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The map label for this gene is ntrY [H]

Identifier: 108759412

GI number: 108759412

Start: 6476868

End: 6478604

Strand: Direct

Name: ntrY [H]

Synonym: MXAN_5184

Alternate gene names: 108759412

Gene position: 6476868-6478604 (Clockwise)

Preceding gene: 108763793

Following gene: 108760306

Centisome position: 70.86

GC content: 72.42

Gene sequence:

>1737_bases
ATGCACAAGGCCTCCCCTCGCTGGACGGACTGCACGTGCTTCCACCGGAGGGGACGGCGATGGGAGGACGTCCTTGAGGA
GAACGGCATGCGCTTGAGGACGCGGCTGGCGCTCGCCTTCGCCCTGCTGGCCCTGGTTCCGCTCGCGGTCGTCGTGCCCC
CCACCCTCACCCGCTTGCGCGACACGTTGTCGCGCGAGCTGGACGCGCGCATGGAGGCCGCCACCGCCTCCGCACAGGAG
TCCCTGGAGCGCTCCAGCGCCACGGCCCGCCGCGCGGTGGAGGAGCTGGTGGACAGCACCAGCATGGAGGACCTGGCCCG
CGAGGCCCGCGACCGCCCCACCCGCGCCATCCAGGCCGGCACCGCCGAGGCCCTGATGAAGAGCCGCGGCCTGAGCGTGC
TGGCCCTCTTCGACCGCGAAGGAAGGGTGCTCTCCTCCGGCCACCTGCCCGCGCGCCGGGGAGACCCGGACCCGGCCCTC
TTCGCCGTTACGCAGCAGAAGTCACCCCGGCCCGTGCCAGTGCGCGTGGAGGTGCGCACGGCCTCCGGACTCCGTCAGCT
TCCGGCGCTCGTCACCGCGCGCCCGGTGGACTTCGGGGACCTGCGGCTGTGGGCCGTGGGCGGCGTGCTGCTCGATGAGA
GCCTGGCGCAGCACCTGGCCCGCCTCACCCAGACGCAGGTGACGCTGCTGGCGGGTGACACGCCCCTGGCCAGCGCGGGC
ACGGCCGAACCGCCGACGGTGACGAAGGCGCTGCCGCTGGGAGACGCGGCCACGGTGCGGCTCGTCTTCAGCCGCGCCGC
CGCGCGTGAAGCGGAACAGGGCGTCATGCGCGCCTTCCTCCTGCTGGCGGCGCTGGGCGGCACTTTCGCGGTGCTGCTGG
GCCTGCTGGTGTCCCGGTGGATGACGCGGCCTGTGGAGGCCCTCACCGAGGGCGCCCGGCGCGTGGCCGAAGGCGCGCTG
GAGTCCCAGGTGACGGTGAAGGCCAGCGGCGAGGTGGGCGAGCTGGTGCGGACGTTCAACCGCATGACGTCCGAGCTGAA
GGCCACCACCGAGCGGCTGATGGCCAGCGAGCGCATCGCCGCGTGGCAGGAAGTGGCGCGGCGACTGGCGCACGAAATCA
AGAACCCGCTGACGCCCATCCGCATGTCGCTGGAGACGCTCCAGGCCGCGCAAGAAGCGAAGCACCCGCGCTTCCAAGAC
ATGTTCAAGGAGAGCGCGGGTGTGGTGCTGGAGGAAGTGGACCGGCTGCGCCGCATCGTCGACGAGTTCAGCCACTTCGC
GCGGATGCCCAAGCCGCAGCTGGCGCCCGTGGACCTGGGCGAGCTGGCGCAGAGCGTGCTGGCGCTGTACGCCACGCCTC
CGACCGGCATCCAGATTCTGCCCACGCTCCAGACGGGCGTGGTGGCGCGGGTGGACCGCGACCAGCTCACCCAGGTGCTG
GTGAACCTGGTGAAGAACGCCGAGGAGGCCATGGCGTCCACGGGTGGCACCCTGCGCGTGCGCGTACGCTCCACCGAAGC
CGACGCCATCGTCGAGGTGGAGGACAGCGGCCCCGGCATTCCCCTGGAGCACCGCGCCCGGATCTTCGAGCCCTACTTCA
CCACCAAGGACGGCGGCACCGGCCTGGGGTTGGCCATCGCCTCGCGCATCCTCCAGGAGCACGGCGGCAAACTGGAGGTG
GGCGGAGAGCCCGGCCACGGCGCGCGCTTCAGCCTCGTGCTGCCGCGCGCGGCCTGA

Upstream 100 bases:

>100_bases
GAGCGGGCCCTGGCCCTGGCAGCGTCCGTGCCCCTGGTCCCCCTGTACGTGCAGGGGCTGGGAATGCGCTTCGCTCCGGA
CGTGGGCGGGGTGATGATGG

Downstream 100 bases:

>100_bases
CTCAGACGCTGCGCTCCGCGAAGCGGACGTGGACCAGCGCGGGCAACCGTTCCTTCACCCAGGGCAGCATGTTGAGACCG
TTGTAACCGTACCGGAAGAA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 578; Mature: 578

Protein sequence:

>578_residues
MHKASPRWTDCTCFHRRGRRWEDVLEENGMRLRTRLALAFALLALVPLAVVVPPTLTRLRDTLSRELDARMEAATASAQE
SLERSSATARRAVEELVDSTSMEDLAREARDRPTRAIQAGTAEALMKSRGLSVLALFDREGRVLSSGHLPARRGDPDPAL
FAVTQQKSPRPVPVRVEVRTASGLRQLPALVTARPVDFGDLRLWAVGGVLLDESLAQHLARLTQTQVTLLAGDTPLASAG
TAEPPTVTKALPLGDAATVRLVFSRAAAREAEQGVMRAFLLLAALGGTFAVLLGLLVSRWMTRPVEALTEGARRVAEGAL
ESQVTVKASGEVGELVRTFNRMTSELKATTERLMASERIAAWQEVARRLAHEIKNPLTPIRMSLETLQAAQEAKHPRFQD
MFKESAGVVLEEVDRLRRIVDEFSHFARMPKPQLAPVDLGELAQSVLALYATPPTGIQILPTLQTGVVARVDRDQLTQVL
VNLVKNAEEAMASTGGTLRVRVRSTEADAIVEVEDSGPGIPLEHRARIFEPYFTTKDGGTGLGLAIASRILQEHGGKLEV
GGEPGHGARFSLVLPRAA

Sequences:

>Translated_578_residues
MHKASPRWTDCTCFHRRGRRWEDVLEENGMRLRTRLALAFALLALVPLAVVVPPTLTRLRDTLSRELDARMEAATASAQE
SLERSSATARRAVEELVDSTSMEDLAREARDRPTRAIQAGTAEALMKSRGLSVLALFDREGRVLSSGHLPARRGDPDPAL
FAVTQQKSPRPVPVRVEVRTASGLRQLPALVTARPVDFGDLRLWAVGGVLLDESLAQHLARLTQTQVTLLAGDTPLASAG
TAEPPTVTKALPLGDAATVRLVFSRAAAREAEQGVMRAFLLLAALGGTFAVLLGLLVSRWMTRPVEALTEGARRVAEGAL
ESQVTVKASGEVGELVRTFNRMTSELKATTERLMASERIAAWQEVARRLAHEIKNPLTPIRMSLETLQAAQEAKHPRFQD
MFKESAGVVLEEVDRLRRIVDEFSHFARMPKPQLAPVDLGELAQSVLALYATPPTGIQILPTLQTGVVARVDRDQLTQVL
VNLVKNAEEAMASTGGTLRVRVRSTEADAIVEVEDSGPGIPLEHRARIFEPYFTTKDGGTGLGLAIASRILQEHGGKLEV
GGEPGHGARFSLVLPRAA
>Mature_578_residues
MHKASPRWTDCTCFHRRGRRWEDVLEENGMRLRTRLALAFALLALVPLAVVVPPTLTRLRDTLSRELDARMEAATASAQE
SLERSSATARRAVEELVDSTSMEDLAREARDRPTRAIQAGTAEALMKSRGLSVLALFDREGRVLSSGHLPARRGDPDPAL
FAVTQQKSPRPVPVRVEVRTASGLRQLPALVTARPVDFGDLRLWAVGGVLLDESLAQHLARLTQTQVTLLAGDTPLASAG
TAEPPTVTKALPLGDAATVRLVFSRAAAREAEQGVMRAFLLLAALGGTFAVLLGLLVSRWMTRPVEALTEGARRVAEGAL
ESQVTVKASGEVGELVRTFNRMTSELKATTERLMASERIAAWQEVARRLAHEIKNPLTPIRMSLETLQAAQEAKHPRFQD
MFKESAGVVLEEVDRLRRIVDEFSHFARMPKPQLAPVDLGELAQSVLALYATPPTGIQILPTLQTGVVARVDRDQLTQVL
VNLVKNAEEAMASTGGTLRVRVRSTEADAIVEVEDSGPGIPLEHRARIFEPYFTTKDGGTGLGLAIASRILQEHGGKLEV
GGEPGHGARFSLVLPRAA

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=274, Percent_Identity=33.5766423357664, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=35.3448275862069, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI1790300, Length=250, Percent_Identity=33.2, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788393, Length=289, Percent_Identity=25.9515570934256, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1787894, Length=314, Percent_Identity=30.2547770700637, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1789808, Length=366, Percent_Identity=25.4098360655738, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI48994928, Length=225, Percent_Identity=29.3333333333333, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787374, Length=311, Percent_Identity=24.7588424437299, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1789149, Length=392, Percent_Identity=22.7040816326531, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI145693157, Length=222, Percent_Identity=26.5765765765766, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI87082128, Length=395, Percent_Identity=26.5822784810127, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI87081816, Length=100, Percent_Identity=43, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786600, Length=119, Percent_Identity=34.453781512605, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786783, Length=318, Percent_Identity=23.5849056603774, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788713, Length=226, Percent_Identity=25.6637168141593, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789403, Length=254, Percent_Identity=27.9527559055118, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 62782; Mature: 62782

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKASPRWTDCTCFHRRGRRWEDVLEENGMRLRTRLALAFALLALVPLAVVVPPTLTRLR
CCCCCCCCCCHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
DTLSRELDARMEAATASAQESLERSSATARRAVEELVDSTSMEDLAREARDRPTRAIQAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCC
TAEALMKSRGLSVLALFDREGRVLSSGHLPARRGDPDPALFAVTQQKSPRPVPVRVEVRT
HHHHHHHHCCCEEEEEECCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEC
ASGLRQLPALVTARPVDFGDLRLWAVGGVLLDESLAQHLARLTQTQVTLLAGDTPLASAG
HHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCC
TAEPPTVTKALPLGDAATVRLVFSRAAAREAEQGVMRAFLLLAALGGTFAVLLGLLVSRW
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTRPVEALTEGARRVAEGALESQVTVKASGEVGELVRTFNRMTSELKATTERLMASERIA
HCCHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWQEVARRLAHEIKNPLTPIRMSLETLQAAQEAKHPRFQDMFKESAGVVLEEVDRLRRIV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHH
DEFSHFARMPKPQLAPVDLGELAQSVLALYATPPTGIQILPTLQTGVVARVDRDQLTQVL
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECHHCCHHEECCHHHHHHHH
VNLVKNAEEAMASTGGTLRVRVRSTEADAIVEVEDSGPGIPLEHRARIFEPYFTTKDGGT
HHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHCCCEECCCCCC
GLGLAIASRILQEHGGKLEVGGEPGHGARFSLVLPRAA
CHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCC
>Mature Secondary Structure
MHKASPRWTDCTCFHRRGRRWEDVLEENGMRLRTRLALAFALLALVPLAVVVPPTLTRLR
CCCCCCCCCCHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
DTLSRELDARMEAATASAQESLERSSATARRAVEELVDSTSMEDLAREARDRPTRAIQAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCC
TAEALMKSRGLSVLALFDREGRVLSSGHLPARRGDPDPALFAVTQQKSPRPVPVRVEVRT
HHHHHHHHCCCEEEEEECCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEC
ASGLRQLPALVTARPVDFGDLRLWAVGGVLLDESLAQHLARLTQTQVTLLAGDTPLASAG
HHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCC
TAEPPTVTKALPLGDAATVRLVFSRAAAREAEQGVMRAFLLLAALGGTFAVLLGLLVSRW
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTRPVEALTEGARRVAEGALESQVTVKASGEVGELVRTFNRMTSELKATTERLMASERIA
HCCHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWQEVARRLAHEIKNPLTPIRMSLETLQAAQEAKHPRFQDMFKESAGVVLEEVDRLRRIV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHH
DEFSHFARMPKPQLAPVDLGELAQSVLALYATPPTGIQILPTLQTGVVARVDRDQLTQVL
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECHHCCHHEECCHHHHHHHH
VNLVKNAEEAMASTGGTLRVRVRSTEADAIVEVEDSGPGIPLEHRARIFEPYFTTKDGGT
HHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHCCCEECCCCCC
GLGLAIASRILQEHGGKLEVGGEPGHGARFSLVLPRAA
CHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]