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The map label for this gene is ribE

Identifier: 108759881

GI number: 108759881

Start: 5963897

End: 5964400

Strand: Reverse

Name: ribE

Synonym: MXAN_4762

Alternate gene names: 108759881

Gene position: 5964400-5963897 (Counterclockwise)

Preceding gene: 108758043

Following gene: 108757895

Centisome position: 65.26

GC content: 67.66

Gene sequence:

>504_bases
ATGCCTCGCTACTTCGACGGTGACTTTCTACCCCCCAAGGGCCGCTTCGCCATCTGCGTGGCCCGCTTCAACGGCTTCAT
CACCGAGGAGCTGGCCAAGGGCGCCGTGGACACGCTGGTGCGCCACGGCGTGGCCGACGCGGACATCGACGTGTACCGCT
GCCCCGGAACCTATGAGCTGCCCGGTCTGGTTCGGCGCGTGACCGAGACGCGGCAGTACGTGGGCGTCATCACCCTGGGC
GCCGTCATCCGGGGCGGCACGCCGCACTTCGACTATGTGGCCGGCGAGTGCGCCAAGGGCATTGGCGCGGTGGCCTTCGA
GGCCGCGGCCGCCACCCCCGCCAAGACGGTGACTTTTGGCGTGCTGACGACGGACACGGTGGAACAGGCCATCGACCGGG
CGGGCGTGAAGGCTGGGAACAAGGGAGCGGAGGCCACACTGGCCTGCATCGAGATGGTCAATCTGTACGCGAAGATGTCA
GCGACGGACGGAAGGAAGGCGTAG

Upstream 100 bases:

>100_bases
GGGGGACGTGGCGGGCTGACGGCGGCGGCCATCGCGGCTGCGGGGTTTGGCACGCCGTAGCAGGCGACGCCGGGCCCCGG
GGTGGTGTAGGAAGCGCGGC

Downstream 100 bases:

>100_bases
GCCATGGGCGCGCGAAGAACGGGACGTGAGCGTGCGCTGCAGGCGCTCTACCAGTTGGAGATGGCCACCGCGACGACGGC
GGAGGCGCTGGAGTCAGCCT

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MPRYFDGDFLPPKGRFAICVARFNGFITEELAKGAVDTLVRHGVADADIDVYRCPGTYELPGLVRRVTETRQYVGVITLG
AVIRGGTPHFDYVAGECAKGIGAVAFEAAAATPAKTVTFGVLTTDTVEQAIDRAGVKAGNKGAEATLACIEMVNLYAKMS
ATDGRKA

Sequences:

>Translated_167_residues
MPRYFDGDFLPPKGRFAICVARFNGFITEELAKGAVDTLVRHGVADADIDVYRCPGTYELPGLVRRVTETRQYVGVITLG
AVIRGGTPHFDYVAGECAKGIGAVAFEAAAATPAKTVTFGVLTTDTVEQAIDRAGVKAGNKGAEATLACIEMVNLYAKMS
ATDGRKA
>Mature_166_residues
PRYFDGDFLPPKGRFAICVARFNGFITEELAKGAVDTLVRHGVADADIDVYRCPGTYELPGLVRRVTETRQYVGVITLGA
VIRGGTPHFDYVAGECAKGIGAVAFEAAAATPAKTVTFGVLTTDTVEQAIDRAGVKAGNKGAEATLACIEMVNLYAKMSA
TDGRKA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=158, Percent_Identity=48.7341772151899, Blast_Score=140, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6324429, Length=165, Percent_Identity=31.5151515151515, Blast_Score=78, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_MYXXD (Q1D349)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_632924.1
- ProteinModelPortal:   Q1D349
- SMR:   Q1D349
- STRING:   Q1D349
- GeneID:   4102051
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_4762
- TIGR:   MXAN_4762
- eggNOG:   COG0054
- HOGENOM:   HBG311126
- OMA:   KAGNKGW
- PhylomeDB:   Q1D349
- BioCyc:   MXAN246197:MXAN_4762-MONOMER
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 17663; Mature: 17532

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRYFDGDFLPPKGRFAICVARFNGFITEELAKGAVDTLVRHGVADADIDVYRCPGTYEL
CCCCCCCCCCCCCCCEEEEEEHHCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCH
PGLVRRVTETRQYVGVITLGAVIRGGTPHFDYVAGECAKGIGAVAFEAAAATPAKTVTFG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEE
VLTTDTVEQAIDRAGVKAGNKGAEATLACIEMVNLYAKMSATDGRKA
EEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PRYFDGDFLPPKGRFAICVARFNGFITEELAKGAVDTLVRHGVADADIDVYRCPGTYEL
CCCCCCCCCCCCCCEEEEEEHHCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCH
PGLVRRVTETRQYVGVITLGAVIRGGTPHFDYVAGECAKGIGAVAFEAAAATPAKTVTFG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEE
VLTTDTVEQAIDRAGVKAGNKGAEATLACIEMVNLYAKMSATDGRKA
EEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA