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The map label for this gene is gcp [H]

Identifier: 108762785

GI number: 108762785

Start: 2383728

End: 2384723

Strand: Direct

Name: gcp [H]

Synonym: MXAN_2051

Alternate gene names: 108762785

Gene position: 2383728-2384723 (Clockwise)

Preceding gene: 108763462

Following gene: 108758752

Centisome position: 26.08

GC content: 70.38

Gene sequence:

>996_bases
TTGCTCGTCCTAGGACTGGAAACCTCGTGTGATGAGACTGCCGCCGCCGTCGTGGAGGACGGCCGCCGCGCGTTGTCGGA
TGTCGTCTCCACGCAGGTGGACATCCACCGGCGGTGGGGTGGGGTGGTGCCGGAGCTGGCCAGCCGCAACCACATCGTCC
AGGTGCTGCCCGTCGTCCACGAGGCGCTGACGCGGGCGAACAAGACGCTCGACGACGTGGACCTCATCGCCGTCACGTCC
GGCCCCGGACTCATCGGCGCGCTGCTGGTGGGAGTGCAGGTGGCCAAGGGCTTGAGCCTGGCGACGGGCAAGCCCTTCGT
GGGCGCCAACCACCTGGAGGGCCACCTGCTGGCCATCCGGCTGTTGGAGGTGGCGCCGGAGCCGCCGTTCCTTGGGCTCG
TCGTTTCCGGCGGGCACACCAGCCTCTACGAGGTGCAGGCCTACGGGCAGTACCGGCTGGTGGGCAGCACGCGCGACGAC
GCGGCCGGCGAGGCATATGACAAGACCGCTCGCATCCTCGGCCTGCCGTATCCGGGTGGGCAGCCCATCGACCAGTTGGC
GCAGCAGGGGAACCCGGAGGCCATCCGCTTCCCGCGCGCGCTGCCGGGCGACAACTTCGACGTGTCCTTCTCCGGGTTGA
AGACGGCGGTGCTGCACCACGTGCAGAAGCACGGCGTGCCGCAGGGGCAGGCGCTGGCGGATTTGTGCGCGTCCTTCCAG
GAGGCCGTGGCGGACGTGCTGTCGAAGAAGCTGGTGGCCGCCGCGCGCCGGTTGGGCCACAAGCAGTTGGTGCTGTGCGG
CGGCGTCGCCGCGAACTCGCGGCTGCGGGCACTGTGTCAGGCGCGAGCCGAGGAGCGGGGGTTGAACATGTTCCTGCCCC
CGGTGCGGCTGTGCACGGACAATGGCGCCATGATTGCGGTGGCGGGGTATGAGGCGTACCGCCGCGGCCTGCGCGGAGAT
TTCCGCCTCGCCGCCGACCCGGCCTGGCGCATGTAG

Upstream 100 bases:

>100_bases
GGGTCTTCCGCCGAAGAGGTCCGCACGTTGCTCAGGGGGCTGGGCAACTGAGCGGGGACGGCCCCACTTCCATCATTGGC
CCCCTGAGAAGTGAGCTGCC

Downstream 100 bases:

>100_bases
AGGGGAGCAGACGGGTGGAATCGCCTAGAGACATCCTCAAGCGGCATGGCCTGCGCGCCAAGTACAGCTGGGGACAGAAC
TTCCTCGGAGACGAGGACGC

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MLVLGLETSCDETAAAVVEDGRRALSDVVSTQVDIHRRWGGVVPELASRNHIVQVLPVVHEALTRANKTLDDVDLIAVTS
GPGLIGALLVGVQVAKGLSLATGKPFVGANHLEGHLLAIRLLEVAPEPPFLGLVVSGGHTSLYEVQAYGQYRLVGSTRDD
AAGEAYDKTARILGLPYPGGQPIDQLAQQGNPEAIRFPRALPGDNFDVSFSGLKTAVLHHVQKHGVPQGQALADLCASFQ
EAVADVLSKKLVAAARRLGHKQLVLCGGVAANSRLRALCQARAEERGLNMFLPPVRLCTDNGAMIAVAGYEAYRRGLRGD
FRLAADPAWRM

Sequences:

>Translated_331_residues
MLVLGLETSCDETAAAVVEDGRRALSDVVSTQVDIHRRWGGVVPELASRNHIVQVLPVVHEALTRANKTLDDVDLIAVTS
GPGLIGALLVGVQVAKGLSLATGKPFVGANHLEGHLLAIRLLEVAPEPPFLGLVVSGGHTSLYEVQAYGQYRLVGSTRDD
AAGEAYDKTARILGLPYPGGQPIDQLAQQGNPEAIRFPRALPGDNFDVSFSGLKTAVLHHVQKHGVPQGQALADLCASFQ
EAVADVLSKKLVAAARRLGHKQLVLCGGVAANSRLRALCQARAEERGLNMFLPPVRLCTDNGAMIAVAGYEAYRRGLRGD
FRLAADPAWRM
>Mature_331_residues
MLVLGLETSCDETAAAVVEDGRRALSDVVSTQVDIHRRWGGVVPELASRNHIVQVLPVVHEALTRANKTLDDVDLIAVTS
GPGLIGALLVGVQVAKGLSLATGKPFVGANHLEGHLLAIRLLEVAPEPPFLGLVVSGGHTSLYEVQAYGQYRLVGSTRDD
AAGEAYDKTARILGLPYPGGQPIDQLAQQGNPEAIRFPRALPGDNFDVSFSGLKTAVLHHVQKHGVPQGQALADLCASFQ
EAVADVLSKKLVAAARRLGHKQLVLCGGVAANSRLRALCQARAEERGLNMFLPPVRLCTDNGAMIAVAGYEAYRRGLRGD
FRLAADPAWRM

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=343, Percent_Identity=37.3177842565598, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI8923380, Length=323, Percent_Identity=37.4613003095975, Blast_Score=159, Evalue=3e-39,
Organism=Escherichia coli, GI1789445, Length=332, Percent_Identity=45.1807228915663, Blast_Score=278, Evalue=4e-76,
Organism=Caenorhabditis elegans, GI71995670, Length=325, Percent_Identity=35.3846153846154, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17557464, Length=322, Percent_Identity=31.055900621118, Blast_Score=141, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6320099, Length=358, Percent_Identity=30.7262569832402, Blast_Score=145, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6322891, Length=303, Percent_Identity=31.6831683168317, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI20129063, Length=338, Percent_Identity=34.9112426035503, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI21357207, Length=334, Percent_Identity=35.6287425149701, Blast_Score=161, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 35202; Mature: 35202

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVLGLETSCDETAAAVVEDGRRALSDVVSTQVDIHRRWGGVVPELASRNHIVQVLPVVH
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHH
EALTRANKTLDDVDLIAVTSGPGLIGALLVGVQVAKGLSLATGKPFVGANHLEGHLLAIR
HHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHH
LLEVAPEPPFLGLVVSGGHTSLYEVQAYGQYRLVGSTRDDAAGEAYDKTARILGLPYPGG
HHHHCCCCCEEEEEEECCCCEEEEEEECCEEEEECCCCCCCCCHHHHCCHHEEECCCCCC
QPIDQLAQQGNPEAIRFPRALPGDNFDVSFSGLKTAVLHHVQKHGVPQGQALADLCASFQ
CCHHHHHHCCCCCEEECCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
EAVADVLSKKLVAAARRLGHKQLVLCGGVAANSRLRALCQARAEERGLNMFLPPVRLCTD
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEECCCCEEECC
NGAMIAVAGYEAYRRGLRGDFRLAADPAWRM
CCCEEEEECHHHHHCCCCCCEEEECCCCCCC
>Mature Secondary Structure
MLVLGLETSCDETAAAVVEDGRRALSDVVSTQVDIHRRWGGVVPELASRNHIVQVLPVVH
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHH
EALTRANKTLDDVDLIAVTSGPGLIGALLVGVQVAKGLSLATGKPFVGANHLEGHLLAIR
HHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHH
LLEVAPEPPFLGLVVSGGHTSLYEVQAYGQYRLVGSTRDDAAGEAYDKTARILGLPYPGG
HHHHCCCCCEEEEEEECCCCEEEEEEECCEEEEECCCCCCCCCHHHHCCHHEEECCCCCC
QPIDQLAQQGNPEAIRFPRALPGDNFDVSFSGLKTAVLHHVQKHGVPQGQALADLCASFQ
CCHHHHHHCCCCCEEECCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
EAVADVLSKKLVAAARRLGHKQLVLCGGVAANSRLRALCQARAEERGLNMFLPPVRLCTD
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEECCCCEEECC
NGAMIAVAGYEAYRRGLRGDFRLAADPAWRM
CCCEEEEECHHHHHCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA