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The map label for this gene is 108761658

Identifier: 108761658

GI number: 108761658

Start: 2601650

End: 2602675

Strand: Reverse

Name: 108761658

Synonym: MXAN_2252

Alternate gene names: NA

Gene position: 2602675-2601650 (Counterclockwise)

Preceding gene: 108760218

Following gene: 108757510

Centisome position: 28.48

GC content: 68.23

Gene sequence:

>1026_bases
ATGCTGCTCCACAAGCACCTCACCCCCGAGCTGAAATCCCGGCTCGAACGGCTCACGACACGCAACGGCTGGACGCTCCG
GAAGACCATCCAGAGTGGCCTGGACCACGGAGACTCCCAGATGGGTGTCTACGCGGGTGACAGCGAGTCCTACGCGCTCT
TCTCCCCGCTGCTGCATCCCATCATCCGGGACCATTCGGGCCATGACCTGAGCGGACACACGAGTGACTTCTCACTCGAC
GGGCTGCCCCAGGGCGACCTGGACCCCACGGGCGAGTTCATCCTCTCCACGCGGGTCCGCGTCGGACGGAACCTGGCCCG
GTATGCCTTTCCTCCGGCCATTGGCGCCAGGGACAGGGCCGCGCTGGAAGCCGAGGTCGTCCAGGTCCTCTCCGGCCTGA
GGGGCCACCTCGCGGGCAAATACCATCCCCTGGCCAGCCTCTCCGAGGCGGAGCGGCTGGAGCTGGTGCACCACCACGTC
CTGTTCCAGCAGTCGGACCGCTTCCTGGACAGCGCGGGCGTCAACCGCGACTGGCCTCGCAACCGCGGCATCTTCCACTC
CGCGGACATGCGCTTCATCGTCTGGGTCGGGGAGGAAGACGCCCTGCGCATCATCAGCATGCAGCCCGGCTCGGGGCTGG
CGCAGACCTACCTCCGGCTCCAGACGGCGCTCGAGCAGTTCGACGGGCAGCTCGACTTCGCCCAGGACTCACGGCTGGGC
TTCCTCACGGCGTGCCCCACCAACCTGGGCACCGCCATGCGAGCCTCCGTCCTCATCCGCCTGCCCCACTTGTCACGGCG
GCCGGACTTCCGCGCGCGGTGTGCCCGCCTGGGGCTCGCGGTGCGGGGGCTGCACGGCGAACACTCCGAAGCCCGGGACG
GCATCCATGATGTCTCCAATGCCACCCGTCTGGGCGTCACCGAGCGGGACATCTACGAACAGCTTCGGACGGGCATCCAC
GCGCTCATGGAGATGGAATCCGCGGCACGAAAGCGCGGACACCCGAAGGTGGCGCCCGGGAACTGA

Upstream 100 bases:

>100_bases
GCGCCGCGTGATACACGGCAGCTCGCTCGCCAAACATCGAAAATCACATACATTTGAGCAGCAACAACCGTGGCATATAT
CGTGCTCAAGCCACGGAGCG

Downstream 100 bases:

>100_bases
AAGCCCCCGGAGCGCCTCGCATCGCGCTCAGGACTTGGGAATCCAGCCATCCACGAGCGCCTGGTTCTTCTTCACCCACT
CCCGGGTGGCCTTCTCCGGC

Product: putative arginine kinase

Products: ADP; phosphocreatine

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MLLHKHLTPELKSRLERLTTRNGWTLRKTIQSGLDHGDSQMGVYAGDSESYALFSPLLHPIIRDHSGHDLSGHTSDFSLD
GLPQGDLDPTGEFILSTRVRVGRNLARYAFPPAIGARDRAALEAEVVQVLSGLRGHLAGKYHPLASLSEAERLELVHHHV
LFQQSDRFLDSAGVNRDWPRNRGIFHSADMRFIVWVGEEDALRIISMQPGSGLAQTYLRLQTALEQFDGQLDFAQDSRLG
FLTACPTNLGTAMRASVLIRLPHLSRRPDFRARCARLGLAVRGLHGEHSEARDGIHDVSNATRLGVTERDIYEQLRTGIH
ALMEMESAARKRGHPKVAPGN

Sequences:

>Translated_341_residues
MLLHKHLTPELKSRLERLTTRNGWTLRKTIQSGLDHGDSQMGVYAGDSESYALFSPLLHPIIRDHSGHDLSGHTSDFSLD
GLPQGDLDPTGEFILSTRVRVGRNLARYAFPPAIGARDRAALEAEVVQVLSGLRGHLAGKYHPLASLSEAERLELVHHHV
LFQQSDRFLDSAGVNRDWPRNRGIFHSADMRFIVWVGEEDALRIISMQPGSGLAQTYLRLQTALEQFDGQLDFAQDSRLG
FLTACPTNLGTAMRASVLIRLPHLSRRPDFRARCARLGLAVRGLHGEHSEARDGIHDVSNATRLGVTERDIYEQLRTGIH
ALMEMESAARKRGHPKVAPGN
>Mature_341_residues
MLLHKHLTPELKSRLERLTTRNGWTLRKTIQSGLDHGDSQMGVYAGDSESYALFSPLLHPIIRDHSGHDLSGHTSDFSLD
GLPQGDLDPTGEFILSTRVRVGRNLARYAFPPAIGARDRAALEAEVVQVLSGLRGHLAGKYHPLASLSEAERLELVHHHV
LFQQSDRFLDSAGVNRDWPRNRGIFHSADMRFIVWVGEEDALRIISMQPGSGLAQTYLRLQTALEQFDGQLDFAQDSRLG
FLTACPTNLGTAMRASVLIRLPHLSRRPDFRARCARLGLAVRGLHGEHSEARDGIHDVSNATRLGVTERDIYEQLRTGIH
ALMEMESAARKRGHPKVAPGN

Specific function: Unknown

COG id: COG3869

COG function: function code E; Arginine kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 phosphagen kinase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI21536286, Length=337, Percent_Identity=40.6528189910979, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI153252003, Length=351, Percent_Identity=34.1880341880342, Blast_Score=224, Evalue=7e-59,
Organism=Homo sapiens, GI153251984, Length=351, Percent_Identity=34.1880341880342, Blast_Score=224, Evalue=7e-59,
Organism=Homo sapiens, GI153251982, Length=351, Percent_Identity=34.1880341880342, Blast_Score=224, Evalue=7e-59,
Organism=Homo sapiens, GI21536288, Length=342, Percent_Identity=37.4269005847953, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI66346730, Length=338, Percent_Identity=36.9822485207101, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI10334859, Length=338, Percent_Identity=36.9822485207101, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI310110654, Length=246, Percent_Identity=40.650406504065, Blast_Score=188, Evalue=5e-48,
Organism=Homo sapiens, GI310110650, Length=182, Percent_Identity=39.5604395604396, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI310110652, Length=157, Percent_Identity=41.4012738853503, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI310110648, Length=187, Percent_Identity=34.2245989304813, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17511011, Length=333, Percent_Identity=43.2432432432432, Blast_Score=285, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI32566409, Length=333, Percent_Identity=43.8438438438438, Blast_Score=284, Evalue=4e-77,
Organism=Caenorhabditis elegans, GI71990551, Length=333, Percent_Identity=43.8438438438438, Blast_Score=283, Evalue=7e-77,
Organism=Caenorhabditis elegans, GI17507069, Length=340, Percent_Identity=41.7647058823529, Blast_Score=269, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI17509681, Length=340, Percent_Identity=41.7647058823529, Blast_Score=269, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI17560974, Length=336, Percent_Identity=41.3690476190476, Blast_Score=261, Evalue=4e-70,
Organism=Caenorhabditis elegans, GI17533117, Length=75, Percent_Identity=41.3333333333333, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24661340, Length=331, Percent_Identity=42.9003021148036, Blast_Score=280, Evalue=1e-75,
Organism=Drosophila melanogaster, GI24661344, Length=331, Percent_Identity=42.9003021148036, Blast_Score=280, Evalue=1e-75,
Organism=Drosophila melanogaster, GI24661336, Length=331, Percent_Identity=42.9003021148036, Blast_Score=280, Evalue=1e-75,
Organism=Drosophila melanogaster, GI221331031, Length=331, Percent_Identity=42.9003021148036, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24661348, Length=331, Percent_Identity=42.9003021148036, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI161082598, Length=331, Percent_Identity=42.9003021148036, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24661332, Length=335, Percent_Identity=42.6865671641791, Blast_Score=272, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24647265, Length=343, Percent_Identity=37.0262390670554, Blast_Score=215, Evalue=3e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000749
- InterPro:   IPR022414
- InterPro:   IPR022415
- InterPro:   IPR014746 [H]

Pfam domain/function: PF00217 ATP-gua_Ptrans [H]

EC number: 2.7.3.2

Molecular weight: Translated: 37911; Mature: 37911

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS00112 GUANIDO_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLHKHLTPELKSRLERLTTRNGWTLRKTIQSGLDHGDSQMGVYAGDSESYALFSPLLHP
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHH
IIRDHSGHDLSGHTSDFSLDGLPQGDLDPTGEFILSTRVRVGRNLARYAFPPAIGARDRA
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCCCCCCCHHH
ALEAEVVQVLSGLRGHLAGKYHPLASLSEAERLELVHHHVLFQQSDRFLDSAGVNRDWPR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NRGIFHSADMRFIVWVGEEDALRIISMQPGSGLAQTYLRLQTALEQFDGQLDFAQDSRLG
CCCCEEECCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
FLTACPTNLGTAMRASVLIRLPHLSRRPDFRARCARLGLAVRGLHGEHSEARDGIHDVSN
EEEECCCHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
ATRLGVTERDIYEQLRTGIHALMEMESAARKRGHPKVAPGN
CHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLLHKHLTPELKSRLERLTTRNGWTLRKTIQSGLDHGDSQMGVYAGDSESYALFSPLLHP
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHH
IIRDHSGHDLSGHTSDFSLDGLPQGDLDPTGEFILSTRVRVGRNLARYAFPPAIGARDRA
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCCCCCCCHHH
ALEAEVVQVLSGLRGHLAGKYHPLASLSEAERLELVHHHVLFQQSDRFLDSAGVNRDWPR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NRGIFHSADMRFIVWVGEEDALRIISMQPGSGLAQTYLRLQTALEQFDGQLDFAQDSRLG
CCCCEEECCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
FLTACPTNLGTAMRASVLIRLPHLSRRPDFRARCARLGLAVRGLHGEHSEARDGIHDVSN
EEEECCCHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
ATRLGVTERDIYEQLRTGIHALMEMESAARKRGHPKVAPGN
CHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; creatine

Specific reaction: ATP + creatine = ADP + phosphocreatine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]