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The map label for this gene is mrpC [H]

Identifier: 108762359

GI number: 108762359

Start: 6402563

End: 6403309

Strand: Direct

Name: mrpC [H]

Synonym: MXAN_5125

Alternate gene names: 108762359

Gene position: 6402563-6403309 (Clockwise)

Preceding gene: 108758595

Following gene: 108763325

Centisome position: 70.05

GC content: 68.81

Gene sequence:

>747_bases
ATGCACGGTTTCAACCGCCCCCTCGGCCCCATCGGTTCCAACGTCGTGGCGCCGCTGCAGACGACCAGCTCCGGGATGAT
GGTCACCGCCAACAAGCTGGTGCCCGGCCAGGAGGCCATCGACTTCAAGGGCTACTTCAAGGTCGAGTCCTTCCCGCACA
ACTCGACCATCTACCGCCCCGGTGACAACACCGACCGCGTCTACCTGCTGAAGTCCGGCCGCGTGCGCCTGATGCGCATC
GGCAAGAACAGCACCCGCTCCGTGGTGTCCATCCTCCGCCCGGGCGACCTCTTCGGCGAGCTGTTCCGCCCCGAGGGCAC
GCCGATTGAAGAGATGGCCATCGCCGCCGGTGAGGCCGAGGTCTGGAGCATCGAGGGCCGCGACTTCCGCGCCCAGTTGG
AGGCCCGTCCGGCCCTGGCGGTGGACGTGGTCCGCGCCTACGCCGAGCGCGTGCGTGCCCTGCGCAAGCGCGTGCTGGGC
CTGACGTTCAAGGAGGTTCCGGCCCGCCTGGCGGACACCCTGCTCACCCTGGTTGAAGCGCACGGCGAGCGCTGCCCGCA
CGGCGGCGAGACGGACCTGCGCGGCATCACCCAGCAGGACCTCGCGGACCTCGTGGGCGCCTCCCGCTCCTTCGTGTCCA
CGCTCATCAACGAGATGAAGCGCGAGGGCGTGCTCGGCAACGTCGGCCGTATCCTCTGCGTGCGTGACCAGAAGGCCCTG
CGGAAGATCGCCGGCAAGGAGAAGTAG

Upstream 100 bases:

>100_bases
TTTCAATTCCCGCTGGCACGAACCTTGGAGAAGGAAAGTCCCGTTCGCCGCTGAAGCAGACGGCCCGGCTTCCCTACGCT
TCCTTCCCAGGAGTTATGCC

Downstream 100 bases:

>100_bases
TCCGCGCGCCCGCGGCGAACGGGAAGCAGGACACCAGACGGGCCTGACCATGCGCATGCCGCGTGGCCGGGCCCGTGGTG
TTTCCAGCGAACGGCGCTCC

Product: transcriptional regulator MrpC

Products: NA

Alternate protein names: DNA-binding protein VF1; Nitrogen-responsive regulatory protein [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MHGFNRPLGPIGSNVVAPLQTTSSGMMVTANKLVPGQEAIDFKGYFKVESFPHNSTIYRPGDNTDRVYLLKSGRVRLMRI
GKNSTRSVVSILRPGDLFGELFRPEGTPIEEMAIAAGEAEVWSIEGRDFRAQLEARPALAVDVVRAYAERVRALRKRVLG
LTFKEVPARLADTLLTLVEAHGERCPHGGETDLRGITQQDLADLVGASRSFVSTLINEMKREGVLGNVGRILCVRDQKAL
RKIAGKEK

Sequences:

>Translated_248_residues
MHGFNRPLGPIGSNVVAPLQTTSSGMMVTANKLVPGQEAIDFKGYFKVESFPHNSTIYRPGDNTDRVYLLKSGRVRLMRI
GKNSTRSVVSILRPGDLFGELFRPEGTPIEEMAIAAGEAEVWSIEGRDFRAQLEARPALAVDVVRAYAERVRALRKRVLG
LTFKEVPARLADTLLTLVEAHGERCPHGGETDLRGITQQDLADLVGASRSFVSTLINEMKREGVLGNVGRILCVRDQKAL
RKIAGKEK
>Mature_248_residues
MHGFNRPLGPIGSNVVAPLQTTSSGMMVTANKLVPGQEAIDFKGYFKVESFPHNSTIYRPGDNTDRVYLLKSGRVRLMRI
GKNSTRSVVSILRPGDLFGELFRPEGTPIEEMAIAAGEAEVWSIEGRDFRAQLEARPALAVDVVRAYAERVRALRKRVLG
LTFKEVPARLADTLLTLVEAHGERCPHGGETDLRGITQQDLADLVGASRSFVSTLINEMKREGVLGNVGRILCVRDQKAL
RKIAGKEK

Specific function: Has affinity for the xisA upstream region. Binds to a 66 bp region containing three repeats of the consensus recognition sequence 5'-ACATT-3' [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789756, Length=195, Percent_Identity=24.6153846153846, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR022299
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27280; Mature: 27280

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGFNRPLGPIGSNVVAPLQTTSSGMMVTANKLVPGQEAIDFKGYFKVESFPHNSTIYRP
CCCCCCCCCCCCCCCEECCEECCCCEEEEECCCCCCCHHCCCCCEEEEECCCCCCEEECC
GDNTDRVYLLKSGRVRLMRIGKNSTRSVVSILRPGDLFGELFRPEGTPIEEMAIAAGEAE
CCCCCEEEEEECCCEEEEEECCCCHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHCCCCE
VWSIEGRDFRAQLEARPALAVDVVRAYAERVRALRKRVLGLTFKEVPARLADTLLTLVEA
EEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
HGERCPHGGETDLRGITQQDLADLVGASRSFVSTLINEMKREGVLGNVGRILCVRDQKAL
HCCCCCCCCCHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHH
RKIAGKEK
HHHHCCCC
>Mature Secondary Structure
MHGFNRPLGPIGSNVVAPLQTTSSGMMVTANKLVPGQEAIDFKGYFKVESFPHNSTIYRP
CCCCCCCCCCCCCCCEECCEECCCCEEEEECCCCCCCHHCCCCCEEEEECCCCCCEEECC
GDNTDRVYLLKSGRVRLMRIGKNSTRSVVSILRPGDLFGELFRPEGTPIEEMAIAAGEAE
CCCCCEEEEEECCCEEEEEECCCCHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHCCCCE
VWSIEGRDFRAQLEARPALAVDVVRAYAERVRALRKRVLGLTFKEVPARLADTLLTLVEA
EEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
HGERCPHGGETDLRGITQQDLADLVGASRSFVSTLINEMKREGVLGNVGRILCVRDQKAL
HCCCCCCCCCHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHH
RKIAGKEK
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11114927 [H]