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The map label for this gene is hscB [H]

Identifier: 108761503

GI number: 108761503

Start: 6254514

End: 6255101

Strand: Direct

Name: hscB [H]

Synonym: MXAN_5004

Alternate gene names: 108761503

Gene position: 6254514-6255101 (Clockwise)

Preceding gene: 108760194

Following gene: 108760540

Centisome position: 68.43

GC content: 69.05

Gene sequence:

>588_bases
TTGTCCCCTCCCCGCATTGGAGAGCCCCCTTTGAGGACCCACTTCGACGTCTTCGGCCTGAAGCGCGCCTATGACGTGGA
CGTGCCGGCGCTGGAGAAGCAGTACCGCGAGCTGTCGTTGCAGCTCCACCCGGACCGCGTGGCACAGGCCAGCGCGCGCG
AGCGCCTGCAGGCCCTGGAGGGCACCACCGCCCTCAACGAGGCCTTCAAGACGTTGAAGGACCCGGTGCGCCGCGCCTTC
TACCTGCTCAAGCTGCACGGCATCGACCTGGACCGCGAGGACGCGGGCGCGCAGAAGGACATGCCCCTTGCCTTCCTGGA
GGAGGTCATGGACCTGCGCGAGTCGCTGGACACCGCCATGGCGAAGAAGGACCTGGGCCGCGCCCGGGCCATGGCGGACG
ACGTGGAGGCCCGGAAGAAGGCGGCCCTCACCGAGGCGGCGGAGTCGCTTCGCACCCTGGAGGCAGGCGAGCCGGGGGAC
GGCGGGCAGGAACAAGTGAGAAAGGCATCGCACGCGCTGGGGCGGGTGCGCTACTTCACGCGCTTCCTCGAGCAGGTGGA
CGCGTTCGAGGAGGAGATTCAGGCGTGA

Upstream 100 bases:

>100_bases
CGGAGAGAGCTTCTCCGTCTGACGCGGCAGCACGCGCTCCGCCCCCTTCTGGGCGGAGCCGCCGCCACGCGGGCCCGGCC
AGCCGCCGGGCCCTTTTCGT

Downstream 100 bases:

>100_bases
GCAAGAACGGCTACCTTCAGATTCACGACCCGCTGAAGCCCAAGGGGCAGGCGGTGGGCATCGACCTGGGCACGACGAAC
TCGCTGGTGGCGGCGGTGGT

Product: Fe-S protein assembly co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MSPPRIGEPPLRTHFDVFGLKRAYDVDVPALEKQYRELSLQLHPDRVAQASARERLQALEGTTALNEAFKTLKDPVRRAF
YLLKLHGIDLDREDAGAQKDMPLAFLEEVMDLRESLDTAMAKKDLGRARAMADDVEARKKAALTEAAESLRTLEAGEPGD
GGQEQVRKASHALGRVRYFTRFLEQVDAFEEEIQA

Sequences:

>Translated_195_residues
MSPPRIGEPPLRTHFDVFGLKRAYDVDVPALEKQYRELSLQLHPDRVAQASARERLQALEGTTALNEAFKTLKDPVRRAF
YLLKLHGIDLDREDAGAQKDMPLAFLEEVMDLRESLDTAMAKKDLGRARAMADDVEARKKAALTEAAESLRTLEAGEPGD
GGQEQVRKASHALGRVRYFTRFLEQVDAFEEEIQA
>Mature_194_residues
SPPRIGEPPLRTHFDVFGLKRAYDVDVPALEKQYRELSLQLHPDRVAQASARERLQALEGTTALNEAFKTLKDPVRRAFY
LLKLHGIDLDREDAGAQKDMPLAFLEEVMDLRESLDTAMAKKDLGRARAMADDVEARKKAALTEAAESLRTLEAGEPGDG
GQEQVRKASHALGRVRYFTRFLEQVDAFEEEIQA

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=178, Percent_Identity=30.8988764044944, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1788876, Length=155, Percent_Identity=36.1290322580645, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 21920; Mature: 21789

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPPRIGEPPLRTHFDVFGLKRAYDVDVPALEKQYRELSLQLHPDRVAQASARERLQALE
CCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
GTTALNEAFKTLKDPVRRAFYLLKLHGIDLDREDAGAQKDMPLAFLEEVMDLRESLDTAM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHH
AKKDLGRARAMADDVEARKKAALTEAAESLRTLEAGEPGDGGQEQVRKASHALGRVRYFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
RFLEQVDAFEEEIQA
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPPRIGEPPLRTHFDVFGLKRAYDVDVPALEKQYRELSLQLHPDRVAQASARERLQALE
CCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
GTTALNEAFKTLKDPVRRAFYLLKLHGIDLDREDAGAQKDMPLAFLEEVMDLRESLDTAM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHH
AKKDLGRARAMADDVEARKKAALTEAAESLRTLEAGEPGDGGQEQVRKASHALGRVRYFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
RFLEQVDAFEEEIQA
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA