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The map label for this gene is dck [H]

Identifier: 108760699

GI number: 108760699

Start: 3014265

End: 3014906

Strand: Reverse

Name: dck [H]

Synonym: MXAN_2591

Alternate gene names: 108760699

Gene position: 3014906-3014265 (Counterclockwise)

Preceding gene: 108759970

Following gene: 108762715

Centisome position: 32.99

GC content: 64.49

Gene sequence:

>642_bases
ATGCGTGTCAAGGTGCCCAAGGCGCGGCGCTTCGTGGCGCTGGCGGGCAACATCGGCGCGGGCAAGACGACGGCGGCGAA
GATGATCAGCCAGGCCTTCGGCTACGAGCTGTTCGACGAGCCCGTTATCGACAACCGCTTCCTGCGTGACTACTACGCGG
ACATGACGCGGTGGTCCTTCACGCTCCAGCTCGAGTTCCTCATCCGGCGCGTCGAACACCACGAGCTCATCCATTCGTAC
CGCCGCAGCTGCGTGCAGGACCGCACCCTGTACGAGGACCCGGAAATCTTCGCCAAGTACCTCCATGGCCTGGGGCACCT
GACGAACGCGGAGCTGGACCTGTACTACGAGTACTTCCAGCGGCTGTCGCGCCACATCATCCGGCCCGACAAGGTCATCT
GCTTCGAGGTCGGCAGCGTGGAGGTGCTCCTCCAGCGCATCCGCACCCGGGGACGCGAGGAGGAGAAGGGCATCCGCCAC
CAGTTCCTTCGGGGCCTCAACGGCTACTACGCCAGCTTCCCCCTGGTGATACAGGAGAAGTACGGCGTGGACTGCCTCAC
CATGGACGTGTCGAAGCAGGACATCCGGCGAGGCCGGGGACGTGAGGAGTTCCTCGACCGCGTCTCCACCTTCCTGTCCT
GA

Upstream 100 bases:

>100_bases
ATTCATGCCTCGCACCACCGCTCGCACGCGCTCGAAGCCCGCCCAGGCCGCCCCCGCCCAGGAAAAGGCCCCCGCGGCCC
CCCCGCGTTCCCGCAACACG

Downstream 100 bases:

>100_bases
GCGCCGCGCCCGCGCCTGTCACCTGCGCGGACATTGTCTGGCCCATCGCGTTAGATTCTGGGATATCCACCGGATGAACC
GGCGCGGCCCGGCCGCAGGC

Product: deoxynucleoside kinase family protein

Products: NA

Alternate protein names: dAK/dCK [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MRVKVPKARRFVALAGNIGAGKTTAAKMISQAFGYELFDEPVIDNRFLRDYYADMTRWSFTLQLEFLIRRVEHHELIHSY
RRSCVQDRTLYEDPEIFAKYLHGLGHLTNAELDLYYEYFQRLSRHIIRPDKVICFEVGSVEVLLQRIRTRGREEEKGIRH
QFLRGLNGYYASFPLVIQEKYGVDCLTMDVSKQDIRRGRGREEFLDRVSTFLS

Sequences:

>Translated_213_residues
MRVKVPKARRFVALAGNIGAGKTTAAKMISQAFGYELFDEPVIDNRFLRDYYADMTRWSFTLQLEFLIRRVEHHELIHSY
RRSCVQDRTLYEDPEIFAKYLHGLGHLTNAELDLYYEYFQRLSRHIIRPDKVICFEVGSVEVLLQRIRTRGREEEKGIRH
QFLRGLNGYYASFPLVIQEKYGVDCLTMDVSKQDIRRGRGREEFLDRVSTFLS
>Mature_213_residues
MRVKVPKARRFVALAGNIGAGKTTAAKMISQAFGYELFDEPVIDNRFLRDYYADMTRWSFTLQLEFLIRRVEHHELIHSY
RRSCVQDRTLYEDPEIFAKYLHGLGHLTNAELDLYYEYFQRLSRHIIRPDKVICFEVGSVEVLLQRIRTRGREEEKGIRH
QFLRGLNGYYASFPLVIQEKYGVDCLTMDVSKQDIRRGRGREEFLDRVSTFLS

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dATP AND dCTP for DNA metabolism. The phosphate acceptor specificity is strict toward deoxyadenosine (dAdo) and deoxycytidine (dCyd). The specificity toward the sugar moiety of the n

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

Organism=Homo sapiens, GI18426967, Length=242, Percent_Identity=23.9669421487603, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.74; =2.7.1.76 [H]

Molecular weight: Translated: 25181; Mature: 25181

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVKVPKARRFVALAGNIGAGKTTAAKMISQAFGYELFDEPVIDNRFLRDYYADMTRWSF
CCCCCCCHHHEEEEECCCCCCHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHH
TLQLEFLIRRVEHHELIHSYRRSCVQDRTLYEDPEIFAKYLHGLGHLTNAELDLYYEYFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
RLSRHIIRPDKVICFEVGSVEVLLQRIRTRGREEEKGIRHQFLRGLNGYYASFPLVIQEK
HHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCEEEECC
YGVDCLTMDVSKQDIRRGRGREEFLDRVSTFLS
CCCEEEEECCCHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRVKVPKARRFVALAGNIGAGKTTAAKMISQAFGYELFDEPVIDNRFLRDYYADMTRWSF
CCCCCCCHHHEEEEECCCCCCHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHH
TLQLEFLIRRVEHHELIHSYRRSCVQDRTLYEDPEIFAKYLHGLGHLTNAELDLYYEYFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
RLSRHIIRPDKVICFEVGSVEVLLQRIRTRGREEEKGIRHQFLRGLNGYYASFPLVIQEK
HHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCEEEECC
YGVDCLTMDVSKQDIRRGRGREEFLDRVSTFLS
CCCEEEEECCCHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]