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The map label for this gene is cheB3

Identifier: 108762780

GI number: 108762780

Start: 6425472

End: 6426530

Strand: Reverse

Name: cheB3

Synonym: MXAN_5145

Alternate gene names: 108762780

Gene position: 6426530-6425472 (Counterclockwise)

Preceding gene: 108761228

Following gene: 108758057

Centisome position: 70.31

GC content: 70.54

Gene sequence:

>1059_bases
ATGGGCAAGAAAGTGTCGGTGCTGGTGGTCGATGACTCCCTCATCTGCCGACAGCTCATCTGCGAGGCGCTGAGCAAGGA
CCCCGATATCGAAGTCGTGGGCACCTGCGCGGACGGCAAGCAGGCCGTGGAGATGACCAAGGAGCTGCGTCCCCACGTCA
TCACCATGGACGTGGACATGCCCGTCATGGACGGGCTCACGGCCACCGAGCACATCATGGCCGAGTGCCCCACGCCCATC
CTGGTGCTCACGGCGGACCCGCGCTCACAGGCGCCGGAGCTGACGTACCGCGCGCTGGAGCTGGGCGCGCTCGCTCTGCA
AATCAAGCCCGCGATCGACGCCGGGCCGGACGCGTGGAACCTGGTTCGCGAAATCCGGCTGCTGTCCTCGGTGCGTGTCA
TCCGCCACCTGCGCCGGCCCCAGCGCGGCCCGCTGTTGCCGCCCCGGGTGGCCACGTCGGTGCTGCCGGCGGTGTCCATG
GGCGTGGTGGTGGTGGCGGCGAGCACGGGCGGGCCCCAGGTGCTCTTCAAGATGCTGTCGGAGCTGCCTGCGGACTTTCC
GGCGCCCATCGTCATCGTCCAGCACATCAACGCCGCCTTCGCGGAGTCCCTGGCGGGGTGGCTGGCCGGGGCCAGCAAGT
TGAAGGTCCGGCTGGCGCAGGACGGAGAGCCGCTGATGCCGGGGCACGTCCTCATCGCTCCGCCGGGGCAGCACACCGTC
ATCCCCTTCCGGGGACGCGTGGGGATCAAGCTGGGCGTGGAGCGGGATGGGCACATGCCGTCCGGCACGGTGCTGCTGGA
GAGCGCCGCCCGCACCTATGGCCGGCGCGCGGTGGGCCTGGTGCTGACGGGCATGGGGGCGGATGGCGCGGATGGCCTGC
TGGCCATCAAGCAGGCGGGCGGACTGGCGGTGGCGCAGAACGAGGAGTCCTGCGTGGTGTTCGGCATGCCGGGCGCGGCG
GTGGAGCGCAAGGCGGTGGACCACCTCATCCACGGTGACGAAGTCGCGGCGACGTTGGTGCGACTGGCGCGGGGAGAGTC
CCTCTCGGTGGGGCGCTGA

Upstream 100 bases:

>100_bases
CGCCCAGGGCAACCTGGTGGATGTGGTGCGGCGACTGCTGGGCTGACAAGCCCCTGCATTGGCTATACTCCCGGGCTCGC
GCACGGGGTATGGACAGGGC

Downstream 100 bases:

>100_bases
GCCCGGGTGACTGACGGCGCGCCATGGTCCGGAGTGCGCGCCTTCCTGTCGGCGCGGACGGGGATGGCCCTGAGTGGCCC
TCAGGTCCGCCGGCTGGATG

Product: protein-glutamate methylesterase CheB3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MGKKVSVLVVDDSLICRQLICEALSKDPDIEVVGTCADGKQAVEMTKELRPHVITMDVDMPVMDGLTATEHIMAECPTPI
LVLTADPRSQAPELTYRALELGALALQIKPAIDAGPDAWNLVREIRLLSSVRVIRHLRRPQRGPLLPPRVATSVLPAVSM
GVVVVAASTGGPQVLFKMLSELPADFPAPIVIVQHINAAFAESLAGWLAGASKLKVRLAQDGEPLMPGHVLIAPPGQHTV
IPFRGRVGIKLGVERDGHMPSGTVLLESAARTYGRRAVGLVLTGMGADGADGLLAIKQAGGLAVAQNEESCVVFGMPGAA
VERKAVDHLIHGDEVAATLVRLARGESLSVGR

Sequences:

>Translated_352_residues
MGKKVSVLVVDDSLICRQLICEALSKDPDIEVVGTCADGKQAVEMTKELRPHVITMDVDMPVMDGLTATEHIMAECPTPI
LVLTADPRSQAPELTYRALELGALALQIKPAIDAGPDAWNLVREIRLLSSVRVIRHLRRPQRGPLLPPRVATSVLPAVSM
GVVVVAASTGGPQVLFKMLSELPADFPAPIVIVQHINAAFAESLAGWLAGASKLKVRLAQDGEPLMPGHVLIAPPGQHTV
IPFRGRVGIKLGVERDGHMPSGTVLLESAARTYGRRAVGLVLTGMGADGADGLLAIKQAGGLAVAQNEESCVVFGMPGAA
VERKAVDHLIHGDEVAATLVRLARGESLSVGR
>Mature_351_residues
GKKVSVLVVDDSLICRQLICEALSKDPDIEVVGTCADGKQAVEMTKELRPHVITMDVDMPVMDGLTATEHIMAECPTPIL
VLTADPRSQAPELTYRALELGALALQIKPAIDAGPDAWNLVREIRLLSSVRVIRHLRRPQRGPLLPPRVATSVLPAVSMG
VVVVAASTGGPQVLFKMLSELPADFPAPIVIVQHINAAFAESLAGWLAGASKLKVRLAQDGEPLMPGHVLIAPPGQHTVI
PFRGRVGIKLGVERDGHMPSGTVLLESAARTYGRRAVGLVLTGMGADGADGLLAIKQAGGLAVAQNEESCVVFGMPGAAV
ERKAVDHLIHGDEVAATLVRLARGESLSVGR

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1788192, Length=360, Percent_Identity=36.6666666666667, Blast_Score=199, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CHEB2_MYXXD (Q1D225)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_633298.1
- ProteinModelPortal:   Q1D225
- SMR:   Q1D225
- STRING:   Q1D225
- GeneID:   4106533
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_5145
- TIGR:   MXAN_5145
- eggNOG:   COG2201
- HOGENOM:   HBG705324
- OMA:   ATEHIMA
- PhylomeDB:   Q1D225
- BioCyc:   MXAN246197:MXAN_5145-MONOMER
- GO:   GO:0005737
- GO:   GO:0006935
- HAMAP:   MF_00099
- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789
- Gene3D:   G3DSA:3.40.50.180
- PIRSF:   PIRSF000876
- SMART:   SM00448

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg; SSF52738 Chemotax_RR_pGlu_Me-esterase; SSF52172 CheY_like

EC number: =3.1.1.61

Molecular weight: Translated: 37119; Mature: 36988

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS50122 CHEB; PS50110 RESPONSE_REGULATORY

Important sites: ACT_SITE 168-168 ACT_SITE 195-195 ACT_SITE 288-288

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKKVSVLVVDDSLICRQLICEALSKDPDIEVVGTCADGKQAVEMTKELRPHVITMDVDM
CCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEECCC
PVMDGLTATEHIMAECPTPILVLTADPRSQAPELTYRALELGALALQIKPAIDAGPDAWN
HHHCCCCHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHCEEEEEEECCCCCCCCHHH
LVREIRLLSSVRVIRHLRRPQRGPLLPPRVATSVLPAVSMGVVVVAASTGGPQVLFKMLS
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
ELPADFPAPIVIVQHINAAFAESLAGWLAGASKLKVRLAQDGEPLMPGHVLIAPPGQHTV
HCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEECCCCCEE
IPFRGRVGIKLGVERDGHMPSGTVLLESAARTYGRRAVGLVLTGMGADGADGLLAIKQAG
EEECCCEEEEEECCCCCCCCCCCEEHHHHHHHHCCEEEEEEEEECCCCCCCCEEEEECCC
GLAVAQNEESCVVFGMPGAAVERKAVDHLIHGDEVAATLVRLARGESLSVGR
CEEEEECCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
GKKVSVLVVDDSLICRQLICEALSKDPDIEVVGTCADGKQAVEMTKELRPHVITMDVDM
CCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEECCC
PVMDGLTATEHIMAECPTPILVLTADPRSQAPELTYRALELGALALQIKPAIDAGPDAWN
HHHCCCCHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHCEEEEEEECCCCCCCCHHH
LVREIRLLSSVRVIRHLRRPQRGPLLPPRVATSVLPAVSMGVVVVAASTGGPQVLFKMLS
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
ELPADFPAPIVIVQHINAAFAESLAGWLAGASKLKVRLAQDGEPLMPGHVLIAPPGQHTV
HCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEECCCCCEE
IPFRGRVGIKLGVERDGHMPSGTVLLESAARTYGRRAVGLVLTGMGADGADGLLAIKQAG
EEECCCEEEEEECCCCCCCCCCCEEHHHHHHHHCCEEEEEEEEECCCCCCCCEEEEECCC
GLAVAQNEESCVVFGMPGAAVERKAVDHLIHGDEVAATLVRLARGESLSVGR
CEEEEECCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA