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The map label for this gene is atoS [H]

Identifier: 108759910

GI number: 108759910

Start: 6238815

End: 6240422

Strand: Reverse

Name: atoS [H]

Synonym: MXAN_4988

Alternate gene names: 108759910

Gene position: 6240422-6238815 (Counterclockwise)

Preceding gene: 108758644

Following gene: 108760996

Centisome position: 68.28

GC content: 69.59

Gene sequence:

>1608_bases
ATGGGGCCCTTGTTCGCCTACAGCCTCGTGCCTGTCCTCTCCGTGTCGCTGCTGCTGTTCTTCACGGCCGTGCTTCGGGG
GCACAACGCGCGAGGCCTGACGCTCTACTGTCTGGCGACCGCAGGGTGGACGGGCGCGCTGCTGCTGCTCTGCATCCCGT
CCATGGCGTGGGTGGGGGAGCGCTTCGTGGCGGGTGGGGCCTTCGTCGCGGCGGCATACCTGCACTCCGCCTATGACGTG
ACCCGGCAGCGCTCCTATCGGCTGGTGGTGCTCGCGTACTGCGTGGCGGTGGTGGTGACGGGCATTGGCGCGTTCCTTCC
CAACGTCCTGCACGGGCCGCTGGCGATGGGGCGAGGCCCCCTGTTCTGGCCCACCATGATGCTCGCCGTGGCGGCGGCGG
GCGTGCCGCTGGTGCATCTGTCGCGCGCGTACCGGGGCGAAGCTCCCGAGCGACGGCCCATCCTCCTCAGTCTGGGCATC
GCCGGGCTGCTCGCGTACCTGGGCAGTATCGGCAACGCCCTGTTGCTGTCGGGCGGGTACGCGTTGCCGTTCGGGATGTA
CCTGGTGCTGGCGGCGCTGCTGGTGCTGGTGCATGTCATCAATGCCCATCAGCCAGCCGCGGACCGACGGCTGCTCGAAC
GCAGCCTCGTCTACTCCGCGGTGGCGGCGGTGTTGTCCGCGGGCTTCCTCTTTGGCGTATTGACGCTGCTGTCGGGCAGC
GGGCAGCCGTTCCTCACCGAGTACCGCGTAGGTGCCTTCTTCCTCCTGGCCCTGGCCGCGCTCGCGTTCGAGCCCGTGCG
TCAGGCGCTTCAGGCCTGGCTGGGGCGCCGGCTCCTCAAGGGCCGGGCCACCAGTGACGAACTGGCCGTGGCGCTCGCTC
GCGAGGAGGCGCGCGCGGACCAATCCGCGCGGTTGGCGGAGTTGGGACAATTCACGTCCGCAGTGGCCCACGAGGTCCGC
AATCCGTTGGGCGTGCTCGCCGCGCACCTCAAGCTGCTGGAGCGAAGGGGCGGGGACCCGGACACGGTGGCGGCCATGCG
GGAGCAGATCGACCGCGCCAGTCACTTCGTGGACGAACTGCTGCGCTATGGACGCCCGCGCCCGCTGGACCTGCGCCGCG
TGGATGTCTCAGCCACCGTCGCGCTGGCGTACTCCACCGCGCGGCAGGGACTTGGCTCGCTCGCGCCCGATGTCGCCTTC
GAGTCCGAGGAGGACGCGTCGCTCACCGTGGAGGCCGACCAGTCCCAGCTCTCACAGGTAATGGTCATCCTGTTGGAGAA
TGCCTTGCTCGCCCTGAGAGACGTGCCCGCACCGCGGTTGAGGACATCCATTGAGCAGGCGAGCGGCCGGTTGCTCGTCC
GGGTGGAGGACAGCGGGCCTGGCATTCCACCGGAACTGCTGCCCCGGCTCTTCCAGCCTTTCGTGACGGGCCGCAAGCGC
GAGGGACCTCGGCCGGGGACAGGCTTGGGGCTGGCCATCGCACGAGGCATCGTCGAACGGCATGGCGGACGTTTGAGTGC
GGGACGCTCGGAAGCCCTGGGGGGCGCGGCGTTGACGTTGGAATTACCCGTGGCGCAGCCTGCCTCGATTTCCGCCGCGC
TGGCCTGA

Upstream 100 bases:

>100_bases
TGCACCCGGATGACTGGGAGACGATGACCCGGGCCATCACCGCCCATACCTCGGCGGCGAGTCCGCCTCACGGCGCTCGC
TGATCTGTCACAGTACGGGC

Downstream 100 bases:

>100_bases
CGCCGGCCTGTCCCTGGCCCGCGGGACGGCAGGGATGTCGGTGAGCGGGCGCAATTTGATGCGATTGAGTCTGCTTCACG
ACGGCCTTCCAAGGATTGCC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MGPLFAYSLVPVLSVSLLLFFTAVLRGHNARGLTLYCLATAGWTGALLLLCIPSMAWVGERFVAGGAFVAAAYLHSAYDV
TRQRSYRLVVLAYCVAVVVTGIGAFLPNVLHGPLAMGRGPLFWPTMMLAVAAAGVPLVHLSRAYRGEAPERRPILLSLGI
AGLLAYLGSIGNALLLSGGYALPFGMYLVLAALLVLVHVINAHQPAADRRLLERSLVYSAVAAVLSAGFLFGVLTLLSGS
GQPFLTEYRVGAFFLLALAALAFEPVRQALQAWLGRRLLKGRATSDELAVALAREEARADQSARLAELGQFTSAVAHEVR
NPLGVLAAHLKLLERRGGDPDTVAAMREQIDRASHFVDELLRYGRPRPLDLRRVDVSATVALAYSTARQGLGSLAPDVAF
ESEEDASLTVEADQSQLSQVMVILLENALLALRDVPAPRLRTSIEQASGRLLVRVEDSGPGIPPELLPRLFQPFVTGRKR
EGPRPGTGLGLAIARGIVERHGGRLSAGRSEALGGAALTLELPVAQPASISAALA

Sequences:

>Translated_535_residues
MGPLFAYSLVPVLSVSLLLFFTAVLRGHNARGLTLYCLATAGWTGALLLLCIPSMAWVGERFVAGGAFVAAAYLHSAYDV
TRQRSYRLVVLAYCVAVVVTGIGAFLPNVLHGPLAMGRGPLFWPTMMLAVAAAGVPLVHLSRAYRGEAPERRPILLSLGI
AGLLAYLGSIGNALLLSGGYALPFGMYLVLAALLVLVHVINAHQPAADRRLLERSLVYSAVAAVLSAGFLFGVLTLLSGS
GQPFLTEYRVGAFFLLALAALAFEPVRQALQAWLGRRLLKGRATSDELAVALAREEARADQSARLAELGQFTSAVAHEVR
NPLGVLAAHLKLLERRGGDPDTVAAMREQIDRASHFVDELLRYGRPRPLDLRRVDVSATVALAYSTARQGLGSLAPDVAF
ESEEDASLTVEADQSQLSQVMVILLENALLALRDVPAPRLRTSIEQASGRLLVRVEDSGPGIPPELLPRLFQPFVTGRKR
EGPRPGTGLGLAIARGIVERHGGRLSAGRSEALGGAALTLELPVAQPASISAALA
>Mature_534_residues
GPLFAYSLVPVLSVSLLLFFTAVLRGHNARGLTLYCLATAGWTGALLLLCIPSMAWVGERFVAGGAFVAAAYLHSAYDVT
RQRSYRLVVLAYCVAVVVTGIGAFLPNVLHGPLAMGRGPLFWPTMMLAVAAAGVPLVHLSRAYRGEAPERRPILLSLGIA
GLLAYLGSIGNALLLSGGYALPFGMYLVLAALLVLVHVINAHQPAADRRLLERSLVYSAVAAVLSAGFLFGVLTLLSGSG
QPFLTEYRVGAFFLLALAALAFEPVRQALQAWLGRRLLKGRATSDELAVALAREEARADQSARLAELGQFTSAVAHEVRN
PLGVLAAHLKLLERRGGDPDTVAAMREQIDRASHFVDELLRYGRPRPLDLRRVDVSATVALAYSTARQGLGSLAPDVAFE
SEEDASLTVEADQSQLSQVMVILLENALLALRDVPAPRLRTSIEQASGRLLVRVEDSGPGIPPELLPRLFQPFVTGRKRE
GPRPGTGLGLAIARGIVERHGGRLSAGRSEALGGAALTLELPVAQPASISAALA

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=242, Percent_Identity=31.8181818181818, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1790436, Length=282, Percent_Identity=31.5602836879433, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788393, Length=238, Percent_Identity=30.672268907563, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790300, Length=205, Percent_Identity=33.6585365853659, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786600, Length=207, Percent_Identity=29.951690821256, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787374, Length=318, Percent_Identity=29.2452830188679, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787894, Length=226, Percent_Identity=29.646017699115, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790346, Length=223, Percent_Identity=28.2511210762332, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=223, Percent_Identity=29.1479820627803, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI145693157, Length=262, Percent_Identity=28.2442748091603, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=29.4354838709677, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081816, Length=252, Percent_Identity=30.1587301587302, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56806; Mature: 56675

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPLFAYSLVPVLSVSLLLFFTAVLRGHNARGLTLYCLATAGWTGALLLLCIPSMAWVGE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHH
RFVAGGAFVAAAYLHSAYDVTRQRSYRLVVLAYCVAVVVTGIGAFLPNVLHGPLAMGRGP
HHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCC
LFWPTMMLAVAAAGVPLVHLSRAYRGEAPERRPILLSLGIAGLLAYLGSIGNALLLSGGY
CHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHCCCCEEECCCC
ALPFGMYLVLAALLVLVHVINAHQPAADRRLLERSLVYSAVAAVLSAGFLFGVLTLLSGS
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GQPFLTEYRVGAFFLLALAALAFEPVRQALQAWLGRRLLKGRATSDELAVALAREEARAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
QSARLAELGQFTSAVAHEVRNPLGVLAAHLKLLERRGGDPDTVAAMREQIDRASHFVDEL
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LRYGRPRPLDLRRVDVSATVALAYSTARQGLGSLAPDVAFESEEDASLTVEADQSQLSQV
HHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHH
MVILLENALLALRDVPAPRLRTSIEQASGRLLVRVEDSGPGIPPELLPRLFQPFVTGRKR
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCC
EGPRPGTGLGLAIARGIVERHGGRLSAGRSEALGGAALTLELPVAQPASISAALA
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHCCCCEEEEEEECCCCCCCCHHHCC
>Mature Secondary Structure 
GPLFAYSLVPVLSVSLLLFFTAVLRGHNARGLTLYCLATAGWTGALLLLCIPSMAWVGE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHH
RFVAGGAFVAAAYLHSAYDVTRQRSYRLVVLAYCVAVVVTGIGAFLPNVLHGPLAMGRGP
HHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCC
LFWPTMMLAVAAAGVPLVHLSRAYRGEAPERRPILLSLGIAGLLAYLGSIGNALLLSGGY
CHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHCCCCEEECCCC
ALPFGMYLVLAALLVLVHVINAHQPAADRRLLERSLVYSAVAAVLSAGFLFGVLTLLSGS
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GQPFLTEYRVGAFFLLALAALAFEPVRQALQAWLGRRLLKGRATSDELAVALAREEARAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
QSARLAELGQFTSAVAHEVRNPLGVLAAHLKLLERRGGDPDTVAAMREQIDRASHFVDEL
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LRYGRPRPLDLRRVDVSATVALAYSTARQGLGSLAPDVAFESEEDASLTVEADQSQLSQV
HHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHH
MVILLENALLALRDVPAPRLRTSIEQASGRLLVRVEDSGPGIPPELLPRLFQPFVTGRKR
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCC
EGPRPGTGLGLAIARGIVERHGGRLSAGRSEALGGAALTLELPVAQPASISAALA
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHCCCCEEEEEEECCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]