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The map label for this gene is lspA [H]

Identifier: 108760550

GI number: 108760550

Start: 4804061

End: 4804576

Strand: Reverse

Name: lspA [H]

Synonym: MXAN_3944

Alternate gene names: 108760550

Gene position: 4804576-4804061 (Counterclockwise)

Preceding gene: 108763558

Following gene: 108757259

Centisome position: 52.57

GC content: 62.21

Gene sequence:

>516_bases
ATGAACACTCCTTCCTTGACGAACTGGCCTGCCCGCCTGGGCTATCTCCTTGCCGTTGGCGGCGCATGGTTCGCGGCCGA
TCAAGTCACCAAACAGATGGCGCGCGACGGGGCGAAAAGGCCCGTCGCGGTCTTCGATAGCTGGTGGCACTTCCACTACG
TGGAGAACCGAGCGGGTGCGTTCGGTCTGTTCTCCAGCTTCGGCGAAGAGTGGCGCATGCCTTTCTTCTACGTCGTGGGC
GCCATCTGCATCGTGTTGCTGATTGGCTACTACTTCTACACGCCGCCGACGATGAAGCTCCAGCGCTGGTCGCTGGCGAC
GATGATTGGCGGCGCGTTGGGCAACTACGTGGACCGGGTGCGCCTGCGCTACGTGGTGGATTTCGTGTCATGGCACGTGG
GGGACCGCTTCTATTGGCCCTCCTTCAACATCGCGGACACAGCGGTAGTCGTAGGGGCCGCCCTGATGATCCTGGAGTCG
TTCCGCGAGCCGCGTCAGCAGTTGTCTCCCGGATAG

Upstream 100 bases:

>100_bases
GACGGCGAGCCGCCCGCGCATGCTCGCCTTGCGAAGGGTCGTGGACTATCATCGTCAGTACGAGTGGGTGTAGCTCATAC
GCCACCTCCAATTCCGACGA

Downstream 100 bases:

>100_bases
GCCCCGCCATGGGTGTGCGGTCGGCCGCCGGGCCAAGGACTGGAGTTCATGGGGACCTCAGAGCCAGTTGAGCCGGACCA
CGCCTTGTCAAAACCACCGC

Product: signal peptidase II

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MNTPSLTNWPARLGYLLAVGGAWFAADQVTKQMARDGAKRPVAVFDSWWHFHYVENRAGAFGLFSSFGEEWRMPFFYVVG
AICIVLLIGYYFYTPPTMKLQRWSLATMIGGALGNYVDRVRLRYVVDFVSWHVGDRFYWPSFNIADTAVVVGAALMILES
FREPRQQLSPG

Sequences:

>Translated_171_residues
MNTPSLTNWPARLGYLLAVGGAWFAADQVTKQMARDGAKRPVAVFDSWWHFHYVENRAGAFGLFSSFGEEWRMPFFYVVG
AICIVLLIGYYFYTPPTMKLQRWSLATMIGGALGNYVDRVRLRYVVDFVSWHVGDRFYWPSFNIADTAVVVGAALMILES
FREPRQQLSPG
>Mature_171_residues
MNTPSLTNWPARLGYLLAVGGAWFAADQVTKQMARDGAKRPVAVFDSWWHFHYVENRAGAFGLFSSFGEEWRMPFFYVVG
AICIVLLIGYYFYTPPTMKLQRWSLATMIGGALGNYVDRVRLRYVVDFVSWHVGDRFYWPSFNIADTAVVVGAALMILES
FREPRQQLSPG

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=118, Percent_Identity=38.135593220339, Blast_Score=77, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 19491; Mature: 19491

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPSLTNWPARLGYLLAVGGAWFAADQVTKQMARDGAKRPVAVFDSWWHFHYVENRAGA
CCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCH
FGLFSSFGEEWRMPFFYVVGAICIVLLIGYYFYTPPTMKLQRWSLATMIGGALGNYVDRV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RLRYVVDFVSWHVGDRFYWPSFNIADTAVVVGAALMILESFREPRQQLSPG
HHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNTPSLTNWPARLGYLLAVGGAWFAADQVTKQMARDGAKRPVAVFDSWWHFHYVENRAGA
CCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCH
FGLFSSFGEEWRMPFFYVVGAICIVLLIGYYFYTPPTMKLQRWSLATMIGGALGNYVDRV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RLRYVVDFVSWHVGDRFYWPSFNIADTAVVVGAALMILESFREPRQQLSPG
HHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]