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The map label for this gene is ampC [H]

Identifier: 108759551

GI number: 108759551

Start: 6869927

End: 6871144

Strand: Direct

Name: ampC [H]

Synonym: MXAN_5519

Alternate gene names: 108759551

Gene position: 6869927-6871144 (Clockwise)

Preceding gene: 108759010

Following gene: 108760692

Centisome position: 75.17

GC content: 69.46

Gene sequence:

>1218_bases
ATGCCGTTCCAACGCCTCATTCCCAAGATTCCGCGCACTTGGTCGGCTCCGGCACGGCGGACAAATGACATTCCGTCAAT
TCCCGTGCAGGCGTGTGACAGCAAGGCGCGGACGCCCCGACGCCGGCCCTCCCTGGCCGCTCCGGACACATGGTGTAGAA
GGCCCGCCATGCGTTCCGTGCCGAAGCCGCCCCCCGGTGAATTGCTCCAGGATGCCACCCGCGCCTACGTGCGCGGATAT
CGCACGGCGTCCCTCTGCGCCGGCATCACCCAGGGAGGCGTGCATCACGTCGAAGCGCTGCGGAGCAAAGGCGCGCCGCC
CGCTGAAAGCGCCCTCTTCGCGCTGGGCGAGCTGACCCCGGTCTTCACGGGGGCCCTCCTCGCGTTGCTCGTGGACCAGG
GCAAGGCACGGCTCGACATGCCCCTGTCCGAGGTGATTCCCCGGTCGCTGCTCGCGGATGCCACGGCGGGCCGCATCACC
CTGGAGCAACTGGCGACACACACCTCGGGAATGCCCCACCTGCCTCCCAACCTGGAGCAGGACACCCAGACGATGGAGGA
CCCTTTCGGCCATTACGACGCGAGACACTTCGGAGAATTCCTCCAGACCTATCAGCCGGAATGGCCGCCGCCGCGCCGCT
ATGCGCCCTCCATCCTGGGCATGGGCGTGCTGGGCCACGCCCTCTCCCGGCGCGCGGGGCTCAACTACGGACACGCGTTG
AGGGACCTGCTCTTCAAGCCCCTGGGCATGGCCGACACCACGCTGCGCGTGTCCGAGGAACAGGAGCCGCGCCTGACGCC
CGGCCACACGGCGCGAGGCAAACCCATCCCCCAATGGACGTTCCCCGCCCTGCCGGGAGCTGGCGCCGCCTACTCCACCG
CTCCCGACCTGCTCCGCTTCCTCGATGCGAACCTCGGACGGGGCGACGCGGGCATCGTGCGTGCCCTGCAACTGACCCAT
GTGCCGCGCGCGGAGGCGAACCCCGGGAAGATGGGGCTCGGGTGGAGCGTGACGCAGGTGCGCGGTCAGCCAGTGGTGTG
GCGCTCCTCCGTCATCCGGGGCTACACCAGCTTCATGGGCTTCGCCGCCGGAGCGGACGCGGGCGTGGTGCTGCTGGCGA
ACCATGGCTGGTCCTTCTTCTCCGCGCTCCGTGGGCGCATCCCCCTGCAAGCCCCAGGGCTCGAGCTGCTTTCCCGCCTC
CTCCCGACGGAGGCATAG

Upstream 100 bases:

>100_bases
CTGCGCTCGACGAAGTGACGCGTGGCGGAAAACCCAGGGGAAACGGGCGGACGGCAAACGGGCATGGCGTGGACCTCCTG
TTGCCAGGAGGTCATTACAC

Downstream 100 bases:

>100_bases
GTTCGGCGCCCGATGCCGGGGTGAGTCCGCCACACGCGATTGTCTTTCCCTCGCCGGACGCGGCGAAACTGAACGCGGTG
CTGGACTTCGTGGGCGCCCG

Product: beta-lactamase

Products: NA

Alternate protein names: Cephalosporinase [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MPFQRLIPKIPRTWSAPARRTNDIPSIPVQACDSKARTPRRRPSLAAPDTWCRRPAMRSVPKPPPGELLQDATRAYVRGY
RTASLCAGITQGGVHHVEALRSKGAPPAESALFALGELTPVFTGALLALLVDQGKARLDMPLSEVIPRSLLADATAGRIT
LEQLATHTSGMPHLPPNLEQDTQTMEDPFGHYDARHFGEFLQTYQPEWPPPRRYAPSILGMGVLGHALSRRAGLNYGHAL
RDLLFKPLGMADTTLRVSEEQEPRLTPGHTARGKPIPQWTFPALPGAGAAYSTAPDLLRFLDANLGRGDAGIVRALQLTH
VPRAEANPGKMGLGWSVTQVRGQPVVWRSSVIRGYTSFMGFAAGADAGVVLLANHGWSFFSALRGRIPLQAPGLELLSRL
LPTEA

Sequences:

>Translated_405_residues
MPFQRLIPKIPRTWSAPARRTNDIPSIPVQACDSKARTPRRRPSLAAPDTWCRRPAMRSVPKPPPGELLQDATRAYVRGY
RTASLCAGITQGGVHHVEALRSKGAPPAESALFALGELTPVFTGALLALLVDQGKARLDMPLSEVIPRSLLADATAGRIT
LEQLATHTSGMPHLPPNLEQDTQTMEDPFGHYDARHFGEFLQTYQPEWPPPRRYAPSILGMGVLGHALSRRAGLNYGHAL
RDLLFKPLGMADTTLRVSEEQEPRLTPGHTARGKPIPQWTFPALPGAGAAYSTAPDLLRFLDANLGRGDAGIVRALQLTH
VPRAEANPGKMGLGWSVTQVRGQPVVWRSSVIRGYTSFMGFAAGADAGVVLLANHGWSFFSALRGRIPLQAPGLELLSRL
LPTEA
>Mature_404_residues
PFQRLIPKIPRTWSAPARRTNDIPSIPVQACDSKARTPRRRPSLAAPDTWCRRPAMRSVPKPPPGELLQDATRAYVRGYR
TASLCAGITQGGVHHVEALRSKGAPPAESALFALGELTPVFTGALLALLVDQGKARLDMPLSEVIPRSLLADATAGRITL
EQLATHTSGMPHLPPNLEQDTQTMEDPFGHYDARHFGEFLQTYQPEWPPPRRYAPSILGMGVLGHALSRRAGLNYGHALR
DLLFKPLGMADTTLRVSEEQEPRLTPGHTARGKPIPQWTFPALPGAGAAYSTAPDLLRFLDANLGRGDAGIVRALQLTHV
PRAEANPGKMGLGWSVTQVRGQPVVWRSSVIRGYTSFMGFAAGADAGVVLLANHGWSFFSALRGRIPLQAPGLELLSRLL
PTEA

Specific function: Binds Penicillin And Contributes To The Normal Morphology Of Escherichia Coli. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-C beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1786574, Length=285, Percent_Identity=28.0701754385965, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790593, Length=272, Percent_Identity=27.9411764705882, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001586
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 43918; Mature: 43787

Theoretical pI: Translated: 10.53; Mature: 10.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFQRLIPKIPRTWSAPARRTNDIPSIPVQACDSKARTPRRRPSLAAPDTWCRRPAMRSV
CCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCHHCCCCCCCCCCCCHHHHHCCHHHCC
PKPPPGELLQDATRAYVRGYRTASLCAGITQGGVHHVEALRSKGAPPAESALFALGELTP
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
VFTGALLALLVDQGKARLDMPLSEVIPRSLLADATAGRITLEQLATHTSGMPHLPPNLEQ
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCH
DTQTMEDPFGHYDARHFGEFLQTYQPEWPPPRRYAPSILGMGVLGHALSRRAGLNYGHAL
HHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
RDLLFKPLGMADTTLRVSEEQEPRLTPGHTARGKPIPQWTFPALPGAGAAYSTAPDLLRF
HHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LDANLGRGDAGIVRALQLTHVPRAEANPGKMGLGWSVTQVRGQPVVWRSSVIRGYTSFMG
HHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHCCCCCHHHHHHHHHHHHHHH
FAAGADAGVVLLANHGWSFFSALRGRIPLQAPGLELLSRLLPTEA
HHCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
PFQRLIPKIPRTWSAPARRTNDIPSIPVQACDSKARTPRRRPSLAAPDTWCRRPAMRSV
CHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCHHCCCCCCCCCCCCHHHHHCCHHHCC
PKPPPGELLQDATRAYVRGYRTASLCAGITQGGVHHVEALRSKGAPPAESALFALGELTP
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
VFTGALLALLVDQGKARLDMPLSEVIPRSLLADATAGRITLEQLATHTSGMPHLPPNLEQ
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCH
DTQTMEDPFGHYDARHFGEFLQTYQPEWPPPRRYAPSILGMGVLGHALSRRAGLNYGHAL
HHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
RDLLFKPLGMADTTLRVSEEQEPRLTPGHTARGKPIPQWTFPALPGAGAAYSTAPDLLRF
HHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LDANLGRGDAGIVRALQLTHVPRAEANPGKMGLGWSVTQVRGQPVVWRSSVIRGYTSFMG
HHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHCCCCCHHHHHHHHHHHHHHH
FAAGADAGVVLLANHGWSFFSALRGRIPLQAPGLELLSRLLPTEA
HHCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2125210; 10984043; 8012497; 8405939 [H]