Click here to switch to the map view.

The map label for this gene is norR [H]

Identifier: 108758998

GI number: 108758998

Start: 4923996

End: 4925888

Strand: Direct

Name: norR [H]

Synonym: MXAN_4020

Alternate gene names: 108758998

Gene position: 4923996-4925888 (Clockwise)

Preceding gene: 108757753

Following gene: 108759813

Centisome position: 53.87

GC content: 66.61

Gene sequence:

>1893_bases
ATGGCCAGCCTCACCGTCCGCACCCCCGATGGCAAGATCCGCGCAGTCTCCCTGCACAAGCGCCTCACCAGCATTGGCCG
GGGCCCGGACAACGACATCCCGCTGGAGGACACCTCCGTGCCCGCCAGCGCCCTGCACGTCACCTTCGACGGCACGCGCT
ACGAGGTAGGCAGCCTGGGCGCCACCTTCCACGTCAACGGCAAGAAGCGCGACGCCCATGCGCTCTCCACCGGCGACGTG
GTCCGCGTGGGCCACACCGAGCTGATCTTCGCCCGGGACGACGCGCCCCGTGCACCGCCGCTACCCGCGTCCCCTCCGCG
CGAGCTGATTCACACGTCCAACCCCGACTCGCACACCTCGGAGCTGCCCGGCGTCCCCGGCCGCGAGCTGCTGCTGCTGC
GCCGGCTCACCGCGTTCAGCGAGCGGCTGCTGGGGCTCTACGACTTGGAGCGCCTCCTGGAGGGCCTGATGGACGAGGCC
ATCGAGGTGACGCGCGCCGACAAGGGCTTCCTCATCCTGATGGAGAACGGGGACCCGCGCGTGAAGGTGGCGCGCAACGT
GTCCCGGGAGAACATCGAGGACGCGGTGGAGAAGGATAAAATCTCCGACTCCATCATCGCCAAGGTGGTGAAGGAGCAGA
AGGCGCTCATCGTCGCGGACGCGCTGGACTCGCCGGAGTTCAACAAGAGCGAGTCGGTGGTGAACCTGCGCGTCCACTCC
GTCATGTGCGTGCCGCTGATGCAGAAGGGCGACCTCTTCGGTGTCCTCTACGTGGGCAATGACCGGCTGGTGAACCGGTT
CGAGCCCAAGAGCGCGGACATGCTCACCATCTTCGCGGCGCAGGCGTCGCTCATTCTCCAGAACGCGATGCTGGTGAGCG
ACCTCAAGCTCGACAACACCGAGCTGCGCCGCAAGCTGGAGGACCAGCGCTATGGCGACATCGTCGGCGCGTGCCAGGGC
ATGCGGGACGTGTACAAGCGCATCGACAAGATCGCGCCCACGGACATCTCCGTGCTCATTACCGGTGAGACGGGCACCGG
CAAGGAGCTCATCGCGCGGGAAATCCACCGCCGCTCGACGCGCGCGAAGGGCCCCTTCATCACCATCAACTGCGGCGCGA
TTCCGGAGAACCTGCTGGAGAGCGAGCTGTTCGGCCACGTGAAGGGCGCCTTCACCGGCGCGGTGGCCACCAAGGCCGGC
AAGTTCCAGGCGGCCATTGGCGGCACGCTCTTCCTGGACGAAATCGGTGAGATGCCGCTGCAGCTCCAGGTGAAGCTCTT
GCGCGCGCTCCAGGAGAAGGTCGTCTACAAGGTCGGCGACAACCGCGGCGAGCCGGTGGACATCCGCGTGGTGGCGGCCA
CCAACAAGGTGCTCGAGGACGAGGTGAAGAAGAACACCTTCCGCGAGGACCTCTACTACCGTCTCAACGTCGTCACGCTG
AAGCTGCCGCCCCTGCGAGAGCGCGGCGAGGACGTGGTGGTGCTCGGCCGCTTCTTCCTCCAGAAGTACGCCCGCGAGTT
CAGCTCCAAGGCCCGCGGCTTCACCCCCTCCGCCACCGTGTCCATGCGCAAGTACGGCTGGCCGGGCAACATCCGCGAGT
TGGAGAACCGGCTCAAGAAGGCGGTGGTGCTCGCGGACAAGCCGCTCCTGGGGCCGGATGACCTGGACCTGAAGCCGGAG
AACCTGGAGCCCATCATGCCGCTGCTCCAGGCCAAGGAAGAGTTCCAGAAGCGTTACATCAACGAGGTGCTCGCCCGGAA
CAACGGGAACCGCACCAAGACGGCCAAGGACCTGGGAGTGGACCCGCGCACCATCTTCCGGCATCTGGAGAAGCTGGAAG
CGGAGAAGTCAGGGCGGCCCCTGCCGCCCGAGGAGGGAGACGAGCTGCTCTAG

Upstream 100 bases:

>100_bases
AAGACGTACACGCGCGTGGGCCTCTACCCGACCCGCGGCGGACTCGGCGCCGGTCTCACCCTCTCCTTCTGACGGAGACT
CCCTCCAGGTACGTGAAGCC

Downstream 100 bases:

>100_bases
GGGAGCAGCCCGTCCGGATGATGGAAGCGACGACGCGGCGATACTCCTGGAGACGAGAGCTGTGGCTGCTGATGGCCGCG
GGCTGCGCCGCGTCCGGCTG

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 630; Mature: 629

Protein sequence:

>630_residues
MASLTVRTPDGKIRAVSLHKRLTSIGRGPDNDIPLEDTSVPASALHVTFDGTRYEVGSLGATFHVNGKKRDAHALSTGDV
VRVGHTELIFARDDAPRAPPLPASPPRELIHTSNPDSHTSELPGVPGRELLLLRRLTAFSERLLGLYDLERLLEGLMDEA
IEVTRADKGFLILMENGDPRVKVARNVSRENIEDAVEKDKISDSIIAKVVKEQKALIVADALDSPEFNKSESVVNLRVHS
VMCVPLMQKGDLFGVLYVGNDRLVNRFEPKSADMLTIFAAQASLILQNAMLVSDLKLDNTELRRKLEDQRYGDIVGACQG
MRDVYKRIDKIAPTDISVLITGETGTGKELIAREIHRRSTRAKGPFITINCGAIPENLLESELFGHVKGAFTGAVATKAG
KFQAAIGGTLFLDEIGEMPLQLQVKLLRALQEKVVYKVGDNRGEPVDIRVVAATNKVLEDEVKKNTFREDLYYRLNVVTL
KLPPLRERGEDVVVLGRFFLQKYAREFSSKARGFTPSATVSMRKYGWPGNIRELENRLKKAVVLADKPLLGPDDLDLKPE
NLEPIMPLLQAKEEFQKRYINEVLARNNGNRTKTAKDLGVDPRTIFRHLEKLEAEKSGRPLPPEEGDELL

Sequences:

>Translated_630_residues
MASLTVRTPDGKIRAVSLHKRLTSIGRGPDNDIPLEDTSVPASALHVTFDGTRYEVGSLGATFHVNGKKRDAHALSTGDV
VRVGHTELIFARDDAPRAPPLPASPPRELIHTSNPDSHTSELPGVPGRELLLLRRLTAFSERLLGLYDLERLLEGLMDEA
IEVTRADKGFLILMENGDPRVKVARNVSRENIEDAVEKDKISDSIIAKVVKEQKALIVADALDSPEFNKSESVVNLRVHS
VMCVPLMQKGDLFGVLYVGNDRLVNRFEPKSADMLTIFAAQASLILQNAMLVSDLKLDNTELRRKLEDQRYGDIVGACQG
MRDVYKRIDKIAPTDISVLITGETGTGKELIAREIHRRSTRAKGPFITINCGAIPENLLESELFGHVKGAFTGAVATKAG
KFQAAIGGTLFLDEIGEMPLQLQVKLLRALQEKVVYKVGDNRGEPVDIRVVAATNKVLEDEVKKNTFREDLYYRLNVVTL
KLPPLRERGEDVVVLGRFFLQKYAREFSSKARGFTPSATVSMRKYGWPGNIRELENRLKKAVVLADKPLLGPDDLDLKPE
NLEPIMPLLQAKEEFQKRYINEVLARNNGNRTKTAKDLGVDPRTIFRHLEKLEAEKSGRPLPPEEGDELL
>Mature_629_residues
ASLTVRTPDGKIRAVSLHKRLTSIGRGPDNDIPLEDTSVPASALHVTFDGTRYEVGSLGATFHVNGKKRDAHALSTGDVV
RVGHTELIFARDDAPRAPPLPASPPRELIHTSNPDSHTSELPGVPGRELLLLRRLTAFSERLLGLYDLERLLEGLMDEAI
EVTRADKGFLILMENGDPRVKVARNVSRENIEDAVEKDKISDSIIAKVVKEQKALIVADALDSPEFNKSESVVNLRVHSV
MCVPLMQKGDLFGVLYVGNDRLVNRFEPKSADMLTIFAAQASLILQNAMLVSDLKLDNTELRRKLEDQRYGDIVGACQGM
RDVYKRIDKIAPTDISVLITGETGTGKELIAREIHRRSTRAKGPFITINCGAIPENLLESELFGHVKGAFTGAVATKAGK
FQAAIGGTLFLDEIGEMPLQLQVKLLRALQEKVVYKVGDNRGEPVDIRVVAATNKVLEDEVKKNTFREDLYYRLNVVTLK
LPPLRERGEDVVVLGRFFLQKYAREFSSKARGFTPSATVSMRKYGWPGNIRELENRLKKAVVLADKPLLGPDDLDLKPEN
LEPIMPLLQAKEEFQKRYINEVLARNNGNRTKTAKDLGVDPRTIFRHLEKLEAEKSGRPLPPEEGDELL

Specific function: Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54 [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=343, Percent_Identity=46.3556851311953, Blast_Score=291, Evalue=1e-79,
Organism=Escherichia coli, GI1790437, Length=303, Percent_Identity=45.8745874587459, Blast_Score=265, Evalue=6e-72,
Organism=Escherichia coli, GI1789233, Length=318, Percent_Identity=44.6540880503145, Blast_Score=263, Evalue=3e-71,
Organism=Escherichia coli, GI87082117, Length=274, Percent_Identity=48.5401459854015, Blast_Score=261, Evalue=8e-71,
Organism=Escherichia coli, GI1790299, Length=331, Percent_Identity=41.0876132930514, Blast_Score=258, Evalue=7e-70,
Organism=Escherichia coli, GI1788905, Length=308, Percent_Identity=42.8571428571429, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI87082152, Length=401, Percent_Identity=38.1546134663342, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI1789087, Length=397, Percent_Identity=37.0277078085642, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1786524, Length=372, Percent_Identity=41.1290322580645, Blast_Score=232, Evalue=7e-62,
Organism=Escherichia coli, GI87081872, Length=251, Percent_Identity=43.8247011952191, Blast_Score=205, Evalue=7e-54,
Organism=Escherichia coli, GI1787583, Length=302, Percent_Identity=39.0728476821192, Blast_Score=199, Evalue=5e-52,
Organism=Escherichia coli, GI1789828, Length=236, Percent_Identity=36.0169491525424, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI87081858, Length=233, Percent_Identity=31.3304721030043, Blast_Score=115, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003018
- InterPro:   IPR009057
- InterPro:   IPR002078 [H]

Pfam domain/function: PF01590 GAF; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 69983; Mature: 69852

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLTVRTPDGKIRAVSLHKRLTSIGRGPDNDIPLEDTSVPASALHVTFDGTRYEVGSLG
CCEEEEECCCCCEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCEEEECCCC
ATFHVNGKKRDAHALSTGDVVRVGHTELIFARDDAPRAPPLPASPPRELIHTSNPDSHTS
EEEEECCCCCCCCCCCCCCEEEECCEEEEEEECCCCCCCCCCCCCHHHHHCCCCCCCCHH
ELPGVPGRELLLLRRLTAFSERLLGLYDLERLLEGLMDEAIEVTRADKGFLILMENGDPR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
VKVARNVSRENIEDAVEKDKISDSIIAKVVKEQKALIVADALDSPEFNKSESVVNLRVHS
EEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCEEEEEEEE
VMCVPLMQKGDLFGVLYVGNDRLVNRFEPKSADMLTIFAAQASLILQNAMLVSDLKLDNT
EEEEEHHCCCCEEEEEEECCCHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCHH
ELRRKLEDQRYGDIVGACQGMRDVYKRIDKIAPTDISVLITGETGTGKELIAREIHRRST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHC
RAKGPFITINCGAIPENLLESELFGHVKGAFTGAVATKAGKFQAAIGGTLFLDEIGEMPL
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHCCEEEHHHHCCCCH
QLQVKLLRALQEKVVYKVGDNRGEPVDIRVVAATNKVLEDEVKKNTFREDLYYRLNVVTL
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHEEEEEEEEE
KLPPLRERGEDVVVLGRFFLQKYAREFSSKARGFTPSATVSMRKYGWPGNIRELENRLKK
ECCCHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEHCCCCCCCCHHHHHHHHHH
AVVLADKPLLGPDDLDLKPENLEPIMPLLQAKEEFQKRYINEVLARNNGNRTKTAKDLGV
HEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCC
DPRTIFRHLEKLEAEKSGRPLPPEEGDELL
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
ASLTVRTPDGKIRAVSLHKRLTSIGRGPDNDIPLEDTSVPASALHVTFDGTRYEVGSLG
CEEEEECCCCCEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCEEEECCCC
ATFHVNGKKRDAHALSTGDVVRVGHTELIFARDDAPRAPPLPASPPRELIHTSNPDSHTS
EEEEECCCCCCCCCCCCCCEEEECCEEEEEEECCCCCCCCCCCCCHHHHHCCCCCCCCHH
ELPGVPGRELLLLRRLTAFSERLLGLYDLERLLEGLMDEAIEVTRADKGFLILMENGDPR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
VKVARNVSRENIEDAVEKDKISDSIIAKVVKEQKALIVADALDSPEFNKSESVVNLRVHS
EEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCEEEEEEEE
VMCVPLMQKGDLFGVLYVGNDRLVNRFEPKSADMLTIFAAQASLILQNAMLVSDLKLDNT
EEEEEHHCCCCEEEEEEECCCHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCHH
ELRRKLEDQRYGDIVGACQGMRDVYKRIDKIAPTDISVLITGETGTGKELIAREIHRRST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHC
RAKGPFITINCGAIPENLLESELFGHVKGAFTGAVATKAGKFQAAIGGTLFLDEIGEMPL
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHCCEEEHHHHCCCCH
QLQVKLLRALQEKVVYKVGDNRGEPVDIRVVAATNKVLEDEVKKNTFREDLYYRLNVVTL
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHEEEEEEEEE
KLPPLRERGEDVVVLGRFFLQKYAREFSSKARGFTPSATVSMRKYGWPGNIRELENRLKK
ECCCHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEHCCCCCCCCHHHHHHHHHH
AVVLADKPLLGPDDLDLKPENLEPIMPLLQAKEEFQKRYINEVLARNNGNRTKTAKDLGV
HEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCC
DPRTIFRHLEKLEAEKSGRPLPPEEGDELL
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA