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The map label for this gene is dsbD [H]

Identifier: 108761980

GI number: 108761980

Start: 343105

End: 345429

Strand: Direct

Name: dsbD [H]

Synonym: MXAN_0289

Alternate gene names: 108761980

Gene position: 343105-345429 (Clockwise)

Preceding gene: 108761535

Following gene: 108760975

Centisome position: 3.75

GC content: 72.17

Gene sequence:

>2325_bases
ATGACGCATCAGCAGTCCAAGAGGCTCGGCGTTGTTGGTGGAATCGGACTGCTGCTGGTGGCGGCGGTCGCGTGGGCGGA
CCTGCCCGCGTCGGCGGTGGCATCGAGCGCGCCGGACGAAGGCGACCCTCGCATCGAGGGTGCCCTCCTGGTGGACGCCA
CCGAGGTGAAGCCGGGAGACACCTTCCGCGTGGGCGTGCGCTTCCGGTTGGATCCAGGCTGGCACGTCTACTGGAAGAAC
CCGGGCGACTCCGGCTTGGAGACGGAAGTGGCGTGGGACACGCCCGGCGTCACCGTGGGGCCGCTGCAGTGGCCCTTCCC
GCAGACGTTCCGCACGCCCGACGGCTTCATCACCACCCATGGCTATGACGGTGAGGCCATCCTCATCGCCGACGCGAAGG
CCGTGGAAGGGCCCTCCACGGGCCTGCTGACGGTGTCCGCCGCCGTGGAAGCGCTGGTGTGCGAGGTGCACTGCATCCCC
GCGGAGCTGATGCTGACGCGCTCCATCCCCCTGGGTCCCCAGACGGTGCGCGACGCCGAGACAGCGGCTGTCTTCGACAC
CGAGCTGGCCAAGGTGCCCCGTCCCGCCAAGGACAGCGGCCCCGCGGCGACGGTGGCGCTGGATGCGCCGCAGCTCACCG
CGGGCCAGGATTTCACCGGCACCCTCACCCTGACGGCCCCGGGCGGCGCGGCGGTGCCCGCGGTGGAAGGTGACTTCTTC
GTCGCCGACCGCATCCCCGGCGTCGTGCGCGTGGGGTTGGCCTCGGACGGTCCGGGCCGCTTCAAACTCAAGGGCAAGGC
GGAGCCGGACGCGCAGGCGTCGGCGCCGGACCTGACGGGCGTGCTGCGCCTGGGCACGGCGGCCACGGGCTACCAGTACC
TCGAGGTGACGGCGCCGCTGGCCCCCTTGGTGGCGGCCGGTGGCGCGGCTGGGACGCCGGCCGTGGTGAAGCCGCCGTCG
GTGAAGGACAGCATCGCGGCGGTGAAGCCGGTGGGCGCCGCCATCGCCACGCCGCCCGCGGCCGAGTCGTCCATGGGCCT
GGGGCTGGCGCTGGTGTTCGCCTTCTTCGGTGGCGCGCTGCTCAACCTGATGCCGTGCGTGTTCCCCGTGCTGGCGCTCA
AGGCCTACGGCTTCACGCGCATGGTGCAGCAGGAGCAGGGCCGCGTCGGCGCGCATGCGGCGGCCTACGCGGCGGGCATC
ATCGGCACCATGCTGCTGCTGGCCAGCGTCGTGCTGGCGGTGCGCGCGGGTGGCGCGAGCGTGGGCTGGGGCTTCCAGTT
CCAGGAGCCGCTCTTCGTCGCGGGTGTGTGCGCGGTGTTGGTCGCCTTCGCGCTCAACCTCTTCGGTGTCTTCAACGTGG
GCCTGGACGGCACGGCGCTGGCGGGCAAGGTGGACCAGAGCCACGGCCTGATGCACAGCGCTGGCGAGGGCGTGCTGGCC
GTGGTGCTGGCCACGCCGTGCTCGGCGCCGCTGCTGGGCACCGCGGTGGGCTTCGCCTTCGCGGCGGGCCCCATGACGGT
GCTGGCCGTCTTCACCGCGCTGGGCCTGGGGCTCGCGCTGCCCTTCTGTGTGCTGGTGCTGGTGCCCGGGCTGGCGAAGA
AGCTGCCCAAGCCGGGCGCGTGGATGGAGCGCTTCAAGCAGGTGCTGGGCTTCGCGCTGCTGGCCACCACTGTCTGGCTG
GTGTGGGTAATGGGCGGGCTGGCCGGCGTGGACGGCATGGCGCGGCTGCTGGCGTTCCTGGTCGCGGTGGGGCTCGTCAC
GTGGCTGTACGGTCAGGGGCAGGCGCAGGACGGTGTGCGCAAGCTGGCCACCGTGGCGGTGGCCGCGGGCGTGCTGGTGG
CGTCAGGGCTGCTGACGTTGCGTTTCGATGACCAGGACCCCGTGGAGGCGCCTCGGGTCGGGTCCACGGTGGCGCAGGCG
CAGCCGTGGAGCGCGGACGCGGTGAACGCGGCGCTGGCGGCGGGCCAGCCGGTGTTCATCGACTTCACTGCGGACTGGTG
CCTCACCTGCAAGTTCAACGAGCGCACCGTGCTGTCCACCGACGAGGTGCGGGACGCCTTCAAGAAGCACCAGGTGGCCT
TCTTCATCGCGGACTGGACGCGCCGGGACGCGAGCATCACCACCAAGCTGGCCGAGCACGGCCGGGCCGGTGTGCCCATG
TACCTGGTGCTGAGCCCGGGCGCCCCCGACAAGCCGGAGGTGCTGCCGGAGTTGCTCACGCCGGGCGTGGTGACGGACGC
CGTGACGCGCGCGGCGGCGTGTGCACCCTCGAAGCTGGGCAACGGCGCGAACGTCCTCTGCGCCGCGGGTTTCCCGAGTC
ACTGA

Upstream 100 bases:

>100_bases
TCATGCGAGGGGAATGCCCGCCTGCCCGGATGGTTCACTGTGCTCGGAGGCACGTGTCTGCCGCTGGCGGGCCGGCCTCC
TCTGGGTTAACGGGAGTCGC

Downstream 100 bases:

>100_bases
AGTCGCGCTGTCTTCCCCGCAGTCCCCAAAACGCTGGAGGAACGCCATGAAGCAGGTCTTCACCGCACTCGCGCTGGGCA
CGTTACTCATCGGGGCGCCC

Product: hypothetical protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 774; Mature: 773

Protein sequence:

>774_residues
MTHQQSKRLGVVGGIGLLLVAAVAWADLPASAVASSAPDEGDPRIEGALLVDATEVKPGDTFRVGVRFRLDPGWHVYWKN
PGDSGLETEVAWDTPGVTVGPLQWPFPQTFRTPDGFITTHGYDGEAILIADAKAVEGPSTGLLTVSAAVEALVCEVHCIP
AELMLTRSIPLGPQTVRDAETAAVFDTELAKVPRPAKDSGPAATVALDAPQLTAGQDFTGTLTLTAPGGAAVPAVEGDFF
VADRIPGVVRVGLASDGPGRFKLKGKAEPDAQASAPDLTGVLRLGTAATGYQYLEVTAPLAPLVAAGGAAGTPAVVKPPS
VKDSIAAVKPVGAAIATPPAAESSMGLGLALVFAFFGGALLNLMPCVFPVLALKAYGFTRMVQQEQGRVGAHAAAYAAGI
IGTMLLLASVVLAVRAGGASVGWGFQFQEPLFVAGVCAVLVAFALNLFGVFNVGLDGTALAGKVDQSHGLMHSAGEGVLA
VVLATPCSAPLLGTAVGFAFAAGPMTVLAVFTALGLGLALPFCVLVLVPGLAKKLPKPGAWMERFKQVLGFALLATTVWL
VWVMGGLAGVDGMARLLAFLVAVGLVTWLYGQGQAQDGVRKLATVAVAAGVLVASGLLTLRFDDQDPVEAPRVGSTVAQA
QPWSADAVNAALAAGQPVFIDFTADWCLTCKFNERTVLSTDEVRDAFKKHQVAFFIADWTRRDASITTKLAEHGRAGVPM
YLVLSPGAPDKPEVLPELLTPGVVTDAVTRAAACAPSKLGNGANVLCAAGFPSH

Sequences:

>Translated_774_residues
MTHQQSKRLGVVGGIGLLLVAAVAWADLPASAVASSAPDEGDPRIEGALLVDATEVKPGDTFRVGVRFRLDPGWHVYWKN
PGDSGLETEVAWDTPGVTVGPLQWPFPQTFRTPDGFITTHGYDGEAILIADAKAVEGPSTGLLTVSAAVEALVCEVHCIP
AELMLTRSIPLGPQTVRDAETAAVFDTELAKVPRPAKDSGPAATVALDAPQLTAGQDFTGTLTLTAPGGAAVPAVEGDFF
VADRIPGVVRVGLASDGPGRFKLKGKAEPDAQASAPDLTGVLRLGTAATGYQYLEVTAPLAPLVAAGGAAGTPAVVKPPS
VKDSIAAVKPVGAAIATPPAAESSMGLGLALVFAFFGGALLNLMPCVFPVLALKAYGFTRMVQQEQGRVGAHAAAYAAGI
IGTMLLLASVVLAVRAGGASVGWGFQFQEPLFVAGVCAVLVAFALNLFGVFNVGLDGTALAGKVDQSHGLMHSAGEGVLA
VVLATPCSAPLLGTAVGFAFAAGPMTVLAVFTALGLGLALPFCVLVLVPGLAKKLPKPGAWMERFKQVLGFALLATTVWL
VWVMGGLAGVDGMARLLAFLVAVGLVTWLYGQGQAQDGVRKLATVAVAAGVLVASGLLTLRFDDQDPVEAPRVGSTVAQA
QPWSADAVNAALAAGQPVFIDFTADWCLTCKFNERTVLSTDEVRDAFKKHQVAFFIADWTRRDASITTKLAEHGRAGVPM
YLVLSPGAPDKPEVLPELLTPGVVTDAVTRAAACAPSKLGNGANVLCAAGFPSH
>Mature_773_residues
THQQSKRLGVVGGIGLLLVAAVAWADLPASAVASSAPDEGDPRIEGALLVDATEVKPGDTFRVGVRFRLDPGWHVYWKNP
GDSGLETEVAWDTPGVTVGPLQWPFPQTFRTPDGFITTHGYDGEAILIADAKAVEGPSTGLLTVSAAVEALVCEVHCIPA
ELMLTRSIPLGPQTVRDAETAAVFDTELAKVPRPAKDSGPAATVALDAPQLTAGQDFTGTLTLTAPGGAAVPAVEGDFFV
ADRIPGVVRVGLASDGPGRFKLKGKAEPDAQASAPDLTGVLRLGTAATGYQYLEVTAPLAPLVAAGGAAGTPAVVKPPSV
KDSIAAVKPVGAAIATPPAAESSMGLGLALVFAFFGGALLNLMPCVFPVLALKAYGFTRMVQQEQGRVGAHAAAYAAGII
GTMLLLASVVLAVRAGGASVGWGFQFQEPLFVAGVCAVLVAFALNLFGVFNVGLDGTALAGKVDQSHGLMHSAGEGVLAV
VLATPCSAPLLGTAVGFAFAAGPMTVLAVFTALGLGLALPFCVLVLVPGLAKKLPKPGAWMERFKQVLGFALLATTVWLV
WVMGGLAGVDGMARLLAFLVAVGLVTWLYGQGQAQDGVRKLATVAVAAGVLVASGLLTLRFDDQDPVEAPRVGSTVAQAQ
PWSADAVNAALAAGQPVFIDFTADWCLTCKFNERTVLSTDEVRDAFKKHQVAFFIADWTRRDASITTKLAEHGRAGVPMY
LVLSPGAPDKPEVLPELLTPGVVTDAVTRAAACAPSKLGNGANVLCAAGFPSH

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=449, Percent_Identity=26.2806236080178, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 79379; Mature: 79248

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHQQSKRLGVVGGIGLLLVAAVAWADLPASAVASSAPDEGDPRIEGALLVDATEVKPGD
CCCCCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCEEEEEECCCCCCC
TFRVGVRFRLDPGWHVYWKNPGDSGLETEVAWDTPGVTVGPLQWPFPQTFRTPDGFITTH
EEEEEEEEEECCCEEEEECCCCCCCCEEEEEECCCCCEECCCCCCCCCCCCCCCCEEEEC
GYDGEAILIADAKAVEGPSTGLLTVSAAVEALVCEVHCIPAELMLTRSIPLGPQTVRDAE
CCCCCEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHEECCHHHHEECCCCCCCHHHCCCH
TAAVFDTELAKVPRPAKDSGPAATVALDAPQLTAGQDFTGTLTLTAPGGAAVPAVEGDFF
HHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEE
VADRIPGVVRVGLASDGPGRFKLKGKAEPDAQASAPDLTGVLRLGTAATGYQYLEVTAPL
EECCCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCH
APLVAAGGAAGTPAVVKPPSVKDSIAAVKPVGAAIATPPAAESSMGLGLALVFAFFGGAL
HHHHHCCCCCCCCCEECCCCCCHHHHHHCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHH
LNLMPCVFPVLALKAYGFTRMVQQEQGRVGAHAAAYAAGIIGTMLLLASVVLAVRAGGAS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VGWGFQFQEPLFVAGVCAVLVAFALNLFGVFNVGLDGTALAGKVDQSHGLMHSAGEGVLA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHCCCHHCCCCCEEE
VVLATPCSAPLLGTAVGFAFAAGPMTVLAVFTALGLGLALPFCVLVLVPGLAKKLPKPGA
EEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
WMERFKQVLGFALLATTVWLVWVMGGLAGVDGMARLLAFLVAVGLVTWLYGQGQAQDGVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KLATVAVAAGVLVASGLLTLRFDDQDPVEAPRVGSTVAQAQPWSADAVNAALAAGQPVFI
HHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHCCCEEEE
DFTADWCLTCKFNERTVLSTDEVRDAFKKHQVAFFIADWTRRDASITTKLAEHGRAGVPM
EEECCEEEEEEECCCEEECHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHCCCCCCCE
YLVLSPGAPDKPEVLPELLTPGVVTDAVTRAAACAPSKLGNGANVLCAAGFPSH
EEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCHHHCCCCCCEEEECCCCCC
>Mature Secondary Structure 
THQQSKRLGVVGGIGLLLVAAVAWADLPASAVASSAPDEGDPRIEGALLVDATEVKPGD
CCCCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCEEEEEECCCCCCC
TFRVGVRFRLDPGWHVYWKNPGDSGLETEVAWDTPGVTVGPLQWPFPQTFRTPDGFITTH
EEEEEEEEEECCCEEEEECCCCCCCCEEEEEECCCCCEECCCCCCCCCCCCCCCCEEEEC
GYDGEAILIADAKAVEGPSTGLLTVSAAVEALVCEVHCIPAELMLTRSIPLGPQTVRDAE
CCCCCEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHEECCHHHHEECCCCCCCHHHCCCH
TAAVFDTELAKVPRPAKDSGPAATVALDAPQLTAGQDFTGTLTLTAPGGAAVPAVEGDFF
HHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEE
VADRIPGVVRVGLASDGPGRFKLKGKAEPDAQASAPDLTGVLRLGTAATGYQYLEVTAPL
EECCCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCH
APLVAAGGAAGTPAVVKPPSVKDSIAAVKPVGAAIATPPAAESSMGLGLALVFAFFGGAL
HHHHHCCCCCCCCCEECCCCCCHHHHHHCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHH
LNLMPCVFPVLALKAYGFTRMVQQEQGRVGAHAAAYAAGIIGTMLLLASVVLAVRAGGAS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VGWGFQFQEPLFVAGVCAVLVAFALNLFGVFNVGLDGTALAGKVDQSHGLMHSAGEGVLA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHCCCHHCCCCCEEE
VVLATPCSAPLLGTAVGFAFAAGPMTVLAVFTALGLGLALPFCVLVLVPGLAKKLPKPGA
EEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
WMERFKQVLGFALLATTVWLVWVMGGLAGVDGMARLLAFLVAVGLVTWLYGQGQAQDGVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KLATVAVAAGVLVASGLLTLRFDDQDPVEAPRVGSTVAQAQPWSADAVNAALAAGQPVFI
HHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHCCCEEEE
DFTADWCLTCKFNERTVLSTDEVRDAFKKHQVAFFIADWTRRDASITTKLAEHGRAGVPM
EEECCEEEEEEECCCEEECHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHCCCCCCCE
YLVLSPGAPDKPEVLPELLTPGVVTDAVTRAAACAPSKLGNGANVLCAAGFPSH
EEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCHHHCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA