Click here to switch to the map view.

The map label for this gene is cspA [H]

Identifier: 108759696

GI number: 108759696

Start: 3890334

End: 3890537

Strand: Direct

Name: cspA [H]

Synonym: MXAN_3345

Alternate gene names: 108759696

Gene position: 3890334-3890537 (Clockwise)

Preceding gene: 108758688

Following gene: 108758722

Centisome position: 42.56

GC content: 63.24

Gene sequence:

>204_bases
ATGGCGACTGGTACCGTGAAGTGGTTCAACGATGCGAAGGGCTTTGGGTTCATCATGCAGGACGGCGGCGGCGAGGACCT
CTTCTGCCACCACACTGCGATTCAGACCCAGGGCTTCCGCACGCTGCAGGAAGGCCAGAAGGTCGAGTTCGACGTGGCCC
GTGGCCCCAAGGGCCTGCAGGCTCAGAACGTTCGCCCGGTCTGA

Upstream 100 bases:

>100_bases
ACTGGCCGGAAACGTGACACATGGCCAAGGCCGCACCCTCACACGGCGTGGCAACCAGCTCAATTCATGAAGCTGGTAGA
GAAAGACGAAGAGAAGCGTA

Downstream 100 bases:

>100_bases
GTACCTACTGAGCGCTCATAGCGCTTAGTCCGAAGGCTCAGTCTCCCCGAGGGAGGCTGGGCCTTTTCCTTTTGTCACCC
CGATGTTCCAGGGCGCGCCT

Product: CspA family cold-shock protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 67; Mature: 66

Protein sequence:

>67_residues
MATGTVKWFNDAKGFGFIMQDGGGEDLFCHHTAIQTQGFRTLQEGQKVEFDVARGPKGLQAQNVRPV

Sequences:

>Translated_67_residues
MATGTVKWFNDAKGFGFIMQDGGGEDLFCHHTAIQTQGFRTLQEGQKVEFDVARGPKGLQAQNVRPV
>Mature_66_residues
ATGTVKWFNDAKGFGFIMQDGGGEDLFCHHTAIQTQGFRTLQEGQKVEFDVARGPKGLQAQNVRPV

Specific function: Inhibits DNA Replication At Both Initiation And Elongation Steps, Most Probably By Binding To The Opened, Single- Stranded Regions At Replication Forks. Plays A Regulatory Role In Chromosomal Replication In Nutrient-Depleted Cells. [C]

COG id: COG1278

COG function: function code K; Cold shock proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CSD (cold-shock) domain [H]

Homologues:

Organism=Homo sapiens, GI224586884, Length=65, Percent_Identity=47.6923076923077, Blast_Score=63, Evalue=5e-11,
Organism=Homo sapiens, GI224586882, Length=65, Percent_Identity=47.6923076923077, Blast_Score=63, Evalue=5e-11,
Organism=Homo sapiens, GI156415990, Length=65, Percent_Identity=47.6923076923077, Blast_Score=63, Evalue=6e-11,
Organism=Homo sapiens, GI34098946, Length=65, Percent_Identity=47.6923076923077, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1787107, Length=67, Percent_Identity=61.1940298507463, Blast_Score=91, Evalue=1e-20,
Organism=Escherichia coli, GI1786841, Length=61, Percent_Identity=59.0163934426229, Blast_Score=82, Evalue=7e-18,
Organism=Escherichia coli, GI2367114, Length=62, Percent_Identity=59.6774193548387, Blast_Score=78, Evalue=1e-16,
Organism=Escherichia coli, GI1789979, Length=65, Percent_Identity=53.8461538461538, Blast_Score=75, Evalue=7e-16,
Organism=Escherichia coli, GI1788126, Length=64, Percent_Identity=54.6875, Blast_Score=74, Evalue=2e-15,
Organism=Escherichia coli, GI1787834, Length=62, Percent_Identity=54.8387096774194, Blast_Score=73, Evalue=4e-15,
Organism=Escherichia coli, GI1787839, Length=62, Percent_Identity=56.4516129032258, Blast_Score=72, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71983217, Length=55, Percent_Identity=45.4545454545455, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71983225, Length=49, Percent_Identity=48.9795918367347, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24658520, Length=61, Percent_Identity=47.5409836065574, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019844
- InterPro:   IPR012156
- InterPro:   IPR011129
- InterPro:   IPR002059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00313 CSD [H]

EC number: NA

Molecular weight: Translated: 7368; Mature: 7237

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: PS00352 COLD_SHOCK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGTVKWFNDAKGFGFIMQDGGGEDLFCHHTAIQTQGFRTLQEGQKVEFDVARGPKGLQ
CCCCCEEECCCCCCEEEEEECCCCCCEEEECCEECCCCCCCCCCCCEEEEEECCCCCCCC
AQNVRPV
CCCCCCC
>Mature Secondary Structure 
ATGTVKWFNDAKGFGFIMQDGGGEDLFCHHTAIQTQGFRTLQEGQKVEFDVARGPKGLQ
CCCCEEECCCCCCEEEEEECCCCCCEEEECCEECCCCCCCCCCCCEEEEEECCCCCCCC
AQNVRPV
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA