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The map label for this gene is tolC [H]

Identifier: 108759473

GI number: 108759473

Start: 5127676

End: 5129022

Strand: Reverse

Name: tolC [H]

Synonym: MXAN_4176

Alternate gene names: 108759473

Gene position: 5129022-5127676 (Counterclockwise)

Preceding gene: 108758005

Following gene: 108763234

Centisome position: 56.12

GC content: 69.64

Gene sequence:

>1347_bases
ATGAACGCCTTCGTGATCGCGGTCGCCCTGGCCGCCGCTCCCTCGGACTCCGGTACACCCATCACCCTGGACCAGGCCCG
CGCGGAGGGCCGGCAGAACGTCGCGGCCATCCAGGCCATGCTGGATGTGGCCATCGCGGACGAGGACGTGAACCTGTCCC
GCTCGGTGCTGCTGCCGCAGCTCTCGCTCGATGCGTCGGCCGGAAAGATCTGGTTCGGCCGCAGGCAGGAGTTCACCACG
GTTCCGGACCCGGCCAACCCGGGAAGCTTCATCCGCAACGCGGTGGAGACGCCCTCCACCAGCACCCAGAACTACGACCT
GGGCTTGTCGCTCACGCAGGTCATCTACGACCGCGCCCGCTGGAAGCAGTTGGAGCAGAGCGGCGTGGTGCGTGACGCGC
AGAAGGGACAGGCGCGGGAAGAGGCGGACACCTCCGAGCTGGAGGCCATCCGCCGCTTCTTCACCCTCTACCGCACCCAG
GCCACGCTCCAGGTGCTGAAGGCCACCGTCGAGCGGAGCGAGCAGCAGGTGGAGCGAGCCCAGGCGCTCTTCCACGCGGG
CCGCACGGGCAAGAATGAAGAGATCACCGCCACGGTGAACCTGGGGACCGACCGCATCAACTACACCGCGATGCTCGGGC
AGCTGGTCAACGACCAGTCCCAGCTCGCCGTGTGGTTGGCCCGGCCGGGCACCGAGGTACTGACGGCCCAGGACCCGGGC
GTGCTCACGACCGAGCCGCCGCCCGCGCCGTCGGTCAACGAGGCGCTCGCGTCGGCCCGCGCGTACCGGCCGCTGCTCAG
GACGCTGGAGCTGCGCATCCGCGCCGCGGAGCTGAAGCAGTCCATTGCCCGCTCGGAGTACCTGCCGCGCCTGATGGCCC
AGGGCCTCTACAACCGCGGCGGTCCGGACGCCTCGCTGGTGTTCACCGAGCCGCGCCTGCAGAACCGCTTTACCGCGGCC
GTCGGGTTGAGCTGGGACCTGTTCACCGGTCTGTCCACGGGGGCGAGCTCCCGTCGCGCCGAGGCGGACATCCGCAAGGC
GCAGCTGACGCTGGAGCAGACGGCGCGGGAAATCGAAGGTGAGGTTCGCGCCGCGCACCGCACGCTGGAGGCCCAGTTGG
AGGCCGCTCGCCTGGCTGCGCAGAACGTCGAGGTCGCTACCCAGGGCCTGGAGATGCAGGAGGCGCGCTTCCGCGCTGGC
GCGGGCTCCACCCTGGAGGTCCGCGACGCGCAGCTGAGCCTGACGCGCGCTGAGCTCGCCTTGTTGGAAAACAGGATCGA
TGTCGAAATCGCCCGCTATTCATTGCAGCGGGCCATGGGCGCCCTGAGCCCGGGAGAGTCGAAATGA

Upstream 100 bases:

>100_bases
CCGGGATGAGTCGTGGGCGTGCGGTGCTGCTGGCGGTGGCGCTGTACGCCATGTACGCGGGCATCTTCCTCATCGGCCTT
CCCGCCCAGGCAGGTGCGCA

Downstream 100 bases:

>100_bases
AGTGGTGGAAGGGTGCCATTGCTGGCGCGTTGTTCCTGGGTGCTGCGGCCATCACCGCGGGCGGGTTGAAGGACCGTCCT
CCGCCGTCGCTCGAAGTCCA

Product: outer membrane efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MNAFVIAVALAAAPSDSGTPITLDQARAEGRQNVAAIQAMLDVAIADEDVNLSRSVLLPQLSLDASAGKIWFGRRQEFTT
VPDPANPGSFIRNAVETPSTSTQNYDLGLSLTQVIYDRARWKQLEQSGVVRDAQKGQAREEADTSELEAIRRFFTLYRTQ
ATLQVLKATVERSEQQVERAQALFHAGRTGKNEEITATVNLGTDRINYTAMLGQLVNDQSQLAVWLARPGTEVLTAQDPG
VLTTEPPPAPSVNEALASARAYRPLLRTLELRIRAAELKQSIARSEYLPRLMAQGLYNRGGPDASLVFTEPRLQNRFTAA
VGLSWDLFTGLSTGASSRRAEADIRKAQLTLEQTAREIEGEVRAAHRTLEAQLEAARLAAQNVEVATQGLEMQEARFRAG
AGSTLEVRDAQLSLTRAELALLENRIDVEIARYSLQRAMGALSPGESK

Sequences:

>Translated_448_residues
MNAFVIAVALAAAPSDSGTPITLDQARAEGRQNVAAIQAMLDVAIADEDVNLSRSVLLPQLSLDASAGKIWFGRRQEFTT
VPDPANPGSFIRNAVETPSTSTQNYDLGLSLTQVIYDRARWKQLEQSGVVRDAQKGQAREEADTSELEAIRRFFTLYRTQ
ATLQVLKATVERSEQQVERAQALFHAGRTGKNEEITATVNLGTDRINYTAMLGQLVNDQSQLAVWLARPGTEVLTAQDPG
VLTTEPPPAPSVNEALASARAYRPLLRTLELRIRAAELKQSIARSEYLPRLMAQGLYNRGGPDASLVFTEPRLQNRFTAA
VGLSWDLFTGLSTGASSRRAEADIRKAQLTLEQTAREIEGEVRAAHRTLEAQLEAARLAAQNVEVATQGLEMQEARFRAG
AGSTLEVRDAQLSLTRAELALLENRIDVEIARYSLQRAMGALSPGESK
>Mature_448_residues
MNAFVIAVALAAAPSDSGTPITLDQARAEGRQNVAAIQAMLDVAIADEDVNLSRSVLLPQLSLDASAGKIWFGRRQEFTT
VPDPANPGSFIRNAVETPSTSTQNYDLGLSLTQVIYDRARWKQLEQSGVVRDAQKGQAREEADTSELEAIRRFFTLYRTQ
ATLQVLKATVERSEQQVERAQALFHAGRTGKNEEITATVNLGTDRINYTAMLGQLVNDQSQLAVWLARPGTEVLTAQDPG
VLTTEPPPAPSVNEALASARAYRPLLRTLELRIRAAELKQSIARSEYLPRLMAQGLYNRGGPDASLVFTEPRLQNRFTAA
VGLSWDLFTGLSTGASSRRAEADIRKAQLTLEQTAREIEGEVRAAHRTLEAQLEAARLAAQNVEVATQGLEMQEARFRAG
AGSTLEVRDAQLSLTRAELALLENRIDVEIARYSLQRAMGALSPGESK

Specific function: May be specialized for signal sequence independent, extracellular secretion in Gram-negative bacteria [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 48922; Mature: 48922

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00033 ENGRAILED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAFVIAVALAAAPSDSGTPITLDQARAEGRQNVAAIQAMLDVAIADEDVNLSRSVLLPQ
CCEEEEEEEEHCCCCCCCCEEEEHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCC
LSLDASAGKIWFGRRQEFTTVPDPANPGSFIRNAVETPSTSTQNYDLGLSLTQVIYDRAR
CCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
WKQLEQSGVVRDAQKGQAREEADTSELEAIRRFFTLYRTQATLQVLKATVERSEQQVERA
HHHHHHCCCHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QALFHAGRTGKNEEITATVNLGTDRINYTAMLGQLVNDQSQLAVWLARPGTEVLTAQDPG
HHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCC
VLTTEPPPAPSVNEALASARAYRPLLRTLELRIRAAELKQSIARSEYLPRLMAQGLYNRG
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GPDASLVFTEPRLQNRFTAAVGLSWDLFTGLSTGASSRRAEADIRKAQLTLEQTAREIEG
CCCCEEEEECCHHHCCHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EVRAAHRTLEAQLEAARLAAQNVEVATQGLEMQEARFRAGAGSTLEVRDAQLSLTRAELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEHHHHHHHHHHHH
LLENRIDVEIARYSLQRAMGALSPGESK
HHHCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNAFVIAVALAAAPSDSGTPITLDQARAEGRQNVAAIQAMLDVAIADEDVNLSRSVLLPQ
CCEEEEEEEEHCCCCCCCCEEEEHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCC
LSLDASAGKIWFGRRQEFTTVPDPANPGSFIRNAVETPSTSTQNYDLGLSLTQVIYDRAR
CCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
WKQLEQSGVVRDAQKGQAREEADTSELEAIRRFFTLYRTQATLQVLKATVERSEQQVERA
HHHHHHCCCHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QALFHAGRTGKNEEITATVNLGTDRINYTAMLGQLVNDQSQLAVWLARPGTEVLTAQDPG
HHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCC
VLTTEPPPAPSVNEALASARAYRPLLRTLELRIRAAELKQSIARSEYLPRLMAQGLYNRG
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GPDASLVFTEPRLQNRFTAAVGLSWDLFTGLSTGASSRRAEADIRKAQLTLEQTAREIEG
CCCCEEEEECCHHHCCHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EVRAAHRTLEAQLEAARLAAQNVEVATQGLEMQEARFRAGAGSTLEVRDAQLSLTRAELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEHHHHHHHHHHHH
LLENRIDVEIARYSLQRAMGALSPGESK
HHHCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]