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The map label for this gene is ptp [H]

Identifier: 108760218

GI number: 108760218

Start: 2602994

End: 2604979

Strand: Reverse

Name: ptp [H]

Synonym: MXAN_2253

Alternate gene names: 108760218

Gene position: 2604979-2602994 (Counterclockwise)

Preceding gene: 108758216

Following gene: 108761658

Centisome position: 28.5

GC content: 68.88

Gene sequence:

>1986_bases
ATGCGCTACAGTCTCGCAGCCAAGGCATCTGCGACACCGCGTCCATCAACTGAGGGGTTCATGCTCCGTTCAAGAAGGTT
GTCTCACTCCATCCTGCTGCTACTTCCGCTGCTGCTGGCCTTGACACAGACGGCCTGCGGCGGCGACACGCCCGAGCCCC
GCCAGGATGCAGGCATCCAGACGCCCGACGCAGGCAGGGACGATGCGGGCACCGATGACGCGGGCACCGATGACGCAGGT
ACGGACGACGCGGGCACCGAGCCGGACGACGCGGGCACCGACGACGCGGGCACGGAGCCGGACGACGCAGGCACCGACGA
CGCGGGCACGGAGCCGGACGACGCAGGCACCGACGACGCGGGCACGGAGCCGGACGACGCAGGCACCGACGACGCGGGCA
CGGAGCCGGACGACGCAGGCACCGACGACGCGGGCACGGAGCCGGACGACGCGGGCACCGATGACGCGGGCACGGAGCCG
GACGACGCGGGCACCGATGACGCGGGCACGGGTGAGGAGGACGGAGGCTCGGGCCCGACGGACGGGGGCACCGGAGACGG
GGGCACGGAACCACAGGAGTGCCCGTTCGGGCCGCCGGATGGCGGTGTCTCGAACCCGGGCGACCCGACTGTCATCCAGG
ACCCGACCGCGGACATCCTGGACCGGCTGCGGGCCATTCCCGGCCTCACCGTCGCGGAGAACCCCAACGGCGTCACGGTC
CCCGCGGGTCACCGCTTCTTTGTCATGGAGTACGACCAGCCCGCCGACCACGCACGCCCCGAGTGCCAGCGATTCAAGCA
GCGATTGGTCCTTCTGCACCGTTCGGTCACGGCGCCCATGGTCTTCTACGCGAGCGGCTACTACGTGTCCCTGAACGCGG
GCCGTCGCGAGCTGACGACGTTGCTGGCCGCGAATCAGCTCTCCATCGAGCACCGCTTCTTCCTGCCCAGCCGTCCGGAG
CCCGCTGACTGGAGCCAGCTCACCATCAAGCAGTCAGCGGACGACTTCCACCGGGTCGCTCAGGCAATCAAGCAAATCTA
TTCCGCGTCCTGGGTGTCCACGGGCGTCAGCAAGGGCGGAGAGACCATGGTGTTCTACCGCCGGTTCCACCCGGAGGACG
TGGACGCGACGGTGGCCTATGTGGCGCCGCTCGTGCGCGGCGAAGATGAGCGTTTCCCCGCCTTCCAAGCCACCGTGGGA
GGTCCGCAGCTGGAGGGGTGCCGCGAGCAAATCCACACCTTCCAGCGCGCCGTACTGAACCGCCGCCAGGAGATGGTGGC
GCTGCTGCGCGCCTATGCCGTGAACCAGGGCCTCACCTACAACCACCTTGGCTTCGAGCGGGCCCTGGAGCACGCCGTCA
TCGAGACGTACTTCGCCTTCTGGCAGTACTCCCTCCCCCAGTACTGCGACGCGTTCCCGGATGACACGGCGTCGCCTGAG
TACATGCTGGACATCATTGACTGGGCGGTGGGCCTTGAAGCGTTCTCCGACAACAGCAGCTCCGGCATTGCCGCGTACTA
CCCCTACTACTACCAGGCGAGTCTGGAGCTGGGCTGGCCCAAGCCCTACGAGGCGCACCTGGGCAGCCTCATCCAGTACC
CCGGGACGAACATCGCGCCGGTGTACTCGACGCCCGGCGTGCCGGTCGTGTTCCGGCCCCAGGCCATGCAGGACATCGAG
GACTGGCTCGTGACGCATGGCGAGCGGGTGATGTTCATCTATGGCGACCTGGACCCGTGGACCGCGGCGGCGTTCCCGCT
CGGCAACGCCCAGGACTCCTTCGTGTTCACGGCTCCGGGCGGCAACCACGGAAGCACCTTCAACTGGCTTCCCACCACCC
TTCGGGACCAGGCCCAGGACATCGTGCGGCGCTGGGCAGGCGTCCCGTCACTGAAGCACGCCCCGGTGCCGCTCCCGGAG
GCCGACACCGTCGAGTTCGGCCCACACCTGCCGCCCCGGCGGCTGCAACCGCCCCCGGCCCCGTAA

Upstream 100 bases:

>100_bases
CCCATCGAACGTGAAGGCAGACAGCGCTCCGGCTGGAATCCTCCAGCGGCGCGCGGGGACTGGCACCCGCACCACAACGG
GGCACGGCGACGGCAGACCG

Downstream 100 bases:

>100_bases
CCCGCGGCGAACGCCGCTCACCGGAGAAGCCGTTCCGGTGAGCGGCTGAATCCATCCAAGCCACCCACGGCCGCGGCCCC
GTATCAAGCCGTATCGTGGG

Product: S37 family peptidase

Products: NA

Alternate protein names: PTP-SM; Tripeptidyl aminopeptidase; SM-TAP [H]

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MRYSLAAKASATPRPSTEGFMLRSRRLSHSILLLLPLLLALTQTACGGDTPEPRQDAGIQTPDAGRDDAGTDDAGTDDAG
TDDAGTEPDDAGTDDAGTEPDDAGTDDAGTEPDDAGTDDAGTEPDDAGTDDAGTEPDDAGTDDAGTEPDDAGTDDAGTEP
DDAGTDDAGTGEEDGGSGPTDGGTGDGGTEPQECPFGPPDGGVSNPGDPTVIQDPTADILDRLRAIPGLTVAENPNGVTV
PAGHRFFVMEYDQPADHARPECQRFKQRLVLLHRSVTAPMVFYASGYYVSLNAGRRELTTLLAANQLSIEHRFFLPSRPE
PADWSQLTIKQSADDFHRVAQAIKQIYSASWVSTGVSKGGETMVFYRRFHPEDVDATVAYVAPLVRGEDERFPAFQATVG
GPQLEGCREQIHTFQRAVLNRRQEMVALLRAYAVNQGLTYNHLGFERALEHAVIETYFAFWQYSLPQYCDAFPDDTASPE
YMLDIIDWAVGLEAFSDNSSSGIAAYYPYYYQASLELGWPKPYEAHLGSLIQYPGTNIAPVYSTPGVPVVFRPQAMQDIE
DWLVTHGERVMFIYGDLDPWTAAAFPLGNAQDSFVFTAPGGNHGSTFNWLPTTLRDQAQDIVRRWAGVPSLKHAPVPLPE
ADTVEFGPHLPPRRLQPPPAP

Sequences:

>Translated_661_residues
MRYSLAAKASATPRPSTEGFMLRSRRLSHSILLLLPLLLALTQTACGGDTPEPRQDAGIQTPDAGRDDAGTDDAGTDDAG
TDDAGTEPDDAGTDDAGTEPDDAGTDDAGTEPDDAGTDDAGTEPDDAGTDDAGTEPDDAGTDDAGTEPDDAGTDDAGTEP
DDAGTDDAGTGEEDGGSGPTDGGTGDGGTEPQECPFGPPDGGVSNPGDPTVIQDPTADILDRLRAIPGLTVAENPNGVTV
PAGHRFFVMEYDQPADHARPECQRFKQRLVLLHRSVTAPMVFYASGYYVSLNAGRRELTTLLAANQLSIEHRFFLPSRPE
PADWSQLTIKQSADDFHRVAQAIKQIYSASWVSTGVSKGGETMVFYRRFHPEDVDATVAYVAPLVRGEDERFPAFQATVG
GPQLEGCREQIHTFQRAVLNRRQEMVALLRAYAVNQGLTYNHLGFERALEHAVIETYFAFWQYSLPQYCDAFPDDTASPE
YMLDIIDWAVGLEAFSDNSSSGIAAYYPYYYQASLELGWPKPYEAHLGSLIQYPGTNIAPVYSTPGVPVVFRPQAMQDIE
DWLVTHGERVMFIYGDLDPWTAAAFPLGNAQDSFVFTAPGGNHGSTFNWLPTTLRDQAQDIVRRWAGVPSLKHAPVPLPE
ADTVEFGPHLPPRRLQPPPAP
>Mature_661_residues
MRYSLAAKASATPRPSTEGFMLRSRRLSHSILLLLPLLLALTQTACGGDTPEPRQDAGIQTPDAGRDDAGTDDAGTDDAG
TDDAGTEPDDAGTDDAGTEPDDAGTDDAGTEPDDAGTDDAGTEPDDAGTDDAGTEPDDAGTDDAGTEPDDAGTDDAGTEP
DDAGTDDAGTGEEDGGSGPTDGGTGDGGTEPQECPFGPPDGGVSNPGDPTVIQDPTADILDRLRAIPGLTVAENPNGVTV
PAGHRFFVMEYDQPADHARPECQRFKQRLVLLHRSVTAPMVFYASGYYVSLNAGRRELTTLLAANQLSIEHRFFLPSRPE
PADWSQLTIKQSADDFHRVAQAIKQIYSASWVSTGVSKGGETMVFYRRFHPEDVDATVAYVAPLVRGEDERFPAFQATVG
GPQLEGCREQIHTFQRAVLNRRQEMVALLRAYAVNQGLTYNHLGFERALEHAVIETYFAFWQYSLPQYCDAFPDDTASPE
YMLDIIDWAVGLEAFSDNSSSGIAAYYPYYYQASLELGWPKPYEAHLGSLIQYPGTNIAPVYSTPGVPVVFRPQAMQDIE
DWLVTHGERVMFIYGDLDPWTAAAFPLGNAQDSFVFTAPGGNHGSTFNWLPTTLRDQAQDIVRRWAGVPSLKHAPVPLPE
ADTVEFGPHLPPRRLQPPPAP

Specific function: Has proline-specific tripeptidyl aminopeptidase and tetrapeptidyl aminopeptidase activity. Activity is highest against tripeptides containing an Ala-Pro motif. Involved in the final processing of transglutaminase, by removing either the tetrapeptide Phe-A

COG id: COG5271

COG function: function code R; AAA ATPase containing von Willebrand factor type A (vWA) domain

Gene ontology:

Cell location: Secreted. Cell surface. Note=Secreted (PubMed:14519127). Cell surface (PubMed:15598885) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S37 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008761 [H]

Pfam domain/function: PF05576 Peptidase_S37 [H]

EC number: NA

Molecular weight: Translated: 71211; Mature: 71211

Theoretical pI: Translated: 4.06; Mature: 4.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYSLAAKASATPRPSTEGFMLRSRRLSHSILLLLPLLLALTQTACGGDTPEPRQDAGIQ
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCC
TPDAGRDDAGTDDAGTDDAGTDDAGTEPDDAGTDDAGTEPDDAGTDDAGTEPDDAGTDDA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GTEPDDAGTDDAGTEPDDAGTDDAGTEPDDAGTDDAGTEPDDAGTDDAGTGEEDGGSGPT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DGGTGDGGTEPQECPFGPPDGGVSNPGDPTVIQDPTADILDRLRAIPGLTVAENPNGVTV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHCCCCEEECCCCCEEE
PAGHRFFVMEYDQPADHARPECQRFKQRLVLLHRSVTAPMVFYASGYYVSLNAGRRELTT
CCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEECCCHHHHHH
LLAANQLSIEHRFFLPSRPEPADWSQLTIKQSADDFHRVAQAIKQIYSASWVSTGVSKGG
HHHHHHHCCEEEEECCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ETMVFYRRFHPEDVDATVAYVAPLVRGEDERFPAFQATVGGPQLEGCREQIHTFQRAVLN
CEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHH
RRQEMVALLRAYAVNQGLTYNHLGFERALEHAVIETYFAFWQYSLPQYCDAFPDDTASPE
HHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHH
YMLDIIDWAVGLEAFSDNSSSGIAAYYPYYYQASLELGWPKPYEAHLGSLIQYPGTNIAP
HHHHHHHHHHHHHHHCCCCCCCEEEECCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCEE
VYSTPGVPVVFRPQAMQDIEDWLVTHGERVMFIYGDLDPWTAAAFPLGNAQDSFVFTAPG
EECCCCCCEEECCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHCCCCCCCCCEEEECCC
GNHGSTFNWLPTTLRDQAQDIVRRWAGVPSLKHAPVPLPEADTVEFGPHLPPRRLQPPPA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
P
C
>Mature Secondary Structure
MRYSLAAKASATPRPSTEGFMLRSRRLSHSILLLLPLLLALTQTACGGDTPEPRQDAGIQ
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCC
TPDAGRDDAGTDDAGTDDAGTDDAGTEPDDAGTDDAGTEPDDAGTDDAGTEPDDAGTDDA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GTEPDDAGTDDAGTEPDDAGTDDAGTEPDDAGTDDAGTEPDDAGTDDAGTGEEDGGSGPT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DGGTGDGGTEPQECPFGPPDGGVSNPGDPTVIQDPTADILDRLRAIPGLTVAENPNGVTV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHCCCCEEECCCCCEEE
PAGHRFFVMEYDQPADHARPECQRFKQRLVLLHRSVTAPMVFYASGYYVSLNAGRRELTT
CCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEECCCHHHHHH
LLAANQLSIEHRFFLPSRPEPADWSQLTIKQSADDFHRVAQAIKQIYSASWVSTGVSKGG
HHHHHHHCCEEEEECCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ETMVFYRRFHPEDVDATVAYVAPLVRGEDERFPAFQATVGGPQLEGCREQIHTFQRAVLN
CEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHH
RRQEMVALLRAYAVNQGLTYNHLGFERALEHAVIETYFAFWQYSLPQYCDAFPDDTASPE
HHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHH
YMLDIIDWAVGLEAFSDNSSSGIAAYYPYYYQASLELGWPKPYEAHLGSLIQYPGTNIAP
HHHHHHHHHHHHHHHCCCCCCCEEEECCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCEE
VYSTPGVPVVFRPQAMQDIEDWLVTHGERVMFIYGDLDPWTAAAFPLGNAQDSFVFTAPG
EECCCCCCEEECCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHCCCCCCCCCEEEECCC
GNHGSTFNWLPTTLRDQAQDIVRRWAGVPSLKHAPVPLPEADTVEFGPHLPPRRLQPPPA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA