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The map label for this gene is fabD [H]

Identifier: 108762541

GI number: 108762541

Start: 4800583

End: 4802556

Strand: Reverse

Name: fabD [H]

Synonym: MXAN_3942

Alternate gene names: 108762541

Gene position: 4802556-4800583 (Counterclockwise)

Preceding gene: 108757259

Following gene: 108763709

Centisome position: 52.55

GC content: 67.93

Gene sequence:

>1974_bases
GTGAACATCATGGTCGATTCAGTGTCGAAACAGGCACGGCGGAAGGTGTTTCTTTTTTCCGGCCAGGGCACCCAGTCGTA
CTTCATGGCCAAGGAGCTGTTTGACACCCAGACGGGGTTCAAGCGGCAGCTGCTGGAGCTGGACGAGCAATTCAAGCAGC
GGCTGGGGCACTCGATTCTCGAGCGAATCTATGACGCGCGCGCCGCGCGGTTGGATCCGCTCGACGATGTCCTGGTGTCC
TTTCCCGCCATCTTCATGATTGAGCATGCGCTGGCGCGGCTGCTCATCGACCGGGGTATCCAGCCGGACGCTGTCGTGGG
CGCCAGCATGGGCGAGGTGGCGGCGGCGGCGATTGCGGGCGCAATCTCAGTGGACGCGGCCGTGGCCCTGGTGGCGGCGC
AGGCCCAGCTCTTTGCCCGTACGGCGCCGCGGGGCGGCATGCTCGCGGTGCTTCACGAACTGGAAGCCTGCCGGGGCTTC
ACGTCCGTCGCGCGGGATGGCGAGGTTGCAGCCATCAACTACCCGTCGAACTTCGTCCTTGCGGCGGATGAGGCGGGCCT
GGGACGGATTCAGCAGGAACTCTCCCAACGCTCGGTGGCGTTCCACCGGTTGCCGGTGCGCTACCCCTTTCATTCCTCGC
ACCTGGACCCGCTGAGGGAGGAGTACCGAAGCCGCGTCCGCGCGGATTCGCTGACGTGGCCGCGAATCCCCATGTACTCG
TGCACCACCGCGAACCGGGTGCACGACCTGCGCAGCGACCACTTCTGGAACGTGGTCCGCGCGCCCATCCAGCTGTACGA
CACCGTCCTGCAACTGGAGGGGCAGGGCGGCTGCGACTTCATCGACGTCGGCCCCGCCGCGTCCTTCGCGACCATCATCA
AGCGCATCCTCGCGCGGGACTCCACGTCACGGCTCTTCCCGTTGCTCAGCCCCTTCTCCCGCATCGACCGGGAGCTCGAT
GGGGTGACGCGGAGCTGCGCGATGACGGAGGCGCCCGCACCCAGGGCGCCTGCGCAGGTGCCGCCGCCGCCGAGCTCGCC
CTGGGCGCTGCACACCCGAGGAGCGGCGAGCGCGCCGGTGAATGCCCGCAAGGCCGCGCTCTTCCCGGGGCAGGGCTCGC
AGGAGCGCGGCATGGGGGCCGCGCTCTTCGACGAGTTCCCGGACCTGACGGACATCGCCGACGCCATCCTGGGGTATTCC
ATCAAGCGTCTCTGTTTGGAGGACCCAGGCAAGGAGCTGGCGCAGACGCAGTTCACCCAGCCGGCGTTGTACGTGGTGAA
CGCGCTCAGCTACCTGAAGCGGCTGCGTGAAGGAGCGGAGCAGCCGGCCTTCGTCGCGGGCCACAGCCTGGGCGAGTACA
ACGCGCTGCTGGTCGCGGGGGCCTTCGACTTCGAGACGGGACTGCGGCTGGTGAAGCGGCGGGGCGAACTCATGAGCGGC
GCGTCCGGAGGGACCATGGCCGCGGTGGTGGGCTGTGATGCCGTGGCCGTGGAACAGGTCCTTCGAGACCGTCAGCTGAC
CAGTCTGGATATCGCCAACATCAACTCGCCCGACCAGATTGTGGTCTCCGGACCGGCGCAGGACATCGAGCGGGCACGGC
AGTGTTTCGTGGACCGTGGCGCGCGGTACGTTCCGCTCAACGTGCGAGCGCCGTTTCACTCGCGCTACATGCAGCCGGCC
GCCAGCGAGTTCGAGCGCTTCCTGTCTCAGTTCCAGTACGCGCCGCTCCGGTGCGTGGTCATCTCCAACGTCACGGGCCG
ACCTTACGCTCATGACAACGTGGTGCAGGGGCTGGCTCTGCAACTGCGCAGCCCGGTGCAGTGGACGGCCACCGTCCGCT
ACCTCCTGGAACAGGGCGTGGAGGACTTCGAGGAGCTGGGCCCCGGCCGCGTGCTGACCCGCCTCATCACCGCGAACAAG
CGGGGCGCCCCCGCACCGGCCACCGCCGCGCCCGCGAAGTGGGCGAATGCCTGA

Upstream 100 bases:

>100_bases
GTGCGCCGGAGCAACACGCTGGCGCCGTCTCAGGGCGTGCCCATCATCGTCGAGTCGCGGCTGCCGAGCTGAACCGCTTG
GCCCCACCATCTCCAGCGCG

Downstream 100 bases:

>100_bases
GCCCTCCGGAGCGTCGTTGAAATCCTCGGCCGGTGGGCCGTCCGGCTGCTGAGACCACTGAATGTCCACCTCACCTGTGC
AGGAGCTGGTTGTCTCGGGG

Product: acyltranferase/malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: AT [H]

Number of amino acids: Translated: 657; Mature: 657

Protein sequence:

>657_residues
MNIMVDSVSKQARRKVFLFSGQGTQSYFMAKELFDTQTGFKRQLLELDEQFKQRLGHSILERIYDARAARLDPLDDVLVS
FPAIFMIEHALARLLIDRGIQPDAVVGASMGEVAAAAIAGAISVDAAVALVAAQAQLFARTAPRGGMLAVLHELEACRGF
TSVARDGEVAAINYPSNFVLAADEAGLGRIQQELSQRSVAFHRLPVRYPFHSSHLDPLREEYRSRVRADSLTWPRIPMYS
CTTANRVHDLRSDHFWNVVRAPIQLYDTVLQLEGQGGCDFIDVGPAASFATIIKRILARDSTSRLFPLLSPFSRIDRELD
GVTRSCAMTEAPAPRAPAQVPPPPSSPWALHTRGAASAPVNARKAALFPGQGSQERGMGAALFDEFPDLTDIADAILGYS
IKRLCLEDPGKELAQTQFTQPALYVVNALSYLKRLREGAEQPAFVAGHSLGEYNALLVAGAFDFETGLRLVKRRGELMSG
ASGGTMAAVVGCDAVAVEQVLRDRQLTSLDIANINSPDQIVVSGPAQDIERARQCFVDRGARYVPLNVRAPFHSRYMQPA
ASEFERFLSQFQYAPLRCVVISNVTGRPYAHDNVVQGLALQLRSPVQWTATVRYLLEQGVEDFEELGPGRVLTRLITANK
RGAPAPATAAPAKWANA

Sequences:

>Translated_657_residues
MNIMVDSVSKQARRKVFLFSGQGTQSYFMAKELFDTQTGFKRQLLELDEQFKQRLGHSILERIYDARAARLDPLDDVLVS
FPAIFMIEHALARLLIDRGIQPDAVVGASMGEVAAAAIAGAISVDAAVALVAAQAQLFARTAPRGGMLAVLHELEACRGF
TSVARDGEVAAINYPSNFVLAADEAGLGRIQQELSQRSVAFHRLPVRYPFHSSHLDPLREEYRSRVRADSLTWPRIPMYS
CTTANRVHDLRSDHFWNVVRAPIQLYDTVLQLEGQGGCDFIDVGPAASFATIIKRILARDSTSRLFPLLSPFSRIDRELD
GVTRSCAMTEAPAPRAPAQVPPPPSSPWALHTRGAASAPVNARKAALFPGQGSQERGMGAALFDEFPDLTDIADAILGYS
IKRLCLEDPGKELAQTQFTQPALYVVNALSYLKRLREGAEQPAFVAGHSLGEYNALLVAGAFDFETGLRLVKRRGELMSG
ASGGTMAAVVGCDAVAVEQVLRDRQLTSLDIANINSPDQIVVSGPAQDIERARQCFVDRGARYVPLNVRAPFHSRYMQPA
ASEFERFLSQFQYAPLRCVVISNVTGRPYAHDNVVQGLALQLRSPVQWTATVRYLLEQGVEDFEELGPGRVLTRLITANK
RGAPAPATAAPAKWANA
>Mature_657_residues
MNIMVDSVSKQARRKVFLFSGQGTQSYFMAKELFDTQTGFKRQLLELDEQFKQRLGHSILERIYDARAARLDPLDDVLVS
FPAIFMIEHALARLLIDRGIQPDAVVGASMGEVAAAAIAGAISVDAAVALVAAQAQLFARTAPRGGMLAVLHELEACRGF
TSVARDGEVAAINYPSNFVLAADEAGLGRIQQELSQRSVAFHRLPVRYPFHSSHLDPLREEYRSRVRADSLTWPRIPMYS
CTTANRVHDLRSDHFWNVVRAPIQLYDTVLQLEGQGGCDFIDVGPAASFATIIKRILARDSTSRLFPLLSPFSRIDRELD
GVTRSCAMTEAPAPRAPAQVPPPPSSPWALHTRGAASAPVNARKAALFPGQGSQERGMGAALFDEFPDLTDIADAILGYS
IKRLCLEDPGKELAQTQFTQPALYVVNALSYLKRLREGAEQPAFVAGHSLGEYNALLVAGAFDFETGLRLVKRRGELMSG
ASGGTMAAVVGCDAVAVEQVLRDRQLTSLDIANINSPDQIVVSGPAQDIERARQCFVDRGARYVPLNVRAPFHSRYMQPA
ASEFERFLSQFQYAPLRCVVISNVTGRPYAHDNVVQGLALQLRSPVQWTATVRYLLEQGVEDFEELGPGRVLTRLITANK
RGAPAPATAAPAKWANA

Specific function: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. It catalyzes the transfer of the malonyl-CoA group to the acyl-carrier-protein AcpK (Mal-AcpK) [H]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=344, Percent_Identity=31.1046511627907, Blast_Score=111, Evalue=3e-24,
Organism=Escherichia coli, GI1787334, Length=280, Percent_Identity=37.1428571428571, Blast_Score=165, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71984332, Length=302, Percent_Identity=26.158940397351, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17550940, Length=337, Percent_Identity=25.2225519287834, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24665753, Length=304, Percent_Identity=34.2105263157895, Blast_Score=115, Evalue=8e-26,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 71809; Mature: 71809

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIMVDSVSKQARRKVFLFSGQGTQSYFMAKELFDTQTGFKRQLLELDEQFKQRLGHSIL
CCCCHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERIYDARAARLDPLDDVLVSFPAIFMIEHALARLLIDRGIQPDAVVGASMGEVAAAAIAG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHH
AISVDAAVALVAAQAQLFARTAPRGGMLAVLHELEACRGFTSVARDGEVAAINYPSNFVL
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEE
AADEAGLGRIQQELSQRSVAFHRLPVRYPFHSSHLDPLREEYRSRVRADSLTWPRIPMYS
EECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEE
CTTANRVHDLRSDHFWNVVRAPIQLYDTVLQLEGQGGCDFIDVGPAASFATIIKRILARD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHCC
STSRLFPLLSPFSRIDRELDGVTRSCAMTEAPAPRAPAQVPPPPSSPWALHTRGAASAPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCC
NARKAALFPGQGSQERGMGAALFDEFPDLTDIADAILGYSIKRLCLEDPGKELAQTQFTQ
CCCCEEECCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
PALYVVNALSYLKRLREGAEQPAFVAGHSLGEYNALLVAGAFDFETGLRLVKRRGELMSG
HHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCC
ASGGTMAAVVGCDAVAVEQVLRDRQLTSLDIANINSPDQIVVSGPAQDIERARQCFVDRG
CCCCCEEEECCCHHHHHHHHHHCCCCCEEEECCCCCCCEEEEECCHHHHHHHHHHHHHCC
ARYVPLNVRAPFHSRYMQPAASEFERFLSQFQYAPLRCVVISNVTGRPYAHDNVVQGLAL
CEEEEEECCCCHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHH
QLRSPVQWTATVRYLLEQGVEDFEELGPGRVLTRLITANKRGAPAPATAAPAKWANA
HHCCCCHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNIMVDSVSKQARRKVFLFSGQGTQSYFMAKELFDTQTGFKRQLLELDEQFKQRLGHSIL
CCCCHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERIYDARAARLDPLDDVLVSFPAIFMIEHALARLLIDRGIQPDAVVGASMGEVAAAAIAG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHH
AISVDAAVALVAAQAQLFARTAPRGGMLAVLHELEACRGFTSVARDGEVAAINYPSNFVL
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEE
AADEAGLGRIQQELSQRSVAFHRLPVRYPFHSSHLDPLREEYRSRVRADSLTWPRIPMYS
EECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEE
CTTANRVHDLRSDHFWNVVRAPIQLYDTVLQLEGQGGCDFIDVGPAASFATIIKRILARD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHCC
STSRLFPLLSPFSRIDRELDGVTRSCAMTEAPAPRAPAQVPPPPSSPWALHTRGAASAPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCC
NARKAALFPGQGSQERGMGAALFDEFPDLTDIADAILGYSIKRLCLEDPGKELAQTQFTQ
CCCCEEECCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
PALYVVNALSYLKRLREGAEQPAFVAGHSLGEYNALLVAGAFDFETGLRLVKRRGELMSG
HHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCC
ASGGTMAAVVGCDAVAVEQVLRDRQLTSLDIANINSPDQIVVSGPAQDIERARQCFVDRG
CCCCCEEEECCCHHHHHHHHHHCCCCCEEEECCCCCCCEEEEECCHHHHHHHHHHHHHCC
ARYVPLNVRAPFHSRYMQPAASEFERFLSQFQYAPLRCVVISNVTGRPYAHDNVVQGLAL
CEEEEEECCCCHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHH
QLRSPVQWTATVRYLLEQGVEDFEELGPGRVLTRLITANKRGAPAPATAAPAKWANA
HHCCCCHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA