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The map label for this gene is mtaD [H]

Identifier: 108760686

GI number: 108760686

Start: 7072608

End: 7073954

Strand: Reverse

Name: mtaD [H]

Synonym: MXAN_5705

Alternate gene names: 108760686

Gene position: 7073954-7072608 (Counterclockwise)

Preceding gene: 108758788

Following gene: 108761018

Centisome position: 77.4

GC content: 71.34

Gene sequence:

>1347_bases
GTGGATTTGCTCCTGACTGGTGGCACGGTTGTAACGATGAACCGCGAGCGCGAGGTGCTCGTGGATGCGGACGTCCTCGT
CCAGGATGGCCGCATCGCCAAGGTGGGCCGGGGCCTCAAGCCTCGCGGCACCCGGCGGGTGGTGGACGTGACGGGAAAGG
TGGTGCTGCCGGGCCTCATCCACGGCCACCTCCACGCTTGTCAGACGCTCTTTCGTGGCCGCGCGGACGGGCTGGAGTTG
CTGGACTGGCTCCGCGAGCGCATCTGGCCCTTCGAGGCCTCGCACGACGCCGCGTCCATGCGGGCCTCGGCGGACCTGAC
CTTCGCGGAGCTCATCCGCTCGGGCGCCACGGCGGCGCTCGATATGGGCAGCGTGTACCACTACGACGCCGTCTTCGAGT
CGGCGCGGGACTCCGGCTTCCGGCTGGTGGGCGGCAAGGCGATGATGGACGCGGGCGCGGGCGTCCCCGCGGGCCTGCGT
GAGAGCACCGAGGACTCCCTGAAGGAGAGCCTCGCCCTGAAGGAGCGCTGGCACGGCACGCACGGCGGCCGGCTGCGCTA
CGCCTTCGCCCCGCGCTTCGTGCTGTCCTGCACCCCGGAGCTGCTGCGCGAGGTGGCGCGGCTGGCCAAGGAGCACGGGC
TGCGCATCCACACCCACGCCAGTGAGAACGCGAAGGAGACGGACGCGGTCCGCCAGTACACCGGTGGCGAGGACAACGTG
GCCTTCTTCCACACGGTGGGGATGTCCGGCCCGCACGTGACGATGGCCCACTGCGTGTGGCTGTCCCAGGAGGAGCAGGA
CATCCTGCGCGACACCCGCACGGTGGTGTGCCACTGCCCCGGCTCCAACCTCAAGCTGGCGTCGGGCATCGCCAAGGTGC
CGGAGTTGCTGGAGGCCGGCGTGGCGGTGGCGCTGGGCGCGGACGGTGCGCCCTGCAACAACACGCTCGACATCTTCTAC
GAGATGAAGCTCGCCGCGGTGATGCACAACCCGCGCGTGGGGCCGTGCGCGATGACGCCCATGCGCGTGCTGGAGATGGC
CACGCTGCACGGCGCCCGGGCGCTGGGCCTGGAGGACGAGGTGGGCTCGCTGGAGCCCGGCAAGCGCGCCGACATCACCG
TGGTGGACGTCAGCGGCCTGCACGCGGGCCCCACGCCCGAGGACGTGCTGGTGCCGCTGGTGCACTCCGCGCGGGGCAGC
GACGTGGCGCACGTCTTCATCGACGGCCAGCCGGTGCTGCGCGATGGGGTGCTCACCACGTTGGACGCGCCCTCCGTCCT
GGCGAACGCGAACGCGCAGGTGGCGCGCATCCTCAAGCGCCGCCAGAAGAAGGCGCGCAGCGGCTGA

Upstream 100 bases:

>100_bases
GCCGGACGCCCCAGGGCGGCGAGGCGCGCTACACCCTGGGAGGCCTGCTGCCGCATGCCTTCACCAAAGACTTCTTCTAG
CGAGAGAGCCTGAGCACGCC

Downstream 100 bases:

>100_bases
GGCTCAGGCCGGCAGCCGCAGCACGAAGGACGTGGACCATCCGGGCGCGTCCTCCACCGCCAACCGCCCGCCGTGGGCCT
CCGCGGCGAGCCGGCAGAAG

Product: N-ethylammeline chlorohydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MDLLLTGGTVVTMNREREVLVDADVLVQDGRIAKVGRGLKPRGTRRVVDVTGKVVLPGLIHGHLHACQTLFRGRADGLEL
LDWLRERIWPFEASHDAASMRASADLTFAELIRSGATAALDMGSVYHYDAVFESARDSGFRLVGGKAMMDAGAGVPAGLR
ESTEDSLKESLALKERWHGTHGGRLRYAFAPRFVLSCTPELLREVARLAKEHGLRIHTHASENAKETDAVRQYTGGEDNV
AFFHTVGMSGPHVTMAHCVWLSQEEQDILRDTRTVVCHCPGSNLKLASGIAKVPELLEAGVAVALGADGAPCNNTLDIFY
EMKLAAVMHNPRVGPCAMTPMRVLEMATLHGARALGLEDEVGSLEPGKRADITVVDVSGLHAGPTPEDVLVPLVHSARGS
DVAHVFIDGQPVLRDGVLTTLDAPSVLANANAQVARILKRRQKKARSG

Sequences:

>Translated_448_residues
MDLLLTGGTVVTMNREREVLVDADVLVQDGRIAKVGRGLKPRGTRRVVDVTGKVVLPGLIHGHLHACQTLFRGRADGLEL
LDWLRERIWPFEASHDAASMRASADLTFAELIRSGATAALDMGSVYHYDAVFESARDSGFRLVGGKAMMDAGAGVPAGLR
ESTEDSLKESLALKERWHGTHGGRLRYAFAPRFVLSCTPELLREVARLAKEHGLRIHTHASENAKETDAVRQYTGGEDNV
AFFHTVGMSGPHVTMAHCVWLSQEEQDILRDTRTVVCHCPGSNLKLASGIAKVPELLEAGVAVALGADGAPCNNTLDIFY
EMKLAAVMHNPRVGPCAMTPMRVLEMATLHGARALGLEDEVGSLEPGKRADITVVDVSGLHAGPTPEDVLVPLVHSARGS
DVAHVFIDGQPVLRDGVLTTLDAPSVLANANAQVARILKRRQKKARSG
>Mature_448_residues
MDLLLTGGTVVTMNREREVLVDADVLVQDGRIAKVGRGLKPRGTRRVVDVTGKVVLPGLIHGHLHACQTLFRGRADGLEL
LDWLRERIWPFEASHDAASMRASADLTFAELIRSGATAALDMGSVYHYDAVFESARDSGFRLVGGKAMMDAGAGVPAGLR
ESTEDSLKESLALKERWHGTHGGRLRYAFAPRFVLSCTPELLREVARLAKEHGLRIHTHASENAKETDAVRQYTGGEDNV
AFFHTVGMSGPHVTMAHCVWLSQEEQDILRDTRTVVCHCPGSNLKLASGIAKVPELLEAGVAVALGADGAPCNNTLDIFY
EMKLAAVMHNPRVGPCAMTPMRVLEMATLHGARALGLEDEVGSLEPGKRADITVVDVSGLHAGPTPEDVLVPLVHSARGS
DVAHVFIDGQPVLRDGVLTTLDAPSVLANANAQVARILKRRQKKARSG

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=382, Percent_Identity=28.5340314136126, Blast_Score=153, Evalue=3e-37,
Organism=Escherichia coli, GI1789249, Length=366, Percent_Identity=33.0601092896175, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI87082177, Length=456, Percent_Identity=25, Blast_Score=83, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17540282, Length=396, Percent_Identity=26.010101010101, Blast_Score=99, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6319963, Length=348, Percent_Identity=25.2873563218391, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24643849, Length=391, Percent_Identity=27.6214833759591, Blast_Score=125, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 48240; Mature: 48240

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLLTGGTVVTMNREREVLVDADVLVQDGRIAKVGRGLKPRGTRRVVDVTGKVVLPGLI
CCEEEECCEEEEECCCCEEEEECCEEEECCCCHHHCCCCCCCCCEEEEEECCCEEECHHH
HGHLHACQTLFRGRADGLELLDWLRERIWPFEASHDAASMRASADLTFAELIRSGATAAL
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHCCCCEEE
DMGSVYHYDAVFESARDSGFRLVGGKAMMDAGAGVPAGLRESTEDSLKESLALKERWHGT
ECCCCHHHHHHHHHHCCCCEEEECCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
HGGRLRYAFAPRFVLSCTPELLREVARLAKEHGLRIHTHASENAKETDAVRQYTGGEDNV
CCCEEEEEECCCHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCCCE
AFFHTVGMSGPHVTMAHCVWLSQEEQDILRDTRTVVCHCPGSNLKLASGIAKVPELLEAG
EEEEEECCCCCCEEEEEEEECCCCHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCC
VAVALGADGAPCNNTLDIFYEMKLAAVMHNPRVGPCAMTPMRVLEMATLHGARALGLEDE
EEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
VGSLEPGKRADITVVDVSGLHAGPTPEDVLVPLVHSARGSDVAHVFIDGQPVLRDGVLTT
CCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHCCCEEE
LDAPSVLANANAQVARILKRRQKKARSG
CCCCHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLLLTGGTVVTMNREREVLVDADVLVQDGRIAKVGRGLKPRGTRRVVDVTGKVVLPGLI
CCEEEECCEEEEECCCCEEEEECCEEEECCCCHHHCCCCCCCCCEEEEEECCCEEECHHH
HGHLHACQTLFRGRADGLELLDWLRERIWPFEASHDAASMRASADLTFAELIRSGATAAL
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHCCCCEEE
DMGSVYHYDAVFESARDSGFRLVGGKAMMDAGAGVPAGLRESTEDSLKESLALKERWHGT
ECCCCHHHHHHHHHHCCCCEEEECCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
HGGRLRYAFAPRFVLSCTPELLREVARLAKEHGLRIHTHASENAKETDAVRQYTGGEDNV
CCCEEEEEECCCHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCCCE
AFFHTVGMSGPHVTMAHCVWLSQEEQDILRDTRTVVCHCPGSNLKLASGIAKVPELLEAG
EEEEEECCCCCCEEEEEEEECCCCHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCC
VAVALGADGAPCNNTLDIFYEMKLAAVMHNPRVGPCAMTPMRVLEMATLHGARALGLEDE
EEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
VGSLEPGKRADITVVDVSGLHAGPTPEDVLVPLVHSARGSDVAHVFIDGQPVLRDGVLTT
CCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHCCCEEE
LDAPSVLANANAQVARILKRRQKKARSG
CCCCHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA