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The map label for this gene is crp [C]

Identifier: 108761303

GI number: 108761303

Start: 2291282

End: 2291740

Strand: Reverse

Name: crp [C]

Synonym: MXAN_1953

Alternate gene names: 108761303

Gene position: 2291740-2291282 (Counterclockwise)

Preceding gene: 108760398

Following gene: 108763923

Centisome position: 25.07

GC content: 64.27

Gene sequence:

>459_bases
ATGGATGCCGCAGTCCTCAAGAAGGTTGCGCTGTTCGAGGGTTTGACCCAGGGACAGCTCGCCAAGGTCGCCCAGATTGG
CCACTCCCGGACCTACCCGGCGGGCGCCTTTCTGTTCCGTGAGGGGGAAACCGGCCAGGAGATGTTCGTAATCGCCGAGG
GCAAGGTCCGCATCTCCAAGTCCGTGCCCGGCATCGGCGAGGAGGCGCTCGCCATCCTGGAGCCCGGCCAGTATTTCGGT
GAGATGGCGGTCATCGAGGATTCGCCGCGCTCAGCGGACGCCATCGCCCACGTGAGCTGCTCCGTCTGGGTCATCGAGCG
CTCCCGGCTGGACCAGCTGATGTTCACCGACAAAGACCTGGCGTACGTGCTGCTCTGGACCTTCGTCCGCACGCTGAGCG
AACGGCTCCGCGAGACGAACGAGAAGATCAAGGGCTTCTTCGCCCTCTCCCGCTTCTGA

Upstream 100 bases:

>100_bases
TCACCTTGTTGATCTTCTCCTCCGCCACGACTCCTCCCAAATCTCGTTGATGGCCCCAAGGTACCAGAGCGCCTCGGGCG
CGTGATACGAAGCTGGCCTC

Downstream 100 bases:

>100_bases
CGGTCCGTCTCAGCACCCGAGAAGCCACCTGGTGCAGGGATGTCCGTCCGGCATCCGAGCCCCTTCCGACGTGTCGGGAC
GGGTACGCACCCCACTCCCC

Product: cyclic nucleotide-binding domain-containing protein

Products: NA

Alternate protein names: MlotiK1 channel [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MDAAVLKKVALFEGLTQGQLAKVAQIGHSRTYPAGAFLFREGETGQEMFVIAEGKVRISKSVPGIGEEALAILEPGQYFG
EMAVIEDSPRSADAIAHVSCSVWVIERSRLDQLMFTDKDLAYVLLWTFVRTLSERLRETNEKIKGFFALSRF

Sequences:

>Translated_152_residues
MDAAVLKKVALFEGLTQGQLAKVAQIGHSRTYPAGAFLFREGETGQEMFVIAEGKVRISKSVPGIGEEALAILEPGQYFG
EMAVIEDSPRSADAIAHVSCSVWVIERSRLDQLMFTDKDLAYVLLWTFVRTLSERLRETNEKIKGFFALSRF
>Mature_152_residues
MDAAVLKKVALFEGLTQGQLAKVAQIGHSRTYPAGAFLFREGETGQEMFVIAEGKVRISKSVPGIGEEALAILEPGQYFG
EMAVIEDSPRSADAIAHVSCSVWVIERSRLDQLMFTDKDLAYVLLWTFVRTLSERLRETNEKIKGFFALSRF

Specific function: Cyclic nucleotide-regulated potassium channel activated by cAMP [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cyclic nucleotide-binding domain [H]

Homologues:

Organism=Homo sapiens, GI5453978, Length=123, Percent_Identity=35.7723577235772, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI25144999, Length=109, Percent_Identity=32.1100917431193, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25145007, Length=109, Percent_Identity=32.1100917431193, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25145047, Length=111, Percent_Identity=29.7297297297297, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71989393, Length=111, Percent_Identity=29.7297297297297, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17539610, Length=111, Percent_Identity=29.7297297297297, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17539608, Length=111, Percent_Identity=29.7297297297297, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17137294, Length=93, Percent_Identity=38.7096774193548, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR018488
- InterPro:   IPR000595
- InterPro:   IPR013099
- InterPro:   IPR003091
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding; PF07885 Ion_trans_2 [H]

EC number: NA

Molecular weight: Translated: 16917; Mature: 16917

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAAVLKKVALFEGLTQGQLAKVAQIGHSRTYPAGAFLFREGETGQEMFVIAEGKVRISK
CCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEECCCEEEEC
SVPGIGEEALAILEPGQYFGEMAVIEDSPRSADAIAHVSCSVWVIERSRLDQLMFTDKDL
CCCCCCCHHEEEECCCHHHCCEEEEECCCCCCCCEEEEEEEEEEEEHHHHHHHHHCCCHH
AYVLLWTFVRTLSERLRETNEKIKGFFALSRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDAAVLKKVALFEGLTQGQLAKVAQIGHSRTYPAGAFLFREGETGQEMFVIAEGKVRISK
CCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEECCCEEEEC
SVPGIGEEALAILEPGQYFGEMAVIEDSPRSADAIAHVSCSVWVIERSRLDQLMFTDKDL
CCCCCCCHHEEEECCCHHHCCEEEEECCCCCCCCEEEEEEEEEEEEHHHHHHHHHCCCHH
AYVLLWTFVRTLSERLRETNEKIKGFFALSRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]