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The map label for this gene is cheA3 [H]

Identifier: 108761228

GI number: 108761228

Start: 6429145

End: 6431541

Strand: Reverse

Name: cheA3 [H]

Synonym: MXAN_5147

Alternate gene names: 108761228

Gene position: 6431541-6429145 (Counterclockwise)

Preceding gene: 108761207

Following gene: 108762780

Centisome position: 70.37

GC content: 71.92

Gene sequence:

>2397_bases
GTGACCCCGAGCGAGCGCCTGCTCAGGCAGTTCCGGGACCTGGTGACGGTGCGCCTGGAGCGCATCACCCGGTCCTTGAT
GGAACTGGAGTCTGGCGCCAGCGCGGAGGCGGGGCGGGGCGTGCTGCGAGAGCTGCACGGCTTGAAGGGCGAAGCCCGGA
TGATGGGCTTCGATGACGTCAACGTGCTGGTGCACGAAATGGAGGAGCTGGTCCGCTGCACTGAGCCCTTGCGCTACGCG
CTCTCACCCGCGTCCACGGATGCGTTGCTGACCACGGCGGACGCCGTGCTCGTGTTCTCCGGGACGCAGGCCGCCGATGA
GCCGCCGCCCGCGGTGGAGCGGCTCGTCGCGTGGTTGCAGGAGTGCGTCCGCTCCGAGTCGGTGCGGCTGCCGCCTGGAC
GTCTCGTGCCCGCAGAAGGAGCCCCCGCGACTTCGGAGGCCGCTGGCCGCGTAGGAGCCCAAGGTGGTCCCCACTCCGCC
GTGCAGACGAACCCGGGGGCTTCTCCGGGGCGGCTGTTGACGATCCCCGTCGCGGAGGGGAGCCGGCCTCACGTGCCTTC
ACCGGGCCGGAGCGCGATGCCGAGCTTCGTCTCTCCGCAAGCCTCTGGCGCCGAGGCGTCCTCCGGTGCGGGAGCCCGGG
CGGCCTCCTCGGCTCCGACGGTGCAGGGTTCCAACGGCCTCACGGCGCCCCGGCAGCCCGAGTCACGTCCGGACACTGCG
GTGCGCATCGGCGTGGAGAGCCTGGACCTGCTCACCAGTGCCGTCACCAACCTCACGCAAGTGGCGCGTCGCCGGGAGCT
GGCCAATGCCCGACGCCTGGCCCTGGCCCGTGAGCTGAGCCAGCTTGCCCGCGAGGCGGAAGACCTGGGGCCCGCGGGCG
CCGCGTTGGCGGCACGGTTGGGCTCGGCCAAGGAGATGGCCGCGGTCCTCCACCGCGAGTCGAAGCTGCTTTCCAATGCG
GAGCTGCGCGACCTGGGCATGTTGGTGGAGGAGGTGCAGACGCTGCGCATGCTGCCGCTCTCCGTCCTCTTCGAGCCTTA
CCCCCGCATGGTGCGCGACCTGTCCCGCGCGCTGGGCAAGGAGGTGGAGCTGGTCGTCGACGGCGAGGACACTCGCGCCG
ACCGCGCCGTCGTGGAGGCGCTTCGCGAGCCGTTGATGCACCTGGTCCGCAACGCCCTGGACCACGGACTGGAGACGCGG
GTGGACCGCGTCACGGCGGACAAGAAGCCGCGTGGCTGTCTCACGCTGCGTGCCGCTCGAGAGGGCAACCGCATCAACCT
CCGTGTCGAGGACGACGGCATGGGCGTGGACCCCGTCCAACTCCGCAAGGTGGCCGTGCGCAGGGGGCTGTTCGACGAGA
GCGCCGCCAACGCCCTGTCGGACGCCGCGGCCCGCGAGCTCATCTTCCTGCCGGGCTTCACCTCGCGGGACGTCGTCACC
GACCTGTCGGGCCGGGGCGTGGGGTTGGACGCGGTGCGCACCTCCATCCAGGCCCTGGGCGGTGACGTCGGGGTGGAGTC
TGCGCCGGGCTGGGGCACCATCTTCGAGCTGCGCGTCCCCGTCTCCCTCACCGTGGCCCCGCTGCTCTTCATCCAGGTGG
GGACGGAGACGCTGGCCCTGAGCGCCACCCATGTCTCGCGGGCGCTGAAGGTGGACTCGGCGGAGCAATGCGAGGTGGCC
GGCCGCCCGTCGCTCCTGGTGGAAGGCCGGGTCCTGCCGCTGGCCCCGCTGTCGTCACTGTTGGGGCTGGAGCCTCCGCG
GCCCGCTCGCGAGGGTGAGCTGGCCCTGGTGGTGAAGAGCCAGAGCGGCGCGGCGGCGCTGGTGGTGGACCGCGTCCTGG
AGGAGCGGGTCCAGGCCATCCTCCCCTTGAAGGGCATCCTGGGTCGCTTCGGCCACCTCACCGGGGCCACGTCCCTGGCG
GATGGGCGCCTGGCCATGGTGCTCTCGGCGGCCTTCCTCACCGCCAGCGCCCACCAAGGCAATGCCTTGCCGCGTCCACC
CCCATCGGTGGAGCCCGGTCCCGAGGCCCGGCGGCGCCGCATTCTGGTGGTGGACGACTCGCCCCTCACCCGGGAGCTCA
TCGCCAACCTGCTGGAGGCGGTGGGGTACGACACTGTCATCGCCTCGGACGGCGCGGAGGCCCTGGAGGTCCTGGAGTCT
CATCCCGTGGACCTGGTCGTCACGGACCTGGAGATGCCGGGGGTGAACGGCCTGGAGCTGGCCCGGCGCCTGAAGGGGCA
CCCCGTCCATTCGAGGCTCCCGGTGGTCATCCTCACTACCCGTGGGGGGGAGGAGGACCGGCGGCGGGGGTTGGCGGCCG
GGGTGGACGGCTACATCACCAAGGGCGACCTGGTGCGCCAGGACCTGGTGGATGTGGTGCGGCGACTGCTGGGCTGA

Upstream 100 bases:

>100_bases
TGACGACGGCGAACACGGACCTGCTCGTGCTCGCCAGGGACCTGCAGGGCGTGGTGGAGCGCTTCCAGATTGGCCAGGAG
CCGCTGGGGGAGGAGGGCGG

Downstream 100 bases:

>100_bases
CAGGCCCCTGAATTGGCTGTGCCCCGCCGGCGTATCGGCGGGATAGAAGCCATGTGGGTTGAGGGGGAGGGCTGGAGCGG
AGGAGGCGAGGAGGGCCGCT

Product: sensor histidine kinase/response regulator CheA3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 798; Mature: 797

Protein sequence:

>798_residues
MTPSERLLRQFRDLVTVRLERITRSLMELESGASAEAGRGVLRELHGLKGEARMMGFDDVNVLVHEMEELVRCTEPLRYA
LSPASTDALLTTADAVLVFSGTQAADEPPPAVERLVAWLQECVRSESVRLPPGRLVPAEGAPATSEAAGRVGAQGGPHSA
VQTNPGASPGRLLTIPVAEGSRPHVPSPGRSAMPSFVSPQASGAEASSGAGARAASSAPTVQGSNGLTAPRQPESRPDTA
VRIGVESLDLLTSAVTNLTQVARRRELANARRLALARELSQLAREAEDLGPAGAALAARLGSAKEMAAVLHRESKLLSNA
ELRDLGMLVEEVQTLRMLPLSVLFEPYPRMVRDLSRALGKEVELVVDGEDTRADRAVVEALREPLMHLVRNALDHGLETR
VDRVTADKKPRGCLTLRAAREGNRINLRVEDDGMGVDPVQLRKVAVRRGLFDESAANALSDAAARELIFLPGFTSRDVVT
DLSGRGVGLDAVRTSIQALGGDVGVESAPGWGTIFELRVPVSLTVAPLLFIQVGTETLALSATHVSRALKVDSAEQCEVA
GRPSLLVEGRVLPLAPLSSLLGLEPPRPAREGELALVVKSQSGAAALVVDRVLEERVQAILPLKGILGRFGHLTGATSLA
DGRLAMVLSAAFLTASAHQGNALPRPPPSVEPGPEARRRRILVVDDSPLTRELIANLLEAVGYDTVIASDGAEALEVLES
HPVDLVVTDLEMPGVNGLELARRLKGHPVHSRLPVVILTTRGGEEDRRRGLAAGVDGYITKGDLVRQDLVDVVRRLLG

Sequences:

>Translated_798_residues
MTPSERLLRQFRDLVTVRLERITRSLMELESGASAEAGRGVLRELHGLKGEARMMGFDDVNVLVHEMEELVRCTEPLRYA
LSPASTDALLTTADAVLVFSGTQAADEPPPAVERLVAWLQECVRSESVRLPPGRLVPAEGAPATSEAAGRVGAQGGPHSA
VQTNPGASPGRLLTIPVAEGSRPHVPSPGRSAMPSFVSPQASGAEASSGAGARAASSAPTVQGSNGLTAPRQPESRPDTA
VRIGVESLDLLTSAVTNLTQVARRRELANARRLALARELSQLAREAEDLGPAGAALAARLGSAKEMAAVLHRESKLLSNA
ELRDLGMLVEEVQTLRMLPLSVLFEPYPRMVRDLSRALGKEVELVVDGEDTRADRAVVEALREPLMHLVRNALDHGLETR
VDRVTADKKPRGCLTLRAAREGNRINLRVEDDGMGVDPVQLRKVAVRRGLFDESAANALSDAAARELIFLPGFTSRDVVT
DLSGRGVGLDAVRTSIQALGGDVGVESAPGWGTIFELRVPVSLTVAPLLFIQVGTETLALSATHVSRALKVDSAEQCEVA
GRPSLLVEGRVLPLAPLSSLLGLEPPRPAREGELALVVKSQSGAAALVVDRVLEERVQAILPLKGILGRFGHLTGATSLA
DGRLAMVLSAAFLTASAHQGNALPRPPPSVEPGPEARRRRILVVDDSPLTRELIANLLEAVGYDTVIASDGAEALEVLES
HPVDLVVTDLEMPGVNGLELARRLKGHPVHSRLPVVILTTRGGEEDRRRGLAAGVDGYITKGDLVRQDLVDVVRRLLG
>Mature_797_residues
TPSERLLRQFRDLVTVRLERITRSLMELESGASAEAGRGVLRELHGLKGEARMMGFDDVNVLVHEMEELVRCTEPLRYAL
SPASTDALLTTADAVLVFSGTQAADEPPPAVERLVAWLQECVRSESVRLPPGRLVPAEGAPATSEAAGRVGAQGGPHSAV
QTNPGASPGRLLTIPVAEGSRPHVPSPGRSAMPSFVSPQASGAEASSGAGARAASSAPTVQGSNGLTAPRQPESRPDTAV
RIGVESLDLLTSAVTNLTQVARRRELANARRLALARELSQLAREAEDLGPAGAALAARLGSAKEMAAVLHRESKLLSNAE
LRDLGMLVEEVQTLRMLPLSVLFEPYPRMVRDLSRALGKEVELVVDGEDTRADRAVVEALREPLMHLVRNALDHGLETRV
DRVTADKKPRGCLTLRAAREGNRINLRVEDDGMGVDPVQLRKVAVRRGLFDESAANALSDAAARELIFLPGFTSRDVVTD
LSGRGVGLDAVRTSIQALGGDVGVESAPGWGTIFELRVPVSLTVAPLLFIQVGTETLALSATHVSRALKVDSAEQCEVAG
RPSLLVEGRVLPLAPLSSLLGLEPPRPAREGELALVVKSQSGAAALVVDRVLEERVQAILPLKGILGRFGHLTGATSLAD
GRLAMVLSAAFLTASAHQGNALPRPPPSVEPGPEARRRRILVVDDSPLTRELIANLLEAVGYDTVIASDGAEALEVLESH
PVDLVVTDLEMPGVNGLELARRLKGHPVHSRLPVVILTTRGGEEDRRRGLAAGVDGYITKGDLVRQDLVDVVRRLLG

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=446, Percent_Identity=31.8385650224215, Blast_Score=188, Evalue=1e-48,
Organism=Escherichia coli, GI145693157, Length=400, Percent_Identity=27, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1786599, Length=103, Percent_Identity=43.6893203883495, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790863, Length=101, Percent_Identity=41.5841584158416, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788394, Length=102, Percent_Identity=37.2549019607843, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788713, Length=96, Percent_Identity=37.5, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1788191, Length=103, Percent_Identity=34.9514563106796, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1787375, Length=102, Percent_Identity=36.2745098039216, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84759; Mature: 84628

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSERLLRQFRDLVTVRLERITRSLMELESGASAEAGRGVLRELHGLKGEARMMGFDDV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEECCCHH
NVLVHEMEELVRCTEPLRYALSPASTDALLTTADAVLVFSGTQAADEPPPAVERLVAWLQ
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEECCEEEEEECCCCCCCCCHHHHHHHHHHH
ECVRSESVRLPPGRLVPAEGAPATSEAAGRVGAQGGPHSAVQTNPGASPGRLLTIPVAEG
HHHHCCCCCCCCCCEECCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
SRPHVPSPGRSAMPSFVSPQASGAEASSGAGARAASSAPTVQGSNGLTAPRQPESRPDTA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
VRIGVESLDLLTSAVTNLTQVARRRELANARRLALARELSQLAREAEDLGPAGAALAARL
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GSAKEMAAVLHRESKLLSNAELRDLGMLVEEVQTLRMLPLSVLFEPYPRMVRDLSRALGK
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCC
EVELVVDGEDTRADRAVVEALREPLMHLVRNALDHGLETRVDRVTADKKPRGCLTLRAAR
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEECC
EGNRINLRVEDDGMGVDPVQLRKVAVRRGLFDESAANALSDAAARELIFLPGFTSRDVVT
CCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEECCCCCCCHHH
DLSGRGVGLDAVRTSIQALGGDVGVESAPGWGTIFELRVPVSLTVAPLLFIQVGTETLAL
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHEECCHHHEE
SATHVSRALKVDSAEQCEVAGRPSLLVEGRVLPLAPLSSLLGLEPPRPAREGELALVVKS
EHHHHHHHHCCCCHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEEC
QSGAAALVVDRVLEERVQAILPLKGILGRFGHLTGATSLADGRLAMVLSAAFLTASAHQG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCC
NALPRPPPSVEPGPEARRRRILVVDDSPLTRELIANLLEAVGYDTVIASDGAEALEVLES
CCCCCCCCCCCCCCHHHCCEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHC
HPVDLVVTDLEMPGVNGLELARRLKGHPVHSRLPVVILTTRGGEEDRRRGLAAGVDGYIT
CCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHCCCCCCCCCCCC
KGDLVRQDLVDVVRRLLG
CHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TPSERLLRQFRDLVTVRLERITRSLMELESGASAEAGRGVLRELHGLKGEARMMGFDDV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEECCCHH
NVLVHEMEELVRCTEPLRYALSPASTDALLTTADAVLVFSGTQAADEPPPAVERLVAWLQ
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEECCEEEEEECCCCCCCCCHHHHHHHHHHH
ECVRSESVRLPPGRLVPAEGAPATSEAAGRVGAQGGPHSAVQTNPGASPGRLLTIPVAEG
HHHHCCCCCCCCCCEECCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
SRPHVPSPGRSAMPSFVSPQASGAEASSGAGARAASSAPTVQGSNGLTAPRQPESRPDTA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
VRIGVESLDLLTSAVTNLTQVARRRELANARRLALARELSQLAREAEDLGPAGAALAARL
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GSAKEMAAVLHRESKLLSNAELRDLGMLVEEVQTLRMLPLSVLFEPYPRMVRDLSRALGK
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCC
EVELVVDGEDTRADRAVVEALREPLMHLVRNALDHGLETRVDRVTADKKPRGCLTLRAAR
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEECC
EGNRINLRVEDDGMGVDPVQLRKVAVRRGLFDESAANALSDAAARELIFLPGFTSRDVVT
CCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEECCCCCCCHHH
DLSGRGVGLDAVRTSIQALGGDVGVESAPGWGTIFELRVPVSLTVAPLLFIQVGTETLAL
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHEECCHHHEE
SATHVSRALKVDSAEQCEVAGRPSLLVEGRVLPLAPLSSLLGLEPPRPAREGELALVVKS
EHHHHHHHHCCCCHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEEC
QSGAAALVVDRVLEERVQAILPLKGILGRFGHLTGATSLADGRLAMVLSAAFLTASAHQG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCC
NALPRPPPSVEPGPEARRRRILVVDDSPLTRELIANLLEAVGYDTVIASDGAEALEVLES
CCCCCCCCCCCCCCHHHCCEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHC
HPVDLVVTDLEMPGVNGLELARRLKGHPVHSRLPVVILTTRGGEEDRRRGLAAGVDGYIT
CCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHCCCCCCCCCCCC
KGDLVRQDLVDVVRRLLG
CHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]