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The map label for this gene is cysJ [H]

Identifier: 108761948

GI number: 108761948

Start: 2714128

End: 2715954

Strand: Reverse

Name: cysJ [H]

Synonym: MXAN_2335

Alternate gene names: 108761948

Gene position: 2715954-2714128 (Counterclockwise)

Preceding gene: 108760381

Following gene: 108763120

Centisome position: 29.72

GC content: 69.51

Gene sequence:

>1827_bases
ATGAGCGCATCCCCTGCCACCCATGCTCCCCCGTTCATCAACGCTCTGCTGGGTGAGAACAAGAGTGCCCTGCTGCTCAA
GCTCGTGGAGGAGATGGACGCCTCCGCCCTGCACTGGCTGAGCGGCTACACGGCGGGACTGGCCGTCCGCGCCCCCCAGA
CCACCGTTGTCCCCGTGACGCCCGTACCCGTGGCCGCCCCCGCCGGTCACTTCACCATCATCTACGGGACGCAGACGGGT
AACAGCCGCCTCCTGGCCGAGCGCCTCAAGCACCAGGTGGAGTCCGCCGGGCTCGCCACGCGGCTGTTCCGGGCCAGCGA
CTATCCGGTGCGGGAGCTGGCCAAGGAGAAGCTGCTCTGCGTGGTCATCAGCACCCAGGGAGATGGCGACCCGCCGGACG
ACGCACGCGGTTTCAGTGAGTTCATCCTCGGCAAGCGCGCGCCTCGCATGGAGGGGCTGCGCTACGCCGTGCTGGGGCTG
GGAGACTCCAGCTACCCGCGCTTCTGCGAGGTGGGCCGGCGGCTCGACGCCCGCTTCGCGGAGTTGGGCGCCAGCCGGCT
GTTGGAGCGTGCCGATTGCGATGTGGACTTCGAGCCCGTGGCCAAGGGTTGGCTCGACCAGGCCTACACCCTGGCGCGCG
AAGCACTGACTCCGCAGGCGACGGTGACGGCCACGGTCGTGCCGCTGCGGGAGCCGCACGCCACGCCCGCGTTCACCAAG
GAAGCGCCCTACACGGCGGAGGTGCTGCTCAATCAGCGCATCACTGCACGCGGCGCGCTCAAGGACGTGCGGCACCTGGA
GCTGTCGCTCGCGGGCTCCGGGCTGGAATACGCCCCCGGCGACGCGCTGGGCGTGTGGCCCCACAATCCGCCGGAGCTGG
TGGCGTCCTTCCTGTCCGAGCTGCGCCTCGACGGAGAAGCGGCGGTCACCCGAGAGGGCCGCACGCTCCCGCTGGCGCGC
TGGCTGAGTGACGAGTTGGAAATCACCAGGCTCAACCGCCCCTTCCTGGAGCGACAAGCCACGCTGTCCGGCAGCGCGGC
GCTGCACGAAGTGCTCGAACCGGGCCGCACCGAGGCCTTCCGCGCACTGCTGGCGGGGCATCAGGTCATCGACGTACTCC
GCGCCCACAAGGCCACCTGGGACGCCACGGAGCTGGTCCAGTCCCTGCGCCGGCTGACGCCCCGGTTGTACTCGATTGCC
TCCAGCCCCAAGCGCGTGGGTGAAGAGGCGCACCTCACGGTGGCGGTGGTGGACTACACGGTGTTCGACCTGCGGCACTT
CGGCGCGGCGTCGTACCACCTGGCCACGCGCACGGCCGGCACCGACACGGTCCGCATCTTCATCGAGCCGAACGAACGCT
TCCGGCTGCCGCAGGACGGCGACAAGGACGTGCTGATGATTGGCCCTGGCACCGGCGTGGCGCCCTTCCGGGCCTTCGTC
CAGGAGCGCGCGGAGACCGGAGCGAAGGGCCGCAACTGGCTCTTCTTCGGTGAGCAACACTTCCGCACCCAGTTCCTCTA
CCAGACGGAGTGGCAGGAGGCCCTGAAGAAGCAGACGCTGCACCGGCTGTCACTCGCCTTCTCGCGGGACCGCGCTCAGA
AGGTCTACGTGCAGCACCGGCTGCGTGAGTCCGGACGTGACGTCTACGAATGGCTCGAAGGAGGCGCCCACCTCTACGTG
TGCGGCGACGCCCAGCGCATGGCCCCGGATGTCCACGAGGCACTGGTGGACGTCGTCTCCACCCACGGCGGCAAGAGCCG
CGAGGACGCGCACGCCTGGCTCGAATCCCTGCGCGAGCAGCGGCGCTACCTGCGCGACGTCTACTGA

Upstream 100 bases:

>100_bases
CGGAGGCCCGCGATGCCGGCGCCGCGTGGCTGGAGCTGGAAGCCACTGAAGACCTGCAGCAACACCTCGACCGGATCATC
TCCCTCCGGGAGGCCGCACG

Downstream 100 bases:

>100_bases
CCCATTCCGATTGCGAGCAACGACATGAGCCACCAGCCCAAGCCTCTCTCCGAAGTGGAGCACATCAAGACCCAGAGCCG
CCTGCTCCGGGGAAGTCTGG

Product: sulfite reductase [NADPH] flavoprotein, alpha-component

Products: NA

Alternate protein names: SiR-FP [H]

Number of amino acids: Translated: 608; Mature: 607

Protein sequence:

>608_residues
MSASPATHAPPFINALLGENKSALLLKLVEEMDASALHWLSGYTAGLAVRAPQTTVVPVTPVPVAAPAGHFTIIYGTQTG
NSRLLAERLKHQVESAGLATRLFRASDYPVRELAKEKLLCVVISTQGDGDPPDDARGFSEFILGKRAPRMEGLRYAVLGL
GDSSYPRFCEVGRRLDARFAELGASRLLERADCDVDFEPVAKGWLDQAYTLAREALTPQATVTATVVPLREPHATPAFTK
EAPYTAEVLLNQRITARGALKDVRHLELSLAGSGLEYAPGDALGVWPHNPPELVASFLSELRLDGEAAVTREGRTLPLAR
WLSDELEITRLNRPFLERQATLSGSAALHEVLEPGRTEAFRALLAGHQVIDVLRAHKATWDATELVQSLRRLTPRLYSIA
SSPKRVGEEAHLTVAVVDYTVFDLRHFGAASYHLATRTAGTDTVRIFIEPNERFRLPQDGDKDVLMIGPGTGVAPFRAFV
QERAETGAKGRNWLFFGEQHFRTQFLYQTEWQEALKKQTLHRLSLAFSRDRAQKVYVQHRLRESGRDVYEWLEGGAHLYV
CGDAQRMAPDVHEALVDVVSTHGGKSREDAHAWLESLREQRRYLRDVY

Sequences:

>Translated_608_residues
MSASPATHAPPFINALLGENKSALLLKLVEEMDASALHWLSGYTAGLAVRAPQTTVVPVTPVPVAAPAGHFTIIYGTQTG
NSRLLAERLKHQVESAGLATRLFRASDYPVRELAKEKLLCVVISTQGDGDPPDDARGFSEFILGKRAPRMEGLRYAVLGL
GDSSYPRFCEVGRRLDARFAELGASRLLERADCDVDFEPVAKGWLDQAYTLAREALTPQATVTATVVPLREPHATPAFTK
EAPYTAEVLLNQRITARGALKDVRHLELSLAGSGLEYAPGDALGVWPHNPPELVASFLSELRLDGEAAVTREGRTLPLAR
WLSDELEITRLNRPFLERQATLSGSAALHEVLEPGRTEAFRALLAGHQVIDVLRAHKATWDATELVQSLRRLTPRLYSIA
SSPKRVGEEAHLTVAVVDYTVFDLRHFGAASYHLATRTAGTDTVRIFIEPNERFRLPQDGDKDVLMIGPGTGVAPFRAFV
QERAETGAKGRNWLFFGEQHFRTQFLYQTEWQEALKKQTLHRLSLAFSRDRAQKVYVQHRLRESGRDVYEWLEGGAHLYV
CGDAQRMAPDVHEALVDVVSTHGGKSREDAHAWLESLREQRRYLRDVY
>Mature_607_residues
SASPATHAPPFINALLGENKSALLLKLVEEMDASALHWLSGYTAGLAVRAPQTTVVPVTPVPVAAPAGHFTIIYGTQTGN
SRLLAERLKHQVESAGLATRLFRASDYPVRELAKEKLLCVVISTQGDGDPPDDARGFSEFILGKRAPRMEGLRYAVLGLG
DSSYPRFCEVGRRLDARFAELGASRLLERADCDVDFEPVAKGWLDQAYTLAREALTPQATVTATVVPLREPHATPAFTKE
APYTAEVLLNQRITARGALKDVRHLELSLAGSGLEYAPGDALGVWPHNPPELVASFLSELRLDGEAAVTREGRTLPLARW
LSDELEITRLNRPFLERQATLSGSAALHEVLEPGRTEAFRALLAGHQVIDVLRAHKATWDATELVQSLRRLTPRLYSIAS
SPKRVGEEAHLTVAVVDYTVFDLRHFGAASYHLATRTAGTDTVRIFIEPNERFRLPQDGDKDVLMIGPGTGVAPFRAFVQ
ERAETGAKGRNWLFFGEQHFRTQFLYQTEWQEALKKQTLHRLSLAFSRDRAQKVYVQHRLRESGRDVYEWLEGGAHLYVC
GDAQRMAPDVHEALVDVVSTHGGKSREDAHAWLESLREQRRYLRDVY

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow f

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI7657393, Length=603, Percent_Identity=33.4991708126036, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI221316709, Length=603, Percent_Identity=33.4991708126036, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI221316705, Length=612, Percent_Identity=33.0065359477124, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI127139033, Length=613, Percent_Identity=29.3637846655791, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI221316707, Length=531, Percent_Identity=33.5216572504708, Blast_Score=207, Evalue=3e-53,
Organism=Homo sapiens, GI24041029, Length=597, Percent_Identity=30.4857621440536, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI10835173, Length=651, Percent_Identity=28.2642089093702, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI40254422, Length=650, Percent_Identity=29.5384615384615, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI169790956, Length=438, Percent_Identity=29.2237442922374, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI169790958, Length=438, Percent_Identity=29.2237442922374, Blast_Score=135, Evalue=1e-31,
Organism=Escherichia coli, GI1789123, Length=606, Percent_Identity=43.8943894389439, Blast_Score=479, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI17554134, Length=610, Percent_Identity=28.6885245901639, Blast_Score=228, Evalue=6e-60,
Organism=Caenorhabditis elegans, GI17566446, Length=579, Percent_Identity=27.1157167530225, Blast_Score=138, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17531441, Length=148, Percent_Identity=35.8108108108108, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI32563863, Length=127, Percent_Identity=37.007874015748, Blast_Score=85, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6321832, Length=639, Percent_Identity=28.3255086071987, Blast_Score=187, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6325305, Length=634, Percent_Identity=23.9747634069401, Blast_Score=136, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6321143, Length=390, Percent_Identity=27.9487179487179, Blast_Score=130, Evalue=6e-31,
Organism=Drosophila melanogaster, GI17137192, Length=602, Percent_Identity=29.9003322259136, Blast_Score=226, Evalue=5e-59,
Organism=Drosophila melanogaster, GI24582192, Length=515, Percent_Identity=29.7087378640777, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24660907, Length=596, Percent_Identity=27.3489932885906, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24660903, Length=596, Percent_Identity=27.3489932885906, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI78706872, Length=522, Percent_Identity=30.0766283524904, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24583543, Length=522, Percent_Identity=30.0766283524904, Blast_Score=173, Evalue=4e-43,
Organism=Drosophila melanogaster, GI78706876, Length=522, Percent_Identity=30.0766283524904, Blast_Score=173, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24647438, Length=424, Percent_Identity=27.8301886792453, Blast_Score=97, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010199
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1 [H]

EC number: =1.8.1.2 [H]

Molecular weight: Translated: 67496; Mature: 67365

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASPATHAPPFINALLGENKSALLLKLVEEMDASALHWLSGYTAGLAVRAPQTTVVPVT
CCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHCCCCCEEEECCCCEEEECC
PVPVAAPAGHFTIIYGTQTGNSRLLAERLKHQVESAGLATRLFRASDYPVRELAKEKLLC
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCEEE
VVISTQGDGDPPDDARGFSEFILGKRAPRMEGLRYAVLGLGDSSYPRFCEVGRRLDARFA
EEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
ELGASRLLERADCDVDFEPVAKGWLDQAYTLAREALTPQATVTATVVPLREPHATPAFTK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCC
EAPYTAEVLLNQRITARGALKDVRHLELSLAGSGLEYAPGDALGVWPHNPPELVASFLSE
CCCCHHHHHHHCCHHHHHHHHHHHHHEEEECCCCCCCCCCCEEECCCCCCHHHHHHHHHH
LRLDGEAAVTREGRTLPLARWLSDELEITRLNRPFLERQATLSGSAALHEVLEPGRTEAF
HCCCCCCEEECCCCCCHHHHHHCCCCEEEECCCHHHHHHHHCCCHHHHHHHHCCCHHHHH
RALLAGHQVIDVLRAHKATWDATELVQSLRRLTPRLYSIASSPKRVGEEAHLTVAVVDYT
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEEEHHH
VFDLRHFGAASYHLATRTAGTDTVRIFIEPNERFRLPQDGDKDVLMIGPGTGVAPFRAFV
HHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCCHHHHHHHH
QERAETGAKGRNWLFFGEQHFRTQFLYQTEWQEALKKQTLHRLSLAFSRDRAQKVYVQHR
HHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRESGRDVYEWLEGGAHLYVCGDAQRMAPDVHEALVDVVSTHGGKSREDAHAWLESLREQ
HHHCCHHHHHHHHCCCEEEEECCHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
RRYLRDVY
HHHHHHCC
>Mature Secondary Structure 
SASPATHAPPFINALLGENKSALLLKLVEEMDASALHWLSGYTAGLAVRAPQTTVVPVT
CCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHCCCCCEEEECCCCEEEECC
PVPVAAPAGHFTIIYGTQTGNSRLLAERLKHQVESAGLATRLFRASDYPVRELAKEKLLC
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCEEE
VVISTQGDGDPPDDARGFSEFILGKRAPRMEGLRYAVLGLGDSSYPRFCEVGRRLDARFA
EEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
ELGASRLLERADCDVDFEPVAKGWLDQAYTLAREALTPQATVTATVVPLREPHATPAFTK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCC
EAPYTAEVLLNQRITARGALKDVRHLELSLAGSGLEYAPGDALGVWPHNPPELVASFLSE
CCCCHHHHHHHCCHHHHHHHHHHHHHEEEECCCCCCCCCCCEEECCCCCCHHHHHHHHHH
LRLDGEAAVTREGRTLPLARWLSDELEITRLNRPFLERQATLSGSAALHEVLEPGRTEAF
HCCCCCCEEECCCCCCHHHHHHCCCCEEEECCCHHHHHHHHCCCHHHHHHHHCCCHHHHH
RALLAGHQVIDVLRAHKATWDATELVQSLRRLTPRLYSIASSPKRVGEEAHLTVAVVDYT
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEEEHHH
VFDLRHFGAASYHLATRTAGTDTVRIFIEPNERFRLPQDGDKDVLMIGPGTGVAPFRAFV
HHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCCHHHHHHHH
QERAETGAKGRNWLFFGEQHFRTQFLYQTEWQEALKKQTLHRLSLAFSRDRAQKVYVQHR
HHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRESGRDVYEWLEGGAHLYVCGDAQRMAPDVHEALVDVVSTHGGKSREDAHAWLESLREQ
HHHCCHHHHHHHHCCCEEEEECCHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
RRYLRDVY
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA