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The map label for this gene is cqsS [H]

Identifier: 108759817

GI number: 108759817

Start: 5532294

End: 5532680

Strand: Reverse

Name: cqsS [H]

Synonym: MXAN_4468

Alternate gene names: 108759817

Gene position: 5532680-5532294 (Counterclockwise)

Preceding gene: 108763199

Following gene: 108758906

Centisome position: 60.53

GC content: 64.6

Gene sequence:

>387_bases
TTGGCCCGTCCTGGTGCGGCGCTCAGTCCCGTGAACATCCTTGTCGTCGACGACGATCTCGAACTCTGCACGATGCTCTC
TCGCTTCTTGGAGATGCATGGGTTCACGGTCTACTCGGCGTCCGACGCGCTCCAGGCGCTCGACGTGCTGGAGCGCAACC
AGGTCAGCATGGTCATCACCGACTACGTGATGCCCCATATGGACGGCATCCAGTTCACGGAGATGCTCAAGGCGGACCCC
CGCTTCCAGAGCGTCCCGGTGCTGCTGATGACGGGCAGCGAGGACGGCTCGGTGACGGACCGCGGCCTGCGCAAGGGCGT
GGCCCTGACGCTCCACAAGCCCCTGGACATGGGCCAACTGCTCACCCTGGTCCGCTTCGCGCAATAG

Upstream 100 bases:

>100_bases
CCGCTCACCCCCGTTCGCTTCGACGTCCGCATCCCCATGGGGCCGCGACATATGAAGCCGCGCACTTCGTTGTCAACGCC
GCGCACGGCTGCTACGTTCC

Downstream 100 bases:

>100_bases
CCCACGGCGCACCTCCCGGCAGGGTGCCTCGGGCCGTCCGCTCGCCTACACGGCTACCCTTCCTGGTTGACATCGTTCAG
GCGGCCCTTATGTTGGCGCT

Product: response regulator

Products: NA

Alternate protein names: Cholerae quorum-sensing sensor [H]

Number of amino acids: Translated: 128; Mature: 127

Protein sequence:

>128_residues
MARPGAALSPVNILVVDDDLELCTMLSRFLEMHGFTVYSASDALQALDVLERNQVSMVITDYVMPHMDGIQFTEMLKADP
RFQSVPVLLMTGSEDGSVTDRGLRKGVALTLHKPLDMGQLLTLVRFAQ

Sequences:

>Translated_128_residues
MARPGAALSPVNILVVDDDLELCTMLSRFLEMHGFTVYSASDALQALDVLERNQVSMVITDYVMPHMDGIQFTEMLKADP
RFQSVPVLLMTGSEDGSVTDRGLRKGVALTLHKPLDMGQLLTLVRFAQ
>Mature_127_residues
ARPGAALSPVNILVVDDDLELCTMLSRFLEMHGFTVYSASDALQALDVLERNQVSMVITDYVMPHMDGIQFTEMLKADPR
FQSVPVLLMTGSEDGSVTDRGLRKGVALTLHKPLDMGQLLTLVRFAQ

Specific function: Senses the quorum-sensing autoinducer CAI-1 ((S)-3- hydroxytridecan-4-one) which probably functions as an intragenus signal. The sensory signal is then relayed to luxU and luxO [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=111, Percent_Identity=36.036036036036, Blast_Score=63, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 14125; Mature: 13994

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARPGAALSPVNILVVDDDLELCTMLSRFLEMHGFTVYSASDALQALDVLERNQVSMVIT
CCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCEEEEEHHHHHHHHHHHHCCCCEEEEE
DYVMPHMDGIQFTEMLKADPRFQSVPVLLMTGSEDGSVTDRGLRKGVALTLHKPLDMGQL
HHHHCCCCCCHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHCCEEEEEECCCCHHHH
LTLVRFAQ
HHHHHHCC
>Mature Secondary Structure 
ARPGAALSPVNILVVDDDLELCTMLSRFLEMHGFTVYSASDALQALDVLERNQVSMVIT
CCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCEEEEEHHHHHHHHHHHHCCCCEEEEE
DYVMPHMDGIQFTEMLKADPRFQSVPVLLMTGSEDGSVTDRGLRKGVALTLHKPLDMGQL
HHHHCCCCCCHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHCCEEEEEECCCCHHHH
LTLVRFAQ
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA