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The map label for this gene is cdd [H]

Identifier: 108758788

GI number: 108758788

Start: 7073975

End: 7074379

Strand: Reverse

Name: cdd [H]

Synonym: MXAN_5706

Alternate gene names: 108758788

Gene position: 7074379-7073975 (Counterclockwise)

Preceding gene: 108762041

Following gene: 108760686

Centisome position: 77.4

GC content: 71.36

Gene sequence:

>405_bases
ATGGCGGACGAGATTCCCTGGGAGCGCCTGTTTGAGGAAGCCGCGCGCGTGCGAGCGCGCGCCCACGTGCCCTATTCGCG
GTTCCCCGTAGGGGCCGCCGTCCTCTTTGCGGACGGCGCCGTGGTGGCCGGCTGCAACGTGGAGAACGCCACCTACGGGC
TCACCGTCTGCGCGGAGCGCAATGCCTTCGCGGCGGCCGTGGCCCAGGGGCACACCCAGCCGGTGGCCGTGGCCATCGTC
GTGGACACCCCCGAGCCCTGTCCTCCGTGCGGCATGTGCCGCCAGGTCATGGCCGAGTTTGGCGGGCAGGAGCTGCCCGT
ACGCAGCCGGACGCCCCAGGGCGGCGAGGCGCGCTACACCCTGGGAGGCCTGCTGCCGCATGCCTTCACCAAAGACTTCT
TCTAG

Upstream 100 bases:

>100_bases
GTGGAGTCCGAGCTGGCCATCGCGCGCCACCTGGATGATGTGCAGAGCGGCACGGCCCGCTCGTAACGGACCTCAATCCG
GCTTCGTGTAGGAGGGCGTC

Downstream 100 bases:

>100_bases
CGAGAGAGCCTGAGCACGCCGTGGATTTGCTCCTGACTGGTGGCACGGTTGTAACGATGAACCGCGAGCGCGAGGTGCTC
GTGGATGCGGACGTCCTCGT

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 134; Mature: 133

Protein sequence:

>134_residues
MADEIPWERLFEEAARVRARAHVPYSRFPVGAAVLFADGAVVAGCNVENATYGLTVCAERNAFAAAVAQGHTQPVAVAIV
VDTPEPCPPCGMCRQVMAEFGGQELPVRSRTPQGGEARYTLGGLLPHAFTKDFF

Sequences:

>Translated_134_residues
MADEIPWERLFEEAARVRARAHVPYSRFPVGAAVLFADGAVVAGCNVENATYGLTVCAERNAFAAAVAQGHTQPVAVAIV
VDTPEPCPPCGMCRQVMAEFGGQELPVRSRTPQGGEARYTLGGLLPHAFTKDFF
>Mature_133_residues
ADEIPWERLFEEAARVRARAHVPYSRFPVGAAVLFADGAVVAGCNVENATYGLTVCAERNAFAAAVAQGHTQPVAVAIVV
DTPEPCPPCGMCRQVMAEFGGQELPVRSRTPQGGEARYTLGGLLPHAFTKDFF

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=123, Percent_Identity=43.0894308943089, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17540514, Length=111, Percent_Identity=51.3513513513513, Blast_Score=115, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17551074, Length=123, Percent_Identity=39.8373983739837, Blast_Score=99, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6323274, Length=125, Percent_Identity=34.4, Blast_Score=80, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24582741, Length=128, Percent_Identity=35.9375, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI19920920, Length=102, Percent_Identity=45.0980392156863, Blast_Score=83, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24582744, Length=99, Percent_Identity=40.4040404040404, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14320; Mature: 14189

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADEIPWERLFEEAARVRARAHVPYSRFPVGAAVLFADGAVVAGCNVENATYGLTVCAER
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEECCCCCCCEEEEEEEECC
NAFAAAVAQGHTQPVAVAIVVDTPEPCPPCGMCRQVMAEFGGQELPVRSRTPQGGEARYT
CHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
LGGLLPHAFTKDFF
CCCCCHHHHHCCCC
>Mature Secondary Structure 
ADEIPWERLFEEAARVRARAHVPYSRFPVGAAVLFADGAVVAGCNVENATYGLTVCAER
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEECCCCCCCEEEEEEEECC
NAFAAAVAQGHTQPVAVAIVVDTPEPCPPCGMCRQVMAEFGGQELPVRSRTPQGGEARYT
CHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
LGGLLPHAFTKDFF
CCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]