BacMap

Definition	Myxococcus xanthus DK 1622 chromosome, complete genome.
Accession	NC_008095
Length	9,139,763

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The map label for this gene is yqjQ [H]

Identifier: 108762268

GI number: 108762268

Start: 1052762

End: 1053544

Strand: Direct

Name: yqjQ [H]

Synonym: MXAN_0923

Alternate gene names: 108762268

Gene position: 1052762-1053544 (Clockwise)

Preceding gene: 108763962

Following gene: 108762234

Centisome position: 11.52

GC content: 69.99

Gene sequence:

>783_bases
ATGTCGCGGAAAGTGGCGCTCATCACCGGGGCTTCGGCGGGTTTGGGAGAGCAGTTCGCACACCTGTTCGCGAAGGACGG
ACACGACGTCATCCTGGTCGCGCGCAGCGCGACTCGGCTGGAGGCGCTGGCGGCGAAGCTGGAGCAGGCCCATGGCGTGA
AGGCACACGTCTTCCCAGCGGACCTGGGCCGGCCGGAGTCTCCCGAGCAGCTCTTCGAGGCCGTGCGCGCGAAGGGGCTG
GCGGTGGAGTTCCTGGTGAACAACGCGGGCTTCGGTTCGTGCGGTCCCTTCCTGGCGCAGGACCTGGCGCGGGAGGCGGA
GATGGTGGAGGTCAACTGCACCGCCCTCCTGAAGCTGTCGCACCTGTTCGCGCGGCCCATGCAGGAGCGGGGCAGCGGGC
GCATCCTCAACGTCGCCTCCACCGCGGCCTTTCAGCCCGGCCCCTTCATGGCCACGTACTTCGCGACTAAGGCCTTCGTG
GTGTCCCTGTCGGAGGCGCTGGCGCACGAACTGAAGGGCACGGGCGTGACGGTGACGTGCCACTGTCCGGGTGCCACGCA
CACGGAGTTCACCCAGCGCGCGGGCAACGGCCAGACGCGGCTGTTCCAGCAGCCGGGCGTGGCCAAGGCGGAGGACGTGG
CCGCCCATGCCTACGCGATGATGATGCGCGGCCGGGTGCTCTCCATCCACGGACTGCTCAACTGGGTGGGGACCCTGGGC
GTGCGCTTCAGCCCGCGCGTGGCGGTGCGCGCGCTCGCGGCCAGCCTCAACCAGCAGGGCTGA

Upstream 100 bases:

>100_bases
CGAGGCCGCCCGTCAGTCCCACCTGCCGGGGTGGATGAATGTTGGCGGGACCGCCACGCTCGAGCCGCTCGGCTATAACG
CGACACCTGGAGGAAACATC

Downstream 100 bases:

>100_bases
GGCTGGCCTCCGCGGCGGCGCCGCTCAGTTGTACGTCGCGGAGAAGACGAGCGACACGTTGGTGACGTTCCAGCTATCGC
TGTTCGACTCGTTCCGGATG

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MSRKVALITGASAGLGEQFAHLFAKDGHDVILVARSATRLEALAAKLEQAHGVKAHVFPADLGRPESPEQLFEAVRAKGL
AVEFLVNNAGFGSCGPFLAQDLAREAEMVEVNCTALLKLSHLFARPMQERGSGRILNVASTAAFQPGPFMATYFATKAFV
VSLSEALAHELKGTGVTVTCHCPGATHTEFTQRAGNGQTRLFQQPGVAKAEDVAAHAYAMMMRGRVLSIHGLLNWVGTLG
VRFSPRVAVRALAASLNQQG

Sequences:

>Translated_260_residues
MSRKVALITGASAGLGEQFAHLFAKDGHDVILVARSATRLEALAAKLEQAHGVKAHVFPADLGRPESPEQLFEAVRAKGL
AVEFLVNNAGFGSCGPFLAQDLAREAEMVEVNCTALLKLSHLFARPMQERGSGRILNVASTAAFQPGPFMATYFATKAFV
VSLSEALAHELKGTGVTVTCHCPGATHTEFTQRAGNGQTRLFQQPGVAKAEDVAAHAYAMMMRGRVLSIHGLLNWVGTLG
VRFSPRVAVRALAASLNQQG
>Mature_259_residues
SRKVALITGASAGLGEQFAHLFAKDGHDVILVARSATRLEALAAKLEQAHGVKAHVFPADLGRPESPEQLFEAVRAKGLA
VEFLVNNAGFGSCGPFLAQDLAREAEMVEVNCTALLKLSHLFARPMQERGSGRILNVASTAAFQPGPFMATYFATKAFVV
SLSEALAHELKGTGVTVTCHCPGATHTEFTQRAGNGQTRLFQQPGVAKAEDVAAHAYAMMMRGRVLSIHGLLNWVGTLGV
RFSPRVAVRALAASLNQQG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4557649, Length=189, Percent_Identity=32.8042328042328, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI7705855, Length=193, Percent_Identity=29.5336787564767, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI109715829, Length=223, Percent_Identity=30.9417040358744, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI32483357, Length=197, Percent_Identity=29.4416243654822, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI33667109, Length=198, Percent_Identity=29.7979797979798, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI5031737, Length=198, Percent_Identity=29.7979797979798, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI226371731, Length=192, Percent_Identity=28.125, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI210032110, Length=234, Percent_Identity=26.9230769230769, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI142976729, Length=239, Percent_Identity=29.7071129707113, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI7706318, Length=202, Percent_Identity=26.7326732673267, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI126723191, Length=185, Percent_Identity=28.6486486486486, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI40254992, Length=189, Percent_Identity=26.984126984127, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI223718074, Length=204, Percent_Identity=30.8823529411765, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=27.1794871794872, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787335, Length=198, Percent_Identity=31.3131313131313, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1787820, Length=220, Percent_Identity=31.3636363636364, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082100, Length=193, Percent_Identity=31.0880829015544, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082160, Length=188, Percent_Identity=28.1914893617021, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788459, Length=187, Percent_Identity=31.5508021390374, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790717, Length=192, Percent_Identity=28.125, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786701, Length=208, Percent_Identity=27.8846153846154, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1787526, Length=195, Percent_Identity=25.1282051282051, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789378, Length=207, Percent_Identity=28.9855072463768, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787905, Length=189, Percent_Identity=30.6878306878307, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1789208, Length=193, Percent_Identity=26.9430051813472, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=197, Percent_Identity=30.4568527918782, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=199, Percent_Identity=30.1507537688442, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=203, Percent_Identity=30.0492610837438, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=206, Percent_Identity=29.126213592233, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=205, Percent_Identity=31.219512195122, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=203, Percent_Identity=29.5566502463054, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=204, Percent_Identity=28.4313725490196, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=201, Percent_Identity=29.3532338308458, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=194, Percent_Identity=28.8659793814433, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=198, Percent_Identity=28.7878787878788, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=192, Percent_Identity=29.1666666666667, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=198, Percent_Identity=29.7979797979798, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=209, Percent_Identity=31.1004784688995, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=200, Percent_Identity=27.5, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319635, Length=188, Percent_Identity=31.3829787234043, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6323882, Length=226, Percent_Identity=30.9734513274336, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24640442, Length=194, Percent_Identity=29.3814432989691, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24584752, Length=190, Percent_Identity=30.5263157894737, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21357041, Length=195, Percent_Identity=31.2820512820513, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24584744, Length=199, Percent_Identity=29.1457286432161, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28574402, Length=199, Percent_Identity=29.1457286432161, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28571526, Length=192, Percent_Identity=30.7291666666667, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21358495, Length=197, Percent_Identity=30.9644670050761, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644339, Length=192, Percent_Identity=29.1666666666667, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355319, Length=198, Percent_Identity=28.2828282828283, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI116007236, Length=220, Percent_Identity=29.0909090909091, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24584748, Length=181, Percent_Identity=27.6243093922652, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI161076933, Length=181, Percent_Identity=27.6243093922652, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI23397609, Length=195, Percent_Identity=27.6923076923077, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639444, Length=188, Percent_Identity=29.7872340425532, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24580925, Length=204, Percent_Identity=29.9019607843137, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI116007238, Length=185, Percent_Identity=28.6486486486486, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24641232, Length=197, Percent_Identity=27.4111675126904, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24649181, Length=230, Percent_Identity=27.8260869565217, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28571387, Length=196, Percent_Identity=26.530612244898, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 27617; Mature: 27486

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKVALITGASAGLGEQFAHLFAKDGHDVILVARSATRLEALAAKLEQAHGVKAHVFPA
CCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEC
DLGRPESPEQLFEAVRAKGLAVEFLVNNAGFGSCGPFLAQDLAREAEMVEVNCTALLKLS
CCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHEEEECHHHHHHHH
HLFARPMQERGSGRILNVASTAAFQPGPFMATYFATKAFVVSLSEALAHELKGTGVTVTC
HHHHHHHHHCCCCCEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
HCPGATHTEFTQRAGNGQTRLFQQPGVAKAEDVAAHAYAMMMRGRVLSIHGLLNWVGTLG
ECCCCCCHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
VRFSPRVAVRALAASLNQQG
CCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SRKVALITGASAGLGEQFAHLFAKDGHDVILVARSATRLEALAAKLEQAHGVKAHVFPA
CCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEC
DLGRPESPEQLFEAVRAKGLAVEFLVNNAGFGSCGPFLAQDLAREAEMVEVNCTALLKLS
CCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHEEEECHHHHHHHH
HLFARPMQERGSGRILNVASTAAFQPGPFMATYFATKAFVVSLSEALAHELKGTGVTVTC
HHHHHHHHHCCCCCEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
HCPGATHTEFTQRAGNGQTRLFQQPGVAKAEDVAAHAYAMMMRGRVLSIHGLLNWVGTLG
ECCCCCCHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
VRFSPRVAVRALAASLNQQG
CCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]