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The map label for this gene is ygdL [H]

Identifier: 108762547

GI number: 108762547

Start: 2314754

End: 2315620

Strand: Reverse

Name: ygdL [H]

Synonym: MXAN_1979

Alternate gene names: 108762547

Gene position: 2315620-2314754 (Counterclockwise)

Preceding gene: 108760274

Following gene: 108757570

Centisome position: 25.34

GC content: 69.78

Gene sequence:

>867_bases
ATGAATCCGCAGCCGCTCCCCGCCCCTGCCCCTGAGACTCCGCCCACCGCCCCGGACTCGCTCGCCCGTCCCTTCAAGCT
CTCCCGGCGCTTCGACCGGACCGGCCGCCTGCTGGGCGACTCCGCGATGGAGCGGCTGGCCAACGCGCGCGTGGTGGTGT
TCGGCCTGGGCGGCGTGGGCAGCTTCGCGGCGGAGGGCCTGGTGCGCAGCGGCATTGGCCACCTGACGCTGGTGGACCAT
GACGACGTGTGCGTCACCAACACCAACCGCCAGCTCCACGCGACGGTGAAGGCCGTGGGCAAGCCCAAGGCGGAGCTGAT
GGCGCAGCGCTGCCAGGAAATCAATCCGGCGGCGAAGGTGGAGGCGGTGCGCGAGTTCTACCGCGCGGACGTGGCCGAGC
AGATGCTCCAGCCGGGCCAGTACGACTTCGTCGTGGACGCCATCGACAACGTGAAGGCGAAGCTGCACCTGCTGCACCGC
TGCGTGACGCTGGGCGTGCCGGTGGTCAGCTCCATGGGCGCCGCGGGCCGGTTGGACCCCACCGCCATCCGCGTGGAGGA
CCTGTCCGAGACGCACATGGACCCCTTCGCCAAGGACATCCGCAAGCTGCTCAAGCGCAAGTACGCGGTGGAGACGGACA
AGCACACGGGAATCACCGCCGTGTACTCCATCGAAGCGCGGCGGCTGCCGGTGACGCTCCAGTACGACGACGCCACCGAC
GGCTTCCTGTGCGTGTGCCCGCAGGACAACGAGTTCCACACCTGCGACCACCGCACGCAGATTGACGGCAGCGTGGCCTT
CGTCACGTCCTGCTTCGGGATGAACGCGGCGGGCGTGGTGGTGCGGCGGCTCGCGTCGGCGCGCTAG

Upstream 100 bases:

>100_bases
GAGGTCGCCCGGCAGACGACCGAGAATGCCCGCCGCTTCTTCCGGGAAGCTTTCCCTGCACCTTCGCGGTAGGCGAGCGG
TCGCGTTATAGAGGACCGCC

Downstream 100 bases:

>100_bases
GCGCTCAGACCACCTGCTGCGGTTGGGGCGCTTCGGGCGCGGCGCCCTCGCGTCCGCAGGGACGGCGGAAGACGCACCGT
GCGCAGGACGTCAGCGACTC

Product: ThiF domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MNPQPLPAPAPETPPTAPDSLARPFKLSRRFDRTGRLLGDSAMERLANARVVVFGLGGVGSFAAEGLVRSGIGHLTLVDH
DDVCVTNTNRQLHATVKAVGKPKAELMAQRCQEINPAAKVEAVREFYRADVAEQMLQPGQYDFVVDAIDNVKAKLHLLHR
CVTLGVPVVSSMGAAGRLDPTAIRVEDLSETHMDPFAKDIRKLLKRKYAVETDKHTGITAVYSIEARRLPVTLQYDDATD
GFLCVCPQDNEFHTCDHRTQIDGSVAFVTSCFGMNAAGVVVRRLASAR

Sequences:

>Translated_288_residues
MNPQPLPAPAPETPPTAPDSLARPFKLSRRFDRTGRLLGDSAMERLANARVVVFGLGGVGSFAAEGLVRSGIGHLTLVDH
DDVCVTNTNRQLHATVKAVGKPKAELMAQRCQEINPAAKVEAVREFYRADVAEQMLQPGQYDFVVDAIDNVKAKLHLLHR
CVTLGVPVVSSMGAAGRLDPTAIRVEDLSETHMDPFAKDIRKLLKRKYAVETDKHTGITAVYSIEARRLPVTLQYDDATD
GFLCVCPQDNEFHTCDHRTQIDGSVAFVTSCFGMNAAGVVVRRLASAR
>Mature_288_residues
MNPQPLPAPAPETPPTAPDSLARPFKLSRRFDRTGRLLGDSAMERLANARVVVFGLGGVGSFAAEGLVRSGIGHLTLVDH
DDVCVTNTNRQLHATVKAVGKPKAELMAQRCQEINPAAKVEAVREFYRADVAEQMLQPGQYDFVVDAIDNVKAKLHLLHR
CVTLGVPVVSSMGAAGRLDPTAIRVEDLSETHMDPFAKDIRKLLKRKYAVETDKHTGITAVYSIEARRLPVTLQYDDATD
GFLCVCPQDNEFHTCDHRTQIDGSVAFVTSCFGMNAAGVVVRRLASAR

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI4885649, Length=145, Percent_Identity=32.4137931034483, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1789177, Length=258, Percent_Identity=39.922480620155, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI87082356, Length=157, Percent_Identity=31.8471337579618, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787048, Length=151, Percent_Identity=35.7615894039735, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17540406, Length=142, Percent_Identity=32.3943661971831, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6322825, Length=190, Percent_Identity=38.4210526315789, Blast_Score=112, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6321790, Length=196, Percent_Identity=30.1020408163265, Blast_Score=105, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6322639, Length=221, Percent_Identity=27.6018099547511, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24582879, Length=142, Percent_Identity=34.5070422535211, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24660640, Length=135, Percent_Identity=31.1111111111111, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 31401; Mature: 31401

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPQPLPAPAPETPPTAPDSLARPFKLSRRFDRTGRLLGDSAMERLANARVVVFGLGGVG
CCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHCCHHHHHHHHCCEEEEEECCCHH
SFAAEGLVRSGIGHLTLVDHDDVCVTNTNRQLHATVKAVGKPKAELMAQRCQEINPAAKV
HHHHHHHHHCCCCCEEEEECCCEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHH
EAVREFYRADVAEQMLQPGQYDFVVDAIDNVKAKLHLLHRCVTLGVPVVSSMGAAGRLDP
HHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCC
TAIRVEDLSETHMDPFAKDIRKLLKRKYAVETDKHTGITAVYSIEARRLPVTLQYDDATD
CEEEEHHCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCEEEEEECCCCC
GFLCVCPQDNEFHTCDHRTQIDGSVAFVTSCFGMNAAGVVVRRLASAR
CEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNPQPLPAPAPETPPTAPDSLARPFKLSRRFDRTGRLLGDSAMERLANARVVVFGLGGVG
CCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHCCHHHHHHHHCCEEEEEECCCHH
SFAAEGLVRSGIGHLTLVDHDDVCVTNTNRQLHATVKAVGKPKAELMAQRCQEINPAAKV
HHHHHHHHHCCCCCEEEEECCCEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHH
EAVREFYRADVAEQMLQPGQYDFVVDAIDNVKAKLHLLHRCVTLGVPVVSSMGAAGRLDP
HHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCC
TAIRVEDLSETHMDPFAKDIRKLLKRKYAVETDKHTGITAVYSIEARRLPVTLQYDDATD
CEEEEHHCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCEEEEEECCCCC
GFLCVCPQDNEFHTCDHRTQIDGSVAFVTSCFGMNAAGVVVRRLASAR
CEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]