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The map label for this gene is hldE [H]

Identifier: 108762352

GI number: 108762352

Start: 5902818

End: 5903804

Strand: Reverse

Name: hldE [H]

Synonym: MXAN_4710

Alternate gene names: 108762352

Gene position: 5903804-5902818 (Counterclockwise)

Preceding gene: 108757784

Following gene: 108759713

Centisome position: 64.59

GC content: 70.62

Gene sequence:

>987_bases
ATGCCGTCGCTCGCCCGCTTGCCGCACGCGTTTGCCCGCCGCAAGGTGTTGCTGGTGGGCGACCTCGTTGCCGACCACTA
CATCTATGGACAGACGGACCGGGTGAGCCGGGAGGCGCCCGTGCTCATCGTCCGCTACGAGTCCGCGGAGGTGAAGCTCG
GAGGTGGCGCCAACGTGGCGGCCAACGTGCGAGCCCTGTCCGGTCAGGTCTCCGCCGTCGGCGCGCTGGGCCAGGACGAG
ATGGGCAAGGAGTTGCGCCGCCTCTGTGCCGAATCCGGCATCCAACTGGACGCGGTGAGCGGTCGCGACATCGAGACGGA
GACGAAGACGCGCATCCTGGCCGGTGGGGTGAGCACCACGCGGCAGCAGATGTTGCGGCTGGACCGAGGCCAGCGAGGCG
CGCTCCCCCCGAAGATGCGCAAGGCGCTGGCGCGGCAGGTCGAAGCCTCTGCCCAGGACGCGGACGCGGTGGTGGTGTCC
GACTACGGCGCGGGTGTGCTGGGGGACGAGGTGCGCGATGTGCTGCGTCGCCTGGCCGCGGACGGCATGCCCGTGTGTGT
GGACAGCCGCTATGCCCTGTCATCCTTCTCGGGACTCACGGTCTGCAAGCCCAACGAGCCGGAGCTGGAGGCGCTCGCGG
GGCGGCCCGTGCGGACCCAGGAGGACATGCTGGAGGCGGGGCACGCCGCGTTGAAGCGACTGGAGTGCCGCGCGCTCCTG
GTGACGCGAGGCCGCCATGGCATGGCGCTCTTCGATGCGGACGGGGGCGTGGACCTCATCCCCGTCCATGGCGCGAAGGC
GGCGGTGGATGTGACGGGCGCGGGAGACACGGTGATTGCGACGTTTGCCCTGGCGCTGGCCGCGAAGGCCTCGCTCGGCG
ATGCGGCGCGGCTGGCGAACGTGGCGGGCTCGTTGGTGGTGCAGAAGCCGGGCACCGCGACGGTGTCCCGCGATGAACTG
CTCGAAGAGCTTCGGAGCGCGAGATGA

Upstream 100 bases:

>100_bases
CGGCGGGCGCTCGGACTGGAGGATGCTCCGCGCGGCTTGTGAGGTGGGGGCGGCTGTGGGACAAACCGCCGCCATGGCCG
CAGTCTCGCCCGTTCGTTCG

Downstream 100 bases:

>100_bases
GCACCCTCGAGAAAATCCAATCGCTCGCGAAGGTGGCGGAGGAGCGTGAGCGCTGGCGGGCCGAAGGGCGCACGGTGGCG
CTGGCCAATGGCGTCTTCGA

Product: D-beta-D-heptose 7-phosphate kinase

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MPSLARLPHAFARRKVLLVGDLVADHYIYGQTDRVSREAPVLIVRYESAEVKLGGGANVAANVRALSGQVSAVGALGQDE
MGKELRRLCAESGIQLDAVSGRDIETETKTRILAGGVSTTRQQMLRLDRGQRGALPPKMRKALARQVEASAQDADAVVVS
DYGAGVLGDEVRDVLRRLAADGMPVCVDSRYALSSFSGLTVCKPNEPELEALAGRPVRTQEDMLEAGHAALKRLECRALL
VTRGRHGMALFDADGGVDLIPVHGAKAAVDVTGAGDTVIATFALALAAKASLGDAARLANVAGSLVVQKPGTATVSRDEL
LEELRSAR

Sequences:

>Translated_328_residues
MPSLARLPHAFARRKVLLVGDLVADHYIYGQTDRVSREAPVLIVRYESAEVKLGGGANVAANVRALSGQVSAVGALGQDE
MGKELRRLCAESGIQLDAVSGRDIETETKTRILAGGVSTTRQQMLRLDRGQRGALPPKMRKALARQVEASAQDADAVVVS
DYGAGVLGDEVRDVLRRLAADGMPVCVDSRYALSSFSGLTVCKPNEPELEALAGRPVRTQEDMLEAGHAALKRLECRALL
VTRGRHGMALFDADGGVDLIPVHGAKAAVDVTGAGDTVIATFALALAAKASLGDAARLANVAGSLVVQKPGTATVSRDEL
LEELRSAR
>Mature_327_residues
PSLARLPHAFARRKVLLVGDLVADHYIYGQTDRVSREAPVLIVRYESAEVKLGGGANVAANVRALSGQVSAVGALGQDEM
GKELRRLCAESGIQLDAVSGRDIETETKTRILAGGVSTTRQQMLRLDRGQRGALPPKMRKALARQVEASAQDADAVVVSD
YGAGVLGDEVRDVLRRLAADGMPVCVDSRYALSSFSGLTVCKPNEPELEALAGRPVRTQEDMLEAGHAALKRLECRALLV
TRGRHGMALFDADGGVDLIPVHGAKAAVDVTGAGDTVIATFALALAAKASLGDAARLANVAGSLVVQKPGTATVSRDELL
EELRSAR

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=322, Percent_Identity=36.9565217391304, Blast_Score=167, Evalue=7e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.-

Molecular weight: Translated: 34549; Mature: 34418

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLARLPHAFARRKVLLVGDLVADHYIYGQTDRVSREAPVLIVRYESAEVKLGGGANVA
CCCHHHHHHHHHHCEEEEEEHHHHHCEEECCCCCCCCCCCEEEEEECCCEEEECCCCCCE
ANVRALSGQVSAVGALGQDEMGKELRRLCAESGIQLDAVSGRDIETETKTRILAGGVSTT
EEHHHHCCCHHHHCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHEEEECCCHHH
RQQMLRLDRGQRGALPPKMRKALARQVEASAQDADAVVVSDYGAGVLGDEVRDVLRRLAA
HHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
DGMPVCVDSRYALSSFSGLTVCKPNEPELEALAGRPVRTQEDMLEAGHAALKRLECRALL
CCCCEEECCCHHHHCCCCEEEECCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEE
VTRGRHGMALFDADGGVDLIPVHGAKAAVDVTGAGDTVIATFALALAAKASLGDAARLAN
EECCCCCEEEEECCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHH
VAGSLVVQKPGTATVSRDELLEELRSAR
HHCCEEEECCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
PSLARLPHAFARRKVLLVGDLVADHYIYGQTDRVSREAPVLIVRYESAEVKLGGGANVA
CCHHHHHHHHHHCEEEEEEHHHHHCEEECCCCCCCCCCCEEEEEECCCEEEECCCCCCE
ANVRALSGQVSAVGALGQDEMGKELRRLCAESGIQLDAVSGRDIETETKTRILAGGVSTT
EEHHHHCCCHHHHCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHEEEECCCHHH
RQQMLRLDRGQRGALPPKMRKALARQVEASAQDADAVVVSDYGAGVLGDEVRDVLRRLAA
HHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
DGMPVCVDSRYALSSFSGLTVCKPNEPELEALAGRPVRTQEDMLEAGHAALKRLECRALL
CCCCEEECCCHHHHCCCCEEEECCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEE
VTRGRHGMALFDADGGVDLIPVHGAKAAVDVTGAGDTVIATFALALAAKASLGDAARLAN
EECCCCCEEEEECCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHH
VAGSLVVQKPGTATVSRDELLEELRSAR
HHCCEEEECCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA