDL
LVEELRPARSLGFNPLFQVVFAWVRASGEAQDETGLRMRPLEFEAESSRFDLNLFVDDHGDRLSARMVFNRDLFEQGTIQ
HYVDCFQVLLEGLVAEPQRPVGELPVLPADVRERVLRQWNDTGTPEAEGACLHALIEAQALRTPDAVAIVVDDWELTYGE
LDQLSDRVAASLQDLDVGPEVVVGVYLDRSAELIVSLLAVMKAGGAFLALDADEPVDRLRHIVADARPRVVISSAKLSER
LWGMGGFVTLHVDEGYRDMPAAPGQQLRRDVLPDHLAYILYTSGSTGRPKGTEITHRSIVNYLRWSVDAYRLREGTGSPV
IGSVSFDGTLTSLFAPLLAGRALFLVPRGHEIDQLTSRDYPEQGFSFIKMTPSHLRAFNGLGRTREVLGRTHAVVLGGEG
LHGVDLAPWREQGLPTRVINEYGPTEAAVACCFETLLPDGTPPPERVPIGRPISHMRLYILDRYLQPVPVGVPGELYIGG
VGLARGYLRRPDLTAERFVPNPFDGGLEGSRLYRTGDHARYLSDGRIEYLGRQDDQLKIRGHRVETGEVEAALGRHPDVV
QAAVLLQRLPSGAPRLVAYVQPQSMENGDLRAELRKSLREVLPEYMMPEVIAVLPELPLTPSGKIDRKALPPVASEAPVA
SALARTEARTETERQLQALFGELLGLSSVAPTDSFFELGGHSLLAVTLISRISAKLDIEVPLNEVFDRPSVESLAHWIDE
HSSKVTALIRQLPACVVALKPLGHKPPLFLAPPSAGSPAVYVTLARHLDAEQPVFGFQMPGVMDDQLPPETIEDTAALYV
AALRQVQPRGPYRIAGWSYGGLVVCEMARQLEALGEQVALLGLIDGAALDRLSAHDGTPQEIPAGSQLIKVLGEAQMPRD
YASLRLIGEWMGISLPEAWADLLRRDTDGQYSYLWRFLRDSALTARNFLATRRSEQLYTFSSYGGSATLFRTGPVTIGGD
PLVDSVRRFALAGTEVIPVPGNHMTLIMDERNVAVLAIEIQKCLDRALTLPPIAEMSRAEMPAKGLAAQLLMEVM

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI115511026, Length=586, Percent_Identity=24.7440273037543, Blast_Score=89, Evalue=5e-17,
Organism=Homo sapiens, GI42544132, Length=376, Percent_Identity=26.8617021276596, Blast_Score=84, Evalue=9e-16,
Organism=Homo sapiens, GI157311624, Length=372, Percent_Identity=26.3440860215054, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI157311622, Length=372, Percent_Identity=26.3440860215054, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI58082049, Length=372, Percent_Identity=27.9569892473118, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI38505220, Length=367, Percent_Identity=25.6130790190736, Blast_Score=81, Evalue=7e-15,
Organism=Homo sapiens, GI122937307, Length=366, Percent_Identity=25.4098360655738, Blast_Score=75, Evalue=6e-13,
Organism=Homo sapiens, GI41872631, Length=87, Percent_Identity=44.8275862068966, Blast_Score=72, Evalue=4e-12,
Organism=Escherichia coli, GI1786801, Length=1211, Percent_Identity=30.9661436829067, Blast_Score=412, Evalue=1e-115,
Organism=Escherichia coli, GI1790505, Length=592, Percent_Identity=25, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI1789201, Length=379, Percent_Identity=29.8153034300792, Blast_Score=78, Evalue=3e-15,
Organism=Escherichia coli, GI1788107, Length=375, Percent_Identity=25.3333333333333, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1786810, Length=175, Percent_Identity=30.8571428571429, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17550940, Length=585, Percent_Identity=23.7606837606838, Blast_Score=120, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17556356, Length=1075, Percent_Identity=22.1395348837209, Blast_Score=117, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71982997, Length=381, Percent_Identity=28.6089238845144, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71983001, Length=382, Percent_Identity=28.7958115183246, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560308, Length=219, Percent_Identity=27.8538812785388, Blast_Score=74, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319591, Length=956, Percent_Identity=25, Blast_Score=251, Evalue=4e-67,
Organism=Drosophila melanogaster, GI24648676, Length=619, Percent_Identity=30.048465266559, Blast_Score=220, Evalue=7e-57,
Organism=Drosophila melanogaster, GI62472339, Length=376, Percent_Identity=27.1276595744681, Blast_Score=89, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24667959, Length=376, Percent_Identity=27.1276595744681, Blast_Score=89, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24667955, Length=376, Percent_Identity=27.1276595744681, Blast_Score=89, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24581924, Length=378, Percent_Identity=26.4550264550265, Blast_Score=82, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 158444; Mature: 158444

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLGELLAELNRRGLEVRVEGDALRLRGPKGAATAELRQALAEHKPELLELLRAHDRGQE
CCHHHHHHHHCCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCC
EAPIVPVQRTGPAPLSYGQTRLWFLDRLEPGSTAYNLMLALQVEGHLDVAIVKRCFTEVI
CCCEEEECCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHH
RRHEVLRTRYAEHAGVPVQIVDPEPRFDFRVLDEREVLASEPAGVEAFLQREGKRPFDLS
HHHHHHHHHHHHHCCCCEEEECCCCCCCEEECCCHHHHHCCCCCHHHHHHHCCCCCCCCC
TGPVMRVLIIERGPQGQYLQLCLHHIAADVWAQAILVREIVTLYGAFASGQPSPLPPLTL
CCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
QYSDFAVWQREYLQGEVRQKLVDYWRRKLEGAPPLLELPTDHPRPKVQSNRGGEVRFEVG
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCEEEEECC
PQLTAALKAQSHTARTTPFVGMLSAFFVLLHRLTGREDLVLGANSINRTRTELEPLVGFF
CCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHH
VDNLVMRVDLGGGPGFATVLERVRETVLDAFAHQDLPFDLLVEELRPARSLGFNPLFQVV
HHCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHH
FAWVRASGEAQDETGLRMRPLEFEAESSRFDLNLFVDDHGDRLSARMVFNRDLFEQGTIQ
HHHHHCCCCCCCCCCCEECCCCCCCCCCEEEEEEEEECCCCCEEEEEECCHHHHHCCCHH
HYVDCFQVLLEGLVAEPQRPVGELPVLPADVRERVLRQWNDTGTPEAEGACLHALIEAQA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LRTPDAVAIVVDDWELTYGELDQLSDRVAASLQDLDVGPEVVVGVYLDRSAELIVSLLAV
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHH
MKAGGAFLALDADEPVDRLRHIVADARPRVVISSAKLSERLWGMGGFVTLHVDEGYRDMP
HHCCCCEEEECCCCHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCEEEEEECCCCCCCC
AAPGQQLRRDVLPDHLAYILYTSGSTGRPKGTEITHRSIVNYLRWSVDAYRLREGTGSPV
CCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCE
IGSVSFDGTLTSLFAPLLAGRALFLVPRGHEIDQLTSRDYPEQGFSFIKMTPSHLRAFNG
EEEEECCCHHHHHHHHHHCCCEEEEEECCCCHHHHHCCCCCHHCCEEEEECHHHHHHHHC
LGRTREVLGRTHAVVLGGEGLHGVDLAPWREQGLPTRVINEYGPTEAAVACCFETLLPDG
CCHHHHHHCCCEEEEECCCCCCCCCCCCHHHCCCCHHHHHHCCCHHHHHHHHHHHHCCCC
TPPPERVPIGRPISHMRLYILDRYLQPVPVGVPGELYIGGVGLARGYLRRPDLTAERFVP
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHCCCCCCHHHCCC
NPFDGGLEGSRLYRTGDHARYLSDGRIEYLGRQDDQLKIRGHRVETGEVEAALGRHPDVV
CCCCCCCCCCEEEECCCCHHHCCCCCEEECCCCCCEEEEECEEECCCCHHHHHCCCCHHH
QAAVLLQRLPSGAPRLVAYVQPQSMENGDLRAELRKSLREVLPEYMMPEVIAVLPELPLT
HHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PSGKIDRKALPPVASEAPVASALARTEARTETERQLQALFGELLGLSSVAPTDSFFELGG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCC
HSLLAVTLISRISAKLDIEVPLNEVFDRPSVESLAHWIDEHSSKVTALIRQLPACVVALK
CHHHHHHHHHHHCCCEEEEECHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLGHKPPLFLAPPSAGSPAVYVTLARHLDAEQPVFGFQMPGVMDDQLPPETIEDTAALYV
CCCCCCCEEEECCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
AALRQVQPRGPYRIAGWSYGGLVVCEMARQLEALGEQVALLGLIDGAALDRLSAHDGTPQ
HHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHEEHHHHHCCHHHHHHHCCCCCCC
EIPAGSQLIKVLGEAQMPRDYASLRLIGEWMGISLPEAWADLLRRDTDGQYSYLWRFLRD
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHH
SALTARNFLATRRSEQLYTFSSYGGSATLFRTGPVTIGGDPLVDSVRRFALAGTEVIPVP
HHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCEEECCCHHHHHHHHHHHCCCEEEECC
GNHMTLIMDERNVAVLAIEIQKCLDRALTLPPIAEMSRAEMPAKGLAAQLLMEVM
CCEEEEEEECCCEEEEEEEHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MNLGELLAELNRRGLEVRVEGDALRLRGPKGAATAELRQALAEHKPELLELLRAHDRGQE
CCHHHHHHHHCCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCC
EAPIVPVQRTGPAPLSYGQTRLWFLDRLEPGSTAYNLMLALQVEGHLDVAIVKRCFTEVI
CCCEEEECCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHH
RRHEVLRTRYAEHAGVPVQIVDPEPRFDFRVLDEREVLASEPAGVEAFLQREGKRPFDLS
HHHHHHHHHHHHHCCCCEEEECCCCCCCEEECCCHHHHHCCCCCHHHHHHHCCCCCCCCC
TGPVMRVLIIERGPQGQYLQLCLHHIAADVWAQAILVREIVTLYGAFASGQPSPLPPLTL
CCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
QYSDFAVWQREYLQGEVRQKLVDYWRRKLEGAPPLLELPTDHPRPKVQSNRGGEVRFEVG
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCEEEEECC
PQLTAALKAQSHTARTTPFVGMLSAFFVLLHRLTGREDLVLGANSINRTRTELEPLVGFF
CCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHH
VDNLVMRVDLGGGPGFATVLERVRETVLDAFAHQDLPFDLLVEELRPARSLGFNPLFQVV
HHCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHH
FAWVRASGEAQDETGLRMRPLEFEAESSRFDLNLFVDDHGDRLSARMVFNRDLFEQGTIQ
HHHHHCCCCCCCCCCCEECCCCCCCCCCEEEEEEEEECCCCCEEEEEECCHHHHHCCCHH
HYVDCFQVLLEGLVAEPQRPVGELPVLPADVRERVLRQWNDTGTPEAEGACLHALIEAQA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LRTPDAVAIVVDDWELTYGELDQLSDRVAASLQDLDVGPEVVVGVYLDRSAELIVSLLAV
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHH
MKAGGAFLALDADEPVDRLRHIVADARPRVVISSAKLSERLWGMGGFVTLHVDEGYRDMP
HHCCCCEEEECCCCHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCEEEEEECCCCCCCC
AAPGQQLRRDVLPDHLAYILYTSGSTGRPKGTEITHRSIVNYLRWSVDAYRLREGTGSPV
CCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCE
IGSVSFDGTLTSLFAPLLAGRALFLVPRGHEIDQLTSRDYPEQGFSFIKMTPSHLRAFNG
EEEEECCCHHHHHHHHHHCCCEEEEEECCCCHHHHHCCCCCHHCCEEEEECHHHHHHHHC
LGRTREVLGRTHAVVLGGEGLHGVDLAPWREQGLPTRVINEYGPTEAAVACCFETLLPDG
CCHHHHHHCCCEEEEECCCCCCCCCCCCHHHCCCCHHHHHHCCCHHHHHHHHHHHHCCCC
TPPPERVPIGRPISHMRLYILDRYLQPVPVGVPGELYIGGVGLARGYLRRPDLTAERFVP
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHCCCCCCHHHCCC
NPFDGGLEGSRLYRTGDHARYLSDGRIEYLGRQDDQLKIRGHRVETGEVEAALGRHPDVV
CCCCCCCCCCEEEECCCCHHHCCCCCEEECCCCCCEEEEECEEECCCCHHHHHCCCCHHH
QAAVLLQRLPSGAPRLVAYVQPQSMENGDLRAELRKSLREVLPEYMMPEVIAVLPELPLT
HHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PSGKIDRKALPPVASEAPVASALARTEARTETERQLQALFGELLGLSSVAPTDSFFELGG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCC
HSLLAVTLISRISAKLDIEVPLNEVFDRPSVESLAHWIDEHSSKVTALIRQLPACVVALK
CHHHHHHHHHHHCCCEEEEECHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLGHKPPLFLAPPSAGSPAVYVTLARHLDAEQPVFGFQMPGVMDDQLPPETIEDTAALYV
CCCCCCCEEEECCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
AALRQVQPRGPYRIAGWSYGGLVVCEMARQLEALGEQVALLGLIDGAALDRLSAHDGTPQ
HHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHEEHHHHHCCHHHHHHHCCCCCCC
EIPAGSQLIKVLGEAQMPRDYASLRLIGEWMGISLPEAWADLLRRDTDGQYSYLWRFLRD
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHH
SALTARNFLATRRSEQLYTFSSYGGSATLFRTGPVTIGGDPLVDSVRRFALAGTEVIPVP
HHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCEEECCCHHHHHHHHHHHCCCEEEECC
GNHMTLIMDERNVAVLAIEIQKCLDRALTLPPIAEMSRAEMPAKGLAAQLLMEVM
CCEEEEEEECCCEEEEEEEHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA