| Definition | Myxococcus xanthus DK 1622 chromosome, complete genome. |
|---|---|
| Accession | NC_008095 |
| Length | 9,139,763 |
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The map label for this gene is mrcA [H]
Identifier: 108762542
GI number: 108762542
Start: 6471724
End: 6474222
Strand: Direct
Name: mrcA [H]
Synonym: MXAN_5181
Alternate gene names: 108762542
Gene position: 6471724-6474222 (Clockwise)
Preceding gene: 108758068
Following gene: 108757380
Centisome position: 70.81
GC content: 69.87
Gene sequence:
>2499_bases GTGTGCCTGGTGCTCGGCGCCATCACCCTGGCGAGCGGCTACGCGTACTACAGCCAGGACCTGCCCTCCGTGGACGCGCT GCGCAACTACCAGCCGCCGCAGGTGACGAAGGTGACGTGCGGTGACGGCACGCTCTGCGCCGAGTTCGCGCACGAGCGGC GCACGTTGATTCGCGTGGAGGACCTGCCGCCCCACGTCCGCAACGCCTTCCTGGCCGCCGAGGACGCGGACTTCTACAAG CACGAGGGCCTGGACTTCTTCGGCATCACCCGCGCGGCCATCAAGAACCTCATCCCCAACAGCCGCAAGTCCGGCGCGTC CACCATCACCCAGCAGGTGGTGAAGAACCTGCTGCTGTCCCCTGAGCGCAGCTTCTCCCGCAAGGCGCGCGAGTGGATTC TCACGCCACGCGTGGAGGAAGCGCTCACCAAGGACCAGATTCTCTCGCTCTACATCAACCAGTCCTACTACGGGCAGCGC CGCTACGGCATGGAGGAGGCGGCGCTCTTCTACTTCGGCAAGCACGCCAAGGACTTGAACGTGGGCGAGGCCGCCGTGCT CGCGGGCACGGTGCAGCTCCCGCACCGCATCAACCCGGTGACGAACATCACGCGGGCGAAGTCGCGTCAGCGCTACGTGC TGGACCAGATGGCGCGCAACGGCTTCGTGTCCGCGGACGTGGCGGAGGCGGAGAAGGAGAAGCCCATCGTCCTGGCTCCC CGGCGGGGCAAGGTGGTGGGGCCGTATTACACGGAGGAGATTCGCCGCACGCTCATCGCGCGCTACGGCGAGCAGGCGGT GATGGAGGGCGGGCTGCGCGTGGACATCGCCATGGTGCCCAAGCTCCAGCTCGCGGCGGAGCAGTCGGTGCGTGACGGCC TGGAGGCGGTGGACCGGCGCCAGGGCTACCGCGGTCCCCGTGGCGCGCTGGAGAAGGGCCAGTGGGAGCGATACCGGGCC CTCATCGCCACGCGCATCGAGGAGGCGGGCCGCCGGCAGAAGGACCAGGGCTACGTCGCGGACCTGTCCTCGCTGGCGAA GGTGGAGAAGGAAGAGCCGAAGACGCCCGAGATCGCGGGTGCGCCCCTGGACCCGCTGGAAGAGGAAGGCACCGAGGAGC AGCGGCCGGACCTGTCGCCCGAAGACGAGGCGCCCCTCTCCGCGGACCAACTCCTGGCGCAGTCCGTGCGCCTCAAGCCC ATGGAGGAAGGCCTGCGCCTCACGGGCTACGTCATGCAGGTGGACGACAAGCGCAACGTGGCCCGCGTGGACCTGGTGGG CCGCACCGCCGAGGTGGCCTTCGCCGCCGCCTCCTGGGCGCGGCAGAAGGGCAAGAGCGCGCCGAAGAAGATTTCCGACG TCTTCACGGAGGGGGAGCTCGTCTTCGTGCGCGTGCTCAAGGCACCGCCCGCGCCAGCCTTCGTGGAAGCGGCGCTGGAC CAGGTTCCCGAGGTGCAGGGCGGGCTGGTGGTCATCCGTCCGGAGAACCGGCACGTGGTGGCGCTGGTGGGCGGCTACGA CGCGGAGCGCTCGTCCTTCAACCGCGCCACGCAGGCGAAGCGGCAGCCTGGCTCGTCCTTCAAGCCATTCCTCTACGCCG CCGCCATGGGCAGTGGCCGCTACACGCCGCTGTCCAAGGTCAATGACGCCCCTGAAGCCGTCCGCGACCCGTACACGGGC AAGACGTGGAAGCCGCAGAACTACGACCGTCGGTTCCACGGGCCGATGACGCTGCGCGAGGCGCTCACCAAGTCGAAGAA CACGGTGTCCGTGCGCCTCATCGAGGCGCTCACCCCGGCCACCACCATCGACGTCGCGCGCCGGGCTGGCATCCACTCCC CGCTGCCGGAGAACCTCACGCTGGCCCTGGGCACCGGTGAAGTCACGATGCTGGAGGCCGCCAACGCCTACGCCACGCTC CAGGCCAATGGCCGCTATGCGGAGCCCTTGCTGCTGCTGCGCGTGCGCGATGCGCGCGGCAAGGTGCTGGAGGAGCATCA GCCGGCCTTCGAGGAGACGCTGCCGCCCGCGGTGGCCTACCTCACCACGTCGCTGATGCGCAGCGTGGTGGAGGACGGCT CGGGCCGGGCCGTGCTCGCGCTGGAGCGCCCCGCCGCTGGCAAGACGGGCACCACGCAGCAGTCCCGCGACACGTGGTTC TCCGGCTACACGGCGGACTGGGTGGCCAGCGCATGGGTGGGCTTCGACAACAACTCGCCGCTGGGCGGCAGTGAGACGGG TGGCCGCGCCGCGCTGCCCATCTGGCTCCAGTTCATGCGCGTGGCCCACGAAGGGCTGCCCACGCGGGAGTTCGAGGTGC CCCCCGGCGTCGTGCAAGTGCGCATCGACCCCATCAGCGGACTGCTGGCGGGCAACTCCGTCCCGGGCCGGCTGGAGCCC TTCCTCGAAGGCACGCAGCCCACCGCGGAGGCACCGCCGCCGGGACAGGTGACCACCGACCAGTTCTTCCTCGACGAAGG CAACAGGCGGGGACTGTGA
Upstream 100 bases:
>100_bases GCCCGATTCCTCCACACCCACTCCCCCCGCGCCGCCTTCGCGACCGGGGTTCGGTGCCCGGCTGTGGCGCTGGACGAAGC GGCTGCTCATCACCGGCCTC
Downstream 100 bases:
>100_bases GCCCTGCCCGAGCCCTGCTGCTCGCCCCTGTGCTGGCCACGCTCGTGGCGCGGGCGGCGCCTGCGGCCGACACCACCGCC GCCATTCCCCGACTCGCCCG
Product: 1A family penicillin-binding protein
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 832; Mature: 832
Protein sequence:
>832_residues MCLVLGAITLASGYAYYSQDLPSVDALRNYQPPQVTKVTCGDGTLCAEFAHERRTLIRVEDLPPHVRNAFLAAEDADFYK HEGLDFFGITRAAIKNLIPNSRKSGASTITQQVVKNLLLSPERSFSRKAREWILTPRVEEALTKDQILSLYINQSYYGQR RYGMEEAALFYFGKHAKDLNVGEAAVLAGTVQLPHRINPVTNITRAKSRQRYVLDQMARNGFVSADVAEAEKEKPIVLAP RRGKVVGPYYTEEIRRTLIARYGEQAVMEGGLRVDIAMVPKLQLAAEQSVRDGLEAVDRRQGYRGPRGALEKGQWERYRA LIATRIEEAGRRQKDQGYVADLSSLAKVEKEEPKTPEIAGAPLDPLEEEGTEEQRPDLSPEDEAPLSADQLLAQSVRLKP MEEGLRLTGYVMQVDDKRNVARVDLVGRTAEVAFAAASWARQKGKSAPKKISDVFTEGELVFVRVLKAPPAPAFVEAALD QVPEVQGGLVVIRPENRHVVALVGGYDAERSSFNRATQAKRQPGSSFKPFLYAAAMGSGRYTPLSKVNDAPEAVRDPYTG KTWKPQNYDRRFHGPMTLREALTKSKNTVSVRLIEALTPATTIDVARRAGIHSPLPENLTLALGTGEVTMLEAANAYATL QANGRYAEPLLLLRVRDARGKVLEEHQPAFEETLPPAVAYLTTSLMRSVVEDGSGRAVLALERPAAGKTGTTQQSRDTWF SGYTADWVASAWVGFDNNSPLGGSETGGRAALPIWLQFMRVAHEGLPTREFEVPPGVVQVRIDPISGLLAGNSVPGRLEP FLEGTQPTAEAPPPGQVTTDQFFLDEGNRRGL
Sequences:
>Translated_832_residues MCLVLGAITLASGYAYYSQDLPSVDALRNYQPPQVTKVTCGDGTLCAEFAHERRTLIRVEDLPPHVRNAFLAAEDADFYK HEGLDFFGITRAAIKNLIPNSRKSGASTITQQVVKNLLLSPERSFSRKAREWILTPRVEEALTKDQILSLYINQSYYGQR RYGMEEAALFYFGKHAKDLNVGEAAVLAGTVQLPHRINPVTNITRAKSRQRYVLDQMARNGFVSADVAEAEKEKPIVLAP RRGKVVGPYYTEEIRRTLIARYGEQAVMEGGLRVDIAMVPKLQLAAEQSVRDGLEAVDRRQGYRGPRGALEKGQWERYRA LIATRIEEAGRRQKDQGYVADLSSLAKVEKEEPKTPEIAGAPLDPLEEEGTEEQRPDLSPEDEAPLSADQLLAQSVRLKP MEEGLRLTGYVMQVDDKRNVARVDLVGRTAEVAFAAASWARQKGKSAPKKISDVFTEGELVFVRVLKAPPAPAFVEAALD QVPEVQGGLVVIRPENRHVVALVGGYDAERSSFNRATQAKRQPGSSFKPFLYAAAMGSGRYTPLSKVNDAPEAVRDPYTG KTWKPQNYDRRFHGPMTLREALTKSKNTVSVRLIEALTPATTIDVARRAGIHSPLPENLTLALGTGEVTMLEAANAYATL QANGRYAEPLLLLRVRDARGKVLEEHQPAFEETLPPAVAYLTTSLMRSVVEDGSGRAVLALERPAAGKTGTTQQSRDTWF SGYTADWVASAWVGFDNNSPLGGSETGGRAALPIWLQFMRVAHEGLPTREFEVPPGVVQVRIDPISGLLAGNSVPGRLEP FLEGTQPTAEAPPPGQVTTDQFFLDEGNRRGL >Mature_832_residues MCLVLGAITLASGYAYYSQDLPSVDALRNYQPPQVTKVTCGDGTLCAEFAHERRTLIRVEDLPPHVRNAFLAAEDADFYK HEGLDFFGITRAAIKNLIPNSRKSGASTITQQVVKNLLLSPERSFSRKAREWILTPRVEEALTKDQILSLYINQSYYGQR RYGMEEAALFYFGKHAKDLNVGEAAVLAGTVQLPHRINPVTNITRAKSRQRYVLDQMARNGFVSADVAEAEKEKPIVLAP RRGKVVGPYYTEEIRRTLIARYGEQAVMEGGLRVDIAMVPKLQLAAEQSVRDGLEAVDRRQGYRGPRGALEKGQWERYRA LIATRIEEAGRRQKDQGYVADLSSLAKVEKEEPKTPEIAGAPLDPLEEEGTEEQRPDLSPEDEAPLSADQLLAQSVRLKP MEEGLRLTGYVMQVDDKRNVARVDLVGRTAEVAFAAASWARQKGKSAPKKISDVFTEGELVFVRVLKAPPAPAFVEAALD QVPEVQGGLVVIRPENRHVVALVGGYDAERSSFNRATQAKRQPGSSFKPFLYAAAMGSGRYTPLSKVNDAPEAVRDPYTG KTWKPQNYDRRFHGPMTLREALTKSKNTVSVRLIEALTPATTIDVARRAGIHSPLPENLTLALGTGEVTMLEAANAYATL QANGRYAEPLLLLRVRDARGKVLEEHQPAFEETLPPAVAYLTTSLMRSVVEDGSGRAVLALERPAAGKTGTTQQSRDTWF SGYTADWVASAWVGFDNNSPLGGSETGGRAALPIWLQFMRVAHEGLPTREFEVPPGVVQVRIDPISGLLAGNSVPGRLEP FLEGTQPTAEAPPPGQVTTDQFFLDEGNRRGL
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=313, Percent_Identity=38.0191693290735, Blast_Score=219, Evalue=6e-58, Organism=Escherichia coli, GI1786343, Length=306, Percent_Identity=36.2745098039216, Blast_Score=139, Evalue=1e-33, Organism=Escherichia coli, GI1788867, Length=221, Percent_Identity=33.9366515837104, Blast_Score=116, Evalue=5e-27, Organism=Escherichia coli, GI1789601, Length=165, Percent_Identity=37.5757575757576, Blast_Score=99, Evalue=1e-21,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 91490; Mature: 91490
Theoretical pI: Translated: 8.04; Mature: 8.04
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 1.8 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 1.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MCLVLGAITLASGYAYYSQDLPSVDALRNYQPPQVTKVTCGDGTLCAEFAHERRTLIRVE CEEEEEEHHHHCCCHHHHCCCCCHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCEEEEEC DLPPHVRNAFLAAEDADFYKHEGLDFFGITRAAIKNLIPNSRKSGASTITQQVVKNLLLS CCCHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC PERSFSRKAREWILTPRVEEALTKDQILSLYINQSYYGQRRYGMEEAALFYFGKHAKDLN CCHHHHHHHHHHCCCCCHHHHHHHHHHEEEEECCCCCCHHHCCHHHHHHHHHCCCCCCCC VGEAAVLAGTVQLPHRINPVTNITRAKSRQRYVLDQMARNGFVSADVAEAEKEKPIVLAP CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEC RRGKVVGPYYTEEIRRTLIARYGEQAVMEGGLRVDIAMVPKLQLAAEQSVRDGLEAVDRR CCCCEECCHHHHHHHHHHHHHHCCHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH QGYRGPRGALEKGQWERYRALIATRIEEAGRRQKDQGYVADLSSLAKVEKEEPKTPEIAG CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC APLDPLEEEGTEEQRPDLSPEDEAPLSADQLLAQSVRLKPMEEGLRLTGYVMQVDDKRNV CCCCCHHHCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHCCCEEEEEEEEECCCCCE ARVDLVGRTAEVAFAAASWARQKGKSAPKKISDVFTEGELVFVRVLKAPPAPAFVEAALD EEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHH QVPEVQGGLVVIRPENRHVVALVGGYDAERSSFNRATQAKRQPGSSFKPFLYAAAMGSGR HCCCCCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCC YTPLSKVNDAPEAVRDPYTGKTWKPQNYDRRFHGPMTLREALTKSKNTVSVRLIEALTPA CCCHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEHHHCCH TTIDVARRAGIHSPLPENLTLALGTGEVTMLEAANAYATLQANGRYAEPLLLLRVRDARG HHHHHHHHCCCCCCCCCCEEEEECCCCEEEEECCCCEEEEECCCCCCCCEEEEEEECCCC KVLEEHQPAFEETLPPAVAYLTTSLMRSVVEDGSGRAVLALERPAAGKTGTTQQSRDTWF CHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCC SGYTADWVASAWVGFDNNSPLGGSETGGRAALPIWLQFMRVAHEGLPTREFEVPPGVVQV CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE RIDPISGLLAGNSVPGRLEPFLEGTQPTAEAPPPGQVTTDQFFLDEGNRRGL EECCCCCEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCC >Mature Secondary Structure MCLVLGAITLASGYAYYSQDLPSVDALRNYQPPQVTKVTCGDGTLCAEFAHERRTLIRVE CEEEEEEHHHHCCCHHHHCCCCCHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCEEEEEC DLPPHVRNAFLAAEDADFYKHEGLDFFGITRAAIKNLIPNSRKSGASTITQQVVKNLLLS CCCHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC PERSFSRKAREWILTPRVEEALTKDQILSLYINQSYYGQRRYGMEEAALFYFGKHAKDLN CCHHHHHHHHHHCCCCCHHHHHHHHHHEEEEECCCCCCHHHCCHHHHHHHHHCCCCCCCC VGEAAVLAGTVQLPHRINPVTNITRAKSRQRYVLDQMARNGFVSADVAEAEKEKPIVLAP CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEC RRGKVVGPYYTEEIRRTLIARYGEQAVMEGGLRVDIAMVPKLQLAAEQSVRDGLEAVDRR CCCCEECCHHHHHHHHHHHHHHCCHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH QGYRGPRGALEKGQWERYRALIATRIEEAGRRQKDQGYVADLSSLAKVEKEEPKTPEIAG CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC APLDPLEEEGTEEQRPDLSPEDEAPLSADQLLAQSVRLKPMEEGLRLTGYVMQVDDKRNV CCCCCHHHCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHCCCEEEEEEEEECCCCCE ARVDLVGRTAEVAFAAASWARQKGKSAPKKISDVFTEGELVFVRVLKAPPAPAFVEAALD EEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHH QVPEVQGGLVVIRPENRHVVALVGGYDAERSSFNRATQAKRQPGSSFKPFLYAAAMGSGR HCCCCCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCC YTPLSKVNDAPEAVRDPYTGKTWKPQNYDRRFHGPMTLREALTKSKNTVSVRLIEALTPA CCCHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEHHHCCH TTIDVARRAGIHSPLPENLTLALGTGEVTMLEAANAYATLQANGRYAEPLLLLRVRDARG HHHHHHHHCCCCCCCCCCEEEEECCCCEEEEECCCCEEEEECCCCCCCCEEEEEEECCCC KVLEEHQPAFEETLPPAVAYLTTSLMRSVVEDGSGRAVLALERPAAGKTGTTQQSRDTWF CHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCC SGYTADWVASAWVGFDNNSPLGGSETGGRAALPIWLQFMRVAHEGLPTREFEVPPGVVQV CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE RIDPISGLLAGNSVPGRLEPFLEGTQPTAEAPPPGQVTTDQFFLDEGNRRGL EECCCCCEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9823893 [H]