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The map label for this gene is uvrB [H]

Identifier: 108759548

GI number: 108759548

Start: 3073312

End: 3075426

Strand: Direct

Name: uvrB [H]

Synonym: MXAN_2632

Alternate gene names: 108759548

Gene position: 3073312-3075426 (Clockwise)

Preceding gene: 108759204

Following gene: 108761605

Centisome position: 33.63

GC content: 66.52

Gene sequence:

>2115_bases
ATGTCGGACTTCCAGCTCGTCAGCGAACACAGTCCCGGAGGCGACCAGCCGAGGGCCATTGGCGAACTCACGCAGGGCCT
TCTGCGGGGTGACCGCTACCAAACCCTCCTGGGCGTCACCGGGTCAGGCAAGACGTTCACGATGGCGAACATCATCGCCA
ACGTGCAGCGGCCCACGCTGGTGATGGCCCATAACAAGACGCTGGCCGCGCAGCTCTACGGCGAATTCAAGGCGCTCTTT
CCGCACAACGCCGTCGAGTACTTCGTCTCGTACTACGACTACTACCAGCCCGAGGCCTACGTTCCGTCGACGGACACCTT
CATCGAGAAGGACTCGTCCATCAACGACAACATCGAACGGATGCGCCACTCGGCCACCCATTCGCTGCGCACGCGGGACG
ACGTCATCATCGTCGCCAGCGTGTCCTGCATCTACGGCCTGGGCGCGGCCCGCAGCTACGTGGAGTTGGCGGTGCGCGCG
GCGGTGGGCGAGGAGATGGGGCGCGACACCTTCATGCGCAAGCTGGTGGAGGCCCAGTACAAGCGCAACGACCTGGACTT
CCACCGCGGCACCTTCCGCGCGCGCGGAGACACCGTCGAGGTGTTTCCCGCGTACGAGGAGGAGCGGGCCGTGCGCGTCA
GCTTCTTTGGCGACGAGGTGGAGCGCGTCACCGAGTTCGACCCGCTGCGCGGCGTGACGTTGGGCGCGCTGGAGAAAATC
GTCATCTTCCCCGCCAGCCACTACGTGGCCGAGGAGGACGTGCGTCGGCGCGCGATCCAGACCATTCGCGACGAGCTGTC
CGAACAACTGCAGACATTCAAGCGCGAGGGCAAGCTGCTCGAGGCTCAGCGGCTGGAGCAGCGCGCCATGTTCGACCTGG
AGATGATTGAGCAGGTCGGCTACTGCAGTGGCATCGAGAACTACTCCCGGCACTTCTCCGGCCGCGCGGCGGGAGAGCCG
CCGCCGTGCCTCATCGACTACTTCCCACGCAACCTGCTGGTGATGCTCGATGAGAGCCACCAGACGGTGCCGCAGATTGG
CGCCATGTACCGCGGCGACCGCGCGCGCAAGGAGACGCTGGTGGGCTTCGGCTTCCGCCTGCCCAGCGCGCTGGACAACC
GCCCGCTCAAGTTCGGTGAGTTCGAGGAGCTGGTGCCCCAGGCCATCTTCGTCTCCGCGACGCCGGCGGAGTACGAGCTG
CAGAAGTCGCAGGGTGTGGTGGTGGAGCAGATCATCCGCCCCACGGGCCTGACCGACCCGGAGGTGGAGATTCGCCCCGT
GGGCAATCAGGTGGACGACCTGCTGGAGGAGGTGCGTCAGCGCGTGTCCCGCAGCGAGCGCGTCCTGGTGACGACGCTCA
CCAAGCGCATGGCGGAAGACCTCACGGAGTACTTCTCCGACGTAGGCGTGCGCGTGCGCTACCTGCACTCGGACATCGAC
GCGATTGAGCGCATGGCCATCATCCGTGACTTGCGCAAGGGCGAGTTCGACGTCCTGGTGGGCATCAACCTGCTGCGCGA
GGGCCTGGACATCCCCGAGGTGTCCCTGGTGGCCATCCTGGACGCGGACAAGGAAGGCTTCCTGCGCAGCCACGTCTCCC
TCATCCAGACGATTGGCCGCGCGGCCCGTAACGTGAGCGGCCGCGTCATCATGTACGCGGACAACGTCACCGACTCCATG
AAGAAGGCCCTGGAGGAGACGACGCGCCGCCGCGACATCCAGCGCGCGTACAACCAGGAGCACGGCATCACCCCGCGTTC
GGTGAAGAGCAACATCACCGACTTGTCCGAGCACGCGGCCTACGATGCGGGTGACGTGGGCGCCCTGCCGATGGCGGCCG
AAGGCGAGGACGACGTCCTCCAGCCGAAGGAAATCAAGCGGCTCATCGAGGAATTCACCAAGGACATGCTCGCCGCCGCG
GACGAGATGCAGTTCGAGAAGGCGGCCGAGTACCGGGACCGCGTGCAGCTCTTGAAGGACATGGACCTGGGGCTCAAGCC
GGCGTCGCGCTCGCTGCTGCGGGCCCCGGCGAAGGCGGCGGAAGCGGAAGCCCCGAAGAAGGGCAAGGGGCGCGGGGGCG
GAGGACGCTCCGCGCGGGCCCGGAGCCGCAAGTAG

Upstream 100 bases:

>100_bases
GGCTGCAATCCCTGGAAGCGCTGAAGCGACAGGACACTTCGAAGTAGCGCGGTGACGAACATCCGGCCTTCCCTCCCGCG
CGGTGTTAAGTCTCGCGGCT

Downstream 100 bases:

>100_bases
GCGGGGGCTGGCATGGACGCGAAGCTCCTGGAGAAGCTGGACGCACTGCCCACCGAGCCCGGCGTGTACCTGATGAAGGA
CCGCCGGGGTCAGGTCATCT

Product: excinuclease ABC subunit B

Products: NA

Alternate protein names: Protein uvrB; Excinuclease ABC subunit B [H]

Number of amino acids: Translated: 704; Mature: 703

Protein sequence:

>704_residues
MSDFQLVSEHSPGGDQPRAIGELTQGLLRGDRYQTLLGVTGSGKTFTMANIIANVQRPTLVMAHNKTLAAQLYGEFKALF
PHNAVEYFVSYYDYYQPEAYVPSTDTFIEKDSSINDNIERMRHSATHSLRTRDDVIIVASVSCIYGLGAARSYVELAVRA
AVGEEMGRDTFMRKLVEAQYKRNDLDFHRGTFRARGDTVEVFPAYEEERAVRVSFFGDEVERVTEFDPLRGVTLGALEKI
VIFPASHYVAEEDVRRRAIQTIRDELSEQLQTFKREGKLLEAQRLEQRAMFDLEMIEQVGYCSGIENYSRHFSGRAAGEP
PPCLIDYFPRNLLVMLDESHQTVPQIGAMYRGDRARKETLVGFGFRLPSALDNRPLKFGEFEELVPQAIFVSATPAEYEL
QKSQGVVVEQIIRPTGLTDPEVEIRPVGNQVDDLLEEVRQRVSRSERVLVTTLTKRMAEDLTEYFSDVGVRVRYLHSDID
AIERMAIIRDLRKGEFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSHVSLIQTIGRAARNVSGRVIMYADNVTDSM
KKALEETTRRRDIQRAYNQEHGITPRSVKSNITDLSEHAAYDAGDVGALPMAAEGEDDVLQPKEIKRLIEEFTKDMLAAA
DEMQFEKAAEYRDRVQLLKDMDLGLKPASRSLLRAPAKAAEAEAPKKGKGRGGGGRSARARSRK

Sequences:

>Translated_704_residues
MSDFQLVSEHSPGGDQPRAIGELTQGLLRGDRYQTLLGVTGSGKTFTMANIIANVQRPTLVMAHNKTLAAQLYGEFKALF
PHNAVEYFVSYYDYYQPEAYVPSTDTFIEKDSSINDNIERMRHSATHSLRTRDDVIIVASVSCIYGLGAARSYVELAVRA
AVGEEMGRDTFMRKLVEAQYKRNDLDFHRGTFRARGDTVEVFPAYEEERAVRVSFFGDEVERVTEFDPLRGVTLGALEKI
VIFPASHYVAEEDVRRRAIQTIRDELSEQLQTFKREGKLLEAQRLEQRAMFDLEMIEQVGYCSGIENYSRHFSGRAAGEP
PPCLIDYFPRNLLVMLDESHQTVPQIGAMYRGDRARKETLVGFGFRLPSALDNRPLKFGEFEELVPQAIFVSATPAEYEL
QKSQGVVVEQIIRPTGLTDPEVEIRPVGNQVDDLLEEVRQRVSRSERVLVTTLTKRMAEDLTEYFSDVGVRVRYLHSDID
AIERMAIIRDLRKGEFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSHVSLIQTIGRAARNVSGRVIMYADNVTDSM
KKALEETTRRRDIQRAYNQEHGITPRSVKSNITDLSEHAAYDAGDVGALPMAAEGEDDVLQPKEIKRLIEEFTKDMLAAA
DEMQFEKAAEYRDRVQLLKDMDLGLKPASRSLLRAPAKAAEAEAPKKGKGRGGGGRSARARSRK
>Mature_703_residues
SDFQLVSEHSPGGDQPRAIGELTQGLLRGDRYQTLLGVTGSGKTFTMANIIANVQRPTLVMAHNKTLAAQLYGEFKALFP
HNAVEYFVSYYDYYQPEAYVPSTDTFIEKDSSINDNIERMRHSATHSLRTRDDVIIVASVSCIYGLGAARSYVELAVRAA
VGEEMGRDTFMRKLVEAQYKRNDLDFHRGTFRARGDTVEVFPAYEEERAVRVSFFGDEVERVTEFDPLRGVTLGALEKIV
IFPASHYVAEEDVRRRAIQTIRDELSEQLQTFKREGKLLEAQRLEQRAMFDLEMIEQVGYCSGIENYSRHFSGRAAGEPP
PCLIDYFPRNLLVMLDESHQTVPQIGAMYRGDRARKETLVGFGFRLPSALDNRPLKFGEFEELVPQAIFVSATPAEYELQ
KSQGVVVEQIIRPTGLTDPEVEIRPVGNQVDDLLEEVRQRVSRSERVLVTTLTKRMAEDLTEYFSDVGVRVRYLHSDIDA
IERMAIIRDLRKGEFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSHVSLIQTIGRAARNVSGRVIMYADNVTDSMK
KALEETTRRRDIQRAYNQEHGITPRSVKSNITDLSEHAAYDAGDVGALPMAAEGEDDVLQPKEIKRLIEEFTKDMLAAAD
EMQFEKAAEYRDRVQLLKDMDLGLKPASRSLLRAPAKAAEAEAPKKGKGRGGGGRSARARSRK

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. Upon binding of the uvrA(2)B(2) complex to a putative damaged site, the DNA

COG id: COG0556

COG function: function code L; Helicase subunit of the DNA excision repair complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI1786996, Length=664, Percent_Identity=59.0361445783133, Blast_Score=777, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR001943
- InterPro:   IPR004807
- InterPro:   IPR009055 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 79217; Mature: 79086

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFQLVSEHSPGGDQPRAIGELTQGLLRGDRYQTLLGVTGSGKTFTMANIIANVQRPTL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHEEEEECCCCCEEHHHHHHHHCCCCEE
VMAHNKTLAAQLYGEFKALFPHNAVEYFVSYYDYYQPEAYVPSTDTFIEKDSSINDNIER
EEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCHHHHH
MRHSATHSLRTRDDVIIVASVSCIYGLGAARSYVELAVRAAVGEEMGRDTFMRKLVEAQY
HHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRNDLDFHRGTFRARGDTVEVFPAYEEERAVRVSFFGDEVERVTEFDPLRGVTLGALEKI
HCCCCCCCCCCEEECCCEEEEECCCCCCCEEEEEECCHHHHHHHHCCCCCCCHHHHHCEE
VIFPASHYVAEEDVRRRAIQTIRDELSEQLQTFKREGKLLEAQRLEQRAMFDLEMIEQVG
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
YCSGIENYSRHFSGRAAGEPPPCLIDYFPRNLLVMLDESHQTVPQIGAMYRGDRARKETL
HHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHH
VGFGFRLPSALDNRPLKFGEFEELVPQAIFVSATPAEYELQKSQGVVVEQIIRPTGLTDP
HHCCCCCCHHHCCCCCCCCCHHHHCCHHEEEECCCCHHHHHHHCCHHHHHHHCCCCCCCC
EVEIRPVGNQVDDLLEEVRQRVSRSERVLVTTLTKRMAEDLTEYFSDVGVRVRYLHSDID
CEEEEECCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHH
AIERMAIIRDLRKGEFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSHVSLIQTIGR
HHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHH
AARNVSGRVIMYADNVTDSMKKALEETTRRRDIQRAYNQEHGITPRSVKSNITDLSEHAA
HHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC
YDAGDVGALPMAAEGEDDVLQPKEIKRLIEEFTKDMLAAADEMQFEKAAEYRDRVQLLKD
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDLGLKPASRSLLRAPAKAAEAEAPKKGKGRGGGGRSARARSRK
CCCCCCHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDFQLVSEHSPGGDQPRAIGELTQGLLRGDRYQTLLGVTGSGKTFTMANIIANVQRPTL
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHEEEEECCCCCEEHHHHHHHHCCCCEE
VMAHNKTLAAQLYGEFKALFPHNAVEYFVSYYDYYQPEAYVPSTDTFIEKDSSINDNIER
EEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCHHHHH
MRHSATHSLRTRDDVIIVASVSCIYGLGAARSYVELAVRAAVGEEMGRDTFMRKLVEAQY
HHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRNDLDFHRGTFRARGDTVEVFPAYEEERAVRVSFFGDEVERVTEFDPLRGVTLGALEKI
HCCCCCCCCCCEEECCCEEEEECCCCCCCEEEEEECCHHHHHHHHCCCCCCCHHHHHCEE
VIFPASHYVAEEDVRRRAIQTIRDELSEQLQTFKREGKLLEAQRLEQRAMFDLEMIEQVG
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
YCSGIENYSRHFSGRAAGEPPPCLIDYFPRNLLVMLDESHQTVPQIGAMYRGDRARKETL
HHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHH
VGFGFRLPSALDNRPLKFGEFEELVPQAIFVSATPAEYELQKSQGVVVEQIIRPTGLTDP
HHCCCCCCHHHCCCCCCCCCHHHHCCHHEEEECCCCHHHHHHHCCHHHHHHHCCCCCCCC
EVEIRPVGNQVDDLLEEVRQRVSRSERVLVTTLTKRMAEDLTEYFSDVGVRVRYLHSDID
CEEEEECCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHH
AIERMAIIRDLRKGEFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSHVSLIQTIGR
HHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHH
AARNVSGRVIMYADNVTDSMKKALEETTRRRDIQRAYNQEHGITPRSVKSNITDLSEHAA
HHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC
YDAGDVGALPMAAEGEDDVLQPKEIKRLIEEFTKDMLAAADEMQFEKAAEYRDRVQLLKD
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDLGLKPASRSLLRAPAKAAEAEAPKKGKGRGGGGRSARARSRK
CCCCCCHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA