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The map label for this gene is 108763573

Identifier: 108763573

GI number: 108763573

Start: 4723483

End: 4725063

Strand: Direct

Name: 108763573

Synonym: MXAN_3925

Alternate gene names: NA

Gene position: 4723483-4725063 (Clockwise)

Preceding gene: 108757074

Following gene: 108761376

Centisome position: 51.68

GC content: 69.51

Gene sequence:

>1581_bases
TTGACAACCATGAGGCTGTGTATCGTCGGAAGTGGTGTTGCCGCGGTCATCACCGCCCGCGCCGCGCTGGAGCGGGGCTA
CGAGGTGGTGATGCTCGAAGCCGGCCCTCGCACGCCCATGCGGGACTCGCGCCGCTGGCTGGACTTCGTCACCACGGGCG
TGCGGCCCTACCACGCCTGTGAGGACTCGCAGGGTGACGCCAACTCCCGCCCCGGTGTCCAACCCGAGCGCGACCACTTC
CTCATCAAGGGCAGCCGGCTCATGGCGGTGGGCGGGTCGACGCTGCACTGGAGCGGCTGGACGCCCCGCCTCCAGCCCGA
GGACCTGGAGCTGCGCAAGCGCACCGGCAAGGGGAACGACTGGCCCTTCAGCTACACCCAGCTCGAGCCCTATTACAGCC
AGGCTGAGTCCCTGCTGAACGTCACCGGCCCCAACGCGCCCGTGGACGGACATCCCACGCCCTGGCGCTCGCAGCCCTAC
AAGTGGAACAGCCCGCCGTATCCCATCGAGTCGGAGCCGGTGCGCCACGCCTTGAAGGCGCTGGGCATCACCTATGACCA
CATTCCCATGTCGCGCAGAGGCCCCGGCGGCGAGGGTGTGGGCGGCCCGTGCATGACGTTTGGCACGTGCCGGTATTGCC
CGATGGGCGCGCGCTTCGACCCCACCCTGCTGCTGGCGGACATGGAGTCCCATCCGGGCTTCCGGTTGCTCGCGAGCAGC
CCGGTGCTGGCCGTGCGCATGGCGGGAGCGGTGGCCCAGGGCGTCACCTACCGCACCCCCGAGGGCGAGACGGCCACGCT
GGACGCGGACGCCGTGCTGGTGGCCGCGGGCGCCCTGGAGACGCCCAAGCTGCTGTGGCACTCGGGCTTCGATGAGCAGC
GCCTGCCCGCGCTCGGGCGCTACCTGGTTACCCACCCGATGCTGAAGCTCGAGGGCAAGCTGGCAAAGCCCCCCCGGGAG
TTCAACGGGCGCGAAGTCCCCATGCCCGCCCTCTTCTCTCGGCACTTCGACACGCCGGAGCAGCAGGCCGCCGGGAAGAT
GATCTTCTCCGAGTACCCGGAGGAGCCGGACCTGCAGTCATGGGTCCGCCAGGAGCAACTGGCGCCCGAGTACATCGCCT
CCTTCGCCCGGGAGAGCCGGCTCAACCTCCATGGCTTCATCGAGGAGTTCCCCCAGGCGGAGAACCGCCTGCGCTTCACG
GGCAAGCCGGGCGAGCGCCAGGTGGAGATTCACTACGCGGTGGACGCGGGGTTCGCCGCGCGCTGGCAGTGGATGACCGA
CACCTTGATGCAGGTGATGAAGACCGCGGGCTGCCGCGAGTCGGAGGTCTGGGTTTCGGGCGTGATTCGCCGGGCGGACC
ACTCGGTGGGCACGGCGCGCTTCGGCCAAGGGCCGGACTCGGGCGTCGTGGACGGGAGGCACCTCGTCTTCGGGACGAAG
AACCTGTTCGCCCTCACCAACGGCAACTTCCCGAACAACGGCGCCATCAACCCGACGCTGACGCTCACCGCCCTCTCGCT
GCGCTTCGCGGACCAGGTGCTGCCGGACCTGGCGCCGACACGAACTACAGCGCGGCCTTGA

Upstream 100 bases:

>100_bases
AACATGAATGGCCACATGGGCGGGCTCTGGCACGAGCCGCACGAATCGGGCTCCTATCACGCCTCGGACGAACTGTAGTC
AGCGCGGTCGCCGACAGGAT

Downstream 100 bases:

>100_bases
GCACGGCCAACGCGACGATGGCCACGACGGCGAACACCTCGCGTCGCGCGGGCGCCTCCTGGATGAAGGCGTTGGCGAAC
ACCAGGGAGAAGAGCGTCAC

Product: GMC oxidoreductase

Products: NA

Alternate protein names: GA 2-DH dehydrogenase subunit; GADH dehydrogenase subunit [H]

Number of amino acids: Translated: 526; Mature: 525

Protein sequence:

>526_residues
MTTMRLCIVGSGVAAVITARAALERGYEVVMLEAGPRTPMRDSRRWLDFVTTGVRPYHACEDSQGDANSRPGVQPERDHF
LIKGSRLMAVGGSTLHWSGWTPRLQPEDLELRKRTGKGNDWPFSYTQLEPYYSQAESLLNVTGPNAPVDGHPTPWRSQPY
KWNSPPYPIESEPVRHALKALGITYDHIPMSRRGPGGEGVGGPCMTFGTCRYCPMGARFDPTLLLADMESHPGFRLLASS
PVLAVRMAGAVAQGVTYRTPEGETATLDADAVLVAAGALETPKLLWHSGFDEQRLPALGRYLVTHPMLKLEGKLAKPPRE
FNGREVPMPALFSRHFDTPEQQAAGKMIFSEYPEEPDLQSWVRQEQLAPEYIASFARESRLNLHGFIEEFPQAENRLRFT
GKPGERQVEIHYAVDAGFAARWQWMTDTLMQVMKTAGCRESEVWVSGVIRRADHSVGTARFGQGPDSGVVDGRHLVFGTK
NLFALTNGNFPNNGAINPTLTLTALSLRFADQVLPDLAPTRTTARP

Sequences:

>Translated_526_residues
MTTMRLCIVGSGVAAVITARAALERGYEVVMLEAGPRTPMRDSRRWLDFVTTGVRPYHACEDSQGDANSRPGVQPERDHF
LIKGSRLMAVGGSTLHWSGWTPRLQPEDLELRKRTGKGNDWPFSYTQLEPYYSQAESLLNVTGPNAPVDGHPTPWRSQPY
KWNSPPYPIESEPVRHALKALGITYDHIPMSRRGPGGEGVGGPCMTFGTCRYCPMGARFDPTLLLADMESHPGFRLLASS
PVLAVRMAGAVAQGVTYRTPEGETATLDADAVLVAAGALETPKLLWHSGFDEQRLPALGRYLVTHPMLKLEGKLAKPPRE
FNGREVPMPALFSRHFDTPEQQAAGKMIFSEYPEEPDLQSWVRQEQLAPEYIASFARESRLNLHGFIEEFPQAENRLRFT
GKPGERQVEIHYAVDAGFAARWQWMTDTLMQVMKTAGCRESEVWVSGVIRRADHSVGTARFGQGPDSGVVDGRHLVFGTK
NLFALTNGNFPNNGAINPTLTLTALSLRFADQVLPDLAPTRTTARP
>Mature_525_residues
TTMRLCIVGSGVAAVITARAALERGYEVVMLEAGPRTPMRDSRRWLDFVTTGVRPYHACEDSQGDANSRPGVQPERDHFL
IKGSRLMAVGGSTLHWSGWTPRLQPEDLELRKRTGKGNDWPFSYTQLEPYYSQAESLLNVTGPNAPVDGHPTPWRSQPYK
WNSPPYPIESEPVRHALKALGITYDHIPMSRRGPGGEGVGGPCMTFGTCRYCPMGARFDPTLLLADMESHPGFRLLASSP
VLAVRMAGAVAQGVTYRTPEGETATLDADAVLVAAGALETPKLLWHSGFDEQRLPALGRYLVTHPMLKLEGKLAKPPREF
NGREVPMPALFSRHFDTPEQQAAGKMIFSEYPEEPDLQSWVRQEQLAPEYIASFARESRLNLHGFIEEFPQAENRLRFTG
KPGERQVEIHYAVDAGFAARWQWMTDTLMQVMKTAGCRESEVWVSGVIRRADHSVGTARFGQGPDSGVVDGRHLVFGTKN
LFALTNGNFPNNGAINPTLTLTALSLRFADQVLPDLAPTRTTARP

Specific function: Part of the heterotrimer that catalyzes the conversion of D-gluconate to 2-dehydro-D-gluconate. This subunit functions as the dehydrogenase [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.3 [H]

Molecular weight: Translated: 58191; Mature: 58060

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS00221 MIP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTMRLCIVGSGVAAVITARAALERGYEVVMLEAGPRTPMRDSRRWLDFVTTGVRPYHAC
CCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
EDSQGDANSRPGVQPERDHFLIKGSRLMAVGGSTLHWSGWTPRLQPEDLELRKRTGKGND
CCCCCCCCCCCCCCCCCCEEEEECCEEEEECCCEEEECCCCCCCCCCCHHHHHHCCCCCC
WPFSYTQLEPYYSQAESLLNVTGPNAPVDGHPTPWRSQPYKWNSPPYPIESEPVRHALKA
CCCEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
LGITYDHIPMSRRGPGGEGVGGPCMTFGTCRYCPMGARFDPTLLLADMESHPGFRLLASS
HCCCEECCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECC
PVLAVRMAGAVAQGVTYRTPEGETATLDADAVLVAAGALETPKLLWHSGFDEQRLPALGR
CEEEHHHHHHHHCCCEEECCCCCEEEECCCEEEEECCCCCCCHHHHHCCCCHHHHHHHHH
YLVTHPMLKLEGKLAKPPREFNGREVPMPALFSRHFDTPEQQAAGKMIFSEYPEEPDLQS
HHHHCCHHEECCCCCCCCHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHH
WVRQEQLAPEYIASFARESRLNLHGFIEEFPQAENRLRFTGKPGERQVEIHYAVDAGFAA
HHHHHHCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEECCCCCCEEEEEEEEECCCCHH
RWQWMTDTLMQVMKTAGCRESEVWVSGVIRRADHSVGTARFGQGPDSGVVDGRHLVFGTK
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECC
NLFALTNGNFPNNGAINPTLTLTALSLRFADQVLPDLAPTRTTARP
CEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TTMRLCIVGSGVAAVITARAALERGYEVVMLEAGPRTPMRDSRRWLDFVTTGVRPYHAC
CCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
EDSQGDANSRPGVQPERDHFLIKGSRLMAVGGSTLHWSGWTPRLQPEDLELRKRTGKGND
CCCCCCCCCCCCCCCCCCEEEEECCEEEEECCCEEEECCCCCCCCCCCHHHHHHCCCCCC
WPFSYTQLEPYYSQAESLLNVTGPNAPVDGHPTPWRSQPYKWNSPPYPIESEPVRHALKA
CCCEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
LGITYDHIPMSRRGPGGEGVGGPCMTFGTCRYCPMGARFDPTLLLADMESHPGFRLLASS
HCCCEECCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECC
PVLAVRMAGAVAQGVTYRTPEGETATLDADAVLVAAGALETPKLLWHSGFDEQRLPALGR
CEEEHHHHHHHHCCCEEECCCCCEEEECCCEEEEECCCCCCCHHHHHCCCCHHHHHHHHH
YLVTHPMLKLEGKLAKPPREFNGREVPMPALFSRHFDTPEQQAAGKMIFSEYPEEPDLQS
HHHHCCHHEECCCCCCCCHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHH
WVRQEQLAPEYIASFARESRLNLHGFIEEFPQAENRLRFTGKPGERQVEIHYAVDAGFAA
HHHHHHCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEECCCCCCEEEEEEEEECCCCHH
RWQWMTDTLMQVMKTAGCRESEVWVSGVIRRADHSVGTARFGQGPDSGVVDGRHLVFGTK
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECC
NLFALTNGNFPNNGAINPTLTLTALSLRFADQVLPDLAPTRTTARP
CEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9352901 [H]