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The map label for this gene is czcC [H]

Identifier: 108757618

GI number: 108757618

Start: 1138399

End: 1139661

Strand: Reverse

Name: czcC [H]

Synonym: MXAN_0985

Alternate gene names: 108757618

Gene position: 1139661-1138399 (Counterclockwise)

Preceding gene: 108757229

Following gene: 108758865

Centisome position: 12.47

GC content: 72.21

Gene sequence:

>1263_bases
GTGCCCCATCCACTCACGGTGGCAGCCTTCGGGCTCGCCGCCACACTCCTATTTCCGCGTGTCGCCGCGGCCCAGCCGGG
CTCCGCCGATGCCGCGCTGTCCCTTGAAGAAACCCTGGTCCTGGCCCGCCAGCGTGCACCCGCGCTGCTGGATGCCGCGG
GCCGCGCCGCCGAGGCCCAGGGCCCCGTGGCGGCCGCCAGGTCGCTGCTGAACGACAACCCCACCTTCGAGCTCCAGGCG
GGCCCGCGCAGTGCCCCTGGCTCGCCGGGAAACCCCGCCGTGCGTGGGTTGGACTTGAGCGTGGGCATCAGCCAGTCCTT
CGAGCTGGGTGGAAAGCGCGGCGCCCGCCGGGAATCCGCGCGCGCCGGTCTGGAGATGGCGACGGCCCACCAGCGCGACG
CCGAGCGCCGGGTGCTGGGTGACGTCGCCGCGCGCTTCCTCCAGGCGCTGCATGCGCGGGAGCGGCTGAGCCTCGCGCGA
GAAGCCGAGGCCGCCGCCCGGGAGACCGCGAACTCCGCCCAGCGGCGCTTCGAGGCCGGTGATGTGCCCGTGGTGGACGT
CAACGTGGCGCGCGTGTCCCTGGCCCGCATGCGCGCGGAGGTGGCCACCGCGGAGGGGGACGAGGCCGTCCAACTCCACC
AGTTGCGCGCGATGTTGGGCCTTCCGCTCACACATCCGTTGGCCATCCGCGGTGAGCTGCGAGTGCTCGCGCTCCAGCCT
GTCACGGAGGCGAAGACAGACACCGTGGCGGCGCGGCCCGATATCGCCGCGTTGGAAGCGGAGCTCGCCCAGGCGGATGC
CGACCGCCGCATGGGCCGGGCGAGCGTCTGGCCAGACATCACCGCGGGGTTTCTGTACCAGCGAGAGATTGATGAAATCG
CCTACCTCGGCGCCCTGAGCGTGCCGCTGCCGCTCTTCGACCGGGGAGACAACGCCCGGGTGACGGGCGAGGCCCGCGTG
CGCCGGCTCCAATCCCTGCTGGCGGCGGCCCGGTTGGAAGTGGACGTCCAGGTGGAGGCCGCGCGCGTGCAGCACCGCAA
GCGGCTGGAAGCCGTGACGCTGCTGGAAGCCGACGCCCTGCCGCTGCTCAGTGACAACGAAAGTCTCGCTCGCCGCTCCT
ACGAAGCCGGAGAGATGGGCCTCGCCGAGTTCCTCCTCGTTCGCCGCGACACGCTGGAAGCGCGTGCCGCCTACCTCGAC
AGCCTCCTTCAGGCAGCCCTCTCCCGCGTCCAACTGGCCGTGGAGACCGGAGCCCTTCCATGA

Upstream 100 bases:

>100_bases
GCCGTCTCGTTCGCTCGTGTCCGCCAGGACGGGTGTGCCCGTGTGTCATCGCGGGGCACGCTCCACCTGACGCACGCCTC
CTTTTCGCGAGGTCATCGCC

Downstream 100 bases:

>100_bases
AGCCCCTCCACGCCGCAGTGGCCGCCCTCCTCCTGCTCACCGCCTGCAAGCGCGAGACGCCGCACGACGCGCAAGCGCAC
GGACATGACGAGCCCCCCGC

Product: putative cobalt-zinc-cadmium resistance protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MPHPLTVAAFGLAATLLFPRVAAAQPGSADAALSLEETLVLARQRAPALLDAAGRAAEAQGPVAAARSLLNDNPTFELQA
GPRSAPGSPGNPAVRGLDLSVGISQSFELGGKRGARRESARAGLEMATAHQRDAERRVLGDVAARFLQALHARERLSLAR
EAEAAARETANSAQRRFEAGDVPVVDVNVARVSLARMRAEVATAEGDEAVQLHQLRAMLGLPLTHPLAIRGELRVLALQP
VTEAKTDTVAARPDIAALEAELAQADADRRMGRASVWPDITAGFLYQREIDEIAYLGALSVPLPLFDRGDNARVTGEARV
RRLQSLLAAARLEVDVQVEAARVQHRKRLEAVTLLEADALPLLSDNESLARRSYEAGEMGLAEFLLVRRDTLEARAAYLD
SLLQAALSRVQLAVETGALP

Sequences:

>Translated_420_residues
MPHPLTVAAFGLAATLLFPRVAAAQPGSADAALSLEETLVLARQRAPALLDAAGRAAEAQGPVAAARSLLNDNPTFELQA
GPRSAPGSPGNPAVRGLDLSVGISQSFELGGKRGARRESARAGLEMATAHQRDAERRVLGDVAARFLQALHARERLSLAR
EAEAAARETANSAQRRFEAGDVPVVDVNVARVSLARMRAEVATAEGDEAVQLHQLRAMLGLPLTHPLAIRGELRVLALQP
VTEAKTDTVAARPDIAALEAELAQADADRRMGRASVWPDITAGFLYQREIDEIAYLGALSVPLPLFDRGDNARVTGEARV
RRLQSLLAAARLEVDVQVEAARVQHRKRLEAVTLLEADALPLLSDNESLARRSYEAGEMGLAEFLLVRRDTLEARAAYLD
SLLQAALSRVQLAVETGALP
>Mature_419_residues
PHPLTVAAFGLAATLLFPRVAAAQPGSADAALSLEETLVLARQRAPALLDAAGRAAEAQGPVAAARSLLNDNPTFELQAG
PRSAPGSPGNPAVRGLDLSVGISQSFELGGKRGARRESARAGLEMATAHQRDAERRVLGDVAARFLQALHARERLSLARE
AEAAARETANSAQRRFEAGDVPVVDVNVARVSLARMRAEVATAEGDEAVQLHQLRAMLGLPLTHPLAIRGELRVLALQPV
TEAKTDTVAARPDIAALEAELAQADADRRMGRASVWPDITAGFLYQREIDEIAYLGALSVPLPLFDRGDNARVTGEARVR
RLQSLLAAARLEVDVQVEAARVQHRKRLEAVTLLEADALPLLSDNESLARRSYEAGEMGLAEFLLVRRDTLEARAAYLDS
LLQAALSRVQLAVETGALP

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 44810; Mature: 44678

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHPLTVAAFGLAATLLFPRVAAAQPGSADAALSLEETLVLARQRAPALLDAAGRAAEAQ
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCC
GPVAAARSLLNDNPTFELQAGPRSAPGSPGNPAVRGLDLSVGISQSFELGGKRGARRESA
CHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCEEEEEEEECCCCHHHCCCCCCCCHHHH
RAGLEMATAHQRDAERRVLGDVAARFLQALHARERLSLAREAEAAARETANSAQRRFEAG
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DVPVVDVNVARVSLARMRAEVATAEGDEAVQLHQLRAMLGLPLTHPLAIRGELRVLALQP
CCCEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECC
VTEAKTDTVAARPDIAALEAELAQADADRRMGRASVWPDITAGFLYQREIDEIAYLGALS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
VPLPLFDRGDNARVTGEARVRRLQSLLAAARLEVDVQVEAARVQHRKRLEAVTLLEADAL
CCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCCC
PLLSDNESLARRSYEAGEMGLAEFLLVRRDTLEARAAYLDSLLQAALSRVQLAVETGALP
CCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PHPLTVAAFGLAATLLFPRVAAAQPGSADAALSLEETLVLARQRAPALLDAAGRAAEAQ
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCC
GPVAAARSLLNDNPTFELQAGPRSAPGSPGNPAVRGLDLSVGISQSFELGGKRGARRESA
CHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCEEEEEEEECCCCHHHCCCCCCCCHHHH
RAGLEMATAHQRDAERRVLGDVAARFLQALHARERLSLAREAEAAARETANSAQRRFEAG
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DVPVVDVNVARVSLARMRAEVATAEGDEAVQLHQLRAMLGLPLTHPLAIRGELRVLALQP
CCCEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECC
VTEAKTDTVAARPDIAALEAELAQADADRRMGRASVWPDITAGFLYQREIDEIAYLGALS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
VPLPLFDRGDNARVTGEARVRRLQSLLAAARLEVDVQVEAARVQHRKRLEAVTLLEADAL
CCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCCC
PLLSDNESLARRSYEAGEMGLAEFLLVRRDTLEARAAYLDSLLQAALSRVQLAVETGALP
CCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]