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The map label for this gene is lpxK [H]

Identifier: 108757784

GI number: 108757784

Start: 5903863

End: 5905056

Strand: Reverse

Name: lpxK [H]

Synonym: MXAN_4711

Alternate gene names: 108757784

Gene position: 5905056-5903863 (Counterclockwise)

Preceding gene: 108763971

Following gene: 108762352

Centisome position: 64.61

GC content: 70.69

Gene sequence:

>1194_bases
GTGACGTCCCCGGATGCCCCCACCGCCATCGAGCGGGTGTTCTACCCGCCGTCGCCGGAGCCCTGGGGCCGCCGCGCCCT
GCTGTCGCCGCTCACGTTGCTGTCGTGGACGTACGCGGCCGCGGTGCATGTACGGGGAGCGCTCTTCGACGCGGGACTGC
TGCGCGCGGAGCGGGTGGAGGGGCTCAAGGTCATCTCCGTGGGCAACGTCAACGTGGGGGGTACGGGCAAGACGCCCGCG
GTGCTCCATCTGGCGGAGCAGTTGGTCCAAGCGGGCCGGAAGGTGGGCATCCTGACGCGCGGTTATGGCCGCGCCTCGCG
TGAGCCGCTGACCTTCATCGGGACGGAGCCGCTTCCTTCCTCGGACCTCGCGGGTGATGAGCCGCTCCTGCTGGCGCGTC
GCTGTCCCCAGGTCCGGCTCTTCGTCGGCTCGGACCGAGTCGCGAGTGCCTACCGTGCGCGGGACGATTTCAGCCTGGAC
ACGGTGCTGCTGGACGATGGGTTCCAGCATCGCCGCCTCGCGCGAGACGAGGACTTCGTGGTCGTGGATGAGTCGGTGGG
GCTGGGCAACGGCCACATGCTTCCCAGGGGGCCGCTGCGTGAGCCCCCGGCGTCACTCCGCCGCGCGACGCTTTTCTGGC
TCAGGGCACCCGCCACGGCTTCGGATGCTGCTGTGCTCCCCGTCATGAGGCCCGAGGACACGCGCACGCCCCAATCCACC
ACGCACCTCCTGGTGCCGACAGAGGCGCGGTCGGAGCGTTTCTCTGACACGCTCGGCGGGTGGTTGCCCTCGAGCCCGGG
GATTCCCAGGGTGAGGACTCGCTATCGGCCCACGGCCTGGGTGGACCCGGAGGGCAACCTTCATCCCGTGACGGCGCTCA
CGGGACAGCCCGTGTTCGCTCTGGCGGGCCTTGCCCGGCCGGGGGGCTTCCTGAAGACCCTGCAGTCGCTCGGGACGGAC
GTGCGCGATGCCGCGTTGTTTCCGGACCACCATCGCTTCACCGCGGACGAACTGCGCGACGTCCAGGCGCGAGCGGTGCG
GCTGGGGGCCCGGGTGGTGACGACGGAAAAGGACGCGGTGCGTCTACCCCAGGGCTTCGAGGCCTGGGTGGTCCGCCTGG
GGGTCGAGGTTCTGGAAGGCGAGTCCCATCTGCGGCGGGCGCTCGGACTGGAGGATGCTCCGCGCGGCTTGTGA

Upstream 100 bases:

>100_bases
CCGCGGCGCTGTCCGACCAGCGGGCGCCCGTGCGGCACCCGACGAACGAGCAGATTGCCGCGGAGGTCCTCGCGCTCTAC
GCGCGAGCGAGGCGCACCCC

Downstream 100 bases:

>100_bases
GGTGGGGGCGGCTGTGGGACAAACCGCCGCCATGGCCGCAGTCTCGCCCGTTCGTTCGATGCCGTCGCTCGCCCGCTTGC
CGCACGCGTTTGCCCGCCGC

Product: tetraacyldisaccharide 4'-kinase

Products: NA

Alternate protein names: Lipid A 4'-kinase [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MTSPDAPTAIERVFYPPSPEPWGRRALLSPLTLLSWTYAAAVHVRGALFDAGLLRAERVEGLKVISVGNVNVGGTGKTPA
VLHLAEQLVQAGRKVGILTRGYGRASREPLTFIGTEPLPSSDLAGDEPLLLARRCPQVRLFVGSDRVASAYRARDDFSLD
TVLLDDGFQHRRLARDEDFVVVDESVGLGNGHMLPRGPLREPPASLRRATLFWLRAPATASDAAVLPVMRPEDTRTPQST
THLLVPTEARSERFSDTLGGWLPSSPGIPRVRTRYRPTAWVDPEGNLHPVTALTGQPVFALAGLARPGGFLKTLQSLGTD
VRDAALFPDHHRFTADELRDVQARAVRLGARVVTTEKDAVRLPQGFEAWVVRLGVEVLEGESHLRRALGLEDAPRGL

Sequences:

>Translated_397_residues
MTSPDAPTAIERVFYPPSPEPWGRRALLSPLTLLSWTYAAAVHVRGALFDAGLLRAERVEGLKVISVGNVNVGGTGKTPA
VLHLAEQLVQAGRKVGILTRGYGRASREPLTFIGTEPLPSSDLAGDEPLLLARRCPQVRLFVGSDRVASAYRARDDFSLD
TVLLDDGFQHRRLARDEDFVVVDESVGLGNGHMLPRGPLREPPASLRRATLFWLRAPATASDAAVLPVMRPEDTRTPQST
THLLVPTEARSERFSDTLGGWLPSSPGIPRVRTRYRPTAWVDPEGNLHPVTALTGQPVFALAGLARPGGFLKTLQSLGTD
VRDAALFPDHHRFTADELRDVQARAVRLGARVVTTEKDAVRLPQGFEAWVVRLGVEVLEGESHLRRALGLEDAPRGL
>Mature_396_residues
TSPDAPTAIERVFYPPSPEPWGRRALLSPLTLLSWTYAAAVHVRGALFDAGLLRAERVEGLKVISVGNVNVGGTGKTPAV
LHLAEQLVQAGRKVGILTRGYGRASREPLTFIGTEPLPSSDLAGDEPLLLARRCPQVRLFVGSDRVASAYRARDDFSLDT
VLLDDGFQHRRLARDEDFVVVDESVGLGNGHMLPRGPLREPPASLRRATLFWLRAPATASDAAVLPVMRPEDTRTPQSTT
HLLVPTEARSERFSDTLGGWLPSSPGIPRVRTRYRPTAWVDPEGNLHPVTALTGQPVFALAGLARPGGFLKTLQSLGTDV
RDAALFPDHHRFTADELRDVQARAVRLGARVVTTEKDAVRLPQGFEAWVVRLGVEVLEGESHLRRALGLEDAPRGL

Specific function: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) [H]

COG id: COG1663

COG function: function code M; Tetraacyldisaccharide-1-P 4'-kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxK family [H]

Homologues:

Organism=Escherichia coli, GI1787144, Length=356, Percent_Identity=31.4606741573034, Blast_Score=111, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003758 [H]

Pfam domain/function: PF02606 LpxK [H]

EC number: =2.7.1.130 [H]

Molecular weight: Translated: 43233; Mature: 43102

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPDAPTAIERVFYPPSPEPWGRRALLSPLTLLSWTYAAAVHVRGALFDAGLLRAERVE
CCCCCCCHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GLKVISVGNVNVGGTGKTPAVLHLAEQLVQAGRKVGILTRGYGRASREPLTFIGTEPLPS
CEEEEEECCEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCCCC
SDLAGDEPLLLARRCPQVRLFVGSDRVASAYRARDDFSLDTVLLDDGFQHRRLARDEDFV
CCCCCCCCCHHHHCCCEEEEEECCCHHHHHHHCCCCCCEEEEEECCCHHHHHHCCCCCEE
VVDESVGLGNGHMLPRGPLREPPASLRRATLFWLRAPATASDAAVLPVMRPEDTRTPQST
EEECCCCCCCCCCCCCCCCCCCHHHHHHEEEEEEECCCCCCCCEEEECCCCCCCCCCCCC
THLLVPTEARSERFSDTLGGWLPSSPGIPRVRTRYRPTAWVDPEGNLHPVTALTGQPVFA
EEEEEECHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCEEECCCCCEEEEEEECCCCHHH
LAGLARPGGFLKTLQSLGTDVRDAALFPDHHRFTADELRDVQARAVRLGARVVTTEKDAV
HHCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCHH
RLPQGFEAWVVRLGVEVLEGESHLRRALGLEDAPRGL
CCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TSPDAPTAIERVFYPPSPEPWGRRALLSPLTLLSWTYAAAVHVRGALFDAGLLRAERVE
CCCCCCHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GLKVISVGNVNVGGTGKTPAVLHLAEQLVQAGRKVGILTRGYGRASREPLTFIGTEPLPS
CEEEEEECCEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCCCC
SDLAGDEPLLLARRCPQVRLFVGSDRVASAYRARDDFSLDTVLLDDGFQHRRLARDEDFV
CCCCCCCCCHHHHCCCEEEEEECCCHHHHHHHCCCCCCEEEEEECCCHHHHHHCCCCCEE
VVDESVGLGNGHMLPRGPLREPPASLRRATLFWLRAPATASDAAVLPVMRPEDTRTPQST
EEECCCCCCCCCCCCCCCCCCCHHHHHHEEEEEEECCCCCCCCEEEECCCCCCCCCCCCC
THLLVPTEARSERFSDTLGGWLPSSPGIPRVRTRYRPTAWVDPEGNLHPVTALTGQPVFA
EEEEEECHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCEEECCCCCEEEEEEECCCCHHH
LAGLARPGGFLKTLQSLGTDVRDAALFPDHHRFTADELRDVQARAVRLGARVVTTEKDAV
HHCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCHH
RLPQGFEAWVVRLGVEVLEGESHLRRALGLEDAPRGL
CCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA