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The map label for this gene is ald [H]

Identifier: 108760086

GI number: 108760086

Start: 5093233

End: 5094357

Strand: Direct

Name: ald [H]

Synonym: MXAN_4146

Alternate gene names: 108760086

Gene position: 5093233-5094357 (Clockwise)

Preceding gene: 108760541

Following gene: 108762328

Centisome position: 55.73

GC content: 68.44

Gene sequence:

>1125_bases
GTGATCGTCGGAGTTCCCAAGGAGATCAAAACCCGCGAGTACCGCGTCGGCATGGTGCCTGCTGGCGCCGCCGCCCTCAT
CGCCGCGGGTCACACGGTCCTGATCGAGACGAACGCCGGCGTTGGCTCCGGCATCCCCGATTCGGAGTACCAGCGCGTCG
GCGCACAGATCATCTCCACCGCGGACGAGGTCTGGAAGCGCTCGGAGATGATCATCAAGGTCAAGGAGCCGATCGCGCCC
GAATACGCGCGCATCCAGCCCGGCCAGATCATCTATACGTACTTCCACCTGGCCGGTGTGGACCCGGAGCTGACCAAGAC
GCTGCTCCAGAAGAAGGCCGCGGCCGTGGCCTATGAAACGCTGCAGCCGGACGACGGCAGCCTGCCGCTGCTCAAGCCCA
TGAGCGAGGTGGCCGGAAAGATGGCCATCCAGGTGGGCGCCAAGTGCCTGGAGCGGGCCCACGGCGGCAAGGGCATCCTC
CTGGGCGGCGTGCCCGGCGTGCGCCGGGGCCGCGTCACCGTCATCGGCGGCGGCGTGGTGGGCCTGTGTGCCGCCAAGGT
GGCGGTGGGCATGGGCGCCGAGGTCACCATCATCGACGTCAACATGGAGCGCCTCACCTACCTGGATGACGTGTTCCTCG
GCCGCGTCGGCGTGCTGGCCTCCGACTCGGAGAGCATCTCCCGCTCCGTGCGCGAGGCCGACCTCGTCGTGGGCGCGGTG
CTCATCCCCGGTCGCAAGGCCCCGAAGCTCGTCTCCGAGGCCCTCATCTCGGAGATGAGCCCGGGCTCCGTGGTGGTCGA
CGTGGCGGTGGACCAGGGTGGCTGCATCGAGACGTGCAAGCCCACCACCCACGACAACCCCACGTTCGAGGTCCACGGCG
TCGTCCACTACTGCGTCGCCAACATGCCCGGCGCCGTGCCGCAGACGTCCACCTACGCCCTCACCAACGTCACCCGCCCC
TATTCGCTCCGGATCGCCAACGTGGGCCTGGCGGCGGCCGTGAAGGAGGACCGCGCCCTCGCGCGTGCGATGAACACCTA
CAACGGCCACGTCACCTACGAGGCCGTCGCGAAAGACATGGGCTACGCCTACATGCCCATCGCGGACGCGCTCGCCGGCA
AGTAA

Upstream 100 bases:

>100_bases
CCAATGGCGCTCATACGGGGCTGTCCGCCCGCGCCTTGATTCCCCCTTGGGCCCTCGTTAGGGTCCGCGCGCTTTTTTAC
GTCCCCTCTCGGAGGCAGTC

Downstream 100 bases:

>100_bases
GCCCGGTAAGCAGGCAAACGATGCAGTCCCTGGCGGGGAGGTTCGGATGGCGACATCCGGCCTCCCCGCTCGTTATCTCT
GCTAGGGAATATGTTTCCCT

Product: alanine dehydrogenase

Products: NA

Alternate protein names: Stage V sporulation protein N [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MIVGVPKEIKTREYRVGMVPAGAAALIAAGHTVLIETNAGVGSGIPDSEYQRVGAQIISTADEVWKRSEMIIKVKEPIAP
EYARIQPGQIIYTYFHLAGVDPELTKTLLQKKAAAVAYETLQPDDGSLPLLKPMSEVAGKMAIQVGAKCLERAHGGKGIL
LGGVPGVRRGRVTVIGGGVVGLCAAKVAVGMGAEVTIIDVNMERLTYLDDVFLGRVGVLASDSESISRSVREADLVVGAV
LIPGRKAPKLVSEALISEMSPGSVVVDVAVDQGGCIETCKPTTHDNPTFEVHGVVHYCVANMPGAVPQTSTYALTNVTRP
YSLRIANVGLAAAVKEDRALARAMNTYNGHVTYEAVAKDMGYAYMPIADALAGK

Sequences:

>Translated_374_residues
MIVGVPKEIKTREYRVGMVPAGAAALIAAGHTVLIETNAGVGSGIPDSEYQRVGAQIISTADEVWKRSEMIIKVKEPIAP
EYARIQPGQIIYTYFHLAGVDPELTKTLLQKKAAAVAYETLQPDDGSLPLLKPMSEVAGKMAIQVGAKCLERAHGGKGIL
LGGVPGVRRGRVTVIGGGVVGLCAAKVAVGMGAEVTIIDVNMERLTYLDDVFLGRVGVLASDSESISRSVREADLVVGAV
LIPGRKAPKLVSEALISEMSPGSVVVDVAVDQGGCIETCKPTTHDNPTFEVHGVVHYCVANMPGAVPQTSTYALTNVTRP
YSLRIANVGLAAAVKEDRALARAMNTYNGHVTYEAVAKDMGYAYMPIADALAGK
>Mature_374_residues
MIVGVPKEIKTREYRVGMVPAGAAALIAAGHTVLIETNAGVGSGIPDSEYQRVGAQIISTADEVWKRSEMIIKVKEPIAP
EYARIQPGQIIYTYFHLAGVDPELTKTLLQKKAAAVAYETLQPDDGSLPLLKPMSEVAGKMAIQVGAKCLERAHGGKGIL
LGGVPGVRRGRVTVIGGGVVGLCAAKVAVGMGAEVTIIDVNMERLTYLDDVFLGRVGVLASDSESISRSVREADLVVGAV
LIPGRKAPKLVSEALISEMSPGSVVVDVAVDQGGCIETCKPTTHDNPTFEVHGVVHYCVANMPGAVPQTSTYALTNVTRP
YSLRIANVGLAAAVKEDRALARAMNTYNGHVTYEAVAKDMGYAYMPIADALAGK

Specific function: This enzyme is a key factor in the assimilation of L- alanine as an energy source through the tricarboxylic acid cycle during sporulation [H]

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=352, Percent_Identity=30.3977272727273, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI122939153, Length=352, Percent_Identity=30.3977272727273, Blast_Score=128, Evalue=8e-30,
Organism=Escherichia coli, GI1787887, Length=346, Percent_Identity=30.0578034682081, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17550456, Length=373, Percent_Identity=29.7587131367292, Blast_Score=136, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR008141 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.4.1.1 [H]

Molecular weight: Translated: 39347; Mature: 39347

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS00837 ALADH_PNT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGVPKEIKTREYRVGMVPAGAAALIAAGHTVLIETNAGVGSGIPDSEYQRVGAQIIST
CCCCCCCHHCCCEEEEEECCCCHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHH
ADEVWKRSEMIIKVKEPIAPEYARIQPGQIIYTYFHLAGVDPELTKTLLQKKAAAVAYET
HHHHHCCCCEEEEECCCCCCCHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
LQPDDGSLPLLKPMSEVAGKMAIQVGAKCLERAHGGKGILLGGVPGVRRGRVTVIGGGVV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCHH
GLCAAKVAVGMGAEVTIIDVNMERLTYLDDVFLGRVGVLASDSESISRSVREADLVVGAV
HHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHEEEEE
LIPGRKAPKLVSEALISEMSPGSVVVDVAVDQGGCIETCKPTTHDNPTFEVHGVVHYCVA
EECCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEHHHHHHHHH
NMPGAVPQTSTYALTNVTRPYSLRIANVGLAAAVKEDRALARAMNTYNGHVTYEAVAKDM
CCCCCCCCCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHC
GYAYMPIADALAGK
CEEEECHHHHHCCC
>Mature Secondary Structure
MIVGVPKEIKTREYRVGMVPAGAAALIAAGHTVLIETNAGVGSGIPDSEYQRVGAQIIST
CCCCCCCHHCCCEEEEEECCCCHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHH
ADEVWKRSEMIIKVKEPIAPEYARIQPGQIIYTYFHLAGVDPELTKTLLQKKAAAVAYET
HHHHHCCCCEEEEECCCCCCCHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
LQPDDGSLPLLKPMSEVAGKMAIQVGAKCLERAHGGKGILLGGVPGVRRGRVTVIGGGVV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCHH
GLCAAKVAVGMGAEVTIIDVNMERLTYLDDVFLGRVGVLASDSESISRSVREADLVVGAV
HHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHEEEEE
LIPGRKAPKLVSEALISEMSPGSVVVDVAVDQGGCIETCKPTTHDNPTFEVHGVVHYCVA
EECCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEHHHHHHHHH
NMPGAVPQTSTYALTNVTRPYSLRIANVGLAAAVKEDRALARAMNTYNGHVTYEAVAKDM
CCCCCCCCCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHC
GYAYMPIADALAGK
CEEEECHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8226620; 9384377 [H]