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The map label for this gene is cysT [H]

Identifier: 108762406

GI number: 108762406

Start: 6030206

End: 6031048

Strand: Reverse

Name: cysT [H]

Synonym: MXAN_4820

Alternate gene names: 108762406

Gene position: 6031048-6030206 (Counterclockwise)

Preceding gene: 108760908

Following gene: 108757696

Centisome position: 65.99

GC content: 68.92

Gene sequence:

>843_bases
ATGTCCCGTCCTACTCGCCACCAGGTGCTCCCGGGGTTCCGTCTGTCGCTGGGCTTCAGTTGGTTCTACCTGGGCCTCAT
CGTCCTCATTCCGCTCTCCAGCCTCTTCCTGCGGACCTTTTCCCTGAGCTGGGAGGAGTTCTGGGGCACCGTGACGACGC
CGCGCGCGCTCGCCGCGTACCGGCTCAGCTTCGGGGCCTCGCTGGCCGCCGCGCTCGCCAACGTCGTCTTCGGCCTGCTG
GTGGCTTGGGTGCTGGTTCGCTACCGCTTCCCCGGCCGCGACGTGCTGGAGTCCCTGGTGGACCTGCCCTTCGCGCTGCC
CACCGCCGTGGCCGGGCTCACGCTCACGACGCTGTTCTCCGCGAAGGGGTGGTACGGCCAGCACCTCGAAGCACTGGGGC
TCAAGGTGGCCTACACGTCCGTGGGCGTGGCCATCGCGCTGACGTTCATCGGGTTGCCCTTCGTGGTGCGCACCGTGCAA
CCCGTGCTGGAGGACATCGACGTGGACGTGGAGGAGGCCGCGGCCACGCTGGGCGCCTCTCCGTGGCAGACCTTCCGACG
CGTCCTCTTTCCCGCGCTCTTCCCCGCGCTGCTCAGCGGCTTCACGCTGGCCTTCGCCCGCGCGCTGGGGGAGTACGGCT
CCGTCGTCTTCATCTCCGGCAACATGCCGCTGCGCACGGAGATTGTCCCGCTGCTCATTATCACCCGGCTGGAGCAGTTC
GACTACGCGGGGGCGACGGCCATCGCCATCGTCATGCTGGGGGCGTCGTTCTCACTGCTGCTGGCCGTCAACCTGCTCCA
TCGCTGGAGCCAGCGCCGGCTGGAAGCCCGGCCGGGAGCGTGA

Upstream 100 bases:

>100_bases
AGTCGCGGGCGACTGGCGGCGGGCGCAGGCCACGCACTTCGCCGACGGCGGCCTCTTCGACCGCATCTACGCGCCCCGCG
CGGACTGAGGACACCCCGCC

Downstream 100 bases:

>100_bases
GCGCCATGCATCCGTCCACCCTTGTCTTGCGCCGAAGCGCGCGCAGTCTGAGCGGCCCGGCGTTCGTCCGTTGGGGGCTC
ATCGGCGCGGCGGTGCTGCT

Product: sulfate ABC transporter permease CysT

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MSRPTRHQVLPGFRLSLGFSWFYLGLIVLIPLSSLFLRTFSLSWEEFWGTVTTPRALAAYRLSFGASLAAALANVVFGLL
VAWVLVRYRFPGRDVLESLVDLPFALPTAVAGLTLTTLFSAKGWYGQHLEALGLKVAYTSVGVAIALTFIGLPFVVRTVQ
PVLEDIDVDVEEAAATLGASPWQTFRRVLFPALFPALLSGFTLAFARALGEYGSVVFISGNMPLRTEIVPLLIITRLEQF
DYAGATAIAIVMLGASFSLLLAVNLLHRWSQRRLEARPGA

Sequences:

>Translated_280_residues
MSRPTRHQVLPGFRLSLGFSWFYLGLIVLIPLSSLFLRTFSLSWEEFWGTVTTPRALAAYRLSFGASLAAALANVVFGLL
VAWVLVRYRFPGRDVLESLVDLPFALPTAVAGLTLTTLFSAKGWYGQHLEALGLKVAYTSVGVAIALTFIGLPFVVRTVQ
PVLEDIDVDVEEAAATLGASPWQTFRRVLFPALFPALLSGFTLAFARALGEYGSVVFISGNMPLRTEIVPLLIITRLEQF
DYAGATAIAIVMLGASFSLLLAVNLLHRWSQRRLEARPGA
>Mature_279_residues
SRPTRHQVLPGFRLSLGFSWFYLGLIVLIPLSSLFLRTFSLSWEEFWGTVTTPRALAAYRLSFGASLAAALANVVFGLLV
AWVLVRYRFPGRDVLESLVDLPFALPTAVAGLTLTTLFSAKGWYGQHLEALGLKVAYTSVGVAIALTFIGLPFVVRTVQP
VLEDIDVDVEEAAATLGASPWQTFRRVLFPALFPALLSGFTLAFARALGEYGSVVFISGNMPLRTEIVPLLIITRLEQFD
YAGATAIAIVMLGASFSLLLAVNLLHRWSQRRLEARPGA

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0555

COG function: function code O; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=270, Percent_Identity=51.4814814814815, Blast_Score=257, Evalue=6e-70,
Organism=Escherichia coli, GI87082099, Length=266, Percent_Identity=35.3383458646617, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1786980, Length=214, Percent_Identity=34.1121495327103, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787369, Length=220, Percent_Identity=27.7272727272727, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786254, Length=196, Percent_Identity=29.5918367346939, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787368, Length=234, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011865
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30605; Mature: 30474

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SRPTRHQVLPGFRLSLGFSWFYLGLIVLIPLSSLFLRTFSLSWEEFWGTVTTPRALAAY
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHH
RLSFGASLAAALANVVFGLLVAWVLVRYRFPGRDVLESLVDLPFALPTAVAGLTLTTLFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
AKGWYGQHLEALGLKVAYTSVGVAIALTFIGLPFVVRTVQPVLEDIDVDVEEAAATLGAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
PWQTFRRVLFPALFPALLSGFTLAFARALGEYGSVVFISGNMPLRTEIVPLLIITRLEQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHH
DYAGATAIAIVMLGASFSLLLAVNLLHRWSQRRLEARPGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2188958; 9205837; 9278503; 2188959 [H]