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The map label for this gene is ykoH [H]

Identifier: 108760911

GI number: 108760911

Start: 1360383

End: 1361813

Strand: Direct

Name: ykoH [H]

Synonym: MXAN_1166

Alternate gene names: 108760911

Gene position: 1360383-1361813 (Clockwise)

Preceding gene: 108758831

Following gene: 108761633

Centisome position: 14.88

GC content: 71.98

Gene sequence:

>1431_bases
GTGGCGAGCTCCCGCATCCCCATCCGCGGCTACCGGGCCGGCTTCTTCTTCGTGGTCGTCCTGCTGTCCGCCGTCACTGC
TTTCACGTTGTGGACGGAAGTCCGCACGGGCAGCCAGGTGGACGGGTTGGTGCAGGAGGCGCTGGAGCGGGCCGGCTCCA
TTGGCCGCATCCGCGTGGACGCGCTGTCGCTGGAGGCCGCCATCGAGGCGCATGTCCGCGCCACGGGTGACGCCGAGCGC
CGCGCCGCGGACGCGGTGATGGAGCAGATCCTGGCGGACATCCGCGCCTCGTCGGAGGCGTACACCCGCAACCTCCCGCA
GGGCGAGAAGGCGCTGTGGTACCGCTTCAACGCCGCGTGCCAGGGGCTGGCGGACCAGGTGCGCGCGGCGGCCATCTTCT
CGCAGCGCCGCGAGGCGGAGCGGGCCCGGCGCCACCTGGCCGAGCGCATCCGCCCGTTGGCGGCGGAGCTGGACGCGCTG
GGCGGCGCGCTGGAGGAGGAGAATGCGGCCGAGGCACGCAGGCTGGTGAACCGGTTGGAGGACCTGCGCGTGCGCAACAC
CGCCCTGGGCGCGGGTGCCACGCTGCTGGCCATCCTCCTGTCGTCGCTGGTGGGCTGGCGCGTCACCTCGCTGCTCAAGC
GCCAGGAGGCCATCATCCAAGGGCAGTTGGAGGAGCTGGGCCGGCACAACCAGGAACTGGACGCCTTCACTCGGCGCGTG
GCGCACGACCTCATCTCCCCGCTGGCGCCGCTCAAGGGCTACCTGACGCTCATCCGCCGCACCGGCGCGGTGAACGACGC
GGGCGCGCTGGAGATGCTGGCGCAGTGTGAGTCCAGCGCTGTTCGCATGGGCGAGCTCATCGAGGCGCTGCTGCGCTTCT
GCCGCGCCGGTACGCGCGGCGAGAGTACGGTGGGTGAGCTGGACACGGCCGTCACCACCGTGTTGCTGGAGGTGGCGCAG
ACGGCGGCGGCGCAGGGCGTGGCGCTGGAGCGGGAGCTGGAGCCCGGCGTGGCGGTGGACTGCCCCGGACAGTTGTTGCA
GGTGAGTGCGCGCAACCTGCTCACCAACGCGGTGAAGTACTCGGCGGGCCGGCCCGACCCCCGGGTGAAGGTGCGCGTGG
CCACCGAGGACGGCATGGCCGTGCTGGAGGTCGTGGACAACGGCATCGGCATGGCGCCGGGCACCCAGGCCTCACTGTTC
CAGCCCTTCTTCCGCGCGCCTGAGGTGCGCGGGCTGCCGGGCCACGGACTGGGGCTGGTCACCACCAAGCGCGTGGTGGA
GGCGCACGGCGGCACGCTGGTGGTGCGCTCGGAAGAAGGAAAGGGAACGCACGTGGTGGTGCGCTTCCCCCGCGTGGTGC
GCCCGGCGGCGGGCACCAGCGGTTCTCAGACAACGACTGCTTCCGCCGGAATGCGCAAGGTCGGAACATGA

Upstream 100 bases:

>100_bases
GCCCCAGCCGGCTGCCCCCCCGGCGGCCGGGAACGTCGCCCCGACGGCGCCCTGAAGTCCCGCCGGACGCGCGGCGCTGG
CCCCGTGATAGAGGAACGGC

Downstream 100 bases:

>100_bases
GCTCAGCCCGCATCCTCGTCGTGGATGATGACCCGCAGGCCCGCGATTTGCTCCAGCGCTTGCTGGGGCCGCTGGGGGCG
GTGACGCAGGCTCCGGACCC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MASSRIPIRGYRAGFFFVVVLLSAVTAFTLWTEVRTGSQVDGLVQEALERAGSIGRIRVDALSLEAAIEAHVRATGDAER
RAADAVMEQILADIRASSEAYTRNLPQGEKALWYRFNAACQGLADQVRAAAIFSQRREAERARRHLAERIRPLAAELDAL
GGALEEENAAEARRLVNRLEDLRVRNTALGAGATLLAILLSSLVGWRVTSLLKRQEAIIQGQLEELGRHNQELDAFTRRV
AHDLISPLAPLKGYLTLIRRTGAVNDAGALEMLAQCESSAVRMGELIEALLRFCRAGTRGESTVGELDTAVTTVLLEVAQ
TAAAQGVALERELEPGVAVDCPGQLLQVSARNLLTNAVKYSAGRPDPRVKVRVATEDGMAVLEVVDNGIGMAPGTQASLF
QPFFRAPEVRGLPGHGLGLVTTKRVVEAHGGTLVVRSEEGKGTHVVVRFPRVVRPAAGTSGSQTTTASAGMRKVGT

Sequences:

>Translated_476_residues
MASSRIPIRGYRAGFFFVVVLLSAVTAFTLWTEVRTGSQVDGLVQEALERAGSIGRIRVDALSLEAAIEAHVRATGDAER
RAADAVMEQILADIRASSEAYTRNLPQGEKALWYRFNAACQGLADQVRAAAIFSQRREAERARRHLAERIRPLAAELDAL
GGALEEENAAEARRLVNRLEDLRVRNTALGAGATLLAILLSSLVGWRVTSLLKRQEAIIQGQLEELGRHNQELDAFTRRV
AHDLISPLAPLKGYLTLIRRTGAVNDAGALEMLAQCESSAVRMGELIEALLRFCRAGTRGESTVGELDTAVTTVLLEVAQ
TAAAQGVALERELEPGVAVDCPGQLLQVSARNLLTNAVKYSAGRPDPRVKVRVATEDGMAVLEVVDNGIGMAPGTQASLF
QPFFRAPEVRGLPGHGLGLVTTKRVVEAHGGTLVVRSEEGKGTHVVVRFPRVVRPAAGTSGSQTTTASAGMRKVGT
>Mature_475_residues
ASSRIPIRGYRAGFFFVVVLLSAVTAFTLWTEVRTGSQVDGLVQEALERAGSIGRIRVDALSLEAAIEAHVRATGDAERR
AADAVMEQILADIRASSEAYTRNLPQGEKALWYRFNAACQGLADQVRAAAIFSQRREAERARRHLAERIRPLAAELDALG
GALEEENAAEARRLVNRLEDLRVRNTALGAGATLLAILLSSLVGWRVTSLLKRQEAIIQGQLEELGRHNQELDAFTRRVA
HDLISPLAPLKGYLTLIRRTGAVNDAGALEMLAQCESSAVRMGELIEALLRFCRAGTRGESTVGELDTAVTTVLLEVAQT
AAAQGVALERELEPGVAVDCPGQLLQVSARNLLTNAVKYSAGRPDPRVKVRVATEDGMAVLEVVDNGIGMAPGTQASLFQ
PFFRAPEVRGLPGHGLGLVTTKRVVEAHGGTLVVRSEEGKGTHVVVRFPRVVRPAAGTSGSQTTTASAGMRKVGT

Specific function: Probable member of the two-component regulatory system ykoH/ykoG. Potentially phosphorylates ykoG [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789808, Length=222, Percent_Identity=27.4774774774775, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788549, Length=233, Percent_Identity=29.1845493562232, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786912, Length=224, Percent_Identity=26.3392857142857, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=30.0925925925926, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=29.1479820627803, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790551, Length=245, Percent_Identity=28.1632653061224, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI48994928, Length=230, Percent_Identity=26.5217391304348, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51025; Mature: 50894

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSRIPIRGYRAGFFFVVVLLSAVTAFTLWTEVRTGSQVDGLVQEALERAGSIGRIRVD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEH
ALSLEAAIEAHVRATGDAERRAADAVMEQILADIRASSEAYTRNLPQGEKALWYRFNAAC
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHH
QGLADQVRAAAIFSQRREAERARRHLAERIRPLAAELDALGGALEEENAAEARRLVNRLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
DLRVRNTALGAGATLLAILLSSLVGWRVTSLLKRQEAIIQGQLEELGRHNQELDAFTRRV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AHDLISPLAPLKGYLTLIRRTGAVNDAGALEMLAQCESSAVRMGELIEALLRFCRAGTRG
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ESTVGELDTAVTTVLLEVAQTAAAQGVALERELEPGVAVDCPGQLLQVSARNLLTNAVKY
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHCCCCCEECCCHHHHHHHHHHHHHHHHHH
SAGRPDPRVKVRVATEDGMAVLEVVDNGIGMAPGTQASLFQPFFRAPEVRGLPGHGLGLV
CCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHH
TTKRVVEAHGGTLVVRSEEGKGTHVVVRFPRVVRPAAGTSGSQTTTASAGMRKVGT
HHHHHHHHCCCEEEEECCCCCCCEEEEECCHHHCCCCCCCCCCCCCHHHCHHHCCC
>Mature Secondary Structure 
ASSRIPIRGYRAGFFFVVVLLSAVTAFTLWTEVRTGSQVDGLVQEALERAGSIGRIRVD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEH
ALSLEAAIEAHVRATGDAERRAADAVMEQILADIRASSEAYTRNLPQGEKALWYRFNAAC
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHH
QGLADQVRAAAIFSQRREAERARRHLAERIRPLAAELDALGGALEEENAAEARRLVNRLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
DLRVRNTALGAGATLLAILLSSLVGWRVTSLLKRQEAIIQGQLEELGRHNQELDAFTRRV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AHDLISPLAPLKGYLTLIRRTGAVNDAGALEMLAQCESSAVRMGELIEALLRFCRAGTRG
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ESTVGELDTAVTTVLLEVAQTAAAQGVALERELEPGVAVDCPGQLLQVSARNLLTNAVKY
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHCCCCCEECCCHHHHHHHHHHHHHHHHHH
SAGRPDPRVKVRVATEDGMAVLEVVDNGIGMAPGTQASLFQPFFRAPEVRGLPGHGLGLV
CCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHH
TTKRVVEAHGGTLVVRSEEGKGTHVVVRFPRVVRPAAGTSGSQTTTASAGMRKVGT
HHHHHHHHCCCEEEEECCCCCCCEEEEECCHHHCCCCCCCCCCCCCHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]