Click here to switch to the map view.

The map label for this gene is nusA [H]

Identifier: 108759193

GI number: 108759193

Start: 2396577

End: 2398277

Strand: Direct

Name: nusA [H]

Synonym: MXAN_2066

Alternate gene names: 108759193

Gene position: 2396577-2398277 (Clockwise)

Preceding gene: 108761060

Following gene: 108757034

Centisome position: 26.22

GC content: 67.31

Gene sequence:

>1701_bases
ATGCCCACGCAGCAAGCCAACCCGAGTGTCAACCTCAACCTCGTCCTGGACCAGGTCGCCAAGGACAAGGGCATCGACCG
GGCTGTGCTGATTGCCACGCTCGAAGACGCGATGAAGACCGCGGCCAAGAAGCACTTTGGCCAGGACCGCGAGCTCGAGG
CGAAGTACGACCCGGACAAGGGCGTCGTGGAGCTGTTCCAGGCCATCACCGTGGTCGAGGAGATTGTCGATCCGGTCCAG
GCGGTGAATCAGATCTCCCTGGTCGAGGCCCACAAGAAGGGCATGGAAGTGGAGCCGGGCGACGAGCTCGTGTTCCAGAT
CTTCTACCGGGACGAGGACGCCGCCGAGGCCAAGGCCCAGGACGACCAGTACGGTGACATCCTCCGCCTGAAGACCTTCC
GTCGCGGCTTCGGCCGCATCGCCGCGCAGACGGCCAAGCAGGTCATCCTGCAGCGCACGCGCGACGCGGAGCGGGAGAAC
GTCTTCAACGAGTACCGCGACCGGAAGAACGAAATCGTCACCGGCATCGCCCGCCGGTTCGAGCGCGGCAACATCATCGT
GGACCTGGGCCGCGCCGAGGCCGTGCTGCCGGTGCGCGAGCAGGTCCCGCGTGAGACCTACCGTCCCGGCGACCGCGTCC
AGGCCTACGTGCTGGACGTGCTCCGTGAGTCCAAGGGCCCCCAGATTGTCCTCAGCCGCGCGTCCGTCAACCTGCTCACC
AAGCTGTTCGAGATGGAGGTGCCGGAAATCGCCGAAGGCATCGTCGTCATCGAGGCGGCGGCGCGTGAGCCGGGCGGCCG
GGCGAAGATTGCCGTGTCCAGCCGGGACTCGGACGTGGACCCCGTGGGCGCCTGCGTCGGTATGAAGGGCAGCCGTGTTC
AGGCGGTGGTGCAGGAGCTGCGCGGCGAGAAGATCGACATCGTCCCCTTCGACGAGGATCCGGCCCGCTTCGTGTGCTCG
GCGCTGGCCCCGGCGGAGGTCAGCCGCGTCATCATCGACGAGGCCAACCACGCCATGGAGCTCATCGTCCCGGACGACCA
GCTCAGCCTGGCCATTGGCCGTCGCGGTCAGAACGTCCGCTTGGCAGCCCAGCTGACCGGCTGGAAGCTCGACATCAACA
GCGAGAGCCGGGTCCGGGAGCTGCGCGAGTTCGCCAACCGCTCGCTGGGCTCGCTGCCCGGCGTCAACGAGATGCTGGTG
GAGACGCTCTACGCGCACGGCTTCCGTCAGGCCCGGGACATCGCCGAGGCCAACGCGGAGTTGCTGGCGCAGCTGCCCGG
CATCGACCCGGCCCGCATCCCCTCCATGCAGGAAGCCGCCCGGACCCGGATGGTCGAGGATCAGGCGGAACTGTCGCGCA
TGGATTATGAAAGAGAGCAGGCCCGCATCGCGGAGGCTCGGCGGCATCCGGACGAGCTCAGCCAGCCCGAGCGCATGGCG
CGCGTGCGTGGCGTCGGTGAGAAGACCATCGAGCAGCTCATCCTCGCGGGGTACCGCTCGGTGGAGGACATCGCCAACGA
GAAGGACCTGGCGAAGCTGGGCGATGTTCCGGGTGTGGGTATCAAGAAGGCCCGCCAGCTGAAGAGCGCGGCGGAAAACT
ATCTGGTGGAGGAAGCCAAGCTGCGCGCGGAGCTGAATGCCGAGCGCGGCGCCATGACGGTGGCACTTGAGGGTGGCGCA
GAAGCCACCAAGGCGCCGTAA

Upstream 100 bases:

>100_bases
AGGACATCGCCAAGGCGAACCTGGAGTTCCAGTTCTAGACGTCGACATACAGGGTGCCCCTCCGCGCGAGGGCGCCCGTG
GACCCTTTTAGGAGAAGACC

Downstream 100 bases:

>100_bases
GCTAAGCGAGGGAGGGGACGTGCGGCGCCCGGCTGGCCGGCCCAGGCCGGAAGTTCAGAATGCGGGGTCAGGTCCGGTCC
GGACGTGCGTCGGATGCGGG

Product: transcription termination factor NusA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 565

Protein sequence:

>566_residues
MPTQQANPSVNLNLVLDQVAKDKGIDRAVLIATLEDAMKTAAKKHFGQDRELEAKYDPDKGVVELFQAITVVEEIVDPVQ
AVNQISLVEAHKKGMEVEPGDELVFQIFYRDEDAAEAKAQDDQYGDILRLKTFRRGFGRIAAQTAKQVILQRTRDAEREN
VFNEYRDRKNEIVTGIARRFERGNIIVDLGRAEAVLPVREQVPRETYRPGDRVQAYVLDVLRESKGPQIVLSRASVNLLT
KLFEMEVPEIAEGIVVIEAAAREPGGRAKIAVSSRDSDVDPVGACVGMKGSRVQAVVQELRGEKIDIVPFDEDPARFVCS
ALAPAEVSRVIIDEANHAMELIVPDDQLSLAIGRRGQNVRLAAQLTGWKLDINSESRVRELREFANRSLGSLPGVNEMLV
ETLYAHGFRQARDIAEANAELLAQLPGIDPARIPSMQEAARTRMVEDQAELSRMDYEREQARIAEARRHPDELSQPERMA
RVRGVGEKTIEQLILAGYRSVEDIANEKDLAKLGDVPGVGIKKARQLKSAAENYLVEEAKLRAELNAERGAMTVALEGGA
EATKAP

Sequences:

>Translated_566_residues
MPTQQANPSVNLNLVLDQVAKDKGIDRAVLIATLEDAMKTAAKKHFGQDRELEAKYDPDKGVVELFQAITVVEEIVDPVQ
AVNQISLVEAHKKGMEVEPGDELVFQIFYRDEDAAEAKAQDDQYGDILRLKTFRRGFGRIAAQTAKQVILQRTRDAEREN
VFNEYRDRKNEIVTGIARRFERGNIIVDLGRAEAVLPVREQVPRETYRPGDRVQAYVLDVLRESKGPQIVLSRASVNLLT
KLFEMEVPEIAEGIVVIEAAAREPGGRAKIAVSSRDSDVDPVGACVGMKGSRVQAVVQELRGEKIDIVPFDEDPARFVCS
ALAPAEVSRVIIDEANHAMELIVPDDQLSLAIGRRGQNVRLAAQLTGWKLDINSESRVRELREFANRSLGSLPGVNEMLV
ETLYAHGFRQARDIAEANAELLAQLPGIDPARIPSMQEAARTRMVEDQAELSRMDYEREQARIAEARRHPDELSQPERMA
RVRGVGEKTIEQLILAGYRSVEDIANEKDLAKLGDVPGVGIKKARQLKSAAENYLVEEAKLRAELNAERGAMTVALEGGA
EATKAP
>Mature_565_residues
PTQQANPSVNLNLVLDQVAKDKGIDRAVLIATLEDAMKTAAKKHFGQDRELEAKYDPDKGVVELFQAITVVEEIVDPVQA
VNQISLVEAHKKGMEVEPGDELVFQIFYRDEDAAEAKAQDDQYGDILRLKTFRRGFGRIAAQTAKQVILQRTRDAERENV
FNEYRDRKNEIVTGIARRFERGNIIVDLGRAEAVLPVREQVPRETYRPGDRVQAYVLDVLRESKGPQIVLSRASVNLLTK
LFEMEVPEIAEGIVVIEAAAREPGGRAKIAVSSRDSDVDPVGACVGMKGSRVQAVVQELRGEKIDIVPFDEDPARFVCSA
LAPAEVSRVIIDEANHAMELIVPDDQLSLAIGRRGQNVRLAAQLTGWKLDINSESRVRELREFANRSLGSLPGVNEMLVE
TLYAHGFRQARDIAEANAELLAQLPGIDPARIPSMQEAARTRMVEDQAELSRMDYEREQARIAEARRHPDELSQPERMAR
VRGVGEKTIEQLILAGYRSVEDIANEKDLAKLGDVPGVGIKKARQLKSAAENYLVEEAKLRAELNAERGAMTVALEGGAE
ATKAP

Specific function: Participates in both the termination and antitermination of transcription. Interacts with RNA polymerase and binds RNA [H]

COG id: COG0195

COG function: function code K; Transcription elongation factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Escherichia coli, GI1789560, Length=525, Percent_Identity=34.8571428571429, Blast_Score=291, Evalue=1e-79,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1612 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010995
- InterPro:   IPR004087
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004088
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013735
- InterPro:   IPR010214
- InterPro:   IPR010213 [H]

Pfam domain/function: PF08529 NusA_N; PF00575 S1 [H]

EC number: NA

Molecular weight: Translated: 62714; Mature: 62583

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50084 KH_TYPE_1 ; PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTQQANPSVNLNLVLDQVAKDKGIDRAVLIATLEDAMKTAAKKHFGQDRELEAKYDPDK
CCCCCCCCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
GVVELFQAITVVEEIVDPVQAVNQISLVEAHKKGMEVEPGDELVFQIFYRDEDAAEAKAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEEECCCCHHHHHCC
DDQYGDILRLKTFRRGFGRIAAQTAKQVILQRTRDAERENVFNEYRDRKNEIVTGIARRF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
ERGNIIVDLGRAEAVLPVREQVPRETYRPGDRVQAYVLDVLRESKGPQIVLSRASVNLLT
CCCCEEEEECCCCCCCCHHHHCCHHHCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHH
KLFEMEVPEIAEGIVVIEAAAREPGGRAKIAVSSRDSDVDPVGACVGMKGSRVQAVVQEL
HHHHCCCHHHHCCEEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHH
RGEKIDIVPFDEDPARFVCSALAPAEVSRVIIDEANHAMELIVPDDQLSLAIGRRGQNVR
CCCEEEEEECCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCHHHHCCCCCCCEE
LAAQLTGWKLDINSESRVRELREFANRSLGSLPGVNEMLVETLYAHGFRQARDIAEANAE
EEEEECCEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAQLPGIDPARIPSMQEAARTRMVEDQAELSRMDYEREQARIAEARRHPDELSQPERMA
HHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHH
RVRGVGEKTIEQLILAGYRSVEDIANEKDLAKLGDVPGVGIKKARQLKSAAENYLVEEAK
HHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LRAELNAERGAMTVALEGGAEATKAP
HHHHHCCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure 
PTQQANPSVNLNLVLDQVAKDKGIDRAVLIATLEDAMKTAAKKHFGQDRELEAKYDPDK
CCCCCCCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
GVVELFQAITVVEEIVDPVQAVNQISLVEAHKKGMEVEPGDELVFQIFYRDEDAAEAKAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEEECCCCHHHHHCC
DDQYGDILRLKTFRRGFGRIAAQTAKQVILQRTRDAERENVFNEYRDRKNEIVTGIARRF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
ERGNIIVDLGRAEAVLPVREQVPRETYRPGDRVQAYVLDVLRESKGPQIVLSRASVNLLT
CCCCEEEEECCCCCCCCHHHHCCHHHCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHH
KLFEMEVPEIAEGIVVIEAAAREPGGRAKIAVSSRDSDVDPVGACVGMKGSRVQAVVQEL
HHHHCCCHHHHCCEEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHH
RGEKIDIVPFDEDPARFVCSALAPAEVSRVIIDEANHAMELIVPDDQLSLAIGRRGQNVR
CCCEEEEEECCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCHHHHCCCCCCCEE
LAAQLTGWKLDINSESRVRELREFANRSLGSLPGVNEMLVETLYAHGFRQARDIAEANAE
EEEEECCEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAQLPGIDPARIPSMQEAARTRMVEDQAELSRMDYEREQARIAEARRHPDELSQPERMA
HHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHH
RVRGVGEKTIEQLILAGYRSVEDIANEKDLAKLGDVPGVGIKKARQLKSAAENYLVEEAK
HHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LRAELNAERGAMTVALEGGAEATKAP
HHHHHCCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]