Click here to switch to the map view.

The map label for this gene is steT [H]

Identifier: 108761529

GI number: 108761529

Start: 1830603

End: 1832000

Strand: Direct

Name: steT [H]

Synonym: MXAN_1558

Alternate gene names: 108761529

Gene position: 1830603-1832000 (Clockwise)

Preceding gene: 108758816

Following gene: 108762522

Centisome position: 20.03

GC content: 70.17

Gene sequence:

>1398_bases
GTGAAGCGTGGTGAGTCCGCGCCGTCGCCGTCGTTGCGCGTGCTGGATGTGATGGCCCTGACAGTGGGCATCGTCCTGGG
AGCAGGCATCTTCAAGGCGCCCTCGCTGGTGGCCGCGCAGTCCGGCAGCGGTGAGGCCATGCTGCTCACGTGGCTGCTGG
GCGGTGTCGCGTCGCTGGTGGGCGCGCTGTGTTACGCGGAGCTGGCCAGCGCCTGGCCACACCCGGGCGGGGACTACCAC
TACCTGTACCGCGCGCTGGGCAAGGGGCCCGCTTTCCTTTTCGCGTGGGCGCGGCTGACCGTCATCCCCACCGGCTCCAT
CGCACTGCTGGCCTTCGTCTTCGGGGACTACGCCACGCAGCTCTTCCCCCTGGGCCTGTATTCGTCGCCCGTCTATGCGG
CCATGCTGGTGGTGGGGCTGACGGCGGTGAACATCGCCGGACTTCGGCAGGGGACCCGTACGCAGAACCTGCTCACGGCC
CTGGAGGTTCTGGGCGTGGGGGCTGTCGTCATCGTGGGGTTGCTTTTCACGCCCGCGCTGGTGCCCGCGGCGGCGCCGCC
GGCACCGGCCGCGTCGTCAGGGACCGCCTGGGGCCTGGCCATGGTGTTCGTGCTGCTGACGTACGGCGGCTGGAATGAGG
TGGCGTACCTGTCCTCGGAGGTGCGGGGTTCGCGGCGCACCATCGCCTGGTCGCTGTTGGCGAGCATCGGGCTGGTGACG
GCGCTGTACCTGCTGGTCAACGTGGCCTACCTGCGCGGCCTGGGGCTCGAAGGCATGGCGCGTTCGGAGGCGGTGGCCGC
GGACCTGATGCAGCGCGCGGTGGGCAGCGGGGGCGCGCTGGTGTTGAGCGTCATCATCGCCATCTCCGCGCTGACGTCCG
CCAACGCCACGGTGCTGACGGGGGCTCGGACCCACTATGCCTTCGGGCGGGACAGCGTGCTGTTCAATGGGCTGGGGCAG
TGGCATGCGAAGTCCAATGGCCCGTCCCGCGCGCTGCTGGTGCAGGGGGCCATCTCCCTGGCGCTGGTGGGGCTGGGGAC
GCTGACGCGTCAGGGCTTCGAGACGATGGTGGAGTACACCGCGCCCGTCTTCTGGCTCTTCTTCCTGCTGACGGGCGTGT
CGCTGATGGTGCTGCGCGTGCGTGAGCCGGATGCGCCGCGGCCGTTCCGCGTGCCGCTGTATCCGCTCACGCCGCTGCTC
TTCATCGGCATCTGCGCCTACGTCCTCTATTCCAGCCTGGCCTTCACCGGGCTGGGCGCGCTCGCGGGGCTGGCAGTGCT
GGGCACGGGCGGCGTGCTGCTCGCCGTGGAGGCGGTGCGCACCCGCAGGGGCTCGCAGGGGACCTCCCCCAAGGCCAGTT
CCTCTCCCAGACTGCAACGAACGAAGGAGGCGACATGA

Upstream 100 bases:

>100_bases
CCACGGCCGGGTCGCGGCCTCATCTTGCGCCGGACGGCGGAGGCTGCCGCGGCGCGTGGAGCACGTCACCATGCAGGAGC
AGCAAGCAGGAGTCGAAGTC

Downstream 100 bases:

>100_bases
AGCGAATGATGGTGGTTTTCGCGTTCACGGCGGCGATGGCCGCGAACGCCGCGAGCGTTTCGACGGCGCAGCAGACGGTG
ACGGTGCAGGTCCGCGGACC

Product: amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MKRGESAPSPSLRVLDVMALTVGIVLGAGIFKAPSLVAAQSGSGEAMLLTWLLGGVASLVGALCYAELASAWPHPGGDYH
YLYRALGKGPAFLFAWARLTVIPTGSIALLAFVFGDYATQLFPLGLYSSPVYAAMLVVGLTAVNIAGLRQGTRTQNLLTA
LEVLGVGAVVIVGLLFTPALVPAAAPPAPAASSGTAWGLAMVFVLLTYGGWNEVAYLSSEVRGSRRTIAWSLLASIGLVT
ALYLLVNVAYLRGLGLEGMARSEAVAADLMQRAVGSGGALVLSVIIAISALTSANATVLTGARTHYAFGRDSVLFNGLGQ
WHAKSNGPSRALLVQGAISLALVGLGTLTRQGFETMVEYTAPVFWLFFLLTGVSLMVLRVREPDAPRPFRVPLYPLTPLL
FIGICAYVLYSSLAFTGLGALAGLAVLGTGGVLLAVEAVRTRRGSQGTSPKASSSPRLQRTKEAT

Sequences:

>Translated_465_residues
MKRGESAPSPSLRVLDVMALTVGIVLGAGIFKAPSLVAAQSGSGEAMLLTWLLGGVASLVGALCYAELASAWPHPGGDYH
YLYRALGKGPAFLFAWARLTVIPTGSIALLAFVFGDYATQLFPLGLYSSPVYAAMLVVGLTAVNIAGLRQGTRTQNLLTA
LEVLGVGAVVIVGLLFTPALVPAAAPPAPAASSGTAWGLAMVFVLLTYGGWNEVAYLSSEVRGSRRTIAWSLLASIGLVT
ALYLLVNVAYLRGLGLEGMARSEAVAADLMQRAVGSGGALVLSVIIAISALTSANATVLTGARTHYAFGRDSVLFNGLGQ
WHAKSNGPSRALLVQGAISLALVGLGTLTRQGFETMVEYTAPVFWLFFLLTGVSLMVLRVREPDAPRPFRVPLYPLTPLL
FIGICAYVLYSSLAFTGLGALAGLAVLGTGGVLLAVEAVRTRRGSQGTSPKASSSPRLQRTKEAT
>Mature_465_residues
MKRGESAPSPSLRVLDVMALTVGIVLGAGIFKAPSLVAAQSGSGEAMLLTWLLGGVASLVGALCYAELASAWPHPGGDYH
YLYRALGKGPAFLFAWARLTVIPTGSIALLAFVFGDYATQLFPLGLYSSPVYAAMLVVGLTAVNIAGLRQGTRTQNLLTA
LEVLGVGAVVIVGLLFTPALVPAAAPPAPAASSGTAWGLAMVFVLLTYGGWNEVAYLSSEVRGSRRTIAWSLLASIGLVT
ALYLLVNVAYLRGLGLEGMARSEAVAADLMQRAVGSGGALVLSVIIAISALTSANATVLTGARTHYAFGRDSVLFNGLGQ
WHAKSNGPSRALLVQGAISLALVGLGTLTRQGFETMVEYTAPVFWLFFLLTGVSLMVLRVREPDAPRPFRVPLYPLTPLL
FIGICAYVLYSSLAFTGLGALAGLAVLGTGGVLLAVEAVRTRRGSQGTSPKASSSPRLQRTKEAT

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI186910308, Length=429, Percent_Identity=28.4382284382284, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI186910306, Length=429, Percent_Identity=28.4382284382284, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI186910304, Length=429, Percent_Identity=28.4382284382284, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI115648063, Length=433, Percent_Identity=29.5612009237875, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI115648022, Length=433, Percent_Identity=29.5612009237875, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI187423910, Length=385, Percent_Identity=29.6103896103896, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI7657591, Length=385, Percent_Identity=29.6103896103896, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI33286428, Length=420, Percent_Identity=30.2380952380952, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI71979932, Length=433, Percent_Identity=29.3302540415704, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI7657683, Length=401, Percent_Identity=29.426433915212, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI9790235, Length=407, Percent_Identity=28.2555282555283, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI33286430, Length=223, Percent_Identity=29.1479820627803, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI71999149, Length=388, Percent_Identity=26.2886597938144, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI258614003, Length=376, Percent_Identity=26.5957446808511, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI258614005, Length=376, Percent_Identity=26.5957446808511, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4507047, Length=430, Percent_Identity=23.0232558139535, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI87082250, Length=432, Percent_Identity=25.2314814814815, Blast_Score=105, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17540018, Length=458, Percent_Identity=27.5109170305677, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI32566699, Length=332, Percent_Identity=28.3132530120482, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71993915, Length=390, Percent_Identity=28.2051282051282, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71995388, Length=393, Percent_Identity=28.498727735369, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI71995382, Length=393, Percent_Identity=27.9898218829517, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17568033, Length=410, Percent_Identity=27.8048780487805, Blast_Score=131, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI71982612, Length=398, Percent_Identity=26.8844221105528, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71982608, Length=398, Percent_Identity=26.8844221105528, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI193208714, Length=417, Percent_Identity=24.9400479616307, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI32566695, Length=417, Percent_Identity=24.9400479616307, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71990446, Length=423, Percent_Identity=23.1678486997636, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71982623, Length=274, Percent_Identity=27.007299270073, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17532491, Length=467, Percent_Identity=25.0535331905782, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71987339, Length=391, Percent_Identity=22.7621483375959, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6321751, Length=392, Percent_Identity=22.4489795918367, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321492, Length=337, Percent_Identity=23.1454005934718, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21357367, Length=424, Percent_Identity=29.0094339622642, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24641995, Length=384, Percent_Identity=30.2083333333333, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24641993, Length=384, Percent_Identity=30.2083333333333, Blast_Score=155, Evalue=7e-38,
Organism=Drosophila melanogaster, GI221331183, Length=412, Percent_Identity=28.8834951456311, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI17647653, Length=412, Percent_Identity=28.8834951456311, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24664379, Length=412, Percent_Identity=28.8834951456311, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI45550968, Length=402, Percent_Identity=27.6119402985075, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI19921172, Length=402, Percent_Identity=27.6119402985075, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI24651635, Length=431, Percent_Identity=26.4501160092807, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24651633, Length=431, Percent_Identity=26.4501160092807, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI221512776, Length=381, Percent_Identity=25.1968503937008, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24666159, Length=381, Percent_Identity=25.1968503937008, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24667468, Length=423, Percent_Identity=26.0047281323877, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24668806, Length=431, Percent_Identity=23.8979118329466, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356285, Length=431, Percent_Identity=23.8979118329466, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24668802, Length=431, Percent_Identity=23.8979118329466, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 48338; Mature: 48338

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRGESAPSPSLRVLDVMALTVGIVLGAGIFKAPSLVAAQSGSGEAMLLTWLLGGVASLV
CCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHH
GALCYAELASAWPHPGGDYHYLYRALGKGPAFLFAWARLTVIPTGSIALLAFVFGDYATQ
HHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHEEEHHHHEEECCCHHHHHHHHHHHHHHH
LFPLGLYSSPVYAAMLVVGLTAVNIAGLRQGTRTQNLLTALEVLGVGAVVIVGLLFTPAL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPAAAPPAPAASSGTAWGLAMVFVLLTYGGWNEVAYLSSEVRGSRRTIAWSLLASIGLVT
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ALYLLVNVAYLRGLGLEGMARSEAVAADLMQRAVGSGGALVLSVIIAISALTSANATVLT
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEE
GARTHYAFGRDSVLFNGLGQWHAKSNGPSRALLVQGAISLALVGLGTLTRQGFETMVEYT
CCCHHCCCCCCCHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APVFWLFFLLTGVSLMVLRVREPDAPRPFRVPLYPLTPLLFIGICAYVLYSSLAFTGLGA
HHHHHHHHHHHHHHHEEEEECCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAGLAVLGTGGVLLAVEAVRTRRGSQGTSPKASSSPRLQRTKEAT
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCC
>Mature Secondary Structure
MKRGESAPSPSLRVLDVMALTVGIVLGAGIFKAPSLVAAQSGSGEAMLLTWLLGGVASLV
CCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHH
GALCYAELASAWPHPGGDYHYLYRALGKGPAFLFAWARLTVIPTGSIALLAFVFGDYATQ
HHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHEEEHHHHEEECCCHHHHHHHHHHHHHHH
LFPLGLYSSPVYAAMLVVGLTAVNIAGLRQGTRTQNLLTALEVLGVGAVVIVGLLFTPAL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPAAAPPAPAASSGTAWGLAMVFVLLTYGGWNEVAYLSSEVRGSRRTIAWSLLASIGLVT
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ALYLLVNVAYLRGLGLEGMARSEAVAADLMQRAVGSGGALVLSVIIAISALTSANATVLT
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEE
GARTHYAFGRDSVLFNGLGQWHAKSNGPSRALLVQGAISLALVGLGTLTRQGFETMVEYT
CCCHHCCCCCCCHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APVFWLFFLLTGVSLMVLRVREPDAPRPFRVPLYPLTPLLFIGICAYVLYSSLAFTGLGA
HHHHHHHHHHHHHHHEEEEECCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAGLAVLGTGGVLLAVEAVRTRRGSQGTSPKASSSPRLQRTKEAT
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]