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The map label for this gene is yabD [H]

Identifier: 108760274

GI number: 108760274

Start: 2315649

End: 2316446

Strand: Reverse

Name: yabD [H]

Synonym: MXAN_1980

Alternate gene names: 108760274

Gene position: 2316446-2315649 (Counterclockwise)

Preceding gene: 108759170

Following gene: 108762547

Centisome position: 25.34

GC content: 71.43

Gene sequence:

>798_bases
ATGATAGACACCCACTGCCACCTGGATGCGTCCCGCTTCGACGCCGACAGGAATGAAGTCCTCTCGCGCGCCTGGGCCGC
GGGCCTCCACGGCATCGTCATCCCTGGCGTGGGCCCGCATGACTGGGAGCCCTTGCTGGAGATGTCCCGCCAGGATGCCC
GCCTCCAGGTGGGCCTGGGCATCCACCCGCAGCTCCTCCCCGACATGCCCCCGGCAGAGGACGACGCCGTGCTCGAGCAC
CTGGACGCGTTGCTCGCGAAGGGCGGCGCGGCGGCCGTGGGTGAGTGCGGATTGGATGGCCCCAGCCTCCCGGGCGCGCC
GCTGGAACGGCAGGTGATGGTGCTGAAGCGGCACCTCGCGCTGGCGCGCAAGCACGGCCTGCCCGTGCTGATGCACTGCC
ACCGGCTGCACCCAGCCCTCATCGAACTACTGAAGGAGGAGCCCCTCCCCGAGGCCGGCCTGCTCATGCACAGCTACAGC
GGCGGCGTGGAGTTGGCGCGCTTCTATCTCCAGAAGGGCTGCCACTTCTCCTTCGCGGGCCCCGTCACCTGGGCGGAGGC
CCGCAAGCCCCTGGATGCGCTCCGGGCCATCCCCCTGGACCGGCTGATGGCGGAGACGGACGCCCCGGACCAGGCCCCCA
TGCCCCACCGGGGGACGCGCTCCGAGCCGGGCTACCTTCCCCGCATCCTGGAGGGCATGGCCCGCGTCCGGGGGGAGCCC
GTCGAGGAGGTCGCCCGGCAGACGACCGAGAATGCCCGCCGCTTCTTCCGGGAAGCTTTCCCTGCACCTTCGCGGTAG

Upstream 100 bases:

>100_bases
AGGGCGCGTATACCGTCGGCCTTTCCGGGCGCGCGCACCCGGATGCGCAGGAGCACGCAGCGTGTTCCTGAATGAACGGC
CCAAGGGAGCAGCCTGCTCG

Downstream 100 bases:

>100_bases
GCGAGCGGTCGCGTTATAGAGGACCGCCATGAATCCGCAGCCGCTCCCCGCCCCTGCCCCTGAGACTCCGCCCACCGCCC
CGGACTCGCTCGCCCGTCCC

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MIDTHCHLDASRFDADRNEVLSRAWAAGLHGIVIPGVGPHDWEPLLEMSRQDARLQVGLGIHPQLLPDMPPAEDDAVLEH
LDALLAKGGAAAVGECGLDGPSLPGAPLERQVMVLKRHLALARKHGLPVLMHCHRLHPALIELLKEEPLPEAGLLMHSYS
GGVELARFYLQKGCHFSFAGPVTWAEARKPLDALRAIPLDRLMAETDAPDQAPMPHRGTRSEPGYLPRILEGMARVRGEP
VEEVARQTTENARRFFREAFPAPSR

Sequences:

>Translated_265_residues
MIDTHCHLDASRFDADRNEVLSRAWAAGLHGIVIPGVGPHDWEPLLEMSRQDARLQVGLGIHPQLLPDMPPAEDDAVLEH
LDALLAKGGAAAVGECGLDGPSLPGAPLERQVMVLKRHLALARKHGLPVLMHCHRLHPALIELLKEEPLPEAGLLMHSYS
GGVELARFYLQKGCHFSFAGPVTWAEARKPLDALRAIPLDRLMAETDAPDQAPMPHRGTRSEPGYLPRILEGMARVRGEP
VEEVARQTTENARRFFREAFPAPSR
>Mature_265_residues
MIDTHCHLDASRFDADRNEVLSRAWAAGLHGIVIPGVGPHDWEPLLEMSRQDARLQVGLGIHPQLLPDMPPAEDDAVLEH
LDALLAKGGAAAVGECGLDGPSLPGAPLERQVMVLKRHLALARKHGLPVLMHCHRLHPALIELLKEEPLPEAGLLMHSYS
GGVELARFYLQKGCHFSFAGPVTWAEARKPLDALRAIPLDRLMAETDAPDQAPMPHRGTRSEPGYLPRILEGMARVRGEP
VEEVARQTTENARRFFREAFPAPSR

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=265, Percent_Identity=27.1698113207547, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI110349730, Length=266, Percent_Identity=31.5789473684211, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI110349734, Length=266, Percent_Identity=31.5789473684211, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI226061853, Length=272, Percent_Identity=31.25, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI225903439, Length=248, Percent_Identity=27.0161290322581, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI226061614, Length=260, Percent_Identity=29.2307692307692, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI225903424, Length=274, Percent_Identity=26.6423357664234, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI226061595, Length=228, Percent_Identity=29.3859649122807, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI87082439, Length=261, Percent_Identity=32.9501915708812, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787342, Length=259, Percent_Identity=31.6602316602317, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI48994985, Length=270, Percent_Identity=31.1111111111111, Blast_Score=112, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71980746, Length=267, Percent_Identity=25.4681647940075, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17559024, Length=288, Percent_Identity=28.125, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17565396, Length=301, Percent_Identity=26.2458471760797, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17543026, Length=294, Percent_Identity=26.530612244898, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221330018, Length=284, Percent_Identity=26.7605633802817, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24586117, Length=284, Percent_Identity=26.7605633802817, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24648690, Length=285, Percent_Identity=27.0175438596491, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29136; Mature: 29136

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDTHCHLDASRFDADRNEVLSRAWAAGLHGIVIPGVGPHDWEPLLEMSRQDARLQVGLG
CCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHCCCCCEEEECCC
IHPQLLPDMPPAEDDAVLEHLDALLAKGGAAAVGECGLDGPSLPGAPLERQVMVLKRHLA
CCHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
LARKHGLPVLMHCHRLHPALIELLKEEPLPEAGLLMHSYSGGVELARFYLQKGCHFSFAG
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCC
PVTWAEARKPLDALRAIPLDRLMAETDAPDQAPMPHRGTRSEPGYLPRILEGMARVRGEP
CCCHHHHHCHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
VEEVARQTTENARRFFREAFPAPSR
HHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIDTHCHLDASRFDADRNEVLSRAWAAGLHGIVIPGVGPHDWEPLLEMSRQDARLQVGLG
CCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHCCCCCEEEECCC
IHPQLLPDMPPAEDDAVLEHLDALLAKGGAAAVGECGLDGPSLPGAPLERQVMVLKRHLA
CCHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
LARKHGLPVLMHCHRLHPALIELLKEEPLPEAGLLMHSYSGGVELARFYLQKGCHFSFAG
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCC
PVTWAEARKPLDALRAIPLDRLMAETDAPDQAPMPHRGTRSEPGYLPRILEGMARVRGEP
CCCHHHHHCHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
VEEVARQTTENARRFFREAFPAPSR
HHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]