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The map label for this gene is lspA [H]

Identifier: 108761376

GI number: 108761376

Start: 4729395

End: 4729922

Strand: Direct

Name: lspA [H]

Synonym: MXAN_3930

Alternate gene names: 108761376

Gene position: 4729395-4729922 (Clockwise)

Preceding gene: 108763573

Following gene: 108763293

Centisome position: 51.75

GC content: 67.8

Gene sequence:

>528_bases
ATGACTCCGGAGCGTCGAAAGTACCTTGTCGTGGGCGGGCTGGCCACGCTGTTGCTCATCCTCGACCAATGGACGAAGGT
CCTGGTCCGCGAGCACGTGAAGCCCCTGGGCTACACCGGCATGAGCGTCTTCGGCGACGTCATCCGCTTCCAGTACGTGG
AGAACACCGGCATCACCTTCGGCATGTTCCGGTCGCTGCCCTACGCCCAGCTCATCCTCAGCGCGGTGGCCATCCCCGTC
TTCCTGCTGGTCATCCACCTGGTCCGCCAGACGCCCGCGGACCACTACCGGCTGCACGTCGCGCTCGGCCTCGTCGGCGC
CGGCGTCGGCAACCTGATTGACCGCGTCCGCCTGGGCAGCGTGACGGACTTCGTCGTCGCTGACTTCGGGTTCTGGCCGG
TGAACCCCTGGTATGCCTTCAACGTCGCGGACGCCGCGCTCGTCGTCGGCGCCATCTTGATGGCCTTCGACTCCCGCCGT
CCGCAGCCGGCCCCTGCGCCCGCTCCCGCTCCGAGCCAGGACGACTAG

Upstream 100 bases:

>100_bases
AACTCGGTCTGCCAGTGGCCCTGCGAGCACGATGTGCATCCGCTCGCCGACACTCCCGGTGGTTGTCCGGCCACCTCATT
TGTAGGAGGCTGCGCCGCAA

Downstream 100 bases:

>100_bases
CCAGGACGTGGGCGCGAGAGCGGGCCACCGCTCGCGCGCCCCCTTGGCGCACCATCCGCATCACGCCATGGCAGCGGCGG
CCCGCGCCTGCTCGCCAGCA

Product: signal peptidase II

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MTPERRKYLVVGGLATLLLILDQWTKVLVREHVKPLGYTGMSVFGDVIRFQYVENTGITFGMFRSLPYAQLILSAVAIPV
FLLVIHLVRQTPADHYRLHVALGLVGAGVGNLIDRVRLGSVTDFVVADFGFWPVNPWYAFNVADAALVVGAILMAFDSRR
PQPAPAPAPAPSQDD

Sequences:

>Translated_175_residues
MTPERRKYLVVGGLATLLLILDQWTKVLVREHVKPLGYTGMSVFGDVIRFQYVENTGITFGMFRSLPYAQLILSAVAIPV
FLLVIHLVRQTPADHYRLHVALGLVGAGVGNLIDRVRLGSVTDFVVADFGFWPVNPWYAFNVADAALVVGAILMAFDSRR
PQPAPAPAPAPSQDD
>Mature_174_residues
TPERRKYLVVGGLATLLLILDQWTKVLVREHVKPLGYTGMSVFGDVIRFQYVENTGITFGMFRSLPYAQLILSAVAIPVF
LLVIHLVRQTPADHYRLHVALGLVGAGVGNLIDRVRLGSVTDFVVADFGFWPVNPWYAFNVADAALVVGAILMAFDSRRP
QPAPAPAPAPSQDD

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 19201; Mature: 19070

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPERRKYLVVGGLATLLLILDQWTKVLVREHVKPLGYTGMSVFGDVIRFQYVENTGITF
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHH
GMFRSLPYAQLILSAVAIPVFLLVIHLVRQTPADHYRLHVALGLVGAGVGNLIDRVRLGS
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHCCC
VTDFVVADFGFWPVNPWYAFNVADAALVVGAILMAFDSRRPQPAPAPAPAPSQDD
HHHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TPERRKYLVVGGLATLLLILDQWTKVLVREHVKPLGYTGMSVFGDVIRFQYVENTGITF
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHH
GMFRSLPYAQLILSAVAIPVFLLVIHLVRQTPADHYRLHVALGLVGAGVGNLIDRVRLGS
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHCCC
VTDFVVADFGFWPVNPWYAFNVADAALVVGAILMAFDSRRPQPAPAPAPAPSQDD
HHHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA