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The map label for this gene is mocR [H]

Identifier: 108759366

GI number: 108759366

Start: 2071622

End: 2073118

Strand: Reverse

Name: mocR [H]

Synonym: MXAN_1746

Alternate gene names: 108759366

Gene position: 2073118-2071622 (Counterclockwise)

Preceding gene: 108763243

Following gene: 108759761

Centisome position: 22.68

GC content: 65.87

Gene sequence:

>1497_bases
ATGGACAGCCCCAGAATCAAGAATGATGAGGGTCCAGTCAGGCGACCGTGGCGCTTCGACTTCACCCTCGAACGGGACAC
GTCCGTGTCGCAGCAGACGCAGCTCACCCGAGCGCTCATCCACGAGATCCAGCGCGGGAGGCTCCCTCCGGGCTCGATGC
TACCGGGAAGCCGAACCCTCGCAGACCAGCTCGGGGTGAATCGGAAGGTGGTCGTCGCGGCGGTTGACGAGCTCGTCGCC
CAGGGGTGGCTTGAGACGCGCCCCGCCTCTGGAACGCGCGTGGCGGCCTCCCTACCGCGCTCGGCGTTCGCTGACGTCGA
ATTGCCCACGCAGCGCAAGTCGGCCTTGCTCCGTCGGGATACCTCCCTCGTGTCGATCACCGATGGGTTGCCGGACCCTC
GGCTCGCGCCGCAGGCGGAGTTGGCGCGCGCATACGCGCGGGCGCTTCGCTCTCTCAGCCGAACAGCGGCGGGCTACGGC
GACGCAGCAGGAGCTCCGAGCCTCCGCGAAGTGATTTCGAGCTTCGTCAATCAGGCTCGCGGGCTCTCCACAACCATCGA
TGAGATCTTCCTCGCACGTGGATCGCAGGGCGCGCTCAGCCTCTACGCACTGGCGATGCTCGAACGTGGCGACGTGGTCG
CTGTGGAGGTGCCAGGTTACGCACCTGCGTGGCGCGCGTTCGAGTTCGCGGGGGCCAAGATCTCGCACATCCCCATCGAT
GGCGAGGGATTGAGGACCGACGTCCTCGAGAAGACGGCGCGGAGGTTGTCGGGCAAGCTGAAGGCCGTCTACGTGACGCC
GCATCATCAGTACCCGACGTCGGTCTCCATGACGCCGGAACGACGGATAAAGCTGCTACAGCTCGCCGAGCACTTCGACT
TCACCATCGTCGAGGACGACTACGACTACGAGTACCACTTCGAAGGTGAGCCGCTGCTACCGCTCCACGCGACCGGAGGA
TCGCGGCGCGTCGTCTACATCGCGTCGCTGTCCAAGCTGCTCGCGCCGACCGTGCGGCTCGGCTACCTCGTCGCGTCGGA
GGGGTGCATTCGCAAGCTGAAGGAAACGCGTGAGCTGCTCGAACGACAAGGTGACGTCGTCCTAGAGCACGCCATCGCGG
AGCTCTTCGAAGACGGGACGCTCCAGCGTCACGCGAGGCGAGCCCGTCGAGAATACAAAGCACGCCGAGATCACCTCCTC
TCGCGGCTCCGCGCGACGCCTGCGCTCGACGAGTGCTTCGACTACTCCGTGCCGGCGGGTGGGTTGGCGCTGTGGCTGAC
CCTGCGCAAGGGAAGCATCGACTCGTTGGTGGCAAGGGCGCGTGAGGAGCACCTGCTGATGGCTCCAGGCTCCACCTATC
TTCCCAAGGGGCGCTTGGACGCCGTTCGGCTCGGGTTCGCCGCGCACACGCCGGACGAGCTTTCGCGAATCTGCGACACG
CTCGCCCGTTGCATTCCAAGCCGACCTGGTCTGCGCCCCAATCTTCGGACCAGTTGA

Upstream 100 bases:

>100_bases
CTCGACGCTGTACGCAGTTGAATATGCCGGGGTGTTGATGGTTGCCTCCTGGATCGCGCACGTCCTTGCGCGCGTTCGTA
AATGGCAAGAGACTGGCCCC

Downstream 100 bases:

>100_bases
AGCGAGAGCGAGAGTCCTCGCTGACCGGAAGCTGGCGAAGAGCGGCGGCCAGAAGGATGAGCTGCTCTCCGTGCGCTGGG
AAGAAATACAGGAGGAAGGC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MDSPRIKNDEGPVRRPWRFDFTLERDTSVSQQTQLTRALIHEIQRGRLPPGSMLPGSRTLADQLGVNRKVVVAAVDELVA
QGWLETRPASGTRVAASLPRSAFADVELPTQRKSALLRRDTSLVSITDGLPDPRLAPQAELARAYARALRSLSRTAAGYG
DAAGAPSLREVISSFVNQARGLSTTIDEIFLARGSQGALSLYALAMLERGDVVAVEVPGYAPAWRAFEFAGAKISHIPID
GEGLRTDVLEKTARRLSGKLKAVYVTPHHQYPTSVSMTPERRIKLLQLAEHFDFTIVEDDYDYEYHFEGEPLLPLHATGG
SRRVVYIASLSKLLAPTVRLGYLVASEGCIRKLKETRELLERQGDVVLEHAIAELFEDGTLQRHARRARREYKARRDHLL
SRLRATPALDECFDYSVPAGGLALWLTLRKGSIDSLVARAREEHLLMAPGSTYLPKGRLDAVRLGFAAHTPDELSRICDT
LARCIPSRPGLRPNLRTS

Sequences:

>Translated_498_residues
MDSPRIKNDEGPVRRPWRFDFTLERDTSVSQQTQLTRALIHEIQRGRLPPGSMLPGSRTLADQLGVNRKVVVAAVDELVA
QGWLETRPASGTRVAASLPRSAFADVELPTQRKSALLRRDTSLVSITDGLPDPRLAPQAELARAYARALRSLSRTAAGYG
DAAGAPSLREVISSFVNQARGLSTTIDEIFLARGSQGALSLYALAMLERGDVVAVEVPGYAPAWRAFEFAGAKISHIPID
GEGLRTDVLEKTARRLSGKLKAVYVTPHHQYPTSVSMTPERRIKLLQLAEHFDFTIVEDDYDYEYHFEGEPLLPLHATGG
SRRVVYIASLSKLLAPTVRLGYLVASEGCIRKLKETRELLERQGDVVLEHAIAELFEDGTLQRHARRARREYKARRDHLL
SRLRATPALDECFDYSVPAGGLALWLTLRKGSIDSLVARAREEHLLMAPGSTYLPKGRLDAVRLGFAAHTPDELSRICDT
LARCIPSRPGLRPNLRTS
>Mature_498_residues
MDSPRIKNDEGPVRRPWRFDFTLERDTSVSQQTQLTRALIHEIQRGRLPPGSMLPGSRTLADQLGVNRKVVVAAVDELVA
QGWLETRPASGTRVAASLPRSAFADVELPTQRKSALLRRDTSLVSITDGLPDPRLAPQAELARAYARALRSLSRTAAGYG
DAAGAPSLREVISSFVNQARGLSTTIDEIFLARGSQGALSLYALAMLERGDVVAVEVPGYAPAWRAFEFAGAKISHIPID
GEGLRTDVLEKTARRLSGKLKAVYVTPHHQYPTSVSMTPERRIKLLQLAEHFDFTIVEDDYDYEYHFEGEPLLPLHATGG
SRRVVYIASLSKLLAPTVRLGYLVASEGCIRKLKETRELLERQGDVVLEHAIAELFEDGTLQRHARRARREYKARRDHLL
SRLRATPALDECFDYSVPAGGLALWLTLRKGSIDSLVARAREEHLLMAPGSTYLPKGRLDAVRLGFAAHTPDELSRICDT
LARCIPSRPGLRPNLRTS

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=399, Percent_Identity=22.5563909774436, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI33469970, Length=399, Percent_Identity=22.5563909774436, Blast_Score=95, Evalue=2e-19,
Organism=Escherichia coli, GI1787710, Length=435, Percent_Identity=27.816091954023, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1790797, Length=458, Percent_Identity=26.8558951965066, Blast_Score=123, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6321236, Length=403, Percent_Identity=23.0769230769231, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 55100; Mature: 55100

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSPRIKNDEGPVRRPWRFDFTLERDTSVSQQTQLTRALIHEIQRGRLPPGSMLPGSRTL
CCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
ADQLGVNRKVVVAAVDELVAQGWLETRPASGTRVAASLPRSAFADVELPTQRKSALLRRD
HHHHCCCCEEHHHHHHHHHHHCHHHCCCCCCCCHHHHCCCHHHCCCCCCHHHHHHHHHCC
TSLVSITDGLPDPRLAPQAELARAYARALRSLSRTAAGYGDAAGAPSLREVISSFVNQAR
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
GLSTTIDEIFLARGSQGALSLYALAMLERGDVVAVEVPGYAPAWRAFEFAGAKISHIPID
CCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCCEEEECCCC
GEGLRTDVLEKTARRLSGKLKAVYVTPHHQYPTSVSMTPERRIKLLQLAEHFDFTIVEDD
CCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECC
YDYEYHFEGEPLLPLHATGGSRRVVYIASLSKLLAPTVRLGYLVASEGCIRKLKETRELL
CCCEEEECCCCCEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
ERQGDVVLEHAIAELFEDGTLQRHARRARREYKARRDHLLSRLRATPALDECFDYSVPAG
HHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCC
GLALWLTLRKGSIDSLVARAREEHLLMAPGSTYLPKGRLDAVRLGFAAHTPDELSRICDT
CEEEEEEECCCCHHHHHHHHHHCCEEECCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHH
LARCIPSRPGLRPNLRTS
HHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MDSPRIKNDEGPVRRPWRFDFTLERDTSVSQQTQLTRALIHEIQRGRLPPGSMLPGSRTL
CCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
ADQLGVNRKVVVAAVDELVAQGWLETRPASGTRVAASLPRSAFADVELPTQRKSALLRRD
HHHHCCCCEEHHHHHHHHHHHCHHHCCCCCCCCHHHHCCCHHHCCCCCCHHHHHHHHHCC
TSLVSITDGLPDPRLAPQAELARAYARALRSLSRTAAGYGDAAGAPSLREVISSFVNQAR
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
GLSTTIDEIFLARGSQGALSLYALAMLERGDVVAVEVPGYAPAWRAFEFAGAKISHIPID
CCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCCEEEECCCC
GEGLRTDVLEKTARRLSGKLKAVYVTPHHQYPTSVSMTPERRIKLLQLAEHFDFTIVEDD
CCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECC
YDYEYHFEGEPLLPLHATGGSRRVVYIASLSKLLAPTVRLGYLVASEGCIRKLKETRELL
CCCEEEECCCCCEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
ERQGDVVLEHAIAELFEDGTLQRHARRARREYKARRDHLLSRLRATPALDECFDYSVPAG
HHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCC
GLALWLTLRKGSIDSLVARAREEHLLMAPGSTYLPKGRLDAVRLGFAAHTPDELSRICDT
CEEEEEEECCCCHHHHHHHHHHCCEEECCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHH
LARCIPSRPGLRPNLRTS
HHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]