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The map label for this gene is cysW [H]

Identifier: 108757696

GI number: 108757696

Start: 6029352

End: 6030179

Strand: Reverse

Name: cysW [H]

Synonym: MXAN_4819

Alternate gene names: 108757696

Gene position: 6030179-6029352 (Counterclockwise)

Preceding gene: 108762406

Following gene: 108761031

Centisome position: 65.98

GC content: 68.12

Gene sequence:

>828_bases
TTGCGCCGAAGCGCGCGCAGTCTGAGCGGCCCGGCGTTCGTCCGTTGGGGGCTCATCGGCGCGGCGGTGCTGCTGTTGGG
CGTCTTCCTCATCGTCCCTCTGGTGGCCGTCTTCACCTTCGCCTTCCAGAAGGGCTGGGAGGCCTACGTCGCCGCCCTGA
CGTACCCGACGGCGCTGGCGGCCATGCGGCTGACGCTGCTGGCCGCGGCCATCGCCGTGCCCTTCAACCTCGTCTTCGGC
CTGGCCGCGTCGTGGCTCATCGCGCGGTTCCAATTCCGGGGACGCTCGTTGTTGATGACGCTCATCGACCTGCCCTTCAG
CGTGTCACCCGTCATCGCGGGGCTCATCTTCGTGCTGCTCTTCGGCCGGCAGGGCTGGCTGGGGCCGTGGCTCCTGGACC
ACGACGTCCGCGTCATCTTCGCCGTGCCCGGCATCGTCCTGGCCACGGTGTTCGTCACCTTCCCCTTCGTCGCACGGGAG
GTGCTGCCCGTGATGGAGGCCCAGGGCAGCGATGAAGAAGAGGCGGCGCTGACGCTGGGCGCGAGCGGCTGGCGCACCTT
CCTGACCGTCACGCTGCCGAAGGTGAAGTGGGGCGTGCTTTACGGCGTCATCCTCTGCAACGCGCGAGCAATGGGTGAGT
TCGGCGCCGTGTCCGTGGTGTCCGGCCACGTGCGCGGAGTGACCACGACGCTGCCGCTGCACGCGGAGATTCTCTACAAC
GAGTACGACCTGGCCGGCGCGTTCGCCGTGGCGTCGCTGCTGACGCTGCTCGCGCTCGTGACGTTGGTGGTGAAGAAGTT
CGTGGAGTGGAGGAGTCAGCCGTCATGA

Upstream 100 bases:

>100_bases
TCTCACTGCTGCTGGCCGTCAACCTGCTCCATCGCTGGAGCCAGCGCCGGCTGGAAGCCCGGCCGGGAGCGTGAGCGCCA
TGCATCCGTCCACCCTTGTC

Downstream 100 bases:

>100_bases
GCATCGTCGTCGAACAGCTCGCCCGTCGGTTCAATCGGGGTGGCAGTCCCGCCGTGTCCAAGGTGTCCTTCCAGGCCCCC
GAAGGTGCCATCACCTCGCT

Product: sulfate ABC transporter permease CysW

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MRRSARSLSGPAFVRWGLIGAAVLLLGVFLIVPLVAVFTFAFQKGWEAYVAALTYPTALAAMRLTLLAAAIAVPFNLVFG
LAASWLIARFQFRGRSLLMTLIDLPFSVSPVIAGLIFVLLFGRQGWLGPWLLDHDVRVIFAVPGIVLATVFVTFPFVARE
VLPVMEAQGSDEEEAALTLGASGWRTFLTVTLPKVKWGVLYGVILCNARAMGEFGAVSVVSGHVRGVTTTLPLHAEILYN
EYDLAGAFAVASLLTLLALVTLVVKKFVEWRSQPS

Sequences:

>Translated_275_residues
MRRSARSLSGPAFVRWGLIGAAVLLLGVFLIVPLVAVFTFAFQKGWEAYVAALTYPTALAAMRLTLLAAAIAVPFNLVFG
LAASWLIARFQFRGRSLLMTLIDLPFSVSPVIAGLIFVLLFGRQGWLGPWLLDHDVRVIFAVPGIVLATVFVTFPFVARE
VLPVMEAQGSDEEEAALTLGASGWRTFLTVTLPKVKWGVLYGVILCNARAMGEFGAVSVVSGHVRGVTTTLPLHAEILYN
EYDLAGAFAVASLLTLLALVTLVVKKFVEWRSQPS
>Mature_275_residues
MRRSARSLSGPAFVRWGLIGAAVLLLGVFLIVPLVAVFTFAFQKGWEAYVAALTYPTALAAMRLTLLAAAIAVPFNLVFG
LAASWLIARFQFRGRSLLMTLIDLPFSVSPVIAGLIFVLLFGRQGWLGPWLLDHDVRVIFAVPGIVLATVFVTFPFVARE
VLPVMEAQGSDEEEAALTLGASGWRTFLTVTLPKVKWGVLYGVILCNARAMGEFGAVSVVSGHVRGVTTTLPLHAEILYN
EYDLAGAFAVASLLTLLALVTLVVKKFVEWRSQPS

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=270, Percent_Identity=51.4814814814815, Blast_Score=282, Evalue=2e-77,
Organism=Escherichia coli, GI1788764, Length=212, Percent_Identity=40.5660377358491, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786980, Length=220, Percent_Identity=33.6363636363636, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1787369, Length=163, Percent_Identity=27.6073619631902, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29765; Mature: 29765

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSARSLSGPAFVRWGLIGAAVLLLGVFLIVPLVAVFTFAFQKGWEAYVAALTYPTALA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMRLTLLAAAIAVPFNLVFGLAASWLIARFQFRGRSLLMTLIDLPFSVSPVIAGLIFVLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHH
FGRQGWLGPWLLDHDVRVIFAVPGIVLATVFVTFPFVAREVLPVMEAQGSDEEEAALTLG
HCCCCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEEC
ASGWRTFLTVTLPKVKWGVLYGVILCNARAMGEFGAVSVVSGHVRGVTTTLPLHAEILYN
CCCCEEEEEEEECHHHHHHHHHHHHHCCHHCCCCCCHHHHCCCCCCEEEECCHHHHHHHH
EYDLAGAFAVASLLTLLALVTLVVKKFVEWRSQPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRRSARSLSGPAFVRWGLIGAAVLLLGVFLIVPLVAVFTFAFQKGWEAYVAALTYPTALA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMRLTLLAAAIAVPFNLVFGLAASWLIARFQFRGRSLLMTLIDLPFSVSPVIAGLIFVLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHH
FGRQGWLGPWLLDHDVRVIFAVPGIVLATVFVTFPFVAREVLPVMEAQGSDEEEAALTLG
HCCCCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEEC
ASGWRTFLTVTLPKVKWGVLYGVILCNARAMGEFGAVSVVSGHVRGVTTTLPLHAEILYN
CCCCEEEEEEEECHHHHHHHHHHHHHCCHHCCCCCCHHHHCCCCCCEEEECCHHHHHHHH
EYDLAGAFAVASLLTLLALVTLVVKKFVEWRSQPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]