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The map label for this gene is zraR [H]

Identifier: 108761339

GI number: 108761339

Start: 2910288

End: 2911928

Strand: Reverse

Name: zraR [H]

Synonym: MXAN_2501

Alternate gene names: 108761339

Gene position: 2911928-2910288 (Counterclockwise)

Preceding gene: 108758914

Following gene: 108762144

Centisome position: 31.86

GC content: 70.99

Gene sequence:

>1641_bases
ATGCCGGAGCTGGTGTTCTTTCGTCGTGGCGAGGAGGTGTTGCGGGTGGGGGTGGACCGGGCACGGCTGGTGCTCGGACG
CGGCGAGCAGAGCGACGTCGCCATCCCAGACCCCGAGGTGAGCCGCCTCCAGGTCGCGTTGCTGTGGGACGGCGAGCGCT
GCCGGGTGGAGGATTTGTCCGGCAAGGGCACCACCGTCGCCGGCCAGTCCATCACCCACGGCGAGCTGCCAGACGGCGCG
GACCTGGCGCTGGGCCAATGGCGCGCGGTGTTCCGCATCAGCGGCGGCAGCGAAGGCGCGGACGTCACCACCGAGGTGGG
CCACACGACGTCCGTCCAGTCCCGCGACACGCAGGCCCCGCGCTGGCAGCCCGCGCAGGTGCGGGTGAAGCAGGGCCTCA
ATGAGTCCGTGCACCGCTTCACGGGTGAAGGCTTCACCGCGGGCAAGGACGCCGGCTGCGACCTGGTGCTCCAGGACCGC
TTCGCCTCCAGCCGGCACCTGAAGGTGACCCGGCGCGACAACACCTTCCACGTCGTGGACCTGCGCTCCACCAACGGGAC
GTGGATGGGCCCGGTGCGCGTCTTCGAGGCGGAAGTCCCGCTGCCCACCGTGCTGCGCGTGGGTGAGACGGAGCTGGTGC
TGGAGCCTGCCGCGCCCACCACGCGCAAGGAGCCCACGTCCTTCCACGGCATCATCGGCGGCGACCCGTCGGTGCGGCAG
CTCTCGGAGTTGATTGAGCGGGTGGCCCCGTCCTCCGCGGCGGTGACGATTCTGGGCGAGTCCGGCACCGGCAAGGAGCT
GGTGGCCCGCGCCATCCACGCCTGCTCGCAGCGGGCGAACCGGCCGCTGGTGCCCGTCAACTGCGCGGCCATCTCCAAGG
AGCTCATCGAGAGCGAGCTCTTCGGCCATGAGAAGGGTTCCTTCACCGGCGCCATGGGCGCGCGCAAGGGCGCCTTCGAG
GAGGCCGACGGAGGCACCCTCTTCCTGGACGAGATTGGCGAGCTGCCGCTGGACTTGCAGGCCAAGCTGCTGCGCGCGCT
GGAAGGCGGCGAAATCAAGCGCGTGGGCGCCAGCCGCCCGCAGACGGTGGACGTGCGCGTGGTGGCGGCCACCAACAGGG
ACTTGCTGGCGGCGGCGCGCGAGGGCCGCTTCCGCGAGGACCTGTACTACCGGCTCTGTGTCATCCCCCTGCACCTGCCG
CCGCTGCGCAGCCGTAAGGCGGACCTGGGCTCACTGGCCGAGCACTTCGTGCGCACCTACGCCCCGCGTGGCCAGTCCGT
GCGCTTCACACCCGCGGCCCTGGAGCGGCTCCAGCACCACGCGTGGCCGGGCAACATCCGCGAGCTGCGCAACGTGGTGC
ACCGCGCGCTGCTGCTGCGCAAGGGGCCCCTCATCGACGCGGGGGACATCTCCTTCGACCAGGAGCTGAACCGCGAGACG
GGCATCGCCGTGCCGGAGCTGCCGCCGGGGATGACGCTGGAGCAGATGCTGGAGAAGCTGGAGCGTCAAATCGTCGAGGC
GGCGCTGCGGCGGTACAACAACAACCGCGAGCGCGTGGCCCGCGAGTTGGGCGTGGCCCGCTCCACCCTCTTCAAGCGGC
TGAAGGACTGGGGCCTCACGAAGCAGGACGAGCAGGAGTAG

Upstream 100 bases:

>100_bases
AGCGCCCGCTCCCCCGCGCCCTCCTCCGGGCGCGGGGTTGAAAGCCGAACACCAGGGCGTGTAAAGCGCTCTCAGGCGCT
GGACTGCTGAGAGGGCTGGG

Downstream 100 bases:

>100_bases
AGGCCGTCTTCCAGGGAGGTGGGGGTGTCAGCGGATGGACGCCCCCGCCCCGGGAAAATGTGGCCCACGGTGCATGGCCC
TGAAGGGCGATAGACCCTTC

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MPELVFFRRGEEVLRVGVDRARLVLGRGEQSDVAIPDPEVSRLQVALLWDGERCRVEDLSGKGTTVAGQSITHGELPDGA
DLALGQWRAVFRISGGSEGADVTTEVGHTTSVQSRDTQAPRWQPAQVRVKQGLNESVHRFTGEGFTAGKDAGCDLVLQDR
FASSRHLKVTRRDNTFHVVDLRSTNGTWMGPVRVFEAEVPLPTVLRVGETELVLEPAAPTTRKEPTSFHGIIGGDPSVRQ
LSELIERVAPSSAAVTILGESGTGKELVARAIHACSQRANRPLVPVNCAAISKELIESELFGHEKGSFTGAMGARKGAFE
EADGGTLFLDEIGELPLDLQAKLLRALEGGEIKRVGASRPQTVDVRVVAATNRDLLAAAREGRFREDLYYRLCVIPLHLP
PLRSRKADLGSLAEHFVRTYAPRGQSVRFTPAALERLQHHAWPGNIRELRNVVHRALLLRKGPLIDAGDISFDQELNRET
GIAVPELPPGMTLEQMLEKLERQIVEAALRRYNNNRERVARELGVARSTLFKRLKDWGLTKQDEQE

Sequences:

>Translated_546_residues
MPELVFFRRGEEVLRVGVDRARLVLGRGEQSDVAIPDPEVSRLQVALLWDGERCRVEDLSGKGTTVAGQSITHGELPDGA
DLALGQWRAVFRISGGSEGADVTTEVGHTTSVQSRDTQAPRWQPAQVRVKQGLNESVHRFTGEGFTAGKDAGCDLVLQDR
FASSRHLKVTRRDNTFHVVDLRSTNGTWMGPVRVFEAEVPLPTVLRVGETELVLEPAAPTTRKEPTSFHGIIGGDPSVRQ
LSELIERVAPSSAAVTILGESGTGKELVARAIHACSQRANRPLVPVNCAAISKELIESELFGHEKGSFTGAMGARKGAFE
EADGGTLFLDEIGELPLDLQAKLLRALEGGEIKRVGASRPQTVDVRVVAATNRDLLAAAREGRFREDLYYRLCVIPLHLP
PLRSRKADLGSLAEHFVRTYAPRGQSVRFTPAALERLQHHAWPGNIRELRNVVHRALLLRKGPLIDAGDISFDQELNRET
GIAVPELPPGMTLEQMLEKLERQIVEAALRRYNNNRERVARELGVARSTLFKRLKDWGLTKQDEQE
>Mature_545_residues
PELVFFRRGEEVLRVGVDRARLVLGRGEQSDVAIPDPEVSRLQVALLWDGERCRVEDLSGKGTTVAGQSITHGELPDGAD
LALGQWRAVFRISGGSEGADVTTEVGHTTSVQSRDTQAPRWQPAQVRVKQGLNESVHRFTGEGFTAGKDAGCDLVLQDRF
ASSRHLKVTRRDNTFHVVDLRSTNGTWMGPVRVFEAEVPLPTVLRVGETELVLEPAAPTTRKEPTSFHGIIGGDPSVRQL
SELIERVAPSSAAVTILGESGTGKELVARAIHACSQRANRPLVPVNCAAISKELIESELFGHEKGSFTGAMGARKGAFEE
ADGGTLFLDEIGELPLDLQAKLLRALEGGEIKRVGASRPQTVDVRVVAATNRDLLAAAREGRFREDLYYRLCVIPLHLPP
LRSRKADLGSLAEHFVRTYAPRGQSVRFTPAALERLQHHAWPGNIRELRNVVHRALLLRKGPLIDAGDISFDQELNRETG
IAVPELPPGMTLEQMLEKLERQIVEAALRRYNNNRERVARELGVARSTLFKRLKDWGLTKQDEQE

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=311, Percent_Identity=48.5530546623794, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1788550, Length=316, Percent_Identity=45.8860759493671, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI1789233, Length=319, Percent_Identity=45.141065830721, Blast_Score=261, Evalue=8e-71,
Organism=Escherichia coli, GI87082117, Length=326, Percent_Identity=45.0920245398773, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1789087, Length=323, Percent_Identity=44.2724458204334, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI1790299, Length=332, Percent_Identity=44.578313253012, Blast_Score=248, Evalue=5e-67,
Organism=Escherichia coli, GI87082152, Length=321, Percent_Identity=46.417445482866, Blast_Score=242, Evalue=5e-65,
Organism=Escherichia coli, GI1786524, Length=326, Percent_Identity=45.398773006135, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1788905, Length=335, Percent_Identity=40, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1787583, Length=332, Percent_Identity=37.3493975903614, Blast_Score=214, Evalue=8e-57,
Organism=Escherichia coli, GI87081872, Length=320, Percent_Identity=40.9375, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1789828, Length=263, Percent_Identity=38.7832699619772, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI87081858, Length=321, Percent_Identity=30.2180685358255, Blast_Score=139, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 60136; Mature: 60005

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS50006 FHA_DOMAIN ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPELVFFRRGEEVLRVGVDRARLVLGRGEQSDVAIPDPEVSRLQVALLWDGERCRVEDLS
CCCEEEEECCHHHHHHCCCHHEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCEEEECC
GKGTTVAGQSITHGELPDGADLALGQWRAVFRISGGSEGADVTTEVGHTTSVQSRDTQAP
CCCCEEECCCCCCCCCCCCCCCHHCCCEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCC
RWQPAQVRVKQGLNESVHRFTGEGFTAGKDAGCDLVLQDRFASSRHLKVTRRDNTFHVVD
CCCHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCEEEEECCCEEEEEE
LRSTNGTWMGPVRVFEAEVPLPTVLRVGETELVLEPAAPTTRKEPTSFHGIIGGDPSVRQ
EECCCCCEECCEEEEECCCCCHHHEECCCCEEEEECCCCCCCCCCCCCCCEECCCCCHHH
LSELIERVAPSSAAVTILGESGTGKELVARAIHACSQRANRPLVPVNCAAISKELIESEL
HHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHH
FGHEKGSFTGAMGARKGAFEEADGGTLFLDEIGELPLDLQAKLLRALEGGEIKRVGASRP
HCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHCCCCCHHHHHHHHHHCCCCEEECCCCCC
QTVDVRVVAATNRDLLAAAREGRFREDLYYRLCVIPLHLPPLRSRKADLGSLAEHFVRTY
CEEEEEEEEECCCHHHHHHHCCCHHHHHEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHH
APRGQSVRFTPAALERLQHHAWPGNIRELRNVVHRALLLRKGPLIDAGDISFDQELNRET
CCCCCCEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCHHC
GIAVPELPPGMTLEQMLEKLERQIVEAALRRYNNNRERVARELGVARSTLFKRLKDWGLT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
KQDEQE
CCCCCC
>Mature Secondary Structure 
PELVFFRRGEEVLRVGVDRARLVLGRGEQSDVAIPDPEVSRLQVALLWDGERCRVEDLS
CCEEEEECCHHHHHHCCCHHEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCEEEECC
GKGTTVAGQSITHGELPDGADLALGQWRAVFRISGGSEGADVTTEVGHTTSVQSRDTQAP
CCCCEEECCCCCCCCCCCCCCCHHCCCEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCC
RWQPAQVRVKQGLNESVHRFTGEGFTAGKDAGCDLVLQDRFASSRHLKVTRRDNTFHVVD
CCCHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCEEEEECCCEEEEEE
LRSTNGTWMGPVRVFEAEVPLPTVLRVGETELVLEPAAPTTRKEPTSFHGIIGGDPSVRQ
EECCCCCEECCEEEEECCCCCHHHEECCCCEEEEECCCCCCCCCCCCCCCEECCCCCHHH
LSELIERVAPSSAAVTILGESGTGKELVARAIHACSQRANRPLVPVNCAAISKELIESEL
HHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHH
FGHEKGSFTGAMGARKGAFEEADGGTLFLDEIGELPLDLQAKLLRALEGGEIKRVGASRP
HCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHCCCCCHHHHHHHHHHCCCCEEECCCCCC
QTVDVRVVAATNRDLLAAAREGRFREDLYYRLCVIPLHLPPLRSRKADLGSLAEHFVRTY
CEEEEEEEEECCCHHHHHHHCCCHHHHHEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHH
APRGQSVRFTPAALERLQHHAWPGNIRELRNVVHRALLLRKGPLIDAGDISFDQELNRET
CCCCCCEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCHHC
GIAVPELPPGMTLEQMLEKLERQIVEAALRRYNNNRERVARELGVARSTLFKRLKDWGLT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
KQDEQE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]