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The map label for this gene is sasA [H]

Identifier: 108761393

GI number: 108761393

Start: 7071138

End: 7072604

Strand: Direct

Name: sasA [H]

Synonym: MXAN_5704

Alternate gene names: 108761393

Gene position: 7071138-7072604 (Clockwise)

Preceding gene: 108757350

Following gene: 108762007

Centisome position: 77.37

GC content: 72.12

Gene sequence:

>1467_bases
ATGGAGCCCGCCCGCGCTACGCCCGCCCGTCCGTCCGCTTCCGCACGACAGGCGGCAGGGCTTGCAAGCCACGAAGGAAG
CAGGGAAAACCCACGCCTCGTGACGTCTCCGCCTCCCGTGTCCGGCCCGCTCGAAGAGACGATGTCCCGGGCCATGGACG
CCCAGCGGAGGAGCGTCGTCGGCGCGGGCGCGGCGGTGCGGCTCGTCGGCGCGGCCCTGTTCCTGGCCATCAGCACCACG
CTGTGGCTGGCCGGAGGCCGGGACTGGGGTGTGTACCCACCGGCGTTGGGGCTCTACGCGTCGGTCGCCGGCGTGCTGTT
CATGCTCCGCCAACGGCGCGTGGCCCGGGGCCTGGGCGCGGTGCAGTCCCTGGTGGACGTGGGGCTCGTGTACTGGATTC
AGTCCACGACCCTGCTTGTCTCGCCCTTTCCCGCAGGTGTGGCGGGCTTCAGCCTGGGCCTGTTCGCGCTCGTCGTCGCC
CTGAGCGGGCTGGGCATGCGAGGCACCGTCGTCTACGGGACCGCGCTGTTGTCCGCCGTGGCCCAGGCGGCACTCATGCG
GCAGGCGAGCGTGGGTTGGGGCGCGGTGGCCATCGCCGTGGTGGCACTGGTGCTGGTGGCCGTGGTGAGCCACTACGGCA
CCGGGCGGCTGCGCAACCTGGCGGTGACGCTCTCCCGCCTGGAAGTGGACCGGGCGCTGGAGGCCCGCCGCTTCCAGGAA
GTGGAGGAGGCGCGCCGCACGATTGAGCGCATGCTGGCGGACGCCCAGGCACAGAACGCCGAACTGCAGCGGCTGCAACG
GGACAAGGAACAGCTCACCGAGTTCCTGGTCCACGACCTGCGCTCGCCCCTTTCGGCGCTGACGCTGTCCTTGTCGTGGA
TGGAGCAGGAGGTGCCCCAGCAGGGCATCCTCGGCGAGTCCGTCCGCACAGGGCTGGCCGTCACCGCGCGGTTGGACCGG
ATGATTTCCGACCTCATGGACGTGCCCCGCCTGGAGGAAGGCCGGCTGGAGCCGCAGCGGGCCACCTTCCCCGCCACGCG
CATCGTGGAAGACGTGCGCCGCTCCCTGGAGAGCGTGGCCCGCGCGCGCAAGCTCACCCTGGACGCGGAGGTCCCCGTCC
AACTGGAGCTGGAGGGCGACGCCGACCTGCTGGTCCGCGTCCTGGAGAACCTCACCACCAATGCCCTGCGCTACGCCCCG
TCGGGCGGGAGGGTGCGCCTGGAAGCCGGCGCGGATGTGAACGGCCGCTGGCTCGCGGTGCGCAACGACGGCCCGCCCAT
CTCCGAAGAGGCGCGCGGGCGCATCTTCGACAAGTATGAGCAGGCCGACGCGGAGCGGGACAGCCGCCGTGGCTACGGCC
TGGGGCTCTACTTCTGCCGGCTCGCCGCGGAGGCCCACGGCGGGCGGTTGGCGGTGGAGGACGCGCCCGGATGGTCCACG
TCCTTCGTGCTGCGGCTGCCGGCCTGA

Upstream 100 bases:

>100_bases
AAGCAGACACAGTCCCAATGTCTTCTCAGTGCTTACGCGCTTCTACCTAAGGCGATTGCGGCGTTTCCAAAAGCGTGACG
TGACGGTTCCACGTCGGAAA

Downstream 100 bases:

>100_bases
GCCTCAGCCGCTGCGCGCCTTCTTCTGGCGGCGCTTGAGGATGCGCGCCACCTGCGCGTTCGCGTTCGCCAGGACGGAGG
GCGCGTCCAACGTGGTGAGC

Product: sensor histidine kinase

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A [H]

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MEPARATPARPSASARQAAGLASHEGSRENPRLVTSPPPVSGPLEETMSRAMDAQRRSVVGAGAAVRLVGAALFLAISTT
LWLAGGRDWGVYPPALGLYASVAGVLFMLRQRRVARGLGAVQSLVDVGLVYWIQSTTLLVSPFPAGVAGFSLGLFALVVA
LSGLGMRGTVVYGTALLSAVAQAALMRQASVGWGAVAIAVVALVLVAVVSHYGTGRLRNLAVTLSRLEVDRALEARRFQE
VEEARRTIERMLADAQAQNAELQRLQRDKEQLTEFLVHDLRSPLSALTLSLSWMEQEVPQQGILGESVRTGLAVTARLDR
MISDLMDVPRLEEGRLEPQRATFPATRIVEDVRRSLESVARARKLTLDAEVPVQLELEGDADLLVRVLENLTTNALRYAP
SGGRVRLEAGADVNGRWLAVRNDGPPISEEARGRIFDKYEQADAERDSRRGYGLGLYFCRLAAEAHGGRLAVEDAPGWST
SFVLRLPA

Sequences:

>Translated_488_residues
MEPARATPARPSASARQAAGLASHEGSRENPRLVTSPPPVSGPLEETMSRAMDAQRRSVVGAGAAVRLVGAALFLAISTT
LWLAGGRDWGVYPPALGLYASVAGVLFMLRQRRVARGLGAVQSLVDVGLVYWIQSTTLLVSPFPAGVAGFSLGLFALVVA
LSGLGMRGTVVYGTALLSAVAQAALMRQASVGWGAVAIAVVALVLVAVVSHYGTGRLRNLAVTLSRLEVDRALEARRFQE
VEEARRTIERMLADAQAQNAELQRLQRDKEQLTEFLVHDLRSPLSALTLSLSWMEQEVPQQGILGESVRTGLAVTARLDR
MISDLMDVPRLEEGRLEPQRATFPATRIVEDVRRSLESVARARKLTLDAEVPVQLELEGDADLLVRVLENLTTNALRYAP
SGGRVRLEAGADVNGRWLAVRNDGPPISEEARGRIFDKYEQADAERDSRRGYGLGLYFCRLAAEAHGGRLAVEDAPGWST
SFVLRLPA
>Mature_488_residues
MEPARATPARPSASARQAAGLASHEGSRENPRLVTSPPPVSGPLEETMSRAMDAQRRSVVGAGAAVRLVGAALFLAISTT
LWLAGGRDWGVYPPALGLYASVAGVLFMLRQRRVARGLGAVQSLVDVGLVYWIQSTTLLVSPFPAGVAGFSLGLFALVVA
LSGLGMRGTVVYGTALLSAVAQAALMRQASVGWGAVAIAVVALVLVAVVSHYGTGRLRNLAVTLSRLEVDRALEARRFQE
VEEARRTIERMLADAQAQNAELQRLQRDKEQLTEFLVHDLRSPLSALTLSLSWMEQEVPQQGILGESVRTGLAVTARLDR
MISDLMDVPRLEEGRLEPQRATFPATRIVEDVRRSLESVARARKLTLDAEVPVQLELEGDADLLVRVLENLTTNALRYAP
SGGRVRLEAGADVNGRWLAVRNDGPPISEEARGRIFDKYEQADAERDSRRGYGLGLYFCRLAAEAHGGRLAVEDAPGWST
SFVLRLPA

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=306, Percent_Identity=25.1633986928105, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788393, Length=237, Percent_Identity=27.0042194092827, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87082128, Length=341, Percent_Identity=26.6862170087977, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788713, Length=295, Percent_Identity=23.728813559322, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788279, Length=300, Percent_Identity=25, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=29.1304347826087, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786912, Length=249, Percent_Identity=26.9076305220884, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786600, Length=232, Percent_Identity=24.1379310344828, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789149, Length=264, Percent_Identity=26.5151515151515, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI145693157, Length=216, Percent_Identity=25.9259259259259, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=26.271186440678, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790551, Length=215, Percent_Identity=28.3720930232558, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787894, Length=218, Percent_Identity=31.1926605504587, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 52650; Mature: 52650

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPARATPARPSASARQAAGLASHEGSRENPRLVTSPPPVSGPLEETMSRAMDAQRRSVV
CCCCCCCCCCCCCHHHHHHCCHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHH
GAGAAVRLVGAALFLAISTTLWLAGGRDWGVYPPALGLYASVAGVLFMLRQRRVARGLGA
CCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VQSLVDVGLVYWIQSTTLLVSPFPAGVAGFSLGLFALVVALSGLGMRGTVVYGTALLSAV
HHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AQAALMRQASVGWGAVAIAVVALVLVAVVSHYGTGRLRNLAVTLSRLEVDRALEARRFQE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VEEARRTIERMLADAQAQNAELQRLQRDKEQLTEFLVHDLRSPLSALTLSLSWMEQEVPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QGILGESVRTGLAVTARLDRMISDLMDVPRLEEGRLEPQRATFPATRIVEDVRRSLESVA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RARKLTLDAEVPVQLELEGDADLLVRVLENLTTNALRYAPSGGRVRLEAGADVNGRWLAV
HHHHHEECCCCCEEEEECCCHHHHHHHHHHHHHHHHEECCCCCEEEEECCCCCCCCEEEE
RNDGPPISEEARGRIFDKYEQADAERDSRRGYGLGLYFCRLAAEAHGGRLAVEDAPGWST
CCCCCCCCHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCC
SFVLRLPA
EEEEECCC
>Mature Secondary Structure
MEPARATPARPSASARQAAGLASHEGSRENPRLVTSPPPVSGPLEETMSRAMDAQRRSVV
CCCCCCCCCCCCCHHHHHHCCHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHH
GAGAAVRLVGAALFLAISTTLWLAGGRDWGVYPPALGLYASVAGVLFMLRQRRVARGLGA
CCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VQSLVDVGLVYWIQSTTLLVSPFPAGVAGFSLGLFALVVALSGLGMRGTVVYGTALLSAV
HHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AQAALMRQASVGWGAVAIAVVALVLVAVVSHYGTGRLRNLAVTLSRLEVDRALEARRFQE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VEEARRTIERMLADAQAQNAELQRLQRDKEQLTEFLVHDLRSPLSALTLSLSWMEQEVPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QGILGESVRTGLAVTARLDRMISDLMDVPRLEEGRLEPQRATFPATRIVEDVRRSLESVA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RARKLTLDAEVPVQLELEGDADLLVRVLENLTTNALRYAPSGGRVRLEAGADVNGRWLAV
HHHHHEECCCCCEEEEECCCHHHHHHHHHHHHHHHHEECCCCCEEEEECCCCCCCCEEEE
RNDGPPISEEARGRIFDKYEQADAERDSRRGYGLGLYFCRLAAEAHGGRLAVEDAPGWST
CCCCCCCCHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCC
SFVLRLPA
EEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA