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The map label for this gene is czcB [H]

Identifier: 108758865

GI number: 108758865

Start: 1137203

End: 1138402

Strand: Reverse

Name: czcB [H]

Synonym: MXAN_0984

Alternate gene names: 108758865

Gene position: 1138402-1137203 (Counterclockwise)

Preceding gene: 108757618

Following gene: 108763556

Centisome position: 12.46

GC content: 72.0

Gene sequence:

>1200_bases
ATGAAGCCCCTCCACGCCGCAGTGGCCGCCCTCCTCCTGCTCACCGCCTGCAAGCGCGAGACGCCGCACGACGCGCAAGC
GCACGGACATGACGAGCCCCCCGCCCAGGCAGGTGCCCACCACGACGACCATGGCGAGCCCCACGTCCGCATCGCGTCGG
AGATGTTGAGAGACTTGCGCATCACCACCGCGCCCGTGGGCGTGCGACCGGGCGGTGAGAATGTCACCGTCCTAGGAGAG
CTCACCTTCAGCGAGGACGCCTACGCGGAGGTGGCCTCCCCCATCGCCGCCCGCGTGAGCGCCGTCTTCGTCACCACCGG
TCAGGCGGTGAAGCAGGGCGAAAAGCTCGCGGACCTGCGCAGCCCCGAGCTGGGCAAGGCGCGCGCGGCGCTGCAAGCGG
CCCAGGCCCAGGCCCAGGCCGCGCGTCAGGCCGCCGAGCGCAAGCGCACGCTCGCTGACGAGCGCATCATCGCGAGCAAG
GACGTGCAAGCCGCCGAAGCAGAGGCCGCCGCCGCCGAGGCCTCGGTCGCCGCCGCGCGCGCGGAGCTGGTGGCCCTGGG
CGTGAGCGAAGAAGAGCTGCGCGGTGGCAACGTCCCCCCGGGCTTCGTCCTGCGCGCCCCCCTGTCCGGCACCGTCGTCG
AACGCACCGCGAGGATGGGGCAGATGGCGGACCCCAACCTGCCGCTGTTCTGCATTGGTGACGTGTCCTCGCTGTGGCTG
GTGGTGCACGCCTTCGAGCGTGACGCCGTGCGCATCCAGCGTGGCACGCAGGCCCGCATCACCTTCGCGGCCTTTCCGGG
CCAGGAGTTCATGGCGAAGGTGGGCCACGTGGGGCAGCGCGTGGACGCGACTTCACGCACCATCCCCGTGAGGCTGGAGC
TGGACAACGCCGACGGCCAACTTCGGCCCGGCATGTCCGCGTCGGCCTACATCCCGTTGGGGGACCCGGGAGCGCCCATC
ACCGCCGTGCCCGCGGCGGCGCTCCAGCGGCTGGAAGGTGGCTGGGTGGCCTTCCTGCCCACTGACACGCGCGGCGTCTT
CGAGCGACGCGAGGTGGGCCGGGGCCGCACCCTGGGCGGCGACGTGGAGGTCCTCACCGGACTGAAGCCTGGCGAGCAGG
TGGTGGTGGAAGGCGCGTTCCTGCTCAAGGCGGAGGCGGAGAAGTTGAGCGGCGGAGGGAGTGACGGCCATGCGCACTGA

Upstream 100 bases:

>100_bases
TTCGCCGCGACACGCTGGAAGCGCGTGCCGCCTACCTCGACAGCCTCCTTCAGGCAGCCCTCTCCCGCGTCCAACTGGCC
GTGGAGACCGGAGCCCTTCC

Downstream 100 bases:

>100_bases
GGCCCCCGACTCCTGGATGAACCGCATCCTGCGGTCCTCCTTCGCCCGGCCTGGTCTCACCGTGGTGCTGGCCCTGGCGC
TCTCCGCCTTCGGCGCGGTG

Product: RND family heavy metal efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MKPLHAAVAALLLLTACKRETPHDAQAHGHDEPPAQAGAHHDDHGEPHVRIASEMLRDLRITTAPVGVRPGGENVTVLGE
LTFSEDAYAEVASPIAARVSAVFVTTGQAVKQGEKLADLRSPELGKARAALQAAQAQAQAARQAAERKRTLADERIIASK
DVQAAEAEAAAAEASVAAARAELVALGVSEEELRGGNVPPGFVLRAPLSGTVVERTARMGQMADPNLPLFCIGDVSSLWL
VVHAFERDAVRIQRGTQARITFAAFPGQEFMAKVGHVGQRVDATSRTIPVRLELDNADGQLRPGMSASAYIPLGDPGAPI
TAVPAAALQRLEGGWVAFLPTDTRGVFERREVGRGRTLGGDVEVLTGLKPGEQVVVEGAFLLKAEAEKLSGGGSDGHAH

Sequences:

>Translated_399_residues
MKPLHAAVAALLLLTACKRETPHDAQAHGHDEPPAQAGAHHDDHGEPHVRIASEMLRDLRITTAPVGVRPGGENVTVLGE
LTFSEDAYAEVASPIAARVSAVFVTTGQAVKQGEKLADLRSPELGKARAALQAAQAQAQAARQAAERKRTLADERIIASK
DVQAAEAEAAAAEASVAAARAELVALGVSEEELRGGNVPPGFVLRAPLSGTVVERTARMGQMADPNLPLFCIGDVSSLWL
VVHAFERDAVRIQRGTQARITFAAFPGQEFMAKVGHVGQRVDATSRTIPVRLELDNADGQLRPGMSASAYIPLGDPGAPI
TAVPAAALQRLEGGWVAFLPTDTRGVFERREVGRGRTLGGDVEVLTGLKPGEQVVVEGAFLLKAEAEKLSGGGSDGHAH
>Mature_399_residues
MKPLHAAVAALLLLTACKRETPHDAQAHGHDEPPAQAGAHHDDHGEPHVRIASEMLRDLRITTAPVGVRPGGENVTVLGE
LTFSEDAYAEVASPIAARVSAVFVTTGQAVKQGEKLADLRSPELGKARAALQAAQAQAQAARQAAERKRTLADERIIASK
DVQAAEAEAAAAEASVAAARAELVALGVSEEELRGGNVPPGFVLRAPLSGTVVERTARMGQMADPNLPLFCIGDVSSLWL
VVHAFERDAVRIQRGTQARITFAAFPGQEFMAKVGHVGQRVDATSRTIPVRLELDNADGQLRPGMSASAYIPLGDPGAPI
TAVPAAALQRLEGGWVAFLPTDTRGVFERREVGRGRTLGGDVEVLTGLKPGEQVVVEGAFLLKAEAEKLSGGGSDGHAH

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=366, Percent_Identity=25.6830601092896, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87081796, Length=346, Percent_Identity=24.8554913294798, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41845; Mature: 41845

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLHAAVAALLLLTACKRETPHDAQAHGHDEPPAQAGAHHDDHGEPHVRIASEMLRDLR
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHCE
ITTAPVGVRPGGENVTVLGELTFSEDAYAEVASPIAARVSAVFVTTGQAVKQGEKLADLR
EEECCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHEEEEEECCHHHHCCHHHHHCC
SPELGKARAALQAAQAQAQAARQAAERKRTLADERIIASKDVQAAEAEAAAAEASVAAAR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AELVALGVSEEELRGGNVPPGFVLRAPLSGTVVERTARMGQMADPNLPLFCIGDVSSLWL
HHHEEECCCHHHHCCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCEEEECCHHHHHH
VVHAFERDAVRIQRGTQARITFAAFPGQEFMAKVGHVGQRVDATSRTIPVRLELDNADGQ
HHHHHHCCCEEEECCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCC
LRPGMSASAYIPLGDPGAPITAVPAAALQRLEGGWVAFLPTDTRGVFERREVGRGRTLGG
CCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCCCC
DVEVLTGLKPGEQVVVEGAFLLKAEAEKLSGGGSDGHAH
CCCEEECCCCCCEEEEECEEEEEEHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKPLHAAVAALLLLTACKRETPHDAQAHGHDEPPAQAGAHHDDHGEPHVRIASEMLRDLR
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHCE
ITTAPVGVRPGGENVTVLGELTFSEDAYAEVASPIAARVSAVFVTTGQAVKQGEKLADLR
EEECCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHEEEEEECCHHHHCCHHHHHCC
SPELGKARAALQAAQAQAQAARQAAERKRTLADERIIASKDVQAAEAEAAAAEASVAAAR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AELVALGVSEEELRGGNVPPGFVLRAPLSGTVVERTARMGQMADPNLPLFCIGDVSSLWL
HHHEEECCCHHHHCCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCEEEECCHHHHHH
VVHAFERDAVRIQRGTQARITFAAFPGQEFMAKVGHVGQRVDATSRTIPVRLELDNADGQ
HHHHHHCCCEEEECCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCC
LRPGMSASAYIPLGDPGAPITAVPAAALQRLEGGWVAFLPTDTRGVFERREVGRGRTLGG
CCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCCCC
DVEVLTGLKPGEQVVVEGAFLLKAEAEKLSGGGSDGHAH
CCCEEECCCCCCEEEEECEEEEEEHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]