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The map label for this gene is cysD

Identifier: 108762479

GI number: 108762479

Start: 2717663

End: 2718580

Strand: Reverse

Name: cysD

Synonym: MXAN_2337

Alternate gene names: 108762479

Gene position: 2718580-2717663 (Counterclockwise)

Preceding gene: 108761459

Following gene: 108760381

Centisome position: 29.74

GC content: 68.3

Gene sequence:

>918_bases
ATGAGTGAGCACACGTTCGCGCGGGCGTCCCACCTGTCGGAGCTGGAAGCGGAGAGCATCCACATCCTCCGGGAGACGGT
GGCCGAGTTCGCCAACCCGGTGATGCTCTACAGCATCGGCAAGGACTCCCAGGTCCTGCTGCACCTGGCGCGCAAGGCCT
TCCACCCCGCGCCCCTGCCCTTCCCGCTGCTCCACGTGGACACCACCTGGAAGTTCCGGGACATGTATGCGTTCCGGGAC
GCCTTCGTGGCGCGCCACGGACTGCGCCTCATCATCCACCGGAACCAGCGCGCGCTGGCCGAGGGCATCAACCCCTTCGA
CCACGGCAGCCAGAAGTACACCCATGCGATGAAGACGCAGGCGCTGCTGGAGGCGCTGGCGGCGCATGGCTTCGACGCGG
CCTTCGGTGGCGCGCGGCGCGACGAGGAGAAGTCCCGCGCCAAGGAGCGGGTGTTCTCCTTCCGGGACCGGCACGGACAG
TGGGACCCGCGCCGCCAGCGGCCGGAGCTGTGGAACCTCTTCAACGGCCGCGTCGACGCGGGCGAGAGCATGCGCGTCTT
CCCGCTGTCCAACTGGACGGAGCTGGACGTGTGGCACTACGTGCTGCGCGAGCGCATCCCCGTGGTGCCGCTCTACTTCG
CCGCGGAGCGTCCTGTCATTGACCGGGGCGGCACGCTGCTCATGGTGGATGACGAGCGCATGCGGCTTCGGCCCGGGGAG
AAGCCCGAAATCCGGCGCGTGCGCTTCCGGACCCTGGGCTGCTACCCGCTCAGCGGCGCCATCGAATCCTCCGCCACCAC
GGTGGAGACCGTCATCCACGAGATGGTGAACGCCCGCCAGTCCGAGCGGCAGGGCCGACTCATCGACCACGACGAAGAGG
GCTCCATGGAGCTCAAGAAGCGCGAGGGCTACTTCTAA

Upstream 100 bases:

>100_bases
GTGGGCGAGGTCGTCTCGCTGCGCGGGCGCCTGCCTTCGCTGGTAGCGCAAGGAACCTCGGAGCATGGACACGCGCCAGC
GCGCGTGGCGGAGGGCGGTC

Downstream 100 bases:

>100_bases
TGGACACCGGCTTGCAGCAACTGCTCGACCAGCATGCCTCCCGGGAGCTGCTCCGGCTCGTCGTGGTCGGCTCCGTGGAT
GACGGGAAGTCCACCCTCAT

Product: sulfate adenylyltransferase subunit 2

Products: NA

Alternate protein names: ATP-sulfurylase small subunit; Sulfate adenylate transferase; SAT

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSEHTFARASHLSELEAESIHILRETVAEFANPVMLYSIGKDSQVLLHLARKAFHPAPLPFPLLHVDTTWKFRDMYAFRD
AFVARHGLRLIIHRNQRALAEGINPFDHGSQKYTHAMKTQALLEALAAHGFDAAFGGARRDEEKSRAKERVFSFRDRHGQ
WDPRRQRPELWNLFNGRVDAGESMRVFPLSNWTELDVWHYVLRERIPVVPLYFAAERPVIDRGGTLLMVDDERMRLRPGE
KPEIRRVRFRTLGCYPLSGAIESSATTVETVIHEMVNARQSERQGRLIDHDEEGSMELKKREGYF

Sequences:

>Translated_305_residues
MSEHTFARASHLSELEAESIHILRETVAEFANPVMLYSIGKDSQVLLHLARKAFHPAPLPFPLLHVDTTWKFRDMYAFRD
AFVARHGLRLIIHRNQRALAEGINPFDHGSQKYTHAMKTQALLEALAAHGFDAAFGGARRDEEKSRAKERVFSFRDRHGQ
WDPRRQRPELWNLFNGRVDAGESMRVFPLSNWTELDVWHYVLRERIPVVPLYFAAERPVIDRGGTLLMVDDERMRLRPGE
KPEIRRVRFRTLGCYPLSGAIESSATTVETVIHEMVNARQSERQGRLIDHDEEGSMELKKREGYF
>Mature_304_residues
SEHTFARASHLSELEAESIHILRETVAEFANPVMLYSIGKDSQVLLHLARKAFHPAPLPFPLLHVDTTWKFRDMYAFRDA
FVARHGLRLIIHRNQRALAEGINPFDHGSQKYTHAMKTQALLEALAAHGFDAAFGGARRDEEKSRAKERVFSFRDRHGQW
DPRRQRPELWNLFNGRVDAGESMRVFPLSNWTELDVWHYVLRERIPVVPLYFAAERPVIDRGGTLLMVDDERMRLRPGEK
PEIRRVRFRTLGCYPLSGAIESSATTVETVIHEMVNARQSERQGRLIDHDEEGSMELKKREGYF

Specific function: First step in the sulfate activation pathway. This reaction occurs early in the reductive branch of the cysteine biosynthetic pathway. [C]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysD subfamily

Homologues:

Organism=Escherichia coli, GI1789109, Length=298, Percent_Identity=65.1006711409396, Blast_Score=422, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYSD_MYXXD (Q1D9W6)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_630557.1
- ProteinModelPortal:   Q1D9W6
- SMR:   Q1D9W6
- STRING:   Q1D9W6
- GeneID:   4106229
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_2337
- TIGR:   MXAN_2337
- eggNOG:   COG0175
- HOGENOM:   HBG758022
- OMA:   HYGFDAA
- PhylomeDB:   Q1D9W6
- ProtClustDB:   PRK05253
- BioCyc:   MXAN246197:MXAN_2337-MONOMER
- HAMAP:   MF_00064
- InterPro:   IPR002500
- InterPro:   IPR014729
- InterPro:   IPR011784
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF002936
- TIGRFAMs:   TIGR02039

Pfam domain/function: PF01507 PAPS_reduct

EC number: =2.7.7.4

Molecular weight: Translated: 35339; Mature: 35208

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHTFARASHLSELEAESIHILRETVAEFANPVMLYSIGKDSQVLLHLARKAFHPAPLP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCCC
FPLLHVDTTWKFRDMYAFRDAFVARHGLRLIIHRNQRALAEGINPFDHGSQKYTHAMKTQ
CEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHCCCCCCCCCHHHHHHHHHH
ALLEALAAHGFDAAFGGARRDEEKSRAKERVFSFRDRHGQWDPRRQRPELWNLFNGRVDA
HHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCC
GESMRVFPLSNWTELDVWHYVLRERIPVVPLYFAAERPVIDRGGTLLMVDDERMRLRPGE
CCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCEECCCCEEEEECCCHHHCCCCC
KPEIRRVRFRTLGCYPLSGAIESSATTVETVIHEMVNARQSERQGRLIDHDEEGSMELKK
CCHHHHHHHHEECCEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
REGYF
CCCCC
>Mature Secondary Structure 
SEHTFARASHLSELEAESIHILRETVAEFANPVMLYSIGKDSQVLLHLARKAFHPAPLP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCCC
FPLLHVDTTWKFRDMYAFRDAFVARHGLRLIIHRNQRALAEGINPFDHGSQKYTHAMKTQ
CEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHCCCCCCCCCHHHHHHHHHH
ALLEALAAHGFDAAFGGARRDEEKSRAKERVFSFRDRHGQWDPRRQRPELWNLFNGRVDA
HHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCC
GESMRVFPLSNWTELDVWHYVLRERIPVVPLYFAAERPVIDRGGTLLMVDDERMRLRPGE
CCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCEECCCCEEEEECCCHHHCCCCC
KPEIRRVRFRTLGCYPLSGAIESSATTVETVIHEMVNARQSERQGRLIDHDEEGSMELKK
CCHHHHHHHHEECCEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
REGYF
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA