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The map label for this gene is cysN [H]

Identifier: 108760381

GI number: 108760381

Start: 2715951

End: 2717663

Strand: Reverse

Name: cysN [H]

Synonym: MXAN_2336

Alternate gene names: 108760381

Gene position: 2717663-2715951 (Counterclockwise)

Preceding gene: 108762479

Following gene: 108761948

Centisome position: 29.73

GC content: 71.1

Gene sequence:

>1713_bases
ATGGACACCGGCTTGCAGCAACTGCTCGACCAGCATGCCTCCCGGGAGCTGCTCCGGCTCGTCGTGGTCGGCTCCGTGGA
TGACGGGAAGTCCACCCTCATCGGCAGGCTCCTCTACGAGTGCGACGGGCTCTTCGAGGACCAGATTTCCGCCGTGCGGA
AGGCCAGCGCGAAGCGGACCGCCGCCGCCGTGTCCGTGCCCTCCGAGGTGCTGGTCCAAGGCCTGAAGGCCGCGGCCGGC
GCGGACGGGGAGGAACTGGACTTCTCCCTCTTCACCGACGGCCTGCGCGCCGAGCGTGAGCAGGGCATCACCATCGACGT
TGCCTACCGCTACCTCAGCACCGCGCGGCGCAAGGTCATCGTCGCGGACACGCCGGGCCACATCCAGTACACGCGCAACA
TGGCCACCGGCGCCTCCACGGCGGACGCGGCGGTCATCCTGGTGGACGCGCGACTGGGCGTGCTGCCGCAGACGCGCCGC
CACGCGTACATCGCCTCGCTGCTGGGCATCCCCTACCTGGCCGTGGCGGTGAACAAGATGGACCTCACGGGCTTCGACCG
CGGCGCCTTCGAGCGCATCGGCGCCGAGCTGGTGGACTTCGCCCACGCGCTCGGCTTCGAGGGCGTGCGGCTCTTCCCCA
TCAGCGCCAGTCGCGGGGACAACATCACCCGGCCCAGCGCCCGCACGCCCTGGCATGAAGGCGGCAGCCTGCTCGCATGG
CTGGAGTCCCTGCCCCACCAGCGCCGGCAGGACGACGCGCCCTTCCGCTTCCCCGTTCAGTACGTGCTCCGACCCCACCA
GGACTACCGAGGGCTGGCGGGACAGATTGCCTCCGGCACCGTCCGCGTCGGGGATGAAATCCAGGTCCATCCCTCCGGGC
GGCGCACGCGCGTGGCGGGCATCGACACCTTCGACGGACCGCTGGAGGAGGCCGCGTCCCCCGCGTCCGTCACGCTGCGA
CTCGCGGACGAAGTGGACGCCAGCCGAGGCGACGTGCTGGCCCATGTGGACCAGCCGCCGCTGTCTCTCCACCAGCTCGA
CGCGATGCTCGTGTGGTTTGGAGAACAACCGCTGGACTGCTCGCGCCGCTACCTGGTGAAGCAGGCCTCGCGGACCGCGC
CCGCGCACATCGAGCGGGTGCTGTGGCGCAAGGAACTGGCGGACCTGTCCGAGCAACCCGCCGAGTCCCTGTCGCTCAAC
GACATCGGCCGGGTGCGGGTGGTGTGCCGTCGGCCGCTGCTGACCGACCCGTACCGCGACAACCGCCGCACGGGCGCCTT
CATCGTCATCGACGCGCTCACGCACGACACGGTGGCCGCGGGCATGGTCCTGGGTCCCGCGGAGGAGTCGACGAAGAGCG
ACGTGGCCTCCTCGCTCGTCACGCAGCCCGAGCGGCGGGGACGGCTGGGGCAGCCCGGTGCCATTGTCCTGCTACCCGCC
ACGCCGGACGCGGGCTCACGCGCATTCCAGTTGGAGCGCCGGCTGTTCGACCTGGGCTGGCACGTCACCACCACCCCCGG
TGATGTGGAGGTCGCGCTGGCGCTCGCGGCGGCGGGATTGGTGGCCCTGGTCCACACCGACACGCCCCAGACACGCCGGG
TCCTGCGGGCGGAGGCCCGCGATGCCGGCGCCGCGTGGCTGGAGCTGGAAGCCACTGAAGACCTGCAGCAACACCTCGAC
CGGATCATCTCCCTCCGGGAGGCCGCACGATGA

Upstream 100 bases:

>100_bases
ACGAGATGGTGAACGCCCGCCAGTCCGAGCGGCAGGGCCGACTCATCGACCACGACGAAGAGGGCTCCATGGAGCTCAAG
AAGCGCGAGGGCTACTTCTA

Downstream 100 bases:

>100_bases
GCGCATCCCCTGCCACCCATGCTCCCCCGTTCATCAACGCTCTGCTGGGTGAGAACAAGAGTGCCCTGCTGCTCAAGCTC
GTGGAGGAGATGGACGCCTC

Product: sulfate adenylytransferase large subunit

Products: NA

Alternate protein names: Sulfate adenylyltransferase subunit 1; ATP-sulfurylase large subunit; Sulfate adenylate transferase; SAT; Adenylyl-sulfate kinase; APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase [H]

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MDTGLQQLLDQHASRELLRLVVVGSVDDGKSTLIGRLLYECDGLFEDQISAVRKASAKRTAAAVSVPSEVLVQGLKAAAG
ADGEELDFSLFTDGLRAEREQGITIDVAYRYLSTARRKVIVADTPGHIQYTRNMATGASTADAAVILVDARLGVLPQTRR
HAYIASLLGIPYLAVAVNKMDLTGFDRGAFERIGAELVDFAHALGFEGVRLFPISASRGDNITRPSARTPWHEGGSLLAW
LESLPHQRRQDDAPFRFPVQYVLRPHQDYRGLAGQIASGTVRVGDEIQVHPSGRRTRVAGIDTFDGPLEEAASPASVTLR
LADEVDASRGDVLAHVDQPPLSLHQLDAMLVWFGEQPLDCSRRYLVKQASRTAPAHIERVLWRKELADLSEQPAESLSLN
DIGRVRVVCRRPLLTDPYRDNRRTGAFIVIDALTHDTVAAGMVLGPAEESTKSDVASSLVTQPERRGRLGQPGAIVLLPA
TPDAGSRAFQLERRLFDLGWHVTTTPGDVEVALALAAAGLVALVHTDTPQTRRVLRAEARDAGAAWLELEATEDLQQHLD
RIISLREAAR

Sequences:

>Translated_570_residues
MDTGLQQLLDQHASRELLRLVVVGSVDDGKSTLIGRLLYECDGLFEDQISAVRKASAKRTAAAVSVPSEVLVQGLKAAAG
ADGEELDFSLFTDGLRAEREQGITIDVAYRYLSTARRKVIVADTPGHIQYTRNMATGASTADAAVILVDARLGVLPQTRR
HAYIASLLGIPYLAVAVNKMDLTGFDRGAFERIGAELVDFAHALGFEGVRLFPISASRGDNITRPSARTPWHEGGSLLAW
LESLPHQRRQDDAPFRFPVQYVLRPHQDYRGLAGQIASGTVRVGDEIQVHPSGRRTRVAGIDTFDGPLEEAASPASVTLR
LADEVDASRGDVLAHVDQPPLSLHQLDAMLVWFGEQPLDCSRRYLVKQASRTAPAHIERVLWRKELADLSEQPAESLSLN
DIGRVRVVCRRPLLTDPYRDNRRTGAFIVIDALTHDTVAAGMVLGPAEESTKSDVASSLVTQPERRGRLGQPGAIVLLPA
TPDAGSRAFQLERRLFDLGWHVTTTPGDVEVALALAAAGLVALVHTDTPQTRRVLRAEARDAGAAWLELEATEDLQQHLD
RIISLREAAR
>Mature_570_residues
MDTGLQQLLDQHASRELLRLVVVGSVDDGKSTLIGRLLYECDGLFEDQISAVRKASAKRTAAAVSVPSEVLVQGLKAAAG
ADGEELDFSLFTDGLRAEREQGITIDVAYRYLSTARRKVIVADTPGHIQYTRNMATGASTADAAVILVDARLGVLPQTRR
HAYIASLLGIPYLAVAVNKMDLTGFDRGAFERIGAELVDFAHALGFEGVRLFPISASRGDNITRPSARTPWHEGGSLLAW
LESLPHQRRQDDAPFRFPVQYVLRPHQDYRGLAGQIASGTVRVGDEIQVHPSGRRTRVAGIDTFDGPLEEAASPASVTLR
LADEVDASRGDVLAHVDQPPLSLHQLDAMLVWFGEQPLDCSRRYLVKQASRTAPAHIERVLWRKELADLSEQPAESLSLN
DIGRVRVVCRRPLLTDPYRDNRRTGAFIVIDALTHDTVAAGMVLGPAEESTKSDVASSLVTQPERRGRLGQPGAIVLLPA
TPDAGSRAFQLERRLFDLGWHVTTTPGDVEVALALAAAGLVALVHTDTPQTRRVLRAEARDAGAAWLELEATEDLQQHLD
RIISLREAAR

Specific function: APS kinase catalyzes the synthesis of activated sulfate [H]

COG id: COG2895

COG function: function code P; GTPases - Sulfate adenylate transferase subunit 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI223555963, Length=454, Percent_Identity=28.1938325991189, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI5729864, Length=454, Percent_Identity=28.1938325991189, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI4503471, Length=482, Percent_Identity=27.5933609958506, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI4503475, Length=482, Percent_Identity=27.1784232365145, Blast_Score=159, Evalue=9e-39,
Organism=Homo sapiens, GI194097354, Length=362, Percent_Identity=27.3480662983425, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI194018520, Length=362, Percent_Identity=27.3480662983425, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI194018522, Length=362, Percent_Identity=27.3480662983425, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI46094014, Length=320, Percent_Identity=28.75, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI34147630, Length=249, Percent_Identity=30.5220883534137, Blast_Score=94, Evalue=4e-19,
Organism=Escherichia coli, GI1789108, Length=442, Percent_Identity=47.0588235294118, Blast_Score=387, Evalue=1e-109,
Organism=Escherichia coli, GI1790412, Length=253, Percent_Identity=29.2490118577075, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789737, Length=253, Percent_Identity=29.2490118577075, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI2367247, Length=252, Percent_Identity=27.3809523809524, Blast_Score=82, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17552884, Length=484, Percent_Identity=29.1322314049587, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17569207, Length=484, Percent_Identity=29.1322314049587, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI32566303, Length=477, Percent_Identity=27.4633123689727, Blast_Score=135, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI115532067, Length=302, Percent_Identity=28.8079470198675, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI115532065, Length=302, Percent_Identity=28.8079470198675, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI32566629, Length=459, Percent_Identity=24.6187363834423, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI32566301, Length=163, Percent_Identity=34.3558282208589, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25141371, Length=225, Percent_Identity=26.6666666666667, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17556456, Length=255, Percent_Identity=25.4901960784314, Blast_Score=70, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6325337, Length=459, Percent_Identity=27.2331154684096, Blast_Score=161, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6319594, Length=459, Percent_Identity=27.2331154684096, Blast_Score=161, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6322937, Length=397, Percent_Identity=26.7002518891688, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6320377, Length=455, Percent_Identity=25.2747252747253, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6324761, Length=273, Percent_Identity=31.1355311355311, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24652838, Length=481, Percent_Identity=27.6507276507277, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI17137572, Length=481, Percent_Identity=27.6507276507277, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI45553807, Length=461, Percent_Identity=27.3318872017354, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI45553816, Length=461, Percent_Identity=27.3318872017354, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24651721, Length=461, Percent_Identity=27.3318872017354, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI17864154, Length=461, Percent_Identity=27.3318872017354, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI45550900, Length=443, Percent_Identity=25.7336343115124, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI17137380, Length=457, Percent_Identity=26.0393873085339, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI281363316, Length=265, Percent_Identity=27.9245283018868, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17864358, Length=265, Percent_Identity=27.9245283018868, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19921738, Length=357, Percent_Identity=26.890756302521, Blast_Score=86, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR011779
- InterPro:   IPR009001
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF01583 APS_kinase; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: =2.7.7.4; =2.7.1.25 [H]

Molecular weight: Translated: 62096; Mature: 62096

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTGLQQLLDQHASRELLRLVVVGSVDDGKSTLIGRLLYECDGLFEDQISAVRKASAKRT
CCHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AAAVSVPSEVLVQGLKAAAGADGEELDFSLFTDGLRAEREQGITIDVAYRYLSTARRKVI
HHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHCCCEEEHHHHHHHHHCCEEE
VADTPGHIQYTRNMATGASTADAAVILVDARLGVLPQTRRHAYIASLLGIPYLAVAVNKM
EECCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEHEEECE
DLTGFDRGAFERIGAELVDFAHALGFEGVRLFPISASRGDNITRPSARTPWHEGGSLLAW
ECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHH
LESLPHQRRQDDAPFRFPVQYVLRPHQDYRGLAGQIASGTVRVGDEIQVHPSGRRTRVAG
HHHCCHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCEEEECCEEEECCCCCEEEEEC
IDTFDGPLEEAASPASVTLRLADEVDASRGDVLAHVDQPPLSLHQLDAMLVWFGEQPLDC
CCCCCCCHHHCCCCCEEEEEEHHHCCCCCCCEEEECCCCCCHHHHHHEEEEEECCCCCCH
SRRYLVKQASRTAPAHIERVLWRKELADLSEQPAESLSLNDIGRVRVVCRRPLLTDPYRD
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHEEHEECCCCCCCCCCC
NRRTGAFIVIDALTHDTVAAGMVLGPAEESTKSDVASSLVTQPERRGRLGQPGAIVLLPA
CCCCCEEEEEEECCCCHHHHCEEECCCCHHHHHHHHHHHHCCCHHCCCCCCCCEEEEEEC
TPDAGSRAFQLERRLFDLGWHVTTTPGDVEVALALAAAGLVALVHTDTPQTRRVLRAEAR
CCCCCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHC
DAGAAWLELEATEDLQQHLDRIISLREAAR
CCCCEEEEEECHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDTGLQQLLDQHASRELLRLVVVGSVDDGKSTLIGRLLYECDGLFEDQISAVRKASAKRT
CCHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AAAVSVPSEVLVQGLKAAAGADGEELDFSLFTDGLRAEREQGITIDVAYRYLSTARRKVI
HHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHCCCEEEHHHHHHHHHCCEEE
VADTPGHIQYTRNMATGASTADAAVILVDARLGVLPQTRRHAYIASLLGIPYLAVAVNKM
EECCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEHEEECE
DLTGFDRGAFERIGAELVDFAHALGFEGVRLFPISASRGDNITRPSARTPWHEGGSLLAW
ECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHH
LESLPHQRRQDDAPFRFPVQYVLRPHQDYRGLAGQIASGTVRVGDEIQVHPSGRRTRVAG
HHHCCHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCEEEECCEEEECCCCCEEEEEC
IDTFDGPLEEAASPASVTLRLADEVDASRGDVLAHVDQPPLSLHQLDAMLVWFGEQPLDC
CCCCCCCHHHCCCCCEEEEEEHHHCCCCCCCEEEECCCCCCHHHHHHEEEEEECCCCCCH
SRRYLVKQASRTAPAHIERVLWRKELADLSEQPAESLSLNDIGRVRVVCRRPLLTDPYRD
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHEEHEECCCCCCCCCCC
NRRTGAFIVIDALTHDTVAAGMVLGPAEESTKSDVASSLVTQPERRGRLGQPGAIVLLPA
CCCCCEEEEEEECCCCHHHHCEEECCCCHHHHHHHHHHHHCCCHHCCCCCCCCEEEEEEC
TPDAGSRAFQLERRLFDLGWHVTTTPGDVEVALALAAAGLVALVHTDTPQTRRVLRAEAR
CCCCCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHC
DAGAAWLELEATEDLQQHLDRIISLREAAR
CCCCEEEEEECHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9611812; 10984043 [H]